摘要:
An anterior spinal fixation system comprises a plurality of mounting constructs to hold one or more spinal rods or spinal plate-type braces. Each mounting construct includes a bottom plate and a top plate assembly. The bottom plate is attached to the vertebral body with a plurality of anchors, one or more of which may be polyaxial. In one embodiment, the top plate assembly engages the bottom plate through a quick-connect feature that provides simple and secure locking as well as tactile feedback. When the top plate assembly is engaged with the bottom plate, it compresses the rods or braces against the head of the screws, locking the angle of any polyaxial bone screws. In another embodiment, the top plate assembly threadably engages the bottom plate. For additional strength and rigidity, cross-connectors may be used between each pair of mounting constructs when two or more spinal rods are used.
摘要:
α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as-inhibitors of HIV protease.
摘要:
A method and system of ozone treatment diverts a portion of water from a flow of water in a conduit; injects an ozone-containing gas into the portion to provide an ozonated portion; recombines the ozonated portion with the flow of water in the conduit; and regulates the diverted portion to provide a minimum diverted portion flow rate according to flow in the conduit and proportion of ozone in the injected gas.
摘要:
A drug-delivery tool and method for delivering a diagnostic or therapeutic agent to a target site within a selected body tissue, such as the myocardium of the heart, is disclosed. The drug-delivery tool generally includes an accessing device having a tissue-penetrating implement in its distal-end region, and elements for delivering a selected agent into a cavity formed by the implement. Methods of use are also described.
摘要:
A biopsy device suitable for collection of a tissue sample from a biopsy site in a body lumen is provided. The biopsy device comprises a combination of an introducer assembly, a cutter assembly, and an endoscope assembly that coact with one another. The introducer assembly includes a hollow sheath having a distal end portion defining an aperture suitable for receiving a tissue mass therein. The cutter assembly includes a cutter tube having a distal end portion with a cutting edge. The cutter tube is sized to fit axially within the introducer sheath. The endoscope assembly includes a bundle of optical fibers sized to fit axially within the cutter tube. In use, the fiber optic bundle of the endoscope is nested within the cutter tube, which in turn is nested within the introducer sheath to form a co-axial structure.
摘要:
Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
摘要:
A drug-delivery tool and method for delivering a diagnostic or therapeutic agent to a target site within a selected body tissue, such as the myocardium of the heart, is disclosed. The drug-delivery tool generally includes an accessing device having a tissue-penetrating implement in its distal-end region, and elements for delivering a selected agent into a cavity formed by the implement.
摘要:
An adjustable spinal implant (10) is provided for use in connecting elongate members (12) as well as vertebral spacers such as corpectomy devices, intervertebral fusion devices, and other prostheses. The implant (10) may have fittings (80) on either end comprising fixed (100) or articulating (200) jaws, endplates, or other engagement structures. The implant (10) comprises a housing (40) with an internal rotor (60); an extending shaft (20); and a locking collar (70). The extending shaft (20) has an external helical groove (23) that meshes with an internal helical groove (63) on rotor (20). Length adjustment occurs by transforming axial movement of the extending shaft (20) into a rotary movement of the rotor (60) via helical engagement. The locking collar (70) comprises protrusion (73) engaging grooves (63) of rotor (60), thus providing a simple, positive locking mechanism without requiring the surgeon to apply excessive force to lock the length.
摘要:
Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.
摘要:
An adjustable spinal implant 10 is provided for use in connecting elongate members 12 as well as in vertebral spacers such as corpectomy devices, intervertebral fusion devices, and other prostheses. The implant 10 may have fittings 80 on either end comprising fixed 100 or articulating jaws 200, endplates, or other engagement structures. The implant 10 comprises a housing 40 with an internal rotor 60; an extending shaft 20; and a locking collar 70. The extending shaft 20 has an external helical groove 23 that meshes with an internal helical groove 63 on the rotor 20. Length adjustment occurs by transforming axial movement of the extending shaft 20 into a rotary movement of the rotor 60 via helical engagement. The locking collar 70 comprises protrusion 73 engaging grooves 63 of rotor 60, thus providing a simple, positive locking mechanism without requiring the surgeon to apply excessive force to lock the length.