公开(公告)号：USD981881S1

公开(公告)日：2023-03-28

申请号：US29752023

申请日：2020-09-24

Applicant: Micromass UK Limited

Designer： Matthew J. Henderson ,  Mark W. Towers ,  Gordon Kearney ,  Paul R. Murray ,  Emrys Jones ,  Arthur Blake ,  Andrew Pawson

公开(公告)号：US11454611B2

公开(公告)日：2022-09-27

申请号：US16093506

申请日：2017-04-13

Applicant: Micromass UK Limited

Inventor： Emrys Jones ,  Sara Stead ,  Julia Balog ,  Richard Schafer

IPC: H01J49/00 ,  G01N27/623 ,  G01N33/00 ,  G01N33/68 ,  G01N33/92

Abstract: A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target plant material; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said plant material.

公开(公告)号：US11145497B2

公开(公告)日：2021-10-12

申请号：US16308214

申请日：2017-06-06

Applicant: Micromass UK Limited

Inventor： Steven Pringle ,  Emrys Jones ,  Mike Morris ,  Keith Richardson ,  Zoltan Takats

IPC: H01J49/00 ,  A61B5/00 ,  G01N21/71 ,  G01N27/622 ,  H01J49/16 ,  A61B1/313 ,  A61B18/00

Abstract: A method of analysing a target is disclosed comprising ablating a portion of a target so as to cause an aerosol plume to be produced and light or other electromagnetic radiation to be emitted. The aerosol plume is analysed using mass spectrometry and/or ion mobility spectrometry and the emitted light or other electromagnetic radiation is analysed using optical spectroscopy in order to determine one or more regions of interest of the target and/or one or more margins or bounds of a region of interest of the target.

公开(公告)号：US11133169B2

公开(公告)日：2021-09-28

申请号：US16306821

申请日：2017-06-05

Applicant: MICROMASS UK LIMITED

Inventor： Emrys Jones ,  Richard Chapman ,  Steven Pringle

IPC: H01J49/00 ,  H01J49/14 ,  H01J49/16

Abstract: Apparatus is disclosed comprising a first ion source (210) arranged and adapted to emit a spray of charged droplets (211) and a detector or sensor (203) arranged and adapted automatically to detect, sense or determine one or more first parameters or properties of the spray of charged droplets (211) as the spray of charged droplets (211) impacts upon a surface of the detector or sensor 203. The apparatus further comprises a control system (204) arranged and adapted to adjust, correct and/or optimise one or more second parameters or properties of the spray of charged droplets (211) based on the one or more first parameters or properties of the spray of charged droplets (211) detected, sensed or determined by the detector or sensor (203).

公开(公告)号：US11031221B2

公开(公告)日：2021-06-08

申请号：US15555758

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Emrys Jones ,  Tamas Karancsi ,  Steven Derek Pringle ,  Julia Balog ,  Daniel Simon ,  Lajos Godorhazy ,  Daniel Szalay ,  Zoltan Takats

IPC: H01J49/00 ,  H01J49/04 ,  A61B10/02 ,  A61B17/32 ,  A61B18/00 ,  A61B18/14 ,  A61B18/20 ,  G01N3/00 ,  G01N9/00 ,  G01N33/68 ,  H01J49/06 ,  H01J49/16 ,  A61B90/13 ,  A61B1/04 ,  A61B1/273 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0507 ,  A61B5/055 ,  A61B6/03 ,  A61B8/13 ,  A61B10/00 ,  A61B17/00 ,  A61B18/04 ,  A61B18/18 ,  A61F13/38 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/22 ,  G01N27/622 ,  G01N27/624 ,  G01N30/72 ,  G01N33/487 ,  G01N33/92 ,  H01J49/02 ,  H01J49/10 ,  H01J49/14 ,  H01J49/24 ,  H01J49/26 ,  G16B20/00 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  A61B1/00 ,  A61B1/31 ,  A61B5/145 ,  G06F19/00

Abstract: A method of mass spectrometry or ion mobility spectrometry is disclosed comprising: providing an analyte; supplying a matrix compound to said analyte such that said analyte dissolves in said matrix; forming first droplets of the dissolved analyte; and colliding said first droplets with a collision surface. The use of matrix improves the analyte ion signal.

公开(公告)号：US20190304768A1

公开(公告)日：2019-10-03

申请号：US16306809

申请日：2017-06-05

Applicant: MICROMASS UK LIMITED

Inventor： Emrys Jones ,  Richard Chapman ,  Steven Derek PRINGLE

IPC: H01J49/16 ,  H01J49/14 ,  H01J49/28 ,  H01J49/00

Abstract: A method of analysing a sample is disclosed that comprises surveying a sample in a first mode of operation by directing a spray of charged droplets onto the sample, determining one or more regions of interest in the sample, and analysing the one or more regions of interest in a second different mode of operation by directing a spray of charged droplets onto the sample. The spot size of the spray of charged droplets at a point of impact with the sample may be varied.

公开(公告)号：US20190198307A1

公开(公告)日：2019-06-27

申请号：US16306821

申请日：2017-06-05

Applicant: MICROMASS UK LIMITED

Inventor： Emrys Jones ,  Richard Chapman ,  Steven PRINGLE

IPC: H01J49/14 ,  H01J49/00 ,  H01J49/16

CPC classification number: H01J49/142 ,  H01J49/0004 ,  H01J49/0009 ,  H01J49/0031 ,  H01J49/165

Abstract: Apparatus is disclosed comprising a first ion source (210) arranged and adapted to emit a spray of charged droplets (211) and a detector or sensor (203) arranged and adapted automatically to detect, sense or determine one or more first parameters or properties of the spray of charged droplets (211) as the spray of charged droplets (211) impacts upon a surface of the detector or sensor 203. The apparatus further comprises a control system (204) arranged and adapted to adjust, correct and/or optimise one or more second parameters or properties of the spray of charged droplets (211) based on the one or more first parameters or properties of the spray of charged droplets (211) detected, sensed or determined by the detector or sensor (203).