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公开(公告)号：US20230316120A1
公开(公告)日：2023-10-05
申请号：US17999934
申请日：2021-06-03
Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
Inventor： Roee OZERI , Tom MANOVITZ , Yotam SHAPIRA , Nitzan AKERMAN , Adiel STERN
Abstract: Method and apparatus for quantum simulation, based on a linear chain of ions. A gradient field is imposed to break the symmetry of the ion chain, and bichromatic driving fields are applied to bridge the energy gaps induced by the gradient field and thereby establish resonance couplings among the ions according to their relative positions in the gradient field. The combination of the gradient field and the bichromatic driving fields implement excitation hopping to simulate a variety of topologies according to higher¬dimensional Hamiltonians and boundary conditions, including ring, torus, Mobius strip configurations, as well as topologies with periodic boundary conditions. In particular synthetic gauge fields allow simulation of magnetic flux.
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公开(公告)号：US20230313173A1
公开(公告)日：2023-10-05
申请号：US17787977
申请日：2020-12-22
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef SHAUL , Nina REUVEN
IPC: C12N15/10 , C12N9/22 , C12N15/11 , C12N5/071 , C12N15/113
CPC classification number: C12N15/102 , C12N9/22 , C12N15/11 , C12N5/0686 , C12N15/113 , C12N2310/20 , C12N2510/00 , C12N2310/14
Abstract: Kits and methods for selecting a cell harboring a genome-editing event at a target sequence of interest are disclosed. One such kit comprises:
(i) a first DNA editing agent for specifically introducing a mutation into a first gene so as to generate a first selection marker which imparts resistance to a selection agent, wherein the target sequence of interest the said first gene are distinct; and
(ii) the selection agent; and/or
(iii) a second DNA editing agent for specifically introducing a mutation into the first gene, wherein the mutation disrupts selection marker activity of the first selection marker.-
公开(公告)号：US20230301915A1
公开(公告)日：2023-09-28
申请号：US18202981
申请日：2023-05-29
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Jacob KLEIN , Ronit GOLDBERG , Weifeng LIN
CPC classification number: A61K9/1273 , A61P19/02 , A61K9/0019
Abstract: A liposome for use in delivering a therapeutically active agent to a subject in need thereof is disclosed herein. The liposome comprises:
a) at least one bilayer-forming lipid;
b) a polymeric compound having the general formula I:
wherein m, n, L, X, Y, and Z are as defined herein; and
c) a therapeutically active agent, incorporated in the liposome and/or on a surface of the liposome.-
公开(公告)号：US11764003B2
公开(公告)日：2023-09-19
申请号：US16896266
申请日：2020-06-09
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor： Milko E. Van Der Boom , Michal Lahav , Neta Elool Dov , Ofir Eisenberg , Yadid Algavi
CPC classification number: H01G11/24 , H01G11/04 , H01G11/36 , H01G11/46 , H01G11/48 , H01G11/54 , C08G61/126 , H02J2207/50
Abstract: A hybrid supercapacitor where the charging state is indicated by color is demonstrated. The device comprises a molecular network that functions as both the battery-type electrode and the charge indicator. Related batteries, electrodes and devices, their processes of preparation and methods of use are provided as well.
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45.发明授权公开(公告)号：US11746006B2
公开(公告)日：2023-09-05
申请号：US17416772
申请日：2019-12-30
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor： David Milstein , You-Quan Zou , Aviel Anaby
CPC classification number: C01B3/0015 , B01J31/189 , B01J31/20 , B01J31/2404 , B01J2231/763 , B01J2531/821
Abstract: This invention provides a reversible hydrogen loading and discharging system and a reversible method for loading and discharging hydrogen. The system and the methods of this invention comprise ethylene glycol as a liquid organic hydrogen carrier and at least one transition metal. By reacting ethylene glycol with at least one transition metal; at least one hydrogen molecule and at least one oligoester of ethylene glycol are formed (hydrogen releasing)⋅, and by reacting at least one oligoester of ethylene glycol with at least one transition metal and at least one hydrogen molecule, at least one ethylene glycol is formed (hydrogen loading).
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Patent Agency Ranking
公开(公告)号：US20230263884A1
公开(公告)日：2023-08-24
申请号：US18122169
申请日：2023-03-16
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Gideon SCHREIBER , Jiri ZAHRADNIK , Yinon RUDICH
IPC: A61K39/215 , C07K14/005
CPC classification number: A61K39/215 , C07K14/005 , A61K38/00
Abstract: A polypeptide comprising an amino acid sequence of SARS CoV-2 receptor-binding domain (RBD) is disclosed, wherein said amino acid sequence comprises a modification at position 358 and at least two additional modifications at two positions selected from the group consisting of 484, 498 and 501, wherein the polypeptide binds soluble, monomeric angiotensin-converting enzyme 2 (ACE2) receptor. Uses thereof are further disclosed.
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公开(公告)号：US20230248779A1
公开(公告)日：2023-08-10
申请号：US18137455
申请日：2023-04-21
Applicant: Kadimastem Ltd. , Yeda Research and Development Co. Ltd.
Inventor： Kfir MOLAKANDOV , Neta LAVON , Avital BECK , Michel REVEL , Ofer ELHANANI , Yoav SOEN , Michael WALKER , Arye HASSON
CPC classification number: A61K35/39 , C12N5/0676 , A61P5/50 , A61P3/10 , C12N2506/45 , C12N2500/38 , C12N2500/34 , C12N2506/02 , C12N2501/599 , C12N2500/25
Abstract: The present invention relates to compositions and methods comprising cell surface markers for pluripotent-derived cells, in particular, pancreatic endoderm-type cells, derived from pluripotent stem cells.
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公开(公告)号：US20230235464A1
公开(公告)日：2023-07-27
申请号：US18002661
申请日：2021-06-17
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor： Ronny NEUMANN , Yehonatan KAUFMAN
IPC: C25B3/07 , C25B3/23 , C25B15/027 , C25B11/065 , C25B11/061 , C25B11/077 , C25B11/081
CPC classification number: C25B3/07 , C25B3/23 , C25B15/027 , C25B11/065 , C25B11/061 , C25B11/077 , C25B11/081
Abstract: This invention is directed to a method of oxygenating hydrocarbons with molecular oxygen, O2, as oxidant under electrochemical reducing conditions, using polyoxometalate compounds containing copper such as Q10[Cu4(H2O)2(B-α-PW9O34)2] or Q13{[Cu(H2O)]3[(A-α-PW9O34)2(NO3)−]} or solvates thereof as catalysts, wherein Q are each independently selected from alkali metal cations, alkaline earth metal cations, transition metal cations, NH4+, H+ or any combination thereof.
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公开(公告)号：US11680263B2
公开(公告)日：2023-06-20
申请号：US17227483
申请日：2021-04-12
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Alon Chen , Orna Issler
IPC: C12N15/113 , C12Q1/6883 , C12N15/11 , C07H21/02
CPC classification number: C12N15/113 , C12N15/111 , C12Q1/6883 , C12N2310/141 , C12N2320/30 , C12Q2600/158 , C12Q2600/178
Abstract: A method of treating a bipolar disorder in a subject in need thereof is disclosed. The method comprising administering to the subject sa therapeutically effective amount of a miR-135, a precursor thereof or a nucleic acid molecule encoding said miR-135 or said precursor thereof, thereby treating the bipolar disorder. Methods of diagnosing a mood disorder in a human subject and of monitoring treatment of an anti-depressant drug or a medicament for the treatment of a mood disorder are also disclosed.
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公开(公告)号：US11645537B2
公开(公告)日：2023-05-09
申请号：US16746887
申请日：2020-01-19
Inventor： Zhichao Li , Yushu Gao , Yifeng Geng , Heng Luo
Abstract: Disclosed are a neural network training method, a neural network training device and an electronic device. The neural network training method includes: training a first neural network to be trained by using sample data; determining an indicator parameter of the first neural network in a current training process; determining an update manner corresponding to a preset condition if the indicator parameter meets the preset condition; and updating a parameter of a batch normalization layer in the first neural network based on the update manner. In this way, sparsing of a feature map output by a neural network is implemented, thereby reducing an amount of data to be transmitted and improving computation speed of a chip.
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