Abstract:
Systems and methods for decomposition of near-field reflections are presented. In an embodiment, a method may include identifying data associated with a reference signal in a reflection-based imaging device. The method may also include identifying shifted and scaled versions of the reference signal in reflection data gathered by the reflection-based imaging device. Additionally, the method may include solving a time-of-arrival and a scaling factor of the reference signal with a non-linear optimization.
Abstract:
The present invention provides methods for differentiating a pediatric subject with pediatric septic shock from a healthy pediatric subject or one having sudden inflammatory response syndrome (SIRS). Also provided is a method of predicting pediatric septic shock mortality in a pediatric septic shock patient.
Abstract:
A method for obtaining a full thickness biopsy of the wall of a hollow organ, comprising obtaining an apparatus comprising a cannula comprising a proximal cannula end comprising a cutting edge; and a distal cannula end comprising a biased spring, the biased spring being coupled to a needle carrier and a releasable lock; and a needle disposed within the cannula and carried on the needle carrier, the needle comprising: a tip; a flange; a notch portion comprising a notch thickness; and a shaft comprising a shaft thickness; where the shaft thickness is greater than the notch thickness and the releasable lock is configured to hold the cannula in a withdrawn position relative to the needle; obtaining a patient having skin, a first wall, and a second wall; creating an incision through the skin of the patient; inserting the apparatus into the incision; advancing the apparatus through the first wall and the second wall; withdrawing the cannula relative to the needle; locking the cannula with the releasable lock; aligning the notch portion such that the notch portion straddles the second wall; releasing the releasable lock such that the cutting edge of the cannula passes completely through the second wall creating a full-thickness biopsy; and withdrawing the apparatus from the patient.
Abstract:
Methods and systems for wide dynamic range display are presented. In one embodiment, a method includes receiving a Color Filter Array (CFA) pixel signal, computing, using image processing hardware, an adaptation factor for the CFA pixel signal, the adaptation factor having a global factor component and a local factor component, and computing, using the image processing hardware, an adapted pixel signal for the CFA pixel in response to a reverse exponential function featuring the adaptation factor. In one embodiment, computing the adapted pixel signal for the CFA pixel does not require frame memory. Also, the adaptation factor may have a value between 0 and 1, in certain embodiments.
Abstract:
The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
Abstract:
Methods and systems for treating pleural disease comprising a providing a low dosage of a sclerosing agent over a period of time. Certain examples include catheter with a sclerosing agent that is inserted into the pleural space. The sclerosing agent is released in a sustained-release manner over a period of time to achieve diffuse pleurodesis of the pleural layers.
Abstract:
Silica modified vaterite Janus nanoparticles are provided, together with methods for the synthesis of such particles. The disclosed methods make use of a Pickering emulsion, in a scalable aqueous process. The silica-modified surface is amenable to chemical modification, for example with physiologically acceptable labels.
Abstract:
The present application relates to metal-organic frameworks (MOFs). More specifically, the present application relates to process for their preparation and uses thereof. The present application includes a process for preparing a chromium (III) phosphonate metal-organic framework (MOF) comprising: a) dehydrating a hydrogen-bonded metal-organic framework (HMOF) comprising chromium (III) hydrogen bonded to one or more organic polyphosphonate molecule by heating the HMOF at a controlled rate; b) cooling the dehydrated HMOF from a) to provide the MOF.
Abstract:
A method of inducing a Type I interferon response in a mammalian subject that presents with a microbial infection, cancerous tumor or hematological malignancy that comprises administering an amount of a halogenated xanthene as discussed above, effective to induce the Type I interferon response. A method of enhancing a mammalian immunogen-specific immune response that comprises contacting mammalian cells, in vivo or present in a mammalian cell growth supporting medium, with an adjuvant-effective amount of a halogenated xanthene, and an immunogen to which that response is to be enhanced. A mammalian HX compound-adjuvanted vaccine composition that contains an immunogen present in a vaccine-effective amount along with an adjuvant-effective amount of a halogenated xanthene (HX) compound and one or more excipients present at about 0.001% by weight to 10% by weight of the vaccine composition dissolved or dispersed in a pharmaceutically acceptable diluent.
Abstract:
An example a method of manufacturing a film is provided. The method involves dissolving a backbone material in a non-aqueous solvent to form a non-aqueous solution. The method further involves adding the non-aqueous solution to an aqueous solution to form a liquid-liquid interface and injecting a particulate proximate to the liquid-liquid interface the non-aqueous solution is then evaporated to form a film containing the particulate. The film may be used in devices such as sensor devices for detecting hydrocarbons.