公开(公告)号：US20220346411A1

公开(公告)日：2022-11-03

申请号：US17865745

申请日：2022-07-15

申请人： PURECIRCLE SDN BHD

发明人： Avetik MARKOSYAN

IPC分类号： A23L2/60 ,  C07J17/00 ,  A61K8/63 ,  A23L27/30 ,  A61K8/97

摘要： The present invention provides a process for preparation of highly purified mogrosides mixture from low purity mogrosides mixture. The process comprises providing a mixture of low purity mogrosides, dissolving the low purity mogrosides mixture in water or an aqueous alcohol solution to form an initial solution of mogrosides, passing the initial solution through a column system, wherein the column system comprises a plurality of columns, and each column is packed with a sorbent having different affinities to impurities and mogrosides so that one or more columns retains more mogrosides than other columns, washing the columns to remove impurities with an acidic aqueous solution, a basic aqueous solution, and an aqueous alcoholic solution successively, eluting the columns with an aqueous alcohol solution that contains higher alcohol content than the aqueous alcohol solution used in the washing step, wherein the eluate from the columns with high content of mogrosides are combined, and drying the combined eluate to obtain high purity mogrosides with the content of the total mogrosides are more than 70% (w/w). The present invention also provides a sweetener mixture and product comprising high purity mogrosides.

公开(公告)号：US20190150493A1

公开(公告)日：2019-05-23

申请号：US16255614

申请日：2019-01-23

申请人： PureCircle Sdn Bhd

发明人： Avetik MARKOSYAN

IPC分类号： A23L27/30 ,  A61Q19/00 ,  A23L2/60 ,  A61K36/28 ,  A61K8/60 ,  A61Q11/00 ,  A61K8/97 ,  C12P33/00 ,  C12P19/56 ,  C12P19/18 ,  A23C9/13 ,  A21D2/36 ,  A21D2/18

摘要： Glucosyl stevia compositions are prepared from steviol glycosides of Stevia rebaudiana Bertoni. The glucosylation was performed by cyclodextrin glucanotransferase using the starch as source of glucose residues. The short-chain glucosyl stevia compositions were purified to >95% content of total steviol glycosides. The compositions can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20180146700A1

公开(公告)日：2018-05-31

申请号：US15882532

申请日：2018-01-29

申请人： PureCircle Sdn Bhd

发明人： Avetik MARKOSYAN

IPC分类号： A23L2/60 ,  C07H15/256 ,  A23L27/00 ,  A23L27/30

CPC分类号： A23L2/60 ,  A23L27/33 ,  A23L27/88 ,  C07H15/256

摘要： Stevia compositions are prepared from steviol glycosides of Stevia rebaudiana Bertoni. The compositions are able to provide a superior taste profile and can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20170196247A1

公开(公告)日：2017-07-13

申请号：US15470388

申请日：2017-03-27

申请人： PureCircle Sdn Bhd

发明人： Avetik MARKOSYAN

IPC分类号： A23L27/30 ,  C12P19/56 ,  A23C9/13 ,  A23L2/56 ,  A21D13/80 ,  A23L27/00

CPC分类号： A23L27/35 ,  A21D2/18 ,  A21D2/36 ,  A21D13/80 ,  A23C9/1307 ,  A23L2/02 ,  A23L2/54 ,  A23L2/56 ,  A23L2/60 ,  A23L27/33 ,  A23L27/36 ,  A23L27/88 ,  A23V2002/00 ,  A61K36/28 ,  C12P19/14 ,  C12P19/18 ,  C12P19/56 ,  C12Y204/01019 ,  C12Y302/01001 ,  Y02P20/52

摘要： Glucosyl stevia compositions are prepared from steviol glycosides of Stevia rebaudiana Bertoni. The glucosylation was performed by cyclodextrin glucanotransferase using the starch as source of glucose residues. The glucosyl stevia compositions were purified to >95% content of total steviol glycosides. The compositions can be used as sweetness enhancers, flavors, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20170020176A1

公开(公告)日：2017-01-26

申请号：US15284265

申请日：2016-10-03

申请人： PureCircle Sdn Bhd

发明人： Avetik MARKOSYAN ,  Siddhartha PURKAYASTHA

IPC分类号： A23L27/30 ,  A61K47/26 ,  C07H15/24 ,  A61K8/60 ,  A23L2/60 ,  A24B15/40

CPC分类号： A23L27/34 ,  A23L2/60 ,  A23L27/33 ,  A23L27/36 ,  A23V2002/00 ,  A24B13/00 ,  A24B15/403 ,  A61K8/602 ,  A61K47/26 ,  A61K2800/10 ,  A61Q11/00 ,  A61Q19/00 ,  C07H1/08 ,  C07H15/24

摘要： The invention relates to a process for producing highly soluble compositions containing purified steviol glycosides from Stevia rebaudiana Bertoni plant extract, more particularly Rebaudioside D. Obtained highly soluble compositions are useful as non-caloric sweeteners or in combination with sugar or high intensity sweeteners in edible and chewable compositions such as beverages, confectionaries, bakery products, chewing gums and the like.

摘要翻译： 本发明涉及一种用于生产含有甜叶菊甜叶菊植物提取物，特别是甜菜苷D的纯化甜菊糖苷的高度可溶性组合物的方法。获得的高溶解性组合物可用作非热量甜味剂，或与糖或高强度甜味剂在食用和/ 咀嚼成分如饮料，糖果，面包店产品，口香糖等。

公开(公告)号：US20220162249A1

公开(公告)日：2022-05-26

申请号：US17464913

申请日：2021-09-02

申请人： PURECIRCLE SDN BHD

发明人： Avetik MARKOSYAN

IPC分类号： C07H15/256 ,  A61K31/704 ,  B01D15/18 ,  A61K8/60 ,  A23L2/02 ,  C07H1/06 ,  A23L27/50 ,  A23G3/42 ,  A61K31/7034 ,  A61K36/28 ,  B01D15/42 ,  A21D2/18 ,  A23L2/60 ,  A61Q11/00 ,  A23L27/30 ,  A23C9/13 ,  A23G1/40 ,  A23G9/34 ,  C07H1/08

摘要： Methods of preparing highly purified steviol glycosides, particularly Rebaudioside D, are described. The methods include purification from the extraction stage of the Stevia rebaudiana Bertoni plant, purification of steviol glycoside mixtures, Rebaudioside D and Rebaudioside A from a commercial Stevia extract, and purification of Rebaudioside D from remaining solutions obtained after isolation and purification of Rebaudioside A and a high purity mixture of steviol glycosides. The methods are useful for producing high purity Rebaudioside D, Rebaudioside A, and steviol glycoside mixtures. The high purity steviol glycosides are useful as non-caloric sweeteners in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

公开(公告)号：US20220125084A1

公开(公告)日：2022-04-28

申请号：US17572094

申请日：2022-01-10

申请人： PURECIRCLE SDN BHD

发明人： Avetik MARKOSYAN

IPC分类号： A23L27/30 ,  A23L27/00 ,  A23L27/10 ,  A23L27/12 ,  A23L33/21 ,  A23G3/36 ,  A23G9/32 ,  A23L2/60 ,  A61K8/60 ,  A61Q19/00 ,  A61K36/28 ,  A61K8/9789

摘要： Stevia compositions are prepared from steviol glycosides of Stevia rebaudiana Bertoni. The compositions are able to provide a superior taste profile and can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20210002319A1

公开(公告)日：2021-01-07

申请号：US17026298

申请日：2020-09-21

申请人： PureCircle Sdn Bhd

发明人： Avetik MARKOSYAN

IPC分类号： C07H15/24 ,  A61K8/60 ,  A61Q19/00 ,  A23L2/60 ,  C07H1/00 ,  A61K36/28 ,  A23L27/30 ,  A23L33/10 ,  A61K47/26 ,  C07H1/06

摘要： Various ingredients and compositions are prepared from Stevia rebaudiana Bertoni plant. The compositions can be used as bulking agents, and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20200253255A1

公开(公告)日：2020-08-13

申请号：US16793813

申请日：2020-02-18

申请人： PureCircle Sdn Bhd

发明人： Siddhartha PURKAYASTHA ,  Avetik MARKOSYAN ,  John MARTIN ,  Marcia PETIT

IPC分类号： A23L27/30 ,  A23C9/13 ,  A23C9/156 ,  A23F3/40 ,  A23L2/60

摘要： Stevia compositions are prepared from steviol glycosides of Stevia Rebaudiana Bertoni. The compositions are able to provide a superior taste profile and can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20190380368A1

公开(公告)日：2019-12-19

申请号：US16553975

申请日：2019-08-28

申请人： PureCircle Sdn Bhd

发明人： Siddhartha PURKAYASTHA ,  Avetik MARKOSYAN

IPC分类号： A23L27/30 ,  A23L2/60 ,  A23L27/00

摘要： A taste and flavor profile modifying composition is described. The composition includes a blend of glucosylated steviol glycosides and residual steviol glycosides which can modify the intensity of a taste and/or flavor in a food or beverage product.