摘要:
A process for the preparation of optically active 3-demethylmevalonic acid derivatives of the formula I ##STR1## (3,5-dihydroxy carboxylic acid derivatives) or of the formula II ##STR2## in which R, R.sup.1 and Y have the indicated meanings, is described. The invention furthermore relates to aldehydes of the formula XII ##STR3## in which M represents the indicated protective groups.
摘要:
A carrying axle (1) for trailers and a method for the production thereof are provided. The axle (1) includes an axle body (4) having an outer supporting axle tube (10) in which a rocker arm assembly (6), which is bent once or several times, is introduced. The rocker arm assembly (6) is produced as a metal, tubular stamped and bent single piece. The rocker arm assembly is stamped from a platine (21) or a sheet metal strip (23) and is bent in order to form an angled tube (22).
摘要:
In a metering apparatus for the metered introduction of a first medium into an exhaust gas system of an internal combustion engine, which includes a conditioning apparatus in which also a second medium is introduced via a dispensing apparatus which is connected to the conditioning apparatus and via which the first medium and the second medium are introduced into the exhaust gas system, a supply unit for supplying a third medium, which is different from the second medium in its physical properties and/or its chemical composition, is connected to the conditioning apparatus for cleaning of the conditioning apparatus and the dispensing apparatus from constituent parts of the first medium by the third medium or a mixture of the second and the third medium.
摘要:
The present invention relates to a process for the preparation of chiral, nonracemic compounds of the formula I ##STR1## in which R.sup.1 and R.sup.2 have the meanings indicated in claim 1 and which are useful intermediates for the preparation of pharmaceutical active compounds in which, for resolution, a salt is formed from the racemic compound of the formula I and a chiral, nonracemic amino compound. It furthermore relates to compounds of the formula I and esters thereof.
摘要:
Process for the resolution of rac-2-oxotricyclo�2.2.1.0.sup.3,5 !heptane-7-carboxylic acid esters using lipase from candida.Compounds of the formula I ##STR1## in which R.sup.1 has the meanings mentioned, may be obtained in isomerically pure form from enantiomer mixtures or racemic mixtures by reacting the compound of the formula I in the presence of a lipase or esterase from porcine liver, porcine pancreas, bovine pancreas or from microorganisms such as Candida, Pseudomonas, Mucor, Rhizopus and Aspergillus, or proteases from Bacillus in the presence of water and, if desired, a cosolvent and separating from one another the esters and acids present in the solution obtained.
摘要:
Substituted 3-thia- and 3-oxa-alkylflavones of formula I ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 X, m and n have the indicated meanings, a process for the preparation of these compounds and their use as medicaments and pharmaceutical preparations are described. In addition, new intermediates for the preparation of the compounds of formula I are described.
摘要:
Leukotriene antagonists, processes for the preparation thereof, the use thereof for the treatment of diseases, and precursors.Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and X have the indicated meanings, processes for the preparation of these compounds, the use thereof as pharmaceuticals, and pharmaceutical products based on these compounds are described. In addition, precursors for the preparation of compounds of the formula I are described.
摘要:
Variations in parameters of a waveguide system caused by an excitation of charge carriers of a specimen to be measured and positioned in a microwave field, give definite information on the material properties of the specimen without having to destroy, or even contact the specimen. Irradiation with a sharply focused photon or electron beam of a surface spot having a diameter of about 0.1 to 10.0 micrometers, and displacing of this light spot across the surface of the specimen, with the displacement increments of the specimen within the cross sectional area of a waveguide being of the order of magnitude of micrometers, surface structures such as ground boundaries, steps in stratified-lattice crystals, formation defects, destroyed surface areas, etc., can be detected in photosensitive semiconductor layers with a high resolution.
摘要:
What are disclosed are prostacylin PGI.sub.2 analogs of the formula ##STR1## having a more specific or longer lasting pharmacological action than PGI.sub.2, methods of making these analogs; and methods and pharmaceutical preparations for inhibiting blood platelet aggregation, for treating hypertension, for the treatment or prophylaxis of gastrointestinal ulcers, and for the treatment of asthma.
摘要:
A carrying axle (1) for trailers and a method for the production thereof are provided. The axle (1) includes an axle body (4) having an outer supporting axle tube (10) in which a rocker arm assembly (6), which is bent once or several times, is introduced. The rocker arm assembly (6) is produced as a metal, tubular stamped and bent single piece. The rocker arm assembly is stamped from a platine (21) or a sheet metal strip (23) and is bent in order to form an angled tube (22).