公开(公告)号：US07993862B2

公开(公告)日：2011-08-09

申请号：US12467801

申请日：2009-05-18

申请人： David Allen Elsemore ,  Laurie A. Flynn ,  Michael Crawford

发明人： David Allen Elsemore ,  Laurie A. Flynn ,  Michael Crawford

IPC分类号： G01N33/53

CPC分类号： C12Q1/6888 ,  C07K14/4354 ,  C07K16/18 ,  G01N33/5308

摘要： Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

摘要翻译： 本文公开了用于检测哺乳动物样品中蛔虫存在或不存在的方法，装置，试剂盒和组合物。 本发明的方法，装置，试剂盒和组合物可以用于确认来自哺乳动物的粪便样品中是否存在蛔虫，所述蛔虫样品也可能被钩虫，鞭虫和心丝虫中的一种或多种感染。 可以确认哺乳动物中蛔虫的存在或不存在，例如，为了选择治疗哺乳动物和/或为了确定哺乳动物是否已经在治疗后已经除去感染的目的的最佳方法 已经启动

公开(公告)号：US20090286230A1

公开(公告)日：2009-11-19

申请号：US12467820

申请日：2009-05-18

申请人： David Allen Elsemore ,  Laurie A. Flynn ,  Michael Crawford

发明人： David Allen Elsemore ,  Laurie A. Flynn ,  Michael Crawford

IPC分类号： C12Q1/70 ,  C07K14/435 ,  C07K16/18 ,  G01N33/569

CPC分类号： C07K16/18 ,  C07K14/43536 ,  G01N33/5308

摘要： Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

摘要翻译： 本文公开了用于检测粪便样品中蛔虫存在或不存在的方法，装置，试剂盒和组合物。 本发明的方法，装置，试剂盒和组合物可以用于确认来自哺乳动物的粪便样品中是否存在蛔虫，所述蛔虫样品也可能被钩虫，鞭虫和心丝虫中的一种或多种感染。 可以确认哺乳动物中蛔虫的存在或不存在，例如，为了选择治疗哺乳动物和/或为了确定哺乳动物是否已经在治疗后已经除去感染的目的的最佳方法 已经启动

公开(公告)号：US20090286228A1

公开(公告)日：2009-11-19

申请号：US12467801

申请日：2009-05-18

申请人： David Allen Elsemore ,  Laurie A. Flynn ,  Michael Crawford

发明人： David Allen Elsemore ,  Laurie A. Flynn ,  Michael Crawford

IPC分类号： C12Q1/70 ,  C07K14/00 ,  C07K16/18 ,  C12M1/00 ,  G01N33/53

CPC分类号： C12Q1/6888 ,  C07K14/4354 ,  C07K16/18 ,  G01N33/5308

摘要： Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

摘要翻译： 本文公开了用于检测哺乳动物样品中蛔虫存在或不存在的方法，装置，试剂盒和组合物。 本发明的方法，装置，试剂盒和组合物可以用于确认来自哺乳动物的粪便样品中是否存在蛔虫，所述蛔虫样品也可能被钩虫，鞭虫和心丝虫中的一种或多种感染。 可以确认哺乳动物中蛔虫的存在或不存在，例如，为了选择治疗哺乳动物和/或为了确定哺乳动物是否已经在治疗后已经除去感染的目的的最佳方法 已经启动

公开(公告)号：US20060142419A1

公开(公告)日：2006-06-29

申请号：US11251259

申请日：2005-10-14

申请人： Jingjing Xu ,  Charles Molnar ,  Shekhar Subramoney ,  Michael Crawford ,  John Gergely ,  Lu Zhang ,  Edwin Marston

发明人： Jingjing Xu ,  Charles Molnar ,  Shekhar Subramoney ,  Michael Crawford ,  John Gergely ,  Lu Zhang ,  Edwin Marston

IPC分类号： C09D11/00 ,  C09D5/00

CPC分类号： C08F2/44 ,  C08K3/08 ,  C08K9/02 ,  C09D7/67 ,  C09D7/68 ,  C09D7/69 ,  C09D7/70 ,  C09D11/101 ,  H01F1/0054 ,  H01F1/0063

摘要： The present invention is a dispersion composition comprising (1) a curable mixture of monomers, oligomers, or a combination thereof; and (2) superparamagnetic particles dispersed in the mixture of part (1) and a method for preparing such superparamagnetic particles. The composition of the present invention can be useful as a tool for detecting and/or deterring theft, counterfeiting, or the like in commercial transactions.

摘要翻译： 本发明是一种分散组合物，其包含（1）单体，低聚物或其组合的可固化混合物; 和（2）分散在部分（1）的混合物中的超顺磁性颗粒和制备这种超顺磁性颗粒的方法。 本发明的组合物可用作在商业交易中检测和/或阻止盗窃，假冒等的工具。

公开(公告)号：US20060135671A1

公开(公告)日：2006-06-22

申请号：US11014017

申请日：2004-12-16

申请人： Junling Zhao ,  Michael Crawford ,  Aaron Puhala ,  Martin Cohen

发明人： Junling Zhao ,  Michael Crawford ,  Aaron Puhala ,  Martin Cohen

IPC分类号： C08K9/04

CPC分类号： C08L7/00 ,  C08K3/346 ,  C08K3/36 ,  C08L23/16 ,  C08L23/22 ,  C08L23/283 ,  C08L2666/02 ,  C08L2666/08

摘要： This invention relates to a dual phase rubber composition and pneumatic tire with a rubber sidewall thereof, namely a dual phased non-black colored rubber composition composed of a first pre-formed elastomer phase comprised of butyl-type rubber and EPDM rubber containing a dispersion therein of reinforcing filler comprised of a particulate amorphous precipitated silica and a second pre-formed elastomer phase comprised of a nanocomposite of natural rubber containing a dispersion therein of exfoliated clay platelets. Said exfoliated clay platelets may be substantially oriented within the tire sidewall in a parallel direction to each and may also be substantially oriented in an annular direction about the axis of the tire. The tire sidewall rubber composition may contain at least one additional elastomer which may be included in either or both of said elastomer phases. Such tire sidewall rubber composition may contain a non-black colorant pigment, such as for example a white colored titanium dioxide pigment. The dual phased tire sidewall rubber composition is prepared by a phase mixing process comprised of pre-blending said butyl-type rubber and EPDM rubber together with said precipitated silica reinforcing filler to form a pre-mix thereof, and thereafter mixing therewith said nanocomposite as a pre-formed blend of natural rubber and exfoliated clay platelets.

公开(公告)号：US20050113502A1

公开(公告)日：2005-05-26

申请号：US10917620

申请日：2004-08-13

申请人： Jennifer Fitzharris Wall ,  Bina Botts ,  George Balogh ,  Leonard Reiter ,  Michael Crawford

发明人： Jennifer Fitzharris Wall ,  Bina Botts ,  George Balogh ,  Leonard Reiter ,  Michael Crawford

IPC分类号： B60C19/12 ,  B29C73/16 ,  B29C73/22 ,  B29D30/00 ,  B29D30/06 ,  C08K3/04 ,  C08K3/26 ,  C08K3/34 ,  C08L21/00 ,  C09K3/12

CPC分类号： B29D30/0685 ,  B29C73/163 ,  B29C73/22 ,  B29D30/0061 ,  B29D2030/069 ,  B29L2030/00 ,  Y10T152/10495 ,  Y10T152/10666 ,  Y10T152/10684

摘要： The present invention relates to a pneumatic tire with a built-in sealant layer having a color other than black. The sealant layer is derived from a sealant precursor layer comprised of a butyl rubber, organoperoxide and silica together with a colorant. The butyl rubber-based precursor sealant layer is built into the tire to form a tire assembly and its butyl rubber component is depolymerized during a subsequent curing of the tire at an elevated temperature in a suitable mold to form the tire having the resultant built-in colored sealant layer. The sealant precursor composition may additionally contain clay and/or calcium carbonate.

摘要翻译： 本发明涉及具有不同于黑色的内置密封剂层的充气轮胎。 密封剂层来源于由丁基橡胶，有机过氧化物和二氧化硅以及着色剂组成的密封剂前体层。 将丁基橡胶基前体密封剂层内置在轮胎中以形成轮胎组件，并且其丁基橡胶组分在随后在合适的模具中在升高的温度下固化时解聚，以形成具有所得内置物的轮胎 着色密封层。 密封剂前体组合物可另外含有粘土和/或碳酸钙。

公开(公告)号：US09482511B2

公开(公告)日：2016-11-01

申请号：US13555108

申请日：2012-07-21

申请人： Michael Minneman ,  Jason Ensher ,  Michael Crawford ,  Thomas Milner

发明人： Michael Minneman ,  Jason Ensher ,  Michael Crawford ,  Thomas Milner

IPC分类号： G01B9/02

CPC分类号： G01B9/02004 ,  G01B9/02009 ,  G01B9/02082 ,  G01B9/02087 ,  G01B9/02091

摘要： A system and method for sweeping electromagnetic radiation over a first coherence length and a second length over a range of wavelengths to generate an image. Electromagnetic radiation having a first coherence length is generated and swept over a range of wavelengths. Electromagnetic radiation having a second coherence length is generated and swept over a range of wavelengths. The electromagnetic radiation is splitting through a reference path and a sample path; Electromagnetic radiation returned from the reference path and the sample path is detected, wherein the detector generates output signals corresponding to the received electromagnetic radiation. In one embodiment, the output signals are processed to generate an image. The image may be interleaved with data corresponding to the electromagnetic radiation having the first coherence length and the second coherence length.

摘要翻译： 一种用于在波长范围上的第一相干长度和第二长度扫描电磁辐射以产生图像的系统和方法。 产生具有第一相干长度的电磁辐射并扫过波长范围。 产生具有第二相干长度的电磁辐射并扫过波长范围。 电磁辐射通过参考路径和采样路径分裂; 检测从参考路径返回的电磁辐射和采样路径，其中检测器产生对应于所接收的电磁辐射的输出信号。 在一个实施例中，输出信号被处理以产生图像。 图像可以与对应于具有第一相干长度和第二相干长度的电磁辐射的数据进行交织。

公开(公告)号：US09455549B2

公开(公告)日：2016-09-27

申请号：US14344826

申请日：2012-09-13

申请人： Michael Minneman ,  Jason Ensher ,  Michael Crawford

发明人： Michael Minneman ,  Jason Ensher ,  Michael Crawford

IPC分类号： H01S5/0687 ,  H01S5/0625 ,  H01S5/065 ,  H01S5/068 ,  H01S5/10 ,  H01S5/12 ,  H01S5/125 ,  H01S5/06

CPC分类号： H01S5/0687 ,  H01S5/0617 ,  H01S5/06256 ,  H01S5/0654 ,  H01S5/06804 ,  H01S5/06808 ,  H01S5/1092 ,  H01S5/1209 ,  H01S5/125 ,  H01S2301/163

摘要： A method for sweeping an electromagnetic radiation source (12) to produce single mode operation having an optimized side-mode suppression ratio over a continuous range of wavelengths within a prescribed temporal profile, the electromagnetic radiation source is configured to output electromagnetic radiation at a given wavelength based upon parameters. The method includes determining a set of parameter combinations that satisfy a condition for a desired set of wavelengths and a maximum side mode suppression ratio over the range of wavelengths. The set of parameter combinations define sub-paths for transitioning from one wavelength to another wavelength. Combinations of select sub-paths provide a multivariate path for transitioning over the range of wavelengths. The method also includes controlling the semiconductor laser to emit electromagnetic radiation over the range of wavelengths by traversing the multivariate path in a desired manner.

摘要翻译： 一种用于扫描电磁辐射源（12）以产生具有在规定时间曲线内的连续波长范围内的优化侧模抑制比的单模操作的方法，电磁辐射源被配置为输出给定波长的电磁辐射 基于参数。 该方法包括确定在波长范围内满足所需波长组合的条件和最大侧面模式抑制比的一组参数组合。 该组参数组合定义了从一个波长转换到另一个波长的子路径。 选择子路径的组合提供了用于在波长范围上转变的多变量路径。 该方法还包括通过以期望的方式遍历多变量路径来控制半导体激光器在波长范围上发射电磁辐射。

公开(公告)号：US20140341244A1

公开(公告)日：2014-11-20

申请号：US14344826

申请日：2012-09-13

申请人： Michael Minneman ,  Jason Ensher ,  Michael Crawford

发明人： Michael Minneman ,  Jason Ensher ,  Michael Crawford

IPC分类号： H01S5/0687 ,  H01S5/10 ,  H01S5/12 ,  H01S5/068 ,  H01S5/125

CPC分类号： H01S5/0687 ,  H01S5/0617 ,  H01S5/06256 ,  H01S5/0654 ,  H01S5/06804 ,  H01S5/06808 ,  H01S5/1092 ,  H01S5/1209 ,  H01S5/125 ,  H01S2301/163

摘要： A method for sweeping an electromagnetic radiation source (12) to produce single mode operation having an optimized side-mode suppression ratio over a continuous range of wavelengths within a prescribed temporal profile, the electromagnetic radiation source is configured to output electromagnetic radiation at a given wavelength based upon parameters. The method includes determining a set of parameter combinations that satisfy a condition for a desired set of wavelengths and a maximum side mode suppression ratio over the range of wavelengths. The set of parameter combinations define sub-paths for transitioning from one wavelength to another wavelength. Combinations of select sub-paths provide a multivariate path for transitioning over the range of wavelengths. The method also includes controlling the semiconductor laser to emit electromagnetic radiation over the range of wavelengths by traversing the multivariate path in a desired manner.

摘要翻译： 一种用于扫描电磁辐射源（12）以产生具有在规定时间曲线内的连续波长范围内的优化侧模抑制比的单模操作的方法，电磁辐射源被配置为输出给定波长的电磁辐射 基于参数。 该方法包括确定在波长范围内满足所需波长组合的条件和最大侧面模式抑制比的一组参数组合。 该组参数组合定义了从一个波长转换到另一个波长的子路径。 选择子路径的组合提供了用于在波长范围上转变的多变量路径。 该方法还包括通过以期望的方式遍历多变量路径来控制半导体激光器在波长范围上发射电磁辐射。

公开(公告)号：US08873066B2

公开(公告)日：2014-10-28

申请号：US13182780

申请日：2011-07-14

申请人： Jason Ensher ,  Michael Minneman ,  Michael Crawford

发明人： Jason Ensher ,  Michael Minneman ,  Michael Crawford

IPC分类号： G01B11/02 ,  G01B9/02

CPC分类号： G01B9/02004 ,  G01B9/02005 ,  G01B9/02007 ,  G01B9/02069 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70

摘要： A system and method for measuring an interferometric signal from a swept-wavelength interferometer by scanning a tunable laser source over two wavelength ranges, whose centers are separated substantially more than the length of wavelength ranges. The spatial resolution of the measurement is determined by the inverse of the wavelength separation between a first and second wavelength region, as well as by the wavelength range of the first and second regions. An electronically tunable laser may be utilized to produce two wavelength ranges that are widely separated in wavelength. Such a system and method has wide applications to the fields of optical frequency domain reflectometry (OFDR) and swept-wavelength optical coherence tomography (OCT), for example.

摘要翻译： 一种用于通过在两个波长范围上扫描可调激光源的扫描波长干涉仪来测量干涉信号的系统和方法，其中心基本上大于波长范围的长度。 测量的空间分辨率由第一和第二波长区域之间的波长间隔以及第一和第二区域的波长范围的倒数决定。 可以使用电子可调激光器来产生波长广泛分离的两个波长范围。 例如，这种系统和方法在光频域反射测量（OFDR）和扫描波长光学相干断层扫描（OCT）领域具有广泛的应用。