公开(公告)号：US20210325311A1

公开(公告)日：2021-10-21

申请号：US17272527

申请日：2019-08-29

Applicant: Aaron Kurt Neumann ,  Anatoliy O. Pinchuk ,  STC.UNM

Inventor： Aaron Kurt NEUMANN ,  Anatoliy O PINCHUK

IPC: G01N21/65 ,  G01J3/44

Abstract: Highly sensitive assays for pathogen detection, identification and/or analysis including, but not limited to, sensing of metabolite patterns associated with high-risk drug resistance phenotypes.

公开(公告)号：US11095461B2

公开(公告)日：2021-08-17

申请号：US16346772

申请日：2017-11-03

Applicant: STC.UNM

Inventor： James Plusquellic ,  Wenjie Che

IPC: H04L29/06 ,  H04L9/32 ,  G06F21/44 ,  G09C1/00 ,  G06F17/10

Abstract: The Distribution Effect is proposed for the HELP PUF that is based on purposely introducing biases in the mean and range parameters of path delay distributions to enhance entropy. The biased distributions are then used in the bitstring construction process to introduce differences in the bit values associated with path delays that would normally remain fixed. Offsets are computed to fine tune a token's digitized path delays as a means of maximizing entropy and reproducibility in the generated bitstrings: a first population-based offset method computes median values using data from multiple tokens (i.e., the population) and a second chip-specific technique is proposed which fine tunes path delays using enrollment data from the authenticating token.

公开(公告)号：US11086028B2

公开(公告)日：2021-08-10

申请号：US16785932

申请日：2020-02-10

Applicant: National Technology & Engineering Solutions of Sandia, LLC ,  STC.UNM

Inventor： Timothy J. Boyle ,  Fernando Henry Garzon

IPC: G01T1/10 ,  G01T1/204 ,  G01T1/105

Abstract: A low cost, rapid, flexible radiation detector uses inorganic metal halide precursors and dyes that respond to self-quenching hybrid scintillation. Remote, high-contrast, laser sensing can be used to determine when exposure of the detector to radiation occurs (even temporally).

公开(公告)号：US20210154968A1

公开(公告)日：2021-05-27

申请号：US16954164

申请日：2018-12-14

Applicant: STC.UNM

Inventor： Eslam Mohamed Soliman ,  Mahmoud Reda Taha

IPC: B32B5/08 ,  B32B5/26

Abstract: A 3D printed fiber reinforced polymer composite having a nonlinear stress-strain profile created by a central layer and a plurality of recruited successive layers.

公开(公告)号：US10988533B2

公开(公告)日：2021-04-27

申请号：US15548871

申请日：2016-02-05

Applicant: STC.UNM ,  Bridget S. Wilson ,  Stuart S. Winter ,  Michael Frank Erasmus ,  Michael Horowitz

Inventor： Bridget S. Wilson ,  Stuart S. Winter ,  Michael Frank Erasmus ,  Michael Horowitz

IPC: A61K39/395 ,  C07K16/28 ,  A61P35/02

Abstract: This disclosure describes the identification of pre-B Cell Receptor (pre-BCR) antagonists and the use of pre-BCR antagonists as a targeted therapy. The compositions and methods generally involve a composition that includes a pre-B cell receptor (pre-BCR) antagonist and is engineered for expression as a T cell chimeric receptor. In some embodiments, the pre-BCR antagonists can include an anti-pre-BCR antibody.

公开(公告)号：US10900902B2

公开(公告)日：2021-01-26

申请号：US15568029

申请日：2016-04-20

Applicant: STC.UNM

Inventor： Andrew P Shreve ,  Steven Wayde Graves ,  Bruce S Edwards ,  Jaime Javier Juarez

IPC: G01N21/64 ,  G01J3/02 ,  G01N15/14 ,  G01J3/28 ,  G01N15/02 ,  G01N15/10

Abstract: A method to simultaneously detect emission intensity or images at multiple distinct emission wavelengths in the analysis of parallel sample streams in a flow-based analysis system and apparatus for performing the described method.

公开(公告)号：US10702664B2

公开(公告)日：2020-07-07

申请号：US15676705

申请日：2017-08-14

Applicant: STC.UNM

Inventor： Nicola Jeanne Maynard ,  Hugh D. C. Smyth

IPC: A61M15/00 ,  A61M11/00 ,  A61M16/00

Abstract: A dry powder delivery device may be configured to provide micronized dry powder particles to airways of a user. The device may include a cylindrical container delimiting a chamber containing at least one magnetically-responsive object, a motor external to said chamber, a magnet external to the chamber and rotatably coupled with the motor, and an outflow member configured to direct airflow to a user. The magnetically-responsive object may be coated with micronized dry powder particles, and the motor may be operable to rotate the magnet about an axis. Rotation of the magnet creates a magnetic field that causes the magnetically-responsive object to move in response to the magnetic field and collide with a side wall of the container to deaggregate the dry powder particles and aerosolize the dry powder in the chamber.

公开(公告)号：US10605705B2

公开(公告)日：2020-03-31

申请号：US15950979

申请日：2018-04-11

Applicant: National Technology & Engineering Solutions of Sandia, LLC ,  STC.UNM

Inventor： Bryan J. Kaehr ,  C. Jeffrey Brinker ,  Jason L. Townson

IPC: G01N1/28 ,  C08K3/36 ,  C12N11/14

Abstract: The present invention is directed to the use of silicic acid to transform biological materials, including cellular architecture into inorganic materials to provide biocomposites (nanomaterials) with stabilized structure and function. In the present invention, there has been discovered a means to stabilize the structure and function of biological materials, including cells, biomolecules, peptides, proteins (especially including enzymes), lipids, lipid vesicles, polysaccharides, cytoskeletal filaments, tissue and organs with silicic acid such that these materials may be used as biocomposites. In many instances, these materials retain their original biological activity and may be used in harsh conditions which would otherwise destroy the integrity of the biological material. In certain instances, these biomaterials may be storage stable for long periods of time and reconstituted after storage to return the biological material back to its original form. In addition, by exposing an entire cell to form CSCs, the CSCs may function to provide a unique system to study enzymes or a cascade of enzymes which are otherwise unavailable.

公开(公告)号：US10453996B2

公开(公告)日：2019-10-22

申请号：US15374547

申请日：2016-12-09

Applicant: STC.UNM

Inventor： Steven R. J. Brueck ,  Seung-Chang Lee ,  Christian Wetzel ,  Mark Durniak

IPC: H01L29/778 ,  H01L33/32 ,  H01L21/02 ,  H01L21/78 ,  H01L33/00 ,  H01L33/04 ,  H01L33/18 ,  H01L29/04

Abstract: A method of forming a semiconductor structure includes providing a substrate comprising a first material portion and a single crystal silicon layer on the first material portion. The substrate further comprises a major front surface, a major backside surface opposing the major front surface, and a plurality of grooves positioned in the major front surface. A buffer layer is deposited in one or more of the plurality of grooves. A semiconductor material is epitaxially grown over the buffer layer and in the one or more plurality of grooves, the epitaxially grown semiconductor material comprising a hexagonal crystalline phase layer and a cubic crystalline phase structure disposed over the hexagonal crystalline phase.

公开(公告)号：US20190298222A1

公开(公告)日：2019-10-03

申请号：US16467275

申请日：2017-12-07

Applicant: STC.UNM

Inventor： Sang M. HAN ,  Jarred Caldwell ,  Nicholas BRECHTEL ,  Nathan MADRID ,  Divya PRAKASH

IPC: A61B5/06 ,  A61B5/00 ,  A61J15/00

Abstract: An apparatus for determining a position of an object inside a body includes a first detector configured to receive a signal from the object inside the body. The apparatus also includes a camera configured to capture an image or video of outside of a portion of the body. The object is positioned inside the portion of the body. A connoting system is configured to receive the signal from the first detector and the image or video from the camera and to determine the position of the object inside the body. A screen is configured to display die position of the object inside the body.