DECOMPOSITION OF NEAR-FIELD REFLECTIONS
    41.
    发明申请
    DECOMPOSITION OF NEAR-FIELD REFLECTIONS 审中-公开
    近场反射的分解

    公开(公告)号:US20150134288A1

    公开(公告)日:2015-05-14

    申请号:US14286858

    申请日:2014-05-23

    CPC classification number: G01S7/292 G01S13/885 G01S13/887

    Abstract: Systems and methods for decomposition of near-field reflections are presented. In an embodiment, a method may include identifying data associated with a reference signal in a reflection-based imaging device. The method may also include identifying shifted and scaled versions of the reference signal in reflection data gathered by the reflection-based imaging device. Additionally, the method may include solving a time-of-arrival and a scaling factor of the reference signal with a non-linear optimization.

    Abstract translation: 提出了近场反射分解的系统和方法。 在一个实施例中,方法可以包括在基于反射的成像装置中识别与参考信号相关联的数据。 该方法还可以包括识别由基于反射的成像装置收集的反射数据中的参考信号的偏移和缩放版本。 另外,该方法可以包括通过非线性优化来求解参考信号的到达时间和缩放因子。

    Metabolite Biomarkers for Diagnosis and Prognosis of Pediatric Septic Shock
    42.
    发明申请
    Metabolite Biomarkers for Diagnosis and Prognosis of Pediatric Septic Shock 有权
    代谢物生物标志物诊断和预后的小儿脓毒性休克

    公开(公告)号:US20140205591A1

    公开(公告)日:2014-07-24

    申请号:US14160712

    申请日:2014-01-22

    CPC classification number: G01R33/465 G01N24/08

    Abstract: The present invention provides methods for differentiating a pediatric subject with pediatric septic shock from a healthy pediatric subject or one having sudden inflammatory response syndrome (SIRS). Also provided is a method of predicting pediatric septic shock mortality in a pediatric septic shock patient.

    Abstract translation: 本发明提供了将儿科受试者与来自健康儿科受试者或具有突发性炎症反应综合征(SIRS)的儿科败血性休克区分开的方法。 还提供了一种预测儿科脓毒性休克患者儿科败血性休克死亡率的方法。

    Methods and Apparatuses for Full-Thickness Hollow Organ Biopsy
    43.
    发明申请
    Methods and Apparatuses for Full-Thickness Hollow Organ Biopsy 审中-公开
    全厚度空心器官活检的方法和装置

    公开(公告)号:US20140188000A1

    公开(公告)日:2014-07-03

    申请号:US14144316

    申请日:2013-12-30

    CPC classification number: A61B10/0275 A61B2010/0208

    Abstract: A method for obtaining a full thickness biopsy of the wall of a hollow organ, comprising obtaining an apparatus comprising a cannula comprising a proximal cannula end comprising a cutting edge; and a distal cannula end comprising a biased spring, the biased spring being coupled to a needle carrier and a releasable lock; and a needle disposed within the cannula and carried on the needle carrier, the needle comprising: a tip; a flange; a notch portion comprising a notch thickness; and a shaft comprising a shaft thickness; where the shaft thickness is greater than the notch thickness and the releasable lock is configured to hold the cannula in a withdrawn position relative to the needle; obtaining a patient having skin, a first wall, and a second wall; creating an incision through the skin of the patient; inserting the apparatus into the incision; advancing the apparatus through the first wall and the second wall; withdrawing the cannula relative to the needle; locking the cannula with the releasable lock; aligning the notch portion such that the notch portion straddles the second wall; releasing the releasable lock such that the cutting edge of the cannula passes completely through the second wall creating a full-thickness biopsy; and withdrawing the apparatus from the patient.

    Abstract translation: 一种用于获得中空器官壁的全层活检的方法,包括获得包括套管的装置,所述插管包括包括切割边缘的近侧插管端; 以及包括偏置弹簧的远端插管端,所述偏置弹簧联接到针托架和可释放锁; 以及设置在所述套管内并承载在所述针架上的针,所述针包括:尖端; 法兰 切口部分,包括凹口厚度; 以及包括轴厚度的轴; 其中所述轴厚度大于所述切口厚度,并且所述可释放锁定构造成将所述套管保持在相对于所述针的缩回位置; 获得具有皮肤的患者,第一壁和第二壁; 通过患者的皮肤创建切口; 将装置插入切口; 通过第一壁和第二壁推进装置; 相对于针抽出插管; 用可释放的锁锁定套管; 对准所述切口部分使得所述切口部分跨越所述第二壁; 释放可释放的锁,使得插管的切割边缘完全穿过第二壁,产生全层活检; 并从患者身上取出装置。

    WIDE DYNAMIC RANGE DISPLAY
    44.
    发明申请
    WIDE DYNAMIC RANGE DISPLAY 审中-公开
    宽动态范围显示

    公开(公告)号:US20140092116A1

    公开(公告)日:2014-04-03

    申请号:US13921177

    申请日:2013-06-18

    CPC classification number: G06T11/001 G06T3/4015

    Abstract: Methods and systems for wide dynamic range display are presented. In one embodiment, a method includes receiving a Color Filter Array (CFA) pixel signal, computing, using image processing hardware, an adaptation factor for the CFA pixel signal, the adaptation factor having a global factor component and a local factor component, and computing, using the image processing hardware, an adapted pixel signal for the CFA pixel in response to a reverse exponential function featuring the adaptation factor. In one embodiment, computing the adapted pixel signal for the CFA pixel does not require frame memory. Also, the adaptation factor may have a value between 0 and 1, in certain embodiments.

    Abstract translation: 介绍了宽动态范围显示的方法和系统。 在一个实施例中,一种方法包括接收彩色滤波器阵列(CFA)像素信号,使用图像处理硬件来计算CFA像素信号的自适应因子,适应因子具有全局因子分量和局部因子分量,以及计算 ,使用所述图像处理硬件,响应于具有所述自适应因子的反向指数函数,所述适用于所述CFA像素的像素信号。 在一个实施例中,计算用于CFA像素的适配像素信号不需要帧存储器。 此外,在某些实施例中,适配因子可以具有介于0和1之间的值。

    Method and system for sustained-release of sclerosing agent
    46.
    发明授权
    Method and system for sustained-release of sclerosing agent 有权
    硬化剂持续释放的方法和系统

    公开(公告)号:US08529542B2

    公开(公告)日:2013-09-10

    申请号:US13675931

    申请日:2012-11-13

    Inventor: Alain Tremblay

    Abstract: Methods and systems for treating pleural disease comprising a providing a low dosage of a sclerosing agent over a period of time. Certain examples include catheter with a sclerosing agent that is inserted into the pleural space. The sclerosing agent is released in a sustained-release manner over a period of time to achieve diffuse pleurodesis of the pleural layers.

    Abstract translation: 用于治疗胸膜疾病的方法和系统,其包括在一段时间内提供低剂量的硬化剂。 某些实例包括插入胸膜腔的具有硬化剂的导管。 在一段时间内以持续释放的方式释放硬化剂以实现胸膜层的弥漫性胸膜固定术。

    Halogenated Xanthenes as Vaccine Adjuvants
    49.
    发明公开

    公开(公告)号:US20240316191A1

    公开(公告)日:2024-09-26

    申请号:US18581095

    申请日:2024-02-19

    CPC classification number: A61K39/39 A61K39/0011 A61K2039/55511

    Abstract: A method of inducing a Type I interferon response in a mammalian subject that presents with a microbial infection, cancerous tumor or hematological malignancy that comprises administering an amount of a halogenated xanthene as discussed above, effective to induce the Type I interferon response. A method of enhancing a mammalian immunogen-specific immune response that comprises contacting mammalian cells, in vivo or present in a mammalian cell growth supporting medium, with an adjuvant-effective amount of a halogenated xanthene, and an immunogen to which that response is to be enhanced. A mammalian HX compound-adjuvanted vaccine composition that contains an immunogen present in a vaccine-effective amount along with an adjuvant-effective amount of a halogenated xanthene (HX) compound and one or more excipients present at about 0.001% by weight to 10% by weight of the vaccine composition dissolved or dispersed in a pharmaceutically acceptable diluent.

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