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公开(公告)号:US20190183665A1
公开(公告)日:2019-06-20
申请号:US16328094
申请日:2016-09-05
Inventor: Myung-Gyu Choi , Seok-Hyun Yun , Bo-In Lee , Jae Myung Park , Ehsan Kamrani , Ali Kemal Yetisen
CPC classification number: A61F2/82 , A61B5/076 , A61B5/1473 , A61B5/6862 , A61F7/00 , A61F7/12 , A61F2002/482 , A61F2007/0094 , A61F2007/126 , A61F2250/0001 , A61N1/37223 , A61N1/3787 , A61N5/0601 , A61N5/062 , A61N2005/0651
Abstract: The present invention relates to a stent using wirelessly transmitted power, and to an external driving device thereof. To this end, a stent is provided with: a power receiving part wirelessly receiving power from the outside; a power storing part storing the power; a second communicating part receiving a control command from the outside; an electrical stimulation part generating electrical stimulation by using the power; a photosensitizer coated onto a stent; an LED illuminating the vicinity of the stent; and a second control part controlling the heat-generating stent on the basis of the control command.
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公开(公告)号:US10251936B2
公开(公告)日:2019-04-09
申请号:US15974647
申请日:2018-05-08
Inventor: Tai Gyu Kim , Hyun Il Cho
IPC: A61K38/17 , C07K14/70 , C07K14/725
Abstract: The present invention relates to an EBV antigen specific T-cell receptor and the use thereof. Specifically, the present invention provides T cells specific for LMP1 of EBV using a T-cell receptor which is highly specific for specific epitopes derived from an EBV antigen, LMP1. In addition, the EBV antigen specific T-cell can be used in the prevention or treatment of EBV-associated diseases.
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公开(公告)号:US20190038150A1
公开(公告)日:2019-02-07
申请号:US16074636
申请日:2017-01-25
Inventor: Jin Hee JANG , Yoon Ho NAM , Bum Soo KIM
IPC: A61B5/026 , G06T7/00 , G01R33/563 , G01R33/56
CPC classification number: A61B5/0263 , A61B5/00 , A61B5/02 , A61B5/026 , A61B5/055 , A61B5/7278 , A61B6/504 , G01R33/4818 , G01R33/5601 , G01R33/5635 , G01R33/56366 , G06T7/0012 , G06T7/11 , G06T2207/20032 , G06T2207/30104
Abstract: Provided is a technique for deriving a mathematical function for defining arterial and venous blood flow in the body by using a four-dimensional medical image. A method of analyzing blood flow by using a medical image according to an embodiment of the present disclosure includes: determining a position of a blood vessel from four-dimensional medical image data that is obtained by combining data of three-dimensional medical images of a patient's body captured at a preset period; deriving a primary function for an arterial input function and a venous output function by using a vascular signal in a head region and a vascular signal in a heart region from among vascular signals included in three-dimensional medical image data for the position of the blood vessel determined in the determining; and deriving a secondary function that is a final function for the arterial input function and the venous output function by using the primary function and a vascular signal in a neck region.
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公开(公告)号:US10195166B2
公开(公告)日:2019-02-05
申请号:US15032717
申请日:2014-10-28
Inventor: Seung Kew Yoon , Jung Hee Kim , Won Hee Hur , Mi La Cho , Jung Eun Choi , Eun Byul Lee
IPC: A61K38/17 , A61K31/155 , A61K31/196 , C12N15/113 , A61K31/7072 , A61K31/7105 , A61K38/00 , A61K48/00
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating hepatitis C virus (HCV) infectious disease. More particularly, the present invention relates to a pharmaceutical composition for preventing or treating HCV infectious disease or an antiviral composition for HCV, containing at least one selected from the group consisting of: GRIM19 protein or a fragment thereof; and a gene encoding the protein or a fragment of the protein.
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45.
公开(公告)号:US10155024B2
公开(公告)日:2018-12-18
申请号:US14671626
申请日:2015-03-27
Inventor: Seok Goo Cho , Nayoun Kim
Abstract: Provided is a pharmaceutical composition for preventing or treating B-cell lymphoma including IL-21 expressing mesenchymal stem cells, and a treating method using the same.
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公开(公告)号:US20180256921A1
公开(公告)日:2018-09-13
申请号:US15565591
申请日:2016-03-31
Inventor: MIN-SEOK CHO , TAE-HO KIM , SEONG-HEE KANG , DONG-SU KIM , KYEONG-HYEON KIM , DONG-SEOK SHIN , SI YONG KIM , TAE SUK SUH
IPC: A61N5/10
CPC classification number: A61N5/1049 , A61N5/1064 , A61N5/1067 , A61N2005/1097 , G01L1/04 , G01L7/182
Abstract: The present invention relates to a thermoplastic mask monitoring system using a pressure sensor. Specifically, a thermoplastic mask according to the present invention may include: a mask having a shape determined according to a shape of a first region which is at least a part of a patient's body by using thermoplasticity, fixing the first region in close contact with the first region, and receiving radiation; and a pressure sensor provided between the mask and the first region and sensing pressure induced by a space generated between the mask and the first region.
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公开(公告)号:US10070872B2
公开(公告)日:2018-09-11
申请号:US14759230
申请日:2015-04-30
Inventor: Jae Jun Kim
CPC classification number: A61B17/1631 , A61B17/00234 , A61B17/1613 , A61B17/1622 , A61B2017/00398 , A61B2017/00415
Abstract: Disclosed is a medical motor drill having an angle adjusting function. The medical motor drill includes a main body, a shaft connected to the main body, a drill unit connected to the shaft so as to be bendable relative to the shaft, the drill unit including a motor configured to receive power from the main body and a drill blade configured to be rotated by the motor, a drive force transmission unit configured to bend the drill unit relative to the shaft, and an angle adjustment unit connected to the drive force transmission unit to adjust a bending degree of the drill unit. The medical motor drill has advantages of enabling drilling over a wide range in a state in which a drill manipulation position is fixed and of enabling adjustment in the angle of the drill unit that is located distant from a user manipulation position.
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公开(公告)号:US20180118668A1
公开(公告)日:2018-05-03
申请号:US15819758
申请日:2017-11-21
Inventor: Mi-La CHO , Dong-Yun SHIN , Sung-Hwan PARK , Chul-Woo YANG , Jong-Young CHOI , Min-Jung PARK , Hye-Jin SON , Sung-Hee LEE , Seon-Yeong LEE , Eun-Kyung KIM , Jae-Kyung KIM , Seung-Hun LEE , Seong-Hyeok PARK
IPC: C07C279/18
CPC classification number: C07C279/18 , C07C279/26
Abstract: The present invention relates to a novel compound capable of effectively preventing and treating immune diseases and a use thereof. The novel compound of the present invention has effects of inhibiting the production of inflammatory cytokines, increasing the activity of regulatory T cells having immunoregulatory functions, inhibiting the production of auto-antibodies to regulate excessive immune responses, and inhibiting the differentiation of osteoclasts, and thus can be used for treating immune diseases, such as autoimmune disease, inflammatory disease, and transplant rejection diseases, which are caused by abnormal regulation of various kinds of immune response
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49.
公开(公告)号:US20180080029A1
公开(公告)日:2018-03-22
申请号:US15562894
申请日:2016-04-06
Inventor: Joo Young LEE , Gabsik YANG
IPC: C12N15/113 , A61K8/60 , A61Q19/00 , A23L33/13
CPC classification number: C12N15/1136 , A23L33/13 , A23V2002/00 , A61K8/606 , A61Q19/00 , C12N15/113 , C12N15/117 , C12N2310/17 , C12N2310/50 , C12N2310/52
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating atopic dermatitis, the pharmaceutical composition including, as an active ingredient, X-shaped DNA (XL-DNA) formed by complementary binding of oligonucleotides having nucleotide sequences of SEQ ID NO: 1 to SEQ ID NO: 4. When the pharmaceutical composition is subcutaneously injected into an animal model of atopic dermatitis, effects of easing skin lesions, such as erythema, bleeding and edema, and the like, and ear edema, and reducing expression of immunoglobulin E (IgE) are exhibited. In this regard, the composition can be used as a pharmaceutical composition, a health food, or a cosmetic for atopic dermatitis.
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公开(公告)号:US09868697B2
公开(公告)日:2018-01-16
申请号:US14299746
申请日:2014-06-09
Inventor: Byung-Hak Kim , Tae-Yoon Kim , Sanghee Kim
IPC: C07C235/74 , C07C231/02 , A61Q19/00 , C07C235/76 , A61K8/68 , A61K31/197
CPC classification number: C07C235/74 , A61K8/68 , A61K31/197 , A61Q19/00 , C07C231/02 , C07C235/76
Abstract: A phytosphingosine derivative of chemical formula IA or IB, and a composition comprising the phytosphingosine derivative for preventing and treating inflammatory skin diseases, autoimmune diseases, and hyperkeratotic diseases. The phytosphingosine derivatives of the present disclosure are involved with transcription factors related to inflammation, autoimmune diseases and hyperkeratotic diseases, the expression and the generation of inflammatory mediators, signal transduction mechanisms, and the expression and the activity of relevant enzymes and the like.
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