Abstract:
Methods and apparatus, including systems and computer program products, for a services architecture design that provides enterprise services having accounting functionality at the level of an enterprise application. The design includes a set of service operations, process components, and optionally deployment units. Suitable business objects are also described.
Abstract:
A multi-use variable guard rail system for providing a safe working area is mountable on various surfaces, whether sloped (roofs), vertical (walls) or horizontal (floors). A rail support of the system has an upright pivotally engaged with a base, and a brace that locks the upright relative to the base in numerous positions ranging between an acute angle and an obtuse angle where the upright and base are linearly aligned. The upright has openings that hold rails such as various sizes of lumber in a vertically stacked array without the need to cut or fasten the lumber, and which allows for replacement of rails without disassembly of the rest of the system. The base has a tongue particularly suited for roof work, namely it is used to mount the rail support to the roof, yet allows the base to be lifted for placing shingles thereunder.
Abstract:
This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, results in decrease in the in vivo bioavailability of first transition series elements and/or removal from the body of first transition series elements and elements with similar chemical properties. These characteristics make such compounds useful in the management of diseases associated with a bodily excess of first transition series elements and elements with similar chemical properties. This invention demonstrates that such compounds inhibit mammalian, bacterial, and fungal cell replication and are therefore useful in the treatment of neoplasia, infection, inflammation, immune reponse, and in termination of pregnancy. Since these compounds are capable of descreasing the in vivo availability of tissue iron they are useful in management of free radical mediated tissue damage, and oxidation mediated tissue damage. When combined with radioisotopic or paramagnetic cations of first transition series elements, or elements with chemical properties similar to those of first transition series elements, prior to their administration, the resulting complexes are useful as diagnostic agents in nuclear medicine and magnetic resonance imaging (MRI).
Abstract:
Polyamines containing at least two nitrogen atoms monosubstituted with pendant arms capable of coordinating metal cations, or with precursors of such pendant arms, all nitrogen atoms of the polyamines except two being fully substituted and the remaining two bearing one H atom each, are cyclized by reaction with a bridging agent that contains two sites that each bear a reactive group capable of undergoing a nucleophilic attack by one of the two N-H groups on the polyamine. Unlike the prior art, cyclization occurs in preference over polymerization of the polyamine, even in reaction mixtures in which the polyamine is at high concentration. A process is also disclosed whereby linear polyamines in which the terminal amine groups are primary amines are substituted with methylenephosphonate ester groups, with one such substituent on each nitrogen atom of the polyamine. The process involves the use of a trialkyl or triaryl phosphite, and unlike the prior art, monosubstitutions at all nitrogen atoms are achieved in preference over disubstitutions at the terminal primary amines. Finally, a novel class of N,N′,N″-tris(methylenephosphonate or methylephosphonic acid-substituted)-1,4,7-triazaheptanes are disclosed as new compositions of matter.
Abstract:
This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, results in decrease in the in vivo bioavailability of first transition series elements and/or removal from the body of first transition series elements and elements with similar chemical properties. These characteristics make such compounds useful in the management of diseases associated with a bodily excess of first transition series elements and elements with similar chemical properties. This invention demonstrates that such compounds inhibit mammalian, bacterial, and fungal cell replication and are therefore useful in the treatment of neoplasia, infection, inflammation, immune response, and in termination of pregnancy. Since these compounds are capable of descreasing the in vivo availability of tissue iron they are useful in management of free radical mediated tissue damage, and oxidation mediated tissue damage. When combined with radioisotopic or paramagnetic cations of first transition series elements, or elements with chemical properties similar to those of first transition series elements, prior to their administration, the resulting complexes are useful as diagnostic agents in nuclear medicine and magnetic resonance imaging (MRI).
Abstract:
A dispenser/separator for contamination-free dispensing of a supply of cut-separable medical devices is disclosed which includes anti-contamination structure for enclosing the supply. The anti-contamination structure includes an exit port for allowing the supply to be pulled therethrough in a first direction to expose a device. Also disclosed is a cutter for separating such an exposed device from the supply by pulling the supply against the cutter in a second direction that is at an oblique angle relative to the first direction. In the preferred embodiment, the exit port takes the form of a resistance control aperture, and the cutter takes the form of a stationary knife blade that is positioned adjacent the aperture.
Abstract:
The sculpture is created by accreting successive layers of a vitreous material under close temperature control on a core to form a solid unified mass and of depositing pellicular images on one or more of said layers; said images, which may be photographically generated, being variously sinuous, discrete, diaphanous, colored and spaced apart from each other in both radial and axial directions of the solid mass which constitutes the sculpture and which is characterized by said images apparently floating freely within the mass composing a general design, scene, display or decoration.
Abstract:
Method and apparatus in which a selected coating is applied to specific surfaces within a plasticating extruder to change the coefficient of friction between the solids being conveyed in the extruder and the specific surfaces in such a way as to improve solids conveying and thereby increase the production effectiveness of the extruder.