Raman amplifier system and method with integrated optical time domain reflectometer
    43.
    发明授权
    Raman amplifier system and method with integrated optical time domain reflectometer 有权
    具有集成光时域反射计的拉曼放大器系统和方法

    公开(公告)号:US09148710B2

    公开(公告)日:2015-09-29

    申请号:US13622481

    申请日:2012-09-19

    摘要: Raman amplifier systems and methods with an integrated Optical Time Domain Reflectometer (OTDR) for integrated testing functionality include an amplifier system, an OTDR and telemetry subsystem, and a method of operation. The OTDR and telemetry subsystem is configured to operate in an OTDR mode when coupled to a line in port and to operate in a telemetry mode when coupled to a line out port. The OTDR and telemetry subsystem enables on-demand fiber testing while also operating as a telemetry channel that is both a redundant optical service channel (OSC) and provides a mechanism to monitor Raman gain over time. The OTDR and telemetry subsystem minimizes cost and space by sharing major optical and electrical components between the integrated OTDR and other functions on the Raman amplifier.

    摘要翻译: 具有用于集成测试功能的集成光时域反射计(OTDR)的拉曼放大器系统和方法包括放大器系统,OTDR和遥测子系统以及操作方法。 OTDR和遥测子系统配置为在耦合到端口线路时以OTDR模式运行,并且在耦合到线路输出端口时以遥测模式运行。 OTDR和遥测子系统实现了按需光纤测试,同时也作为冗余光学服务通道(OSC)的遥测通道运行,并提供了一种随时间监测拉曼增益的机制。 OTDR和遥测系统通过在集成OTDR和拉曼放大器上的其他功能之间共享主要的光学和电气部件,最大限度地降低成本和空间。

    RAMAN AMPLIFIER SYSTEM AND METHOD WITH INTEGRATED OPTICAL TIME DOMAIN REFLECTOMETER
    44.
    发明申请
    RAMAN AMPLIFIER SYSTEM AND METHOD WITH INTEGRATED OPTICAL TIME DOMAIN REFLECTOMETER 有权
    拉曼放大器系统和方法与集成光时域反射计

    公开(公告)号:US20140077971A1

    公开(公告)日:2014-03-20

    申请号:US13622481

    申请日:2012-09-19

    IPC分类号: G08C23/04

    摘要: Raman amplifier systems and methods with an integrated Optical Time Domain Reflectometer (OTDR) for integrated testing functionality include an amplifier system, an OTDR and telemetry subsystem, and a method of operation. The OTDR and telemetry subsystem is configured to operate in an OTDR mode when coupled to a line in port and to operate in a telemetry mode when coupled to a line out port. The OTDR and telemetry subsystem enables on-demand fiber testing while also operating as a telemetry channel that is both a redundant optical service channel (OSC) and provides a mechanism to monitor Raman gain over time. The OTDR and telemetry subsystem minimizes cost and space by sharing major optical and electrical components between the integrated OTDR and other functions on the Raman amplifier.

    摘要翻译: 具有用于集成测试功能的集成光时域反射计(OTDR)的拉曼放大器系统和方法包括放大器系统,OTDR和遥测子系统以及操作方法。 OTDR和遥测子系统配置为在耦合到端口线路时以OTDR模式运行,并且在耦合到线路输出端口时以遥测模式运行。 OTDR和遥测子系统实现了按需光纤测试,同时也作为冗余光学服务通道(OSC)的遥测通道运行,并提供了一种随时间监测拉曼增益的机制。 OTDR和遥测系统通过在集成OTDR和拉曼放大器上的其他功能之间共享主要的光学和电气部件,最大限度地降低成本和空间。

    Methods and compositions for detecting telomerase activity
    49.
    发明授权
    Methods and compositions for detecting telomerase activity 有权
    检测端粒酶活性的方法和组合物

    公开(公告)号:US07390621B2

    公开(公告)日:2008-06-24

    申请号:US10534978

    申请日:2003-11-12

    IPC分类号: C12Q1/68 C12P19/34

    摘要: A method for determining telomerase activity using primer extension followed with real time PCR quantification is disclosed. The method of the present invention provides a rapid, sensitive and accurate measurement for telomerase activity in a biological sample. In one embodiment, the method includes the steps of: adding the biological sample to a reaction tube containing a first reaction mixture having a first primer and nucleoside triphosphates, a second reaction mixture having a second primer and a DNA polymerase, and a wax layer that separates the first reaction mixture from the second reaction mixture; incubating the biological sample with the first reaction mixture; admixing the extension product with the second reaction mixture; amplifying and quantifying the extension product using real-time PCR and a control template. In another embodiment, the detection method includes an in situ primer extension step that allows the production of the extension product within an intact cell. In this embodiment, the extension product can be preserved under appropriate conditions for an extended time before the completion of the quantification step.

    摘要翻译: 公开了使用引物延伸测定端粒酶活性的方法,随后进行实时PCR定量。 本发明的方法提供对生物样品中端粒酶活性的快速,灵敏和准确的测量。 在一个实施方案中,该方法包括以下步骤:将生物样品加入到含有具有第一引物和核苷三磷酸的第一反应混合物的反应管中,具有第二引物和DNA聚合酶的第二反应混合物和蜡层, 将第一反应混合物与第二反应混合物分离; 用第一反应混合物孵育生物样品; 将延伸产物与第二反应混合物混合; 使用实时PCR扩增和定量扩增产物和对照模板。 在另一个实施方案中,检测方法包括原位引物延伸步骤,其允许在完整细胞内产生延伸产物。 在本实施例中,扩展产品可以在适当的条件下在量化步骤完成之前延长一段时间。

    Optical communication system having dynamic gain equalization
    50.
    发明授权
    Optical communication system having dynamic gain equalization 有权
    具有动态增益均衡的光通信系统

    公开(公告)号:US07075711B2

    公开(公告)日:2006-07-11

    申请号:US10986817

    申请日:2004-11-15

    IPC分类号: H04B10/12 H04J14/00

    CPC分类号: H04B10/296

    摘要: An optical communication device, and related method, are provided for reducing ripple in WDM systems. In particular, the optical communication device includes a dynamic gain equalization (DGE) circuit is coupled to an optical communication path carrying the WDM optical signals. The DGE circuit adjusts the powers associated with each channel on a channel-by-channel basis so that the WDM optical signal has a desired power spectrum. The DGE is controlled in response to sense signals generated by an optical performance monitoring (OPM) circuit located downstream from the DGE or substantially co-located with the DGE. The OPM monitors the WDM spectrum for optical signal power variations and outputs the sense signal when the variations fall outside a given tolerance. Typically, one DGE is associated with a group of concatenated amplifiers so that multiple DGEs are provided in a system having many groups of such amplifiers. Likewise, multiple OPMs are provided in such systems, each corresponding to a respective DGE, so that ripple can be reduced and desired WDM optical signal powers can be achieved in the WDM system.

    摘要翻译: 提供了一种光通信设备及相关方法,用于减少WDM系统中的纹波。 特别地,光通信设备包括动态增益均衡(DGE)电路耦合到承载WDM光信号的光通信路径。 DGE电路在逐个通道的基础上调整与每个通道相关联的功率,使得WDM光信号具有所需的功率谱。 响应由位于DGE下游的光学性能监视(OPM)电路产生的感测信号或与DGE基本上同一位置来控制DGE。 OPM监视WDM频谱的光信号功率变化,并在变化值超出给定公差时输出感测信号。 通常,一个DGE与一组级联放大器相关联,使得在具有许多这种放大器组的系统中提供多个DGE。 类似地,在这样的系统中提供多个OPM,每个对应于相应的DGE,使得纹波可以减少,并且可以在WDM系统中实现期望的WDM光信号功率。