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公开(公告)号：US20120226121A1
公开(公告)日：2012-09-06
申请号：US13473352
申请日：2012-05-16
IPC分类号： A61B5/1473
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译： 本文公开了用于校准连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用一个或多个电极来测量另外的分析物。 这样的测量可以提供用于校准传感器的基线或灵敏度测量。 此外，可以使用基线和/或灵敏度测量来触发诸如数字数字滤波或暂停显示数据的事件。
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公开(公告)号：US08792955B2
公开(公告)日：2014-07-29
申请号：US13157031
申请日：2011-06-09
申请人： Mark Brister , Paul V. Neale , Peter C. Simpson , James H. Brauker , James Patrick Thrower , Mark Shults , Rathburn K. Rhodes , Paul V. Goode, Jr. , Arnold L. Holmquist
发明人： Mark Brister , Paul V. Neale , Peter C. Simpson , James H. Brauker , James Patrick Thrower , Mark Shults , Rathburn K. Rhodes , Paul V. Goode, Jr. , Arnold L. Holmquist
IPC分类号： A61B5/1473 , A61B5/145
CPC分类号： A61B5/0015 , A61B5/0031 , A61B5/076 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B2560/04 , A61B2560/0462 , A61B2562/247 , H04B1/03
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号：US08449464B2
公开(公告)日：2013-05-28
申请号：US12267546
申请日：2008-11-07
申请人： Peter C. Simpson , Michael J. Estes , Paul V. Neale , Robert Boock , Jacob S. Leach , Richard C. Yang , Mark Brister
发明人： Peter C. Simpson , Michael J. Estes , Paul V. Neale , Robert Boock , Jacob S. Leach , Richard C. Yang , Mark Brister
CPC分类号： C12Q1/001 , A61B5/0031 , A61B5/145 , A61B5/14532 , A61B5/14539 , A61B5/14542 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/412 , A61B5/4839 , A61B5/6848 , A61B5/6849 , A61B5/7275 , A61B5/743 , A61B2560/0223 , A61B2560/04 , A61B2562/085 , A61M5/14 , A61M5/16804 , A61M5/1723 , A61M25/007 , A61M2005/14296 , A61M2230/201 , C12Q1/006 , G06F19/3468 , G16H40/40 , Y02A90/26
摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
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44.发明授权Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise 有权具有基本上不受非恒定噪声影响的信噪比的分析物传感器公开(公告)号：US08364229B2
公开(公告)日：2013-01-29
申请号：US11750907
申请日：2007-05-18
申请人： Peter C. Simpson , Robert Boock , James R. Petisce , Mark Brister , Monica A. Rixman , Kum Ming Woo , Lisa Nguyen , Seth R. Brunner , Arthur Chee , Melissa A. Nicholas , Matthew Wightlin , Jack Pryor , Dubravka Markovic
发明人： Peter C. Simpson , Robert Boock , James R. Petisce , Mark Brister , Monica A. Rixman , Kum Ming Woo , Lisa Nguyen , Seth R. Brunner , Arthur Chee , Melissa A. Nicholas , Matthew Wightlin , Jack Pryor , Dubravka Markovic
CPC分类号： A61B5/00 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B5/6848 , A61B5/7203
摘要： Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
摘要翻译： 提供涉及具有基本上不受非恒定噪声影响的信噪比的传感器的系统和方法用于主机中的连续分析物测量。 在一些实施例中，连续分析物测量系统被配置为完全，经皮，血管内或体外植入。
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公开(公告)号：US07828728B2
公开(公告)日：2010-11-09
申请号：US11675063
申请日：2007-02-14
申请人： Robert Boock , Monica Rixman , James H. Brauker , James R. Petisce , Peter C. Simpson , Mark Brister , Mark A. Tapsak , Victoria Carr-Brendel
发明人： Robert Boock , Monica Rixman , James H. Brauker , James R. Petisce , Peter C. Simpson , Mark Brister , Mark A. Tapsak , Victoria Carr-Brendel
CPC分类号： A61B5/14865 , A61B5/0031 , A61B5/14532 , A61B5/418 , B33Y70/00
摘要： The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable devices including these membranes.
摘要翻译： 本发明一般涉及与可植入装置一起使用的膜，例如用于检测生物样品中分析物浓度的装置。 更具体地说，本发明涉及新的有机硅 - 亲水性聚合物共混膜，以及包括这些膜的装置和可植入装置。
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公开(公告)号：US10022078B2
公开(公告)日：2018-07-17
申请号：US11439630
申请日：2006-05-23
IPC分类号： A61B5/1486 , A61B5/1473 , G01N33/66 , A61B5/145 , A61B5/00 , C12Q1/00 , G01N33/543
摘要： The present invention relates generally to biointerface membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel biointerface membranes, to devices and implantable devices including these membranes, methods for forming the biointerface membranes on or around the implantable devices, and to methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device.
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公开(公告)号：USRE43039E1
公开(公告)日：2011-12-20
申请号：US12839260
申请日：2010-07-19
IPC分类号： A61B5/05
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译： 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用第一和第二工作电极来测量附加分析物或非分析物相关信号。 这样的测量可以提供用于处理传感器数据的背景和/或灵敏度测量，并且可以用于触发诸如数据的数字滤波或暂停显示数据的事件。
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公开(公告)号：US20080242961A1
公开(公告)日：2008-10-02
申请号：US12137396
申请日：2008-06-11
申请人： Mark Brister , Peter C. Simpson , James H. Brauker
发明人： Mark Brister , Peter C. Simpson , James H. Brauker
IPC分类号： A61B5/05
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/14514 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B2560/0223
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号：US09986942B2
公开(公告)日：2018-06-05
申请号：US11503367
申请日：2006-08-10
申请人： James H. Brauker , Robert Boock , Monica Rixman , Peter C. Simpson , Mark Brister , Mark Shults
发明人： James H. Brauker , Robert Boock , Monica Rixman , Peter C. Simpson , Mark Brister , Mark Shults
IPC分类号： A61B5/1486 , A61B5/1473 , G01N33/66 , A61B5/145 , A61B5/00 , C12Q1/00 , G01N33/543
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1473 , A61B5/411 , A61B5/418 , A61B5/6848 , A61B2562/08 , C12Q1/006 , G01N33/54366 , G01N33/66 , Y02A50/55 , Y02A50/58
摘要： Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.
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公开(公告)号：US08298142B2
公开(公告)日：2012-10-30
申请号：US12267547
申请日：2008-11-07
申请人： Peter C. Simpson , Michael J. Estes , Paul V. Neale , Robert Boock , Jacob S. Leach , Richard C. Yang , Mark Brister
发明人： Peter C. Simpson , Michael J. Estes , Paul V. Neale , Robert Boock , Jacob S. Leach , Richard C. Yang , Mark Brister
CPC分类号： C12Q1/001 , A61B5/0031 , A61B5/145 , A61B5/14532 , A61B5/14539 , A61B5/14542 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/412 , A61B5/4839 , A61B5/6848 , A61B5/6849 , A61B5/7275 , A61B5/743 , A61B2560/0223 , A61B2560/04 , A61B2562/085 , A61M5/14 , A61M5/16804 , A61M5/1723 , A61M25/007 , A61M2005/14296 , A61M2230/201 , C12Q1/006 , G06F19/3468 , G16H40/40 , Y02A90/26
摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
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