公开(公告)号：US20170368109A1

公开(公告)日：2017-12-28

申请号：US15636002

申请日：2017-06-28

申请人： Animal Cell Therapies Inc.

发明人： Kathryn J. Petrucci ,  Sarah E. Royer Köster

IPC分类号： A61K35/742 ,  A61K9/00

CPC分类号： A61K35/742 ,  A61K9/0014 ,  A61K9/0017 ,  A61K9/0046 ,  A61K47/10 ,  A61K47/12 ,  A61K47/16 ,  A61K47/26 ,  A61K47/46 ,  A61K2236/00

摘要： This document relates to materials and methods for treating infections (e.g., ear infections and/or skin infections). For example, methods and materials for using a probiotic fermentation product to treat a veterinary animal (e.g., non-human mammal) having an infection and/or a complication associated with an infection (e.g., hearing loss caused by an ear infection) are provided.

公开(公告)号：US20170360863A1

公开(公告)日：2017-12-21

申请号：US15534089

申请日：2015-12-09

申请人： Academia Sinica

发明人： Ning-Sun YANG ,  Wen-Chi WEI ,  Sheng-Yen LIN ,  Pei-Wen HSIAO ,  Yet-Ren CHEN

IPC分类号： A61K36/28 ,  A61K39/395 ,  C07K16/28 ,  A61K39/00 ,  A61K45/06

CPC分类号： A61K36/28 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  A61K2236/00 ,  C07K16/2803 ,  C07K2317/92

摘要： A pharmacological composition for use in inhibiting differentiation, functional activities, and population of granulo-cytic myeloid-derived suppressor cells (gMDSCs) and/or suppressing, tumor metastasis in a subject in need thereof is disclosed. The composition comprises a therapeutically effective amount of Bidens pilosa extract, or more than one polyacetylenic compounds purified or isolated from the B. pilosa extract, and a pharmaceutically acceptable carrier.

公开(公告)号：US20170354628A1

公开(公告)日：2017-12-14

申请号：US15626125

申请日：2017-06-18

申请人： Kodimule Shyam Prasad ,  Harakanahalli Lingaraju Basavegowda

发明人： Kodimule Shyam Prasad ,  Harakanahalli Lingaraju Basavegowda

IPC分类号： A61K31/216 ,  A61K36/74

CPC分类号： A61K31/216 ,  A61K36/74 ,  A61K2236/00 ,  A61K2300/00

摘要： The present invention is directed compositions derived from green coffee bean extract and methods for the use and manufacture of such compositions. The compositions of the invention have unique ratios of chlorogenic acids which offer a therapeutic effect in the treatment of a variety of conditions and disorders. Methods for using the compositions of the invention include, but not limited to, methods for treating obesity and methods for regulating serum lipids.

公开(公告)号：US20170340689A1

公开(公告)日：2017-11-30

申请号：US15528880

申请日：2015-11-24

申请人： ABOCA S.P.A SOCIETÀ AGRICOLA

发明人： Valentino MERCATI

IPC分类号： A61K36/28 ,  A61K31/216 ,  A61K31/365 ,  A61K31/519

CPC分类号： A61K36/28 ,  A61K31/192 ,  A61K31/216 ,  A61K31/343 ,  A61K31/365 ,  A61K31/519 ,  A61K2236/00 ,  A61K2300/00

摘要： The present invention relates to a titrated extract of Cynara scolymus, to titrated fractions of extract of Cynara scolymus or titrated mixtures of said extract with one or more of said titrated fractions or mixtures of said fractions and to compositions and kits that comprise them for the prevention and/or the treatment of malignant pleural mesothelioma.

公开(公告)号：US09828442B2

公开(公告)日：2017-11-28

申请号：US14855143

申请日：2015-09-15

申请人： Chang Gung Biotechnology Corp.

发明人： Yun-Fei Ko ,  Jan Martel ,  Jian-Ching Liau ,  I-Te Chang ,  Chien-Sheng Lee ,  Wei-Chang Wang ,  Chen-Yaw Chiu ,  Chih-Jung Chang ,  Chuan-Sheng Lin ,  Tsung-Ru Wu ,  Chia-Chen Lu ,  David Marcelo Ojcius ,  Hsin-Chih Lai ,  Ding-E Young

IPC分类号： A61K36/00 ,  C08B37/00 ,  A61K36/062

CPC分类号： C08B37/0003 ,  A61K36/062 ,  A61K2236/00

摘要： The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce hyperglycemia and insulin resistance, and can therefore be used to prevent and treat type 2 diabetes and related conditions.

公开(公告)号：US09765000B2

公开(公告)日：2017-09-19

申请号：US15004848

申请日：2016-01-22

申请人： Phytoplant Research S.L.

发明人： Xavier Nadal Roura

IPC分类号： C07C37/68 ,  A61K36/185 ,  B01D15/26 ,  C07C37/84 ,  C07C39/19 ,  C07C39/23 ,  C07C51/43 ,  C07C65/19

CPC分类号： C07C37/685 ,  A61K36/185 ,  A61K2236/00 ,  B01D15/26 ,  C07C37/84 ,  C07C39/19 ,  C07C39/23 ,  C07C51/43 ,  C07C65/19

摘要： The present specification discloses methods of purifying one or more cannabinoids from a plant material, purified cannabinoids and pharmaceutical compositions comprising one or more cannabinoids produced by the disclosed method, methods and uses for treating a disease or condition employing such purified cannabinoids and pharmaceutical compositions.

公开(公告)号：US09750783B2

公开(公告)日：2017-09-05

申请号：US14198932

申请日：2014-03-06

申请人： National Dong Hua University

发明人： Maw-Kuen Wu ,  Ching-Feng Weng ,  Hung-Yuan Shih ,  Huei-Wun Sie

IPC分类号： A61K36/898 ,  A61K9/00 ,  A61K9/08

CPC分类号： A61K36/898 ,  A61K9/0019 ,  A61K9/08 ,  A61K2236/00

摘要： The present invention is related to a pharmaceutical composition comprising an effective amount of a Spiranthes sinensis extract and a pharmaceutically acceptable carrier. The present invention improves the economic value of Spiranthes sinensis by verifying the efficacies of said pharmaceutical composition in anti-inflammation, anti-liver fibrosis and/or anti-oxidation.

公开(公告)号：US20170224757A1

公开(公告)日：2017-08-10

申请号：US15327875

申请日：2015-07-22

申请人： SIGNUM NUTRALOGIX, INC.

发明人： Kristen Huber ,  Michael Voronkov ,  Jose Fernandez ,  Karl Rouzard ,  Eduardo Perez ,  Maxwell Stock ,  Jeffry Stock

IPC分类号： A61K36/9066 ,  A61K36/736 ,  A61K36/54 ,  A61K36/73 ,  A61K36/45 ,  A61Q19/08 ,  A61K36/33 ,  A61K9/00 ,  A61K8/97 ,  A61K36/23 ,  A61K36/185 ,  A61K36/28 ,  A61K36/235 ,  A61K36/71 ,  A61K36/77 ,  A61K36/14 ,  A61K36/31 ,  A61K36/575 ,  A61K36/79 ,  A61K36/52 ,  A61K36/87

CPC分类号： A61K36/9066 ,  A61K8/97 ,  A61K9/0014 ,  A61K9/0053 ,  A61K36/14 ,  A61K36/185 ,  A61K36/23 ,  A61K36/235 ,  A61K36/28 ,  A61K36/31 ,  A61K36/33 ,  A61K36/45 ,  A61K36/52 ,  A61K36/54 ,  A61K36/575 ,  A61K36/71 ,  A61K36/73 ,  A61K36/736 ,  A61K36/77 ,  A61K36/79 ,  A61K36/87 ,  A61K45/06 ,  A61K2236/00 ,  A61K2236/31 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/39 ,  A61K2236/51 ,  A61K2236/53 ,  A61K2800/5922 ,  A61K2800/782 ,  A61K2800/805 ,  A61K2800/92 ,  A61Q19/08 ,  A61K2300/00

摘要： Compositions containing natural and botanical extracts for use in inhibiting one, two, or three of (a)-(c): (a) demethylation of PP2A by PME-1 methylesterase; (b) formation of free radicals and reactive oxygen species; and/or (c) inflammation. These compositions include an extract of one or more botanicals selected from the group consisting of: juniper berry fruit, schisandra fruit, strawberry fruit, avocado seeds, black raspberry seeds, blueberry seeds, celery seeds, cranberry seeds, fennel seeds, grape seeds, guarana seeds, red raspberry seeds, maca root, goldenseal root, turmeric root, magnolia bark, pygeum bark, red raspberry leaf, almond, cocoa powder, Echinacea angustifolia, prickly pear cactus and walnut.

公开(公告)号：US20170190728A1

公开(公告)日：2017-07-06

申请号：US15425295

申请日：2017-02-06

申请人： PureCircle Sdn Bhd

发明人： Avetik MARKOSYAN

IPC分类号： C07H15/256 ,  A21D2/18 ,  A23C9/13 ,  A23G1/40 ,  B01D15/42 ,  A23G9/34 ,  A23L2/02 ,  A23L2/60 ,  A23L27/50 ,  B01D15/18 ,  C07H1/08 ,  A23G3/42

CPC分类号： C07H15/256 ,  A21D2/181 ,  A23C9/1307 ,  A23G1/40 ,  A23G3/42 ,  A23G9/34 ,  A23L2/02 ,  A23L2/60 ,  A23L27/36 ,  A23L27/50 ,  A23V2002/00 ,  A61K8/602 ,  A61K31/7034 ,  A61K31/704 ,  A61K36/28 ,  A61K2236/00 ,  A61Q11/00 ,  B01D15/1871 ,  B01D15/1885 ,  B01D15/426 ,  C07H1/06 ,  C07H1/08

摘要： Methods of preparing highly purified steviol glycosides, particularly Rebaudioside D, are described. The methods include purification from the extraction stage of the Stevia rebaudiana Bertoni plant, purification of steviol glycoside mixtures, Rebaudioside D and Rebaudioside A from a commercial Stevia extract, and purification of Rebaudioside D from remaining solutions obtained after isolation and purification of Rebaudioside A and a high purity mixture of steviol glycosides. The methods are useful for producing high purity Rebaudioside D, Rebaudioside A, and steviol glycoside mixtures. The high purity steviol glycosides are useful as non-caloric sweeteners in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

公开(公告)号：US09694044B2

公开(公告)日：2017-07-04

申请号：US14492221

申请日：2014-09-22

申请人： GLOBAL NUTRITECH BIOTECHNOLOGY LLC

发明人： Veysel Akay

IPC分类号： A61K36/889 ,  A61K36/49 ,  A61K36/52

CPC分类号： A61K36/49 ,  A61K2236/00

摘要： Compositions comprising thermo-modified nutshells, for example hazelnut shells, are described herein. The compositions can also comprise one or more feed additives, pharmaceutically acceptable diluents and/or excipients. Also included are methods for producing the thermo-modified nutshell compositions, and methods for using the compositions to treat diarrhea and adsorb toxins as well as promote growth and improve the overall health in humans and other animals.