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公开(公告)号:US20070166796A1
公开(公告)日:2007-07-19
申请号:US11539554
申请日:2006-10-06
申请人: Scott Presnell , James West , Julia Novak
发明人: Scott Presnell , James West , Julia Novak
CPC分类号: C07K14/54 , A61K38/00 , C07K14/7155 , C07K2319/00 , C12N2799/026
摘要: The polypeptides, and the polynucleotides encoding for them, described herein are IL-21 antagonists that bind with specificity and exhibit an EC50 that is not detectable in receptor binding studies. These molecules have mutations in the D helix of the IL-21 molecule, and can be used to inhibit the activity of IL-21 with its cognate receptor.
摘要翻译: 本文所述的多肽和编码它们的多核苷酸是与特异性结合并显示在受体结合研究中不可检测的EC 50的IL-21拮抗剂。 这些分子在IL-21分子的D螺旋中具有突变,并且可用于以其同源受体抑制IL-21的活性。
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公开(公告)号:US20060204142A1
公开(公告)日:2006-09-14
申请号:US11088877
申请日:2005-03-25
申请人: James West , Michael Fischer
发明人: James West , Michael Fischer
CPC分类号: G06F16/9535 , G06F16/951
摘要: A method is provided for determining a ranking score for an image or group of related images among a plurality of images accessible by a search engine, such that the ranking score is usable to determine the order in which the images are presented in the results of a search conducted by the search engine. The method comprises monitoring the number of times the image (or the images in the group of related images) is presented for viewing by predetermined users in the results of searches conducted by the search engine. The level of active interest shown by the predetermined users in the image or images presented for viewing in the search results is then monitored, for example by determining the number of times that users select a thumbnail of the image for viewing on an enlarged scale. Finally a ranking score is assigned to the image or images based on the monitored level of active interest as a proportion of the number of times the image or images are presented for viewing by the predetermined users. This then enables an identified set of images to be ordered in such a manner as to take into account the ranking scores of the images, in order to enable users to access the images that they require more quickly and conveniently.
摘要翻译: 提供了一种用于确定由搜索引擎可访问的多个图像中的图像或相关图像组的排名分数的方法,使得排名分数可用于确定图像的结果中呈现图像的顺序 搜索引擎进行搜索。 该方法包括监视由搜索引擎执行的搜索结果中的预定用户呈现图像(或相关图像组中的图像)以供观看的次数。 然后,例如通过确定用户选择用于以放大比例观看的图像的缩略图的次数来监视由用于在搜索结果中观看的图像中的预定用户所示的主动感兴趣程度或用于观看的图像。 最后,基于所监视的主动感兴趣的水平,将图像或图像分配给图像或图像,作为图像或图像呈现以供预定用户观看的次数的一部分。 这样就可以以所考虑的图像的排名得分的方式来排列所识别的一组图像,以便使用户能够更快速方便地访问他们需要的图像。
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公开(公告)号:US20060186801A1
公开(公告)日:2006-08-24
申请号:US11064236
申请日:2005-02-22
申请人: James West
发明人: James West
CPC分类号: H01L51/5262 , G02B6/0025 , G02B6/0036 , H01L51/5268 , H01L51/5271 , H01L51/5275 , Y10S428/917
摘要: A light source includes a first waveguide. The first waveguide includes a light emitting material having a first index of refraction and at least one layer is disposed over the light emitting material. The at least one layer has a second index of refraction and the first index of refraction is greater than the second index of refraction. The light source also includes a second waveguide, which is coupled to the first waveguide. The light emitting device also includes a light extraction structure.
摘要翻译: 光源包括第一波导。 第一波导包括具有第一折射率的发光材料,并且至少一层设置在发光材料上。 所述至少一层具有第二折射率,并且所述第一折射率大于所述第二折射率。 光源还包括耦合到第一波导的第二波导。 发光装置还包括光提取结构。
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公开(公告)号:US20050179890A1
公开(公告)日:2005-08-18
申请号:US10935459
申请日:2004-09-07
申请人: Peter Cramer , James West , Robert Bridges
发明人: Peter Cramer , James West , Robert Bridges
CPC分类号: G01C15/002 , G01B11/002 , G01S7/4811 , G01S7/4813 , G01S7/497 , G01S17/42 , G01S17/66 , G02B5/122
摘要: An apparatus and method for compensating a coordinate measurement machine is provided, which may be a laser-based coordinate measurement machine, laser tracker, or other coordinate measurement device. In one exemplary method, such compensation comprises self-compensation of payload parameters by means of embedded tracker targets. In another exemplary embodiment, such compensation comprises self-compensation of payload, azimuth-post, axis, or R0 parameters by means of embedded temperature sensors.
摘要翻译: 提供了一种用于补偿坐标测量机的装置和方法,其可以是基于激光的坐标测量机,激光跟踪器或其他坐标测量装置。 在一个示例性方法中,这种补偿包括借助于嵌入式跟踪器目标的有效载荷参数的自我补偿。 在另一示例性实施例中,这种补偿包括通过嵌入式温度传感器对有效载荷,方位角,轴或R0参数进行自补偿。
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公开(公告)号:US20050159358A1
公开(公告)日:2005-07-21
申请号:US11021088
申请日:2004-12-22
申请人: Zeren Gao , Charles Hart , Christopher Piddington , Paul Sheppard , Kimberly Shoemaker , Debra Gilbertson , James West
发明人: Zeren Gao , Charles Hart , Christopher Piddington , Paul Sheppard , Kimberly Shoemaker , Debra Gilbertson , James West
IPC分类号: A61K38/00 , A61K38/18 , C07K14/475 , C07K14/52 , C07H21/04
CPC分类号: C07K14/52 , A01K2217/05 , A61K38/1858 , C07K14/475 , C12N2799/022
摘要: Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
摘要翻译: 公开了多肽生长因子,其制备方法,编码它们的多核苷酸,针对它们的抗体以及使用它们的方法。 所述多肽包含与SEQ ID NO:2的残基46-163或SEQ ID NO:2的残基235-345至少90%相同的氨基酸区段。 还公开了多肽的多聚体。 多肽,多聚体蛋白和多核苷酸可用于细胞和组织发育的研究和调节,作为细胞培养基的组分和诊断剂。
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公开(公告)号:US20050063099A1
公开(公告)日:2005-03-24
申请号:US10832454
申请日:2004-04-27
申请人: James West , David Callaghan
发明人: James West , David Callaghan
CPC分类号: G11B15/62 , G11B33/1446
摘要: A magnetic tape drive includes a head assembly comprising a read and/or write head mounted for movement along at least one guide rail. A rail cleaner cleans at least a portion of the rail. The cleaner moves along the rail with the head assembly.
摘要翻译: 磁带驱动器包括头部组件,其包括安装成沿着至少一个导轨移动的读取和/或写入头部。 轨道清洁器清洁轨道的至少一部分。 清洁剂沿着轨道与头部组件移动。
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公开(公告)号:US4167984A
公开(公告)日:1979-09-18
申请号:US850135
申请日:1977-11-10
申请人: Ronald W. Hottes , James West
发明人: Ronald W. Hottes , James West
摘要: An apparatus for frictionally engaging and driving a rotatable wheel of a lightweight vehicle is disclosed. The apparatus has a pivotable handle which is movable between a first and a second position. In the first position the handle blocks access to a fuel tank while permitting operation of the engine and engagement of a driven friction surface with the rotatable wheel. In the second position of the handle, the engine is inoperable, the fuel tank may be refilled, and the friction surface cannot engage the rotatable wheel. Preferably, the handle provides means for pivoting the engine to and from a position in which the friction surface engages the rotatable wheel and for operationally engaging an electrical switch to control operation of the engine.
摘要翻译: 公开了一种用于摩擦接合和驱动轻型车辆的可旋转车轮的装置。 该装置具有可在第一和第二位置之间移动的可枢转手柄。 在第一位置,手柄阻挡进入燃料箱,同时允许发动机的操作和从动摩擦表面与可旋转轮的啮合。 在手柄的第二位置,发动机不可操作,燃料箱可以被重新填充,并且摩擦表面不能接合可旋转轮。 优选地,手柄提供用于将发动机枢转到摩擦表面接合可旋转轮的位置并且用于操作地接合电开关以控制发动机的操作的装置。
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公开(公告)号:US08484975B2
公开(公告)日:2013-07-16
申请号:US12026203
申请日:2008-02-05
申请人: James West , Sam Draper
发明人: James West , Sam Draper
CPC分类号: F01K23/101 , Y02E20/16
摘要: A power plant is provided which includes a gas turbine having a compressor for producing compressed air and a combustor for combusting the compressed air with a combustible fuel to produce a heated combustion gas. The power plant also includes a heat recovery steam generator for generating a flow of steam from an exhaust of the gas turbine and a steam turbine for expanding the flow of steam from the heat recovery steam generator. The steam turbine has a rotor having a rotor bore disposed axially therein. The power plant also includes a conduit for directing at least a portion of the compressed air or at least a portion of the heated combustion gas from the gas turbine to the rotor bore of the steam turbine, wherein the compressed air or the heated combustion gas may warm the rotor bore of the steam turbine.
摘要翻译: 提供一种发电厂,其包括具有用于产生压缩空气的压缩机的燃气轮机和用可燃燃料燃烧压缩空气以产生加热的燃烧气体的燃烧器。 发电厂还包括热回收蒸汽发生器,用于从燃气轮机的排气产生蒸汽流,以及蒸汽涡轮机,用于扩大来自热回收蒸汽发生器的蒸汽流。 蒸汽轮机具有转子,该转子具有轴向设置在其中的转子孔。 发电厂还包括用于将至少一部分压缩空气或至少一部分加热的燃烧气体从燃气涡轮引导到蒸汽轮机的转子孔的导管,其中压缩空气或加热的燃烧气体可以 加热蒸汽轮机的转子孔。
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公开(公告)号:US20120157794A1
公开(公告)日:2012-06-21
申请号:US12973863
申请日:2010-12-20
申请人: Robert Goodwin , Erik Jansen , Mark Tuacher , James West , David Burgett , Jeff Anderson , Duane Radmar
发明人: Robert Goodwin , Erik Jansen , Mark Tuacher , James West , David Burgett , Jeff Anderson , Duane Radmar
CPC分类号: A61M16/0666 , A61B5/0826 , A61B5/14551 , A61B5/4818 , A61M11/005 , A61M16/0069 , A61M16/0683 , A61M16/1045 , A61M16/1055 , A61M16/107 , A61M16/16 , A61M2016/0027 , A61M2205/3365 , A61M2205/3673 , A61M2205/42 , A61M2205/50 , A61M2205/8206 , A61M2205/8237 , A61M2205/8262 , A61M2209/086 , A61M2209/088 , A61M2209/10 , A61M2230/005 , A61M2230/06 , A61M2230/205
摘要: Methods, apparatus, and systems for an airflow system, wherein the positive applied pressure is maintained at an approximately constant level over a variety of conditions. In one embodiment, a laminar flow is maintained by a foam housing and configuration. The use low air volume is enabled by using a closed system, wherein feedback information from the system is used to control the speed of an impeller. In one embodiment, moisture recirculation and recycling is applied to extract moisture from exhalation and inject the moisture back into the inhalation portion of the breathing cycle.
摘要翻译: 用于气流系统的方法,装置和系统,其中正施加的压力在各种条件下保持在近似恒定的水平。 在一个实施例中,通过泡沫壳体和构造维持层流。 通过使用封闭系统来实现使用低空气体积,其中使用来自系统的反馈信息来控制叶轮的速度。 在一个实施方案中,施用水分再循环和回收以从呼气中提取水分并将水分注入呼吸循环的吸入部分。
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公开(公告)号:US20080100824A1
公开(公告)日:2008-05-01
申请号:US11969566
申请日:2008-01-04
申请人: Peter Cramer , James West , Robert Bridges
发明人: Peter Cramer , James West , Robert Bridges
IPC分类号: G01C25/00
CPC分类号: G01C15/002 , G01B11/002 , G01S7/4811 , G01S7/4813 , G01S7/497 , G01S17/42 , G01S17/66 , G02B5/122
摘要: An apparatus and method for compensating a coordinate measurement machine is provided, which may be a laser-based coordinate measurement machine, laser tracker, or other coordinate measurement device. In one exemplary method, such compensation comprises self-compensation of payload parameters by means of embedded tracker targets. In another exemplary embodiment, such compensation comprises self-compensation of payload, azimuth-post, axis, or R0 parameters by means of embedded temperature sensors.
摘要翻译: 提供了一种用于补偿坐标测量机的装置和方法,其可以是基于激光的坐标测量机,激光跟踪器或其他坐标测量装置。 在一个示例性方法中,这种补偿包括借助于嵌入式跟踪器目标的有效载荷参数的自我补偿。 在另一示例性实施例中,这种补偿包括通过嵌入式温度传感器对有效载荷,方位角,轴或R0参数进行自补偿。
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