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    AUTOMATIC ANALYZER AND DISPENSING METHOD THEREOF
    32.
    发明申请
    AUTOMATIC ANALYZER AND DISPENSING METHOD THEREOF 有权
    自动分析仪及其分配方法

    公开(公告)号：US20090169432A1

    公开(公告)日：2009-07-02

    申请号：US12345112

    申请日：2008-12-29

    申请人： Akihisa KURODA

    发明人： Akihisa KURODA

    IPC分类号： G01N21/01 ,  G01F11/10

    CPC分类号： G01N35/1009 ,  Y10T436/114998 ,  Y10T436/115831 ,  Y10T436/12

    摘要： Provided are an automatic analyzer which moves a dispensing apparatus having a dispensing probe, or a vessel by a driving mechanism to dispense plural liquids into the vessel via the dispensing probe, and measures and analyzes optical characteristic of a reaction liquid in which each of the dispensed liquids is reacted, and a dispensing method thereof. The automatic analyzer includes a drive controlling unit which controls the driving mechanism so that the liquid surface of the liquid and a distal end of the dispensing probe are moved relatively to each other in a vertical direction, and, when the liquids including precipitated substance are to be dispensed, the dispensing probe sucks in the liquids from plural different positions along the vertical direction.

    摘要翻译： 提供了一种自动分析器，其通过驱动机构移动具有分配探针的分配装置或容器，以通过分配探针将多个液体分配到容器中，并且测量和分析反应液体的光学特性，其中每个分配 液体反应，并且其分配方法。 所述自动分析装置具有：驱动控制部，其控制所述驱动机构，使得所述液体的液面与所述分注用探针的前端在上下方向相对移动，并且，当所述液体包含析出物质为 分配探针沿垂直方向从多个不同位置吸入液体。

    Method and Apparatus for Stripping a Contact-Limiting Element from a Pipette Probe
    34.
    发明申请
    Method and Apparatus for Stripping a Contact-Limiting Element from a Pipette Probe 有权
    用于从移液管探针剥离接触限制元件的方法和装置

    公开(公告)号：US20090095091A1

    公开(公告)日：2009-04-16

    申请号：US12335812

    申请日：2008-12-16

    申请人： Robert J. Smith

    发明人： Robert J. Smith

    IPC分类号： B01L3/02

    CPC分类号： C12Q1/6834 ,  B01F9/0001 ,  B01F9/0014 ,  B01F9/0021 ,  B01F2009/0074 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/06 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  B03C1/282 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/26 ,  C12Q1/6813 ,  C12Q1/6832 ,  C12Q2537/10 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T29/53657 ,  Y10T29/53683 ,  Y10T29/53843 ,  Y10T156/1105 ,  Y10T156/1906 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

    摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站，在规定温度下培养样品规定的时间，进行分析物分离程序，并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

    Method and device for test sample loading
    35.
    发明申请
    Method and device for test sample loading 有权
    测试样品加载的方法和装置

    公开(公告)号：US20090035866A1

    公开(公告)日：2009-02-05

    申请号：US11540227

    申请日：2006-09-29

    申请人： Brian D. Wilson

    发明人： Brian D. Wilson

    IPC分类号： G01N35/00

    CPC分类号： G01N35/0099 ,  G01N35/1083 ,  G01N2035/00277 ,  G01N2035/1032 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/114998 ,  Y10T436/2575

    摘要： An automated analyzer is configured to receive and analyze samples provided to the automated analyzer in primary sample containers. The automated analyzer comprises a sample retention unit, at least one transport device, and at least one aspiration device. The sample retention unit is configured to receive and retain a plurality of sample retention vessels. The sample retention unit may comprise a sample storage unit, an analytic unit, or other processing unit within the automated analyzer that retains a sample for some purpose. The transport device is configured to receive a first primary sample container containing a first sample and deliver the first primary sample container to the sample retention unit as one of the plurality of sample retention vessels. The aspiration device is configured to receive a second sample from a second primary sample container and deliver the second sample into one of the plurality of sample retention vessels.

    摘要翻译： 自动分析仪被配置为接收和分析提供给初级样品容器中的自动分析仪的样品。 所述自动分析器包括样品保持单元，至少一个输送装置和至少一个抽吸装置。 样品保留单元构造成容纳和保留多个样品保留容器。 样品保留单元可以包括在自动分析器内的样品存储单元，分析单元或其他处理单元，其保留用于某些目的的样品。 输送装置构造成接收容纳第一样品的第一初级样品容器，并将第一初级样品容器作为多个样品保留容器之一递送到样品保持单元。 抽吸装置被配置为从第二初级样品容器接收第二样品并将第二样品输送到多个样品保留容器中的一个。

    Micro plate treating device and micro plate carrying method
    36.
    发明授权
    Micro plate treating device and micro plate carrying method 有权
    微板处理装置和微板承载方法

    公开(公告)号：US07485465B2

    公开(公告)日：2009-02-03

    申请号：US10549149

    申请日：2005-04-05

    申请人： Akira Higuchi ,  Eiji Watanabe

    发明人： Akira Higuchi ,  Eiji Watanabe

    IPC分类号： G01N35/02 ,  G01N35/04

    CPC分类号： G01N35/028 ,  G01N2035/0405 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/114998

    摘要： In a microplate processing apparatus that removes lid (11) of microplate (10) conveyed by microplate conveying mechanism (3) to perform a dispensing process by dispensing head (8), and that attaches lid (11) after the dispensing process is completed, lid (11) removed by lid removing mechanism (6) at first position (P1) is conveyed to third position (P3) located downstream, by microplate conveying mechanism (3), to be held by lid attaching mechanism (9), and then lid (11) is attached to microplate (10) having been conveyed to third position (P3), after the dispensing process is completed, while microplate (10) with this lid (11) having been attached is being lifted to processing position (P4) above microplate conveying mechanism (3), by microplate stage (12).

    摘要翻译： 在微孔板处理装置中，除去由微孔板输送机构（3）输送的微板（10）的盖（11），以通过分配头（8）进行分配处理，并且在分配过程完成之后附着盖（11） 通过盖板拆卸机构（6）在第一位置（P1）移除的盖子（11）通过微孔板输送机构（3）输送到位于下游的第三位置（P3），由盖子安装机构（9）保持，然后 在分配过程完成之后，将具有已经被附接的盖子（11）的微孔板（10）提升到处理位置（P4），将盖子（11）连接到已经被输送到第三位置（P3）的微孔板（10） ）微孔板输送机构（3），微板台（12）。

    Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer
    38.
    发明授权
    Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer 有权
    多个环组件，用于在自动分析仪内将反应容器提供样品

    公开(公告)号：US07384600B2

    公开(公告)日：2008-06-10

    申请号：US10268899

    申请日：2002-10-11

    申请人： Ralph E. Burns ,  Ernest V. Hansberry

    发明人： Ralph E. Burns ,  Ernest V. Hansberry

    IPC分类号： G01N21/13

    CPC分类号： C12Q1/6834 ,  B01F9/0001 ,  B01F9/0014 ,  B01F9/0021 ,  B01F2009/0074 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/06 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  B03C1/282 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/26 ,  C12Q1/6813 ,  C12Q1/6832 ,  C12Q2537/10 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T29/53657 ,  Y10T29/53683 ,  Y10T29/53843 ,  Y10T156/1105 ,  Y10T156/1906 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

    摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，预处理分析物分离程序以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。