公开(公告)号：US20160036061A1

公开(公告)日：2016-02-04

申请号：US14776777

申请日：2014-03-17

Applicant: Plamen B Atanassov ,  Claudia W Narvaez Villarrubia ,  Sergio Omar Garcia

Inventor： Plamen B Atanassov ,  Claudia W Narvaez Villarrubia ,  Sergio Omar Garcia

IPC: H01M4/90 ,  C12P19/36 ,  C01B31/02 ,  C07H19/207

CPC classification number: H01M4/9008 ,  C01B32/168 ,  C01B2202/06 ,  C07H19/207 ,  C12N11/02 ,  C12N11/06 ,  C12P19/36 ,  H01M4/90 ,  H01M8/16 ,  H01M2004/8684 ,  Y02E60/527

Abstract: A family of customizable tethering molecules for tethering cofactors such as, but not necessarily limited to, nicotinamine adenine dinucleotide (NAD+/NADH, NAD(P)+/NAD(P)H) to substrates or structures formed from or including graphene-like materials is described. The tethered cofactor can then be used, for example, as biosensors employed for clinical diagnostic, food industry, medical drug development and environmental and military applications, as well as in reagentless biofuel cells for power generation.

Abstract translation: 用于结合辅因子（例如但不一定限于烟酰胺腺嘌呤二核苷酸（NAD + / NADH，NAD（P）+ / NAD（P）H）的可定制的束缚分子的家族与由石墨烯样材料形成或包括 被描述。 然后可以使用系留辅助因子，例如用作临床诊断，食品工业，医药开发和环境和军事应用的生物传感器，以及用于发电的无试剂生物燃料电池。

公开(公告)号：US09249333B2

公开(公告)日：2016-02-02

申请号：US14157918

申请日：2014-01-17

Applicant: David J. Kissel ,  Charles Jeffrey Brinker

Inventor： David J. Kissel ,  Charles Jeffrey Brinker

IPC: C09D133/12 ,  C09D5/14 ,  C09D5/16 ,  C09D7/12 ,  A01N55/00 ,  C09D5/00 ,  C08K3/36 ,  C08K9/06

CPC classification number: C09D7/1225 ,  A01N55/00 ,  C08K3/36 ,  C08K9/06 ,  C09D5/006 ,  C09D5/14 ,  C09D5/165 ,  C09D5/1681 ,  C09D7/62 ,  C09D133/12 ,  D06N3/0043 ,  D06N3/0063 ,  D10B2401/10 ,  D10B2401/13 ,  Y10T428/249953 ,  Y10T428/249972 ,  Y10T428/24999 ,  Y10T428/249991 ,  Y10T442/20

Abstract: Provided are polymer-aerogel composite coatings, devices and articles including polymer-aerogel composite coatings, and methods for preparing the polymer-aerogel composite. The exemplary article can include a surface, wherein the surface includes at least one region and a polymer-aerogel composite coating disposed over the at least one region, wherein the polymer-aerogel composite coating has a water contact angle of at least about 140° and a contact angle hysteresis of less than about 1°. The polymer-aerogel composite coating can include a polymer and an ultra high water content catalyzed polysilicate aerogel, the polysilicate aerogel including a three dimensional network of silica particles having surface functional groups derivatized with a silylating agent and a plurality of pores.

Abstract translation: 提供聚合物 - 气凝胶复合涂层，装置和制品，包括聚合物 - 气凝胶复合涂层，以及制备聚合物 - 气凝胶复合材料的方法。 示例性制品可以包括表面，其中表面包括至少一个区域和设置在至少一个区域上的聚合物 - 气凝胶复合涂层，其中聚合物 - 气凝胶复合涂层具有至少约140°的水接触角和 接触角滞后小于约1°。 聚合物 - 气凝胶复合涂层可以包括聚合物和超高含水量催化的聚硅酸盐气凝胶，所述聚硅酸盐气凝胶包括具有由甲硅烷基化剂衍生的表面官能团和多个孔的二氧化硅颗粒的三维网络。

公开(公告)号：US09246031B1

公开(公告)日：2016-01-26

申请号：US14471124

申请日：2014-08-28

Applicant: Sang Eon Han ,  Samuel Clark

Inventor： Sang Eon Han ,  Samuel Clark

IPC: H01L31/0224 ,  H01L31/0735 ,  H01L31/073 ,  H01L21/329

CPC classification number: H01L31/022466 ,  H01L31/022433 ,  H01L31/035281 ,  H01L31/0693 ,  H01L31/073 ,  H01L31/0735 ,  Y02E10/544

Abstract: An optoelectronic device configured to operate at an electromagnetic radiation frequency having metal wire electrodes that are optically transparent as a result of the wires having an effective plasma frequency that is equal to or lower than the electromagnetic frequency at which the device operates. The effective plasma frequency of the wire is lowered by configuring the path of the wire between the terminal ends to be meandering, serpentine, U-shaped and in other non-linear configurations.

Abstract translation: 一种光电子器件，被配置为以具有等于或低于器件工作的电磁频率的有效等离子体频率的结果，以具有金属线电极的光学透明的电磁辐射频率工作。 线的有效等离子体频率通过将终端之间的线的路径配置为曲折，蛇形，U形和其它非线性配置来降低。

公开(公告)号：US09243290B2

公开(公告)日：2016-01-26

申请号：US13500578

申请日：2010-10-08

Applicant: Jeremy Edwards

Inventor： Jeremy Edwards

IPC: C12Q1/68

CPC classification number: C12Q1/6874 ,  C12Q1/6869 ,  C12Q2525/155 ,  C12Q2521/313 ,  C12Q2565/518 ,  C12Q2563/131 ,  C12Q2525/191

Abstract: We describe ultra-high throughput polony genome sequencing that can permit, for example, generating raw data to re-sequencing the human genome in about one week (including library prep and sequencing) at a reasonable cost. The methods described herein include one or more of the following: (1) increasing polony sequencing read length, (2) improving library construction and emulsions protocols, (3) increasing bead density and/or moving to alternative clonal amplication strategies (other than emulsion PCR or ePCR), (4) extending software capabilities to allow SNP calls from our new sequencing raw data, (5) Dual Primer Emulsion PCR, and (6) diagnostic method exploiting one or more of the foregoing.

Abstract translation: 我们描述了超高吞吐量的基因组测序，可以以合理的成本，在大约一周内（包括文库准备和测序），生成原始数据来重新测序人类基因组。 本文描述的方法包括以下一个或多个：（1）增加血清测序阅读长度，（2）改进文库构建和乳剂方案，（3）增加珠密度和/或移动到替代克隆扩增策略（乳液除外） PCR或ePCR），（4）扩展软件功能以允许来自我们的新测序原始数据的SNP呼叫，（5）双引物乳剂PCR，和（6）利用上述一种或多种的诊断方法。

公开(公告)号：US09152040B1

公开(公告)日：2015-10-06

申请号：US13365964

申请日：2012-02-03

Applicant: Steven R. J. Brueck ,  Alexander K. Raub

Inventor： Steven R. J. Brueck ,  Alexander K. Raub

IPC: G03F7/20 ,  G03F7/00 ,  C03B37/01

CPC classification number: G03F7/0005 ,  B82Y20/00 ,  G02F2202/32 ,  G03F7/2022 ,  G03F7/2041 ,  G03F7/32 ,  G03F7/40 ,  G03F7/70408

Abstract: In accordance with some aspects of the present disclosure, a maskless interferomeric lithography system for fabricating a three-dimensional (3D) photonic crystal using a multiple two-beam-exposures is disclosed. The system can comprise an illumination system comprising an optical arrangement operable to receive radiation from a radiation source and provide three or more tilted two-beam interference pattern exposures to be combined into a three-dimensional pattern; and a substrate operable to be supported by a substrate table, wherein the substrate comprises a photoresist formed on a top surface of the substrate and operable to receive the three-dimensional pattern and wherein means are provided to adjust the position of the substrate in all six mechanical degrees of freedom.

Abstract translation: 根据本公开的一些方面，公开了一种使用多个双光束曝光来制造三维（3D）光子晶体的无掩模干涉式光刻系统。 该系统可以包括照明系统，其包括光学装置，其可操作以接收来自辐射源的辐射并且提供三个或更多个倾斜的双光束干涉图案曝光以组合成三维图案; 以及可操作地由衬底台支撑的衬底，其中所述衬底包括形成在所述衬底的顶表面上并可操作以接收所述三维图案的光致抗蚀剂，并且其中提供用于调整所有六个衬底中的所述衬底的位置的装置 机械自由度。

公开(公告)号：US20150263353A1

公开(公告)日：2015-09-17

申请号：US14435762

申请日：2013-10-15

Applicant: Alexey SEROV ,  Plamen b. ATANASSOV ,  Barr HALEVI ,  Paul SHORT

Inventor： Alexey Serov ,  Plamen B. Atanassov ,  Barr Halevi ,  Paul Short

IPC: H01M4/90

CPC classification number: H01M4/9091 ,  B01J31/1805 ,  H01M4/8652 ,  H01M4/8814 ,  H01M4/8846 ,  H01M4/8885 ,  H01M4/9008 ,  H01M8/1011 ,  H01M2008/1095 ,  Y02E60/50 ,  Y02E60/523

Abstract: Novel catalytic materials and novel methods of preparing M—N—C catalytic materials utilizing a sacrificial support approach and using inexpensive active polymers as the carbon and nitrogen source and readily available metal precursors are described.

Abstract translation: 描述了新型催化材料和利用牺牲支撑方法制备M-N-C催化材料并使用廉价的活性聚合物作为碳源和氮源以及容易得到的金属前体的新方法。

公开(公告)号：US20150260521A1

公开(公告)日：2015-09-17

申请号：US13987911

申请日：2013-09-16

Applicant: Marek A. Osinski ,  Petr G. Eliseev ,  Edward W. Taylor

Inventor： Marek A. Osinski ,  Petr G. Eliseev ,  Edward W. Taylor

IPC: G01C19/72 ,  H01S3/102

CPC classification number: G01C19/727 ,  G01C19/66 ,  G02F1/3519 ,  H01S3/1028 ,  H01S5/1071 ,  H01S5/4068

Abstract: Method and apparatus embody a rotation sensor including one or more ring lasers designed to utilize a nonlinear Sagnac effect, a passive waveguide arrangement, and a photodetector arrangement to receive the outcoupled light and to detect rotation of the sensor; wherein these components are arranged into a monolithically integrated optoelectronic integrated circuit on a single substrate. The method and apparatus can include seeding a stable, rotation-insensitive, strong (driving) wave using a single-frequency edge emitting laser monolithically integrated on the same substrate.

Abstract translation: 方法和装置包括旋转传感器，其包括设计成利用非线性Sagnac效应的一个或多个环形激光器，无源波导装置和用于接收输出耦合的光并检测传感器的旋转的光电检测器装置; 其中这些部件被布置在单个基板上的单片集成光电集成电路中。 该方法和装置可以包括使用单一集成在同一衬底上的单频边缘发射激光器来播种稳定的，旋转不敏感的强（驱动）波。

公开(公告)号：US20150252339A1

公开(公告)日：2015-09-10

申请号：US14721024

申请日：2015-05-26

Applicant: Surojit Paul

Inventor： Surojit Paul

IPC: C12N9/16 ,  A61K38/46

CPC classification number: C12N9/16 ,  A61K38/00 ,  A61K38/465 ,  C12Y301/03048

Abstract: A novel peptide sequence that is a modified derivative of a neuron-specific tyrosine phosphatase is shown and described. Specifically, the novel peptide sequence is a modified derivative of striatal-enriched tyrosine phosphatase (STEP). The peptide sequence has been modified so as to be able to ameliorate and treat brain injury resulting from excessive glutamate release and/or oxidative stress. Examples of the types of brain injury which the presently disclosed peptide sequence is useful for treating includes acute brain injury resulting from stroke or traumatic brain injury and chronic disorders such as Huntington's chorea and schizophrenia. Furthermore, the presently described peptide sequence may further be useful in the treatment and amelioration of disorders associated with fear memory such as post-traumatic stress disorder.

Abstract translation: 显示和描述了作为神经元特异性酪氨酸磷酸酶的修饰衍生物的新型肽序列。 具体来说，新肽序列是纹状体富含酪氨酸磷酸酶的修饰衍生物（STEP）。 肽序列已被修饰，以便能够改善和治疗由过量的谷氨酸释放和/或氧化应激引起的脑损伤。 目前公开的肽序列可用于治疗的脑损伤类型的实例包括由中风或创伤性脑损伤引起的急性脑损伤和慢性疾病如亨廷顿氏舞蹈症和精神分裂症。 此外，目前描述的肽序列还可用于治疗和改善与恐惧记忆相关的疾病，例如创伤后应激障碍。

公开(公告)号：US09116246B2

公开(公告)日：2015-08-25

申请号：US13506240

申请日：2012-04-05

Applicant: Marek A. Osinski ,  Brian A. Akins ,  John B. Plumley ,  Antonio C. Rivera ,  Gennady A. Smolyakov ,  Jose M. Vargas ,  Nathan J. Withers

Inventor： Marek A. Osinski ,  Brian A. Akins ,  John B. Plumley ,  Antonio C. Rivera ,  Gennady A. Smolyakov ,  Jose M. Vargas ,  Nathan J. Withers

IPC: G01T3/06

CPC classification number: G01T3/06

Abstract: A thermal neutron detector and method employ Gd-containing nanoscintillators. Thermal neutron radiation is detected by observing scintillation events from the nanoscintillators.

Abstract translation: 一种热中子检测器和方法采用含Gd的纳米注射器。 通过观察来自纳米注射器的闪烁事件来检测热中子辐射。

公开(公告)号：US09116219B1

公开(公告)日：2015-08-25

申请号：US13655295

申请日：2012-10-18

Applicant: STC.UNM

Inventor： Stefan Posse

IPC: G01V3/00 ,  G01R33/56

CPC classification number: G01R33/5608 ,  G01R33/4806 ,  G01R33/4822 ,  G01R33/5616

Abstract: A system and methods for high-speed functional magnetic resonance imaging using multi-slab echo-volumar imaging (EVI), specifically a combination of multi-slab excitation and single-shot 3D encoding with parallel imaging to reduce geometrical image distortion and blurring, and to increase blood oxygenation level-dependent (BOLD) sensitivity compared to conventional echo-planar imaging (EPI).

Abstract translation: 一种使用多板回波 - 体积成像（EVI）的高速功能磁共振成像的系统和方法，特别是多平板激发和单次3D编码与并行成像的组合，以减少几何图像失真和模糊，以及 与常规回波平面成像（EPI）相比，增加血氧水平依赖性（BOLD）灵敏度。