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公开(公告)号:US20050272890A1
公开(公告)日:2005-12-08
申请号:US11143384
申请日:2005-06-02
申请人: Tatsuya Konishi , Takeo Matsumura , Kenjiro Mori
发明人: Tatsuya Konishi , Takeo Matsumura , Kenjiro Mori
IPC分类号: C08F2/20 , C08F12/00 , C08F112/08 , C08F112/36 , C08F212/08 , C08F212/36 , C08F20/44
CPC分类号: C08F2/20 , C08F112/08 , C08F112/36 , Y10S526/909 , C08F2/44
摘要: The present invention provides a method of producing porous spherical particles, which includes suspension polymerization of a multifunctional monomer having two or more vinyl groups and a vinyl monomer having one vinyl group in an aqueous medium in the presence of a porogen and a distribution stabilizer, wherein the distribution stabilizer is polyvinyl alcohol having a saponification degree of 75 to 85 mol %. According to the method of the present invention, generation of particle agglomerates and large particles can be suppressed and porous spherical particles having a desired average particle size and a narrow particle size distribution can be conveniently produced.
摘要翻译: 本发明提供一种制造多孔球形颗粒的方法,其包括在致孔剂和分布稳定剂的存在下,在含水介质中具有两个或多个乙烯基的多官能单体和具有一个乙烯基的乙烯基单体的悬浮聚合,其中 分散稳定剂是皂化度为75〜85摩尔%的聚乙烯醇。 根据本发明的方法,可以抑制颗粒附聚物和大颗粒的产生,并且可以方便地制备具有期望的平均粒度和窄的粒度分布的多孔球形颗粒。
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公开(公告)号:US06391652B2
公开(公告)日:2002-05-21
申请号:US09120192
申请日:1998-07-22
申请人: Keisaku Okada , Kenjiro Mori , Shuji Senda
发明人: Keisaku Okada , Kenjiro Mori , Shuji Senda
IPC分类号: G01N3353
CPC分类号: G01N33/558 , Y10S436/81
摘要: An immunoassay method comprising bringing an immobilized phase comprising, at different positions on a water-absorbable base material, at least two first immunity substances capable of specifically binding with at least two kinds of assay target substances selected from the group consisting of verotoxin-producing Escherichia coli, verotoxin and human hemoglobin contained in a test sample, into contact with a test sample and a liquid containing labeled immunity substances each comprising a second immunity substance that is labeled with colored particles and capable of binding with said assay target substance, thereby to form an assay target substance-labeled immunity substance complex and to bind said complex with respective first immunity substances at the immobilized phase. The immunoassay method, the immunoassay device and the immunoassay kit of the present invention enable easy and simultaneous analysis of O157 (VTEC), VT and Hb in a test sample, by adsorption of the assay target substances on an immobilized phase and evaluation of the developed color.
摘要翻译: 一种免疫测定方法,其特征在于,使含有能够吸水性基材的不同位置的固定相含有至少两种能够与选自产生毒力素的大肠杆菌的至少两种检测对象物质特异性结合的第一免疫物质 包含在测试样品中的大肠杆菌,藜芦毒素和人血红蛋白与测试样品和含有标记免疫物质的液体接触,每个液体包含用有色颗粒标记并能够与所述测定目标物质结合的第二免疫物质,从而形成 测定目标物质标记的免疫物质复合物,并在固定化阶段将所述复合物与各自的第一免疫物质结合。 本发明的免疫测定方法,免疫测定装置和免疫测定试剂盒能够容易地并同时分析试验样品中的O157(VTEC),VT和Hb,通过将测定目标物质吸附在固定相上, 颜色。
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公开(公告)号:US08669356B2
公开(公告)日:2014-03-11
申请号:US12908676
申请日:2010-10-20
申请人: Yoshihiro Hayakawa , Masaki Tsukamoto , Kenjiro Mori , Kenjiro Minomi , Eri Maeta , Tatsuya Konishi
发明人: Yoshihiro Hayakawa , Masaki Tsukamoto , Kenjiro Mori , Kenjiro Minomi , Eri Maeta , Tatsuya Konishi
CPC分类号: C07H21/04 , C07B2200/11 , C07C69/40 , C40B80/00 , Y02P20/55
摘要: The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae wherein each symbol is as defined in the specification.
摘要翻译: 本发明提供能够合成在3'末端具有磷酸基团的核酸的通用接头,携带接头的通用载体,以及使用通用载体的核酸的合成方法。 用于固相合成核酸的接头包含由至少一个下式表示的化合物,其中每个符号如说明书中所定义。
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34.
公开(公告)号:US08592542B2
公开(公告)日:2013-11-26
申请号:US12490444
申请日:2009-06-24
申请人: Kenjiro Mori , Eri Maeta , Tatsuya Konishi
发明人: Kenjiro Mori , Eri Maeta , Tatsuya Konishi
CPC分类号: C08F8/12 , C08F12/22 , C08F12/24 , C08F212/08 , C08F2800/10 , C08F220/58 , C08F212/36 , C08F212/14 , C08F220/56
摘要: The present invention provides porous resin beads containing an aromatic monovinyl compound-divinyl compound-(meth)acrylamide derivative copolymer. Preferably, the copolymer further contains as a structural unit a second aromatic monovinyl compound having a functional group capable of binding to a carboxyl group by a dehydrating condensation reaction.
摘要翻译: 本发明提供了含有芳香族单乙烯基化合物 - 二乙烯基化合物 - (甲基)丙烯酰胺衍生物共聚物的多孔树脂珠粒。 优选地,共聚物还含有具有能够通过脱水缩合反应与羧基结合的官能团的第二芳族单乙烯基化合物作为结构单元。
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公开(公告)号:US08487013B2
公开(公告)日:2013-07-16
申请号:US12265015
申请日:2008-11-05
申请人: Kenjiro Mori , Tatsuya Konishi
发明人: Kenjiro Mori , Tatsuya Konishi
IPC分类号: C08J9/28
CPC分类号: C08F2/20 , C08F212/08 , C08F212/36 , C08F2220/281 , C08F2220/302 , C08F212/14
摘要: The present invention relates to a method for producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, the method including: dissolving a monomer mixture containing an aromatic vinyl compound, an aromatic divinyl compound and a (meth)acrylic acid ester having one hydroxyl group within the molecule thereof, and a polymerization initiator in an organic solvent to obtain a solution containing the monomer mixture and the polymerization initiator; suspending the solution in water in the presence of a dispersion stabilizer; and performing a suspension copolymerization. The method of the invention is capable of easily producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, that is used as a support for solid phase synthesis and enables efficient nucleic acid synthesis.
摘要翻译: 本发明涉及含有具有羟基的芳香族乙烯基化合物 - 芳香族二乙烯基化合物共聚物的多孔性树脂粒子的制造方法,该方法包括:将含有芳族乙烯基化合物,芳族二乙烯基化合物和(甲基) )丙烯酸酯和分子内具有一个羟基的聚合引发剂,得到含有单体混合物和聚合引发剂的溶液; 在分散稳定剂的存在下将溶液悬浮在水中; 并进行悬浮共聚。 本发明的方法能够容易地制备含有具有羟基的芳族乙烯基化合物 - 芳族二乙烯基化合物共聚物的多孔树脂颗粒,其用作固相合成的载体并能够有效地进行核酸合成。
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公开(公告)号:US20050054742A1
公开(公告)日:2005-03-10
申请号:US10928831
申请日:2004-08-27
申请人: Kenjiro Mori , Tatsuya Konishi , Ayako Matsunawa
发明人: Kenjiro Mori , Tatsuya Konishi , Ayako Matsunawa
IPC分类号: C08F2/18 , C08F8/12 , C08F212/14 , C08J9/16 , C08J9/00
CPC分类号: C08J9/16 , C08F8/12 , C08F212/14 , C08J2325/08 , C08F212/08 , C08F212/36
摘要: The present invention provides, as a resin bead which can be developed for use completely different from the use of conventional polystyrene resin beads, a porous resin bead made from a styrene-hydroxystyrene-divinylbenzene copolymer, which contain a hydroxyl group in an amount of 10-1000 μmol/g, and further, a production method of a porous resin bead made from a styrene-hydroxystyrene-divinylbenzene copolymer, which contains suspension copolymerization of a styrene monomer, an acyloxystyrene monomer and a divinylbenzene monomer using an organic solvent (containing at least hydrocarbon and alcohol) and water, followed by hydrolysis reaction.
摘要翻译: 本发明提供作为可以与常规聚苯乙烯树脂珠粒完全不同的开发用树脂珠,由含有羟基的苯乙烯 - 羟基苯乙烯 - 二乙烯基苯共聚物制成的多孔树脂珠粒的量为10 -1000mumol / g,此外,由苯乙烯 - 羟基苯乙烯 - 二乙烯基苯共聚物制成的多孔树脂珠粒的制造方法,其使用有机溶剂(包含苯乙烯 - 羟基苯乙烯 - 二乙烯基苯共聚物)包含苯乙烯单体,酰氧基苯乙烯单体和二乙烯基苯单体的悬浮共聚 最少的烃和醇)和水,然后进行水解反应。
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公开(公告)号:US06753190B1
公开(公告)日:2004-06-22
申请号:US09486640
申请日:2000-02-29
申请人: Keisaku Okada , Takeshi Saika , Shuji Senda , Kenjiro Mori , Ken Sato
发明人: Keisaku Okada , Takeshi Saika , Shuji Senda , Kenjiro Mori , Ken Sato
IPC分类号: G01N35533
CPC分类号: G01N33/558 , G01N33/543 , G01N33/54306 , Y10S436/808
摘要: The present invention relates to an immunological detection method capable of performing detection of an analyte in a test sample, and a kit used therefor. There is provided an immunological detection method for detecting an analyte by using a water-absorbent substrate in which a capture region is positioned in a given region on a surface thereof, the capture region being immobilized with a first immunochemical component capable of specifically binding to the analyte, wherein the detection signal is amplified and a kit used therefor.
摘要翻译: 本发明涉及能够检测测试样品中的分析物的免疫检测方法及其用途。 提供了一种用于通过使用捕获区域位于其表面上的给定区域中的吸水性基底来检测分析物的免疫学检测方法,所述捕获区域被固定有能够特异性结合至所述捕获区域的第一免疫化学成分 分析物,其中检测信号被扩增和用于其的试剂盒。
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公开(公告)号:US06647550B1
公开(公告)日:2003-11-18
申请号:US09492598
申请日:2000-01-27
IPC分类号: B32B900
CPC分类号: A41D7/00 , A41D2400/24 , Y10T442/20
摘要: The present invention relates to a racing swimsuit and provides a racing swimsuit capable of reducing surface friction resistance and frictional resistance of turbulence in water. The present invention can reduce the surface frictional resistance in water by the provision of a water repellent region on the surface of a swimsuit as well as makes it possible to reduce the frictional resistance of turbulence occurred on the surface of the swimsuit of a racer by the formation of a plurality of fine grooves parallel to a body lengthwise direction.
摘要翻译: 本发明涉及赛车游泳衣,并提供能够降低水中湍流的表面摩擦阻力和摩擦阻力的赛车泳衣。本发明可以通过在水的表面上设置防水区域来降低水中的表面摩擦阻力 游泳衣以及能够通过形成平行于身体长度方向的多个细小沟,来降低赛车游泳者的表面上产生的湍流的摩擦阻力。
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公开(公告)号:US4539563A
公开(公告)日:1985-09-03
申请号:US375589
申请日:1982-05-06
申请人: Kazuaki Sako , Kenjiro Mori
发明人: Kazuaki Sako , Kenjiro Mori
CPC分类号: G06F3/0489
摘要: A line drawing method for display apparatus having memory means for storing line information including the start point and end point of any line which has been displayed on the display screen, comprising the steps of entering start point data and a line drawing instruction for a line to be displayed on the display screen, determining the end point of the line to be displayed in accordance with the entered information and stored line information, generating line information based on said determination, storing the generated information in the memory means, and displaying the generated information on the display screen.
摘要翻译: 一种用于显示装置的线条绘制方法,具有存储装置,用于存储包括已经在显示屏幕上显示的任何行的开始点和结束点的行信息,包括以下步骤:将起点数据和行绘制指令输入到 显示在显示屏幕上,根据输入的信息确定要显示的行的结束点和存储的行信息,基于所述确定生成行信息,将生成的信息存储在存储装置中,并显示所生成的信息 在显示屏上。
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40.
公开(公告)号:US08802745B2
公开(公告)日:2014-08-12
申请号:US12883684
申请日:2010-09-16
申请人: Kenjiro Mori , Eri Maeta , Tatsuya Konishi
发明人: Kenjiro Mori , Eri Maeta , Tatsuya Konishi
IPC分类号: C08F8/32 , C08F212/08 , C08F222/30 , C08F212/14 , C08F212/36
CPC分类号: C08F212/08 , C08F8/32 , C08F222/30 , C08F212/14 , C08F212/36
摘要: The present invention relates to a porous resin bead containing a first aromatic monovinyl compound-divinyl compound-(meth)acrylonitrile-second aromatic monovinyl compound copolymer, in which the second aromatic monovinyl compound contains a group capable of binding with a carboxyl group by dehydration condensation reaction, and in which the porous resin bead has a swelling volume in acetonitrile of from 3 to 6 ml/g.
摘要翻译: 本发明涉及含有第一芳族单乙烯基化合物 - 二乙烯基化合物 - (甲基)丙烯腈 - 第二芳族单乙烯基化合物共聚物的多孔树脂珠粒,其中第二芳族单乙烯基化合物含有能够通过脱水缩合与羧基结合的基团 反应,其中多孔树脂珠在乙腈中的溶胀体积为3-6ml / g。
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