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公开(公告)号：US20200315792A1
公开(公告)日：2020-10-08
申请号：US16906672
申请日：2020-06-19
Applicant: Edwards Lifesciences Corporation
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
IPC: A61F2/24
Abstract: An implantable prosthetic valve includes a radially collapsible and radially expandable annular frame. The frame includes an annular main body sized to be implanted within a native mitral valve annulus. The frame also includes an atrial sealing member coupled to and extending radially away from the main body. The atrial sealing member is sized to extend over tissue of the native mitral annulus within a left atrium to reduce paravalvular leakage. The atrial sealing member includes an inner zig-zag portion and an outer zig-zag portion. The inner zig-zag portion and the outer zig-zag portion are connected to the main body portion only via a fabric to enhance flexibility of the atrial sealing member relative to the main body. The prosthetic valve also includes a valve member disposed within an interior of the frame.
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公开(公告)号：US10058424B2
公开(公告)日：2018-08-28
申请号：US14830347
申请日：2015-08-19
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander H. Cooper , Matthew A. Peterson
CPC classification number: A61F2/2436 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2002/9665 , A61F2220/0008 , A61F2230/005 , A61F2230/0052 , A61F2230/0067 , A61F2230/0069
Abstract: Embodiments of prosthetic valve frames for implantation within a native mitral valve can include a main body portion, and first and second radially extending flanges coupled to the main body portion. The flanges can be coupled to the main body such that the flanges are spaced father apart from one another when the main body portion is in a crimped configuration than when the main body portion is in an expanded configuration. Associated delivery systems and methods of delivery are provided.
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公开(公告)号：US20170095328A1
公开(公告)日：2017-04-06
申请号：US15382429
申请日：2016-12-16
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander H. Cooper , Matthew A. Peterson , William C. Brunnett
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2436 , A61F2002/9534 , A61F2220/0008 , A61F2230/005 , A61F2230/0065 , A61F2230/0078
Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.
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公开(公告)号：US09532870B2
公开(公告)日：2017-01-03
申请号：US14730639
申请日：2015-06-04
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander H. Cooper , Matthew A. Peterson , William C. Brunnett
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2436 , A61F2002/9534 , A61F2220/0008 , A61F2230/005 , A61F2230/0065 , A61F2230/0078
Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.
Abstract translation: 假体心脏瓣膜的实施例包括环形主体，从主体的心房端径向向外延伸的心房帽以及从主体的心室端向外延伸的多个心室锚。 每个心室锚可以具有连接到心室端的近端部分，中间部分，其远离心房端延伸，然后朝向心房延伸以限定第一弯曲部，以及自由远端部分，其从中间部分 。 远端部分可以包括第一部分，第二部分和在第一和第二部分之间的第二弯曲部分，第一部分从中间部分沿着朝向心房端的方向延伸并且径向远离主体。
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公开(公告)号：US20160051362A1
公开(公告)日：2016-02-25
申请号：US14830347
申请日：2015-08-19
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander H. Cooper , Matthew A. Peterson
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2002/9665 , A61F2220/0008 , A61F2230/005 , A61F2230/0052 , A61F2230/0067 , A61F2230/0069
Abstract: Embodiments of prosthetic valve frames for implantation within a native mitral valve can include a main body portion, and first and second radially extending flanges coupled to the main body portion. The flanges can be coupled to the main body such that the flanges are spaced father apart from one another when the main body portion is in a crimped configuration than when the main body portion is in an expanded configuration. Associated delivery systems and methods of delivery are provided.
Abstract translation: 用于植入在天然二尖瓣内的人造瓣膜的实施例可以包括主体部分，以及联接到主体部分的第一和第二径向延伸的凸缘。 凸缘可联接到主体，使得当主体部分处于卷曲构造时，当主体部分处于展开构型时，凸缘彼此分开。 提供相关的运送系统和运送方式。
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Patent Agency Ranking
公开(公告)号：US20240325144A1
公开(公告)日：2024-10-03
申请号：US18742979
申请日：2024-06-13
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61B6/4441 , A61B8/12 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: A prosthetic heart valve for implantation within a native atrioventricular heart valve. The prosthetic heart valve includes a self-expanding frame having an annular main body and a valve member disposed within the main body. The prosthetic heart valve includes an atrial sealing member formed by a fabric cover and a plurality of arms that are arranged side-by-side in a circumferential direction around the main body. The atrial sealing member extends radially outwardly from the main body and a peripheral portion of the atrial sealing member curves upwardly for conforming to surrounding native anatomy. The prosthetic heart valve further includes one or more ventricular anchors extending from the main body for capturing native leaflet tissue and thereby securing the prosthetic heart valve within the native atrioventricular heart valve.
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公开(公告)号：US20240315835A1
公开(公告)日：2024-09-26
申请号：US18731039
申请日：2024-05-31
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , Jeremy Brent (aka J. Brent) Ratz , Seung-Beom Yi
CPC classification number: A61F2/2409 , A61F2/2418 , A61L27/04 , A61L27/3625 , A61F2/2412 , A61F2/2436 , A61F2220/0008 , A61F2220/0075 , A61F2230/0093 , A61F2250/0018 , A61F2250/0039 , A61F2250/0063 , A61L2430/20
Abstract: A self-expanding prosthetic heart valve includes an inner frame and an outer sealing frame. A lower region of the outer sealing frame is coupled to a lower region of the inner frame. At least a portion of the outer frame has a D-shape cross-section for conforming to a shape of a native heart valve annulus. Elongate anchors are positioned outwardly from the outer sealing frame for anchoring to native leaflets. Preferably, the native leaflets are secured between the anchors and an outer surface of the outer sealing frame. A valve body is positioned within an interior lumen of the inner frame and provides a one-way valve mechanism for replacing the function of the native leaflets. For additional stability, a further anchoring mechanism may extend from the inner frame for attachment to a heart wall. The prosthetic heart valve is well-suited for replacing the function of a native tricuspid valve.
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公开(公告)号：US20240008978A1
公开(公告)日：2024-01-11
申请号：US18371303
申请日：2023-09-21
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Rupesh Gajanan Nawalakhe , Sandip Vasant Pawar , Siddharth Vad , Matthew A. Peterson , David Robert Landon , Zachary Charles VanEvery
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2002/0081
Abstract: A fabric having a honeycomb weave pattern is provided for use with medical implants. The fabric may be heat treated to increase a thickness and texture of the fabric. The fabric may be compliant and compressible for providing cushioning within a patient's body. For example, the fabric may be applied to a prosthetic valve to cushion a portion of the prosthetic heart valve. The fabric may also be textured to provide enhanced friction between the prosthetic heart valve and the surrounding native tissue. Enhanced friction may be achieved by weave patterns or by the inclusion of protrusions or barbs in the fabric.
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公开(公告)号：US20230363906A1
公开(公告)日：2023-11-16
申请号：US18226657
申请日：2023-07-26
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Alexander H. Cooper , Matthew A. Peterson
CPC classification number: A61F2/2436 , A61F2/24 , A61F2/2418 , A61F2230/0052 , A61F2220/0008 , A61F2230/0069 , A61F2002/9665 , A61F2230/0067 , A61F2/2412 , A61F2230/005
Abstract: An assembly includes a delivery apparatus and a self-expandable prosthetic heart valve including radially extendable atrial protrusions and radially extendable ventricular protrusions. The prosthetic valve further includes a valve member supported by an annular body having the atrial protrusions and the ventricular protrusions coupled thereto. The delivery apparatus includes a first (distal) capsule portion and a second (proximal) capsule portion for retaining the prosthetic valve in a radially compressed, delivery state. The first capsule portion can be moved distally to allow the ventricular protrusions to expand, and the second capsule portion can be proximally retracted to allow the atrial protrusions to expand and transition to prosthetic valve to a radially expanded state. When implanted, the atrial protrusions are configured to engage an atrial side of a native heart valve, and the ventricular protrusions are configured to engage the ventricular side of the native heart valve.
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公开(公告)号：US20230046495A1
公开(公告)日：2023-02-16
申请号：US17980384
申请日：2022-11-03
Applicant: Edwards Lifesciences Corporation
Inventor： Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , J. Brent Ratz , Seung-Beom Yi
Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.
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