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58 条记录 (耗时 0.024 秒)

    Benzothiazolinone compounds
    46.
    发明授权
    Benzothiazolinone compounds 失效
    苯并噻唑啉酮化合物

    公开(公告)号：US5240949A

    公开(公告)日：1993-08-31

    申请号：US858933

    申请日：1992-03-27

    申请人： Daniel Lesieur ,  Charles Lespagnol ,  Said Yous

    发明人： Daniel Lesieur ,  Charles Lespagnol ,  Said Yous

    IPC分类号： C07D277/68

    CPC分类号： C07D277/68

    摘要： Compounds of general formula (I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group,R.sub.2 represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted thienyl, furyl, pyrrolyl or pyridinyl group,X represents a hydrogen atom,Y represents a hydroxyl group,or else X and Y together represent an oxygen atom, their enantiomers, diastereoisomers and epimers. Medicaments.

    摘要翻译： 通式（I）的化合物：其中：R1表示氢原子或低级烷基，R2表示取代或未取代的烷基，取代或未取代的芳基，取代或未取代的烯基 取代或未取代的噻吩基，呋喃基，吡咯基或吡啶基，X表示氢原子，Y表示羟基，或X或Y一起表示氧原子，它们的对映异构体，非对映异构体和差向异构体。 药剂

    Analgesic benzoxazolinones having at the 6-position a 1-hydroxy-3-morpholinopropyl side chain
    47.
    发明授权
    Analgesic benzoxazolinones having at the 6-position a 1-hydroxy-3-morpholinopropyl side chain 失效
    在6位具有1-羟基-3-吗啉代丙基侧链的镇痛性苯并恶唑啉酮

    公开(公告)号：US5182278A

    公开(公告)日：1993-01-26

    申请号：US737322

    申请日：1991-07-29

    申请人： Daniel Lesieur ,  Charles Lespagnol ,  Jacqueline Bonnet

    发明人： Daniel Lesieur ,  Charles Lespagnol ,  Jacqueline Bonnet

    IPC分类号： C07D263/58 ,  C07D413/06 ,  C07D417/06

    CPC分类号： C07D263/58 ,  C07D413/06 ,  C07D417/06

    摘要： Compounds of general formula (I): ##STR1## in which: R.sub.1 denotes a hydrogen atom or a lower alkyl optionally substituted with a hydroxyl group,R.sub.2 and R.sub.3 :a- identical or different, denote a hydrogen atom, a lower alkyl, a lower alkenyl, a substituted or unsubstituted aryl, a substituted or unsubstituted (lower alkyl)aryl,b- are such that they form, with the nitrogen which carries them, a saturated or unsaturated, mono- or bicyclic heterocyclic system containing at most 3 hetero atoms per ring, substituted or unsubstituted, with the exception of 1-arylpiperazine systems,X denotes a hydrogen atom,Y denotes a hydrogen atom or a hydroxyl,or alternatively X and Y denote an oxygen atom, provided thatR.sub.1 is then other than a methyl group,Z denotes a hydrogen atom or forms a .pi. bond with Y, andT denotes a hydrogen atom or a lower alkyl, their stereoisomers and their quaternary ammonium salts, as well as their addition salts with a pharmaceutically acceptable acid having analgesic or arterial antihypertensive property.Medicinal products.

    摘要翻译： 通式（I）的化合物：其中：R 1表示氢原子或任选被羟基取代的低级烷基，R 2和R 3：a相同或不同，表示氢原子，低级 烷基，低级烯基，取代或未取代的芳基，取代或未取代的（低级烷基）芳基，b-使得它们与携带它们的氮形成饱和或不饱和的单或双环杂环体系，其含有 除了1-芳基哌嗪体系外，每个环上最多3个杂原子是取代或未取代的，X表示氢原子，Y表示氢原子或羟基，或者X和Y表示氧原子，条件是R1为 除甲基外，Z表示氢原子或与Y形成π键，T表示氢原子或低级烷基，它们的立体异构体及其季铵盐，以及它们与药学上可接受的酸的加成盐， 镇痛药或a 镇静抗高血压药物。 药用产品。

    Benzothiazolinone compounds
    50.
    发明授权
    Benzothiazolinone compounds 失效
    苯并噻唑啉酮化合物

    公开(公告)号：US5166353A

    公开(公告)日：1992-11-24

    申请号：US700571

    申请日：1991-05-15

    申请人： Daniel Lesieur ,  Charles Lespagnol ,  Said Yous

    发明人： Daniel Lesieur ,  Charles Lespagnol ,  Said Yous

    IPC分类号： C07D277/68

    CPC分类号： C07D277/68

    摘要： Compounds of general formula(I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group,R.sub.2 represents a substituted or unsubstitutes alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted thienyl, furyl, pyrrolyl or pyridinyl group,X represents a hydrogen atom,Y represents a hydroxyl group,or else X and Y together represent an oxygen atom, their enantiomers, diastereoisomers and epimers. Medicaments.

    摘要翻译： 通式（I）的化合物：其中：R1表示氢原子或低级烷基，R2表示取代或未取代的烷基，取代或未取代的芳基，取代或未取代的烯基 取代或未取代的噻吩基，呋喃基，吡咯基或吡啶基，X表示氢原子，Y表示羟基，或X或Y一起表示氧原子，它们的对映异构体，非对映异构体和差向异构体。 药剂