Octacyclodepsipeptides having an endoparasiticidal action
    41.
    发明授权
    Octacyclodepsipeptides having an endoparasiticidal action 失效
    具有内寄生性杀伤作用的Octacyclodepsipeptide

    公开(公告)号:US06369028B1

    公开(公告)日:2002-04-09

    申请号:US08246029

    申请日:1994-05-19

    IPC分类号: A61K3800

    摘要: The present invention relates to compounds of the general formula (I) in which R1, R2, R11 and R12 represent the same or different radicals selected from the group of C1-8-alkyl, C1-8-halogenoalkyl, C3-6-cycloalkyl, aralkyl or aryl, R3, R5, R7, R9, represent the same or different radicals selected from the group of hydrogen or straight-chain C1-5-alkyl or branched C4-7-alkyl which may optionally be substituted by hydroxyl, C1-4-alkoxy, carboxyl  carboxamide,  imidazolyl, indolyl, guanidino, —SH or C1-4-alkylthio, and furthermore represents aryl, aralkyl or heteroarylmethyl which may be substituted by halogen, hydroxyl, C1-4-alkyl, C1-4-alkoxy, nitro or a —NR13R14 group in which R13 and R14 independently from each other represent hydrogen or alkyl or together with the adjoining nitrogen atom forms a 5, 6 or 7-membered ring which is optionally interrupted by O, S or N and which is optionally C1-4-alkyl substituted, R4, R6, R8, R10 represent the same or different radicals selected from the group of hydrogen, straight-chain C1-5-alkyl and represents isopropyl, sec.-butyl, t-butyl, C2-6-alkenyl, C3-7-cycloalkyl, which may optionally be substituted by hydroxyl, C1-4-alkoxy, carboxyl, carboxamide, imidazolyl, indolyl, guanidino, SH or C1-4-alkylthio and represent aryl, aralkyl or heteroarylmethyl which may be substituted by halogen, hydroxyl, C1-4-alkyl, C1-4-alkoxy, and stereoisomers thereof, to processes for their preparation and to their use as endoparasiticides.

    摘要翻译: 本发明涉及通式(I)的化合物,其中R 1,R 2,R 11和R 12表示相同或不同的选自C 1-8 - 烷基,C 1-8 - 卤代烷基,C 3-6 - 环烷基, 芳烷基或芳基,R 3,R 5,R 7,R 9表示相同或不同的选自氢或直链C 1-5烷基或支链C 4-7 - 烷基的基团,其可任选被羟基,C 1-4 烷氧基,羧基羧酰胺,咪唑基,吲哚基,胍基,-SH或C 1-4 - 烷硫基,此外表示可被卤素,羟基,C 1-4 - 烷基,C 1-4 - 烷氧基,硝基取代的芳基,芳烷基或杂芳基甲基 或-NR 13 R 14基团,其中R 13和R 14彼此独立地表示氢或烷基或与相邻的氮原子一起形成可选地被O,S或N中断的5,6或7-元环,并且其任选地为C1 R 4,R 6,R 8,R 10表示选自该基团的相同或不同的基团 的氢,直链C1-5 - 烷基,代表异丙基,仲丁基,叔丁基,C 2-6 - 烯基,C 3-7 - 环烷基,其可任选被羟基,C 1-4 - 烷氧基, 羧基,羧酰胺,咪唑基,吲哚基,胍基,SH或C 1-4 - 烷硫基,代表可被卤素,羟基,C 1-4 - 烷基,C 1-4 - 烷氧基及其立体异构体取代的芳基,芳烷基或杂芳基甲基, 其制备方法及其作为内寄生物杀虫剂的用途。

    Granular component containing alkylaminotriazole for use in machine dishwashing detergents
    42.
    发明授权
    Granular component containing alkylaminotriazole for use in machine dishwashing detergents 失效
    含有烷基氨基三唑的颗粒组分用于机洗餐具洗涤剂

    公开(公告)号:US06221820B1

    公开(公告)日:2001-04-24

    申请号:US09223143

    申请日:1998-12-30

    IPC分类号: C11D704

    CPC分类号: C11D3/28 C11D3/0073

    摘要: Free-flowing, storage-stable homogeneous granules for protecting silver in machine dishwashing are obtained through a granular free-flowing component comprising an organic solid (I) from the group of alkylaminotriazoles and a constituent (II) selected from the group of alkali metal sulfates, the ratio of solid (I) to solid (II) being from 1:100 to 2:1, preferably from 1:70 to 3:2 and more preferably from 1:50 to 2:3 and the component having a particle size of 0.01 to 2 millimeters, preferably 0.05 to 1.8 millimeters and more preferably 0.1 to 1.6 millimeters.

    摘要翻译: 通过颗粒自由流动组分获得用于保护机器洗碗剂中的银的自由流动的储存稳定的均匀颗粒,其包含来自烷基氨基三唑的有机固体(I)和选自碱金属硫酸盐的组分(II) ,固体(I)与固体(II)的比例为1:100至2:1,优选1:70至3:2,更优选1:50至2:3,并且具有粒径 为0.01〜2毫米,优选为0.05〜1.8毫米,更优选为0.1〜1.6毫米。

    Substituted 1,2,4-oxadiazole derivatives
    44.
    发明授权
    Substituted 1,2,4-oxadiazole derivatives 失效
    取代的1,2,4-恶二唑衍生物

    公开(公告)号:US5371231A

    公开(公告)日:1994-12-06

    申请号:US57584

    申请日:1993-05-05

    CPC分类号: C07D271/06 A01N43/82

    摘要: The present invention relates to new substituted 1,2,4-oxadiazole derivatives of the formula (I) and to their stereoisomers ##STR1## in which formula R.sup.4 represents OH, SH, halogenoalkoxy, halogenoalkylthio, halogenoalkylsulphinyl, halogenoalkylsulphonyl, aryloxy, aralkoxy, arylthio, aralkylthio, alkylenedioxy, halogenoalkylenedioxy, amino, alkylamino, dialkylamino, acylamino, carbamoyl, alkylsulphinyl, alkylsulphonyl, arylsuphinyl, arylsulphonyl, sulphonylamino, alkoxycarbonyl, alkylcarbonyl, alkylcarbonyloxy, alkoxyalkyl, alkoxyalkoxy or hydroxyalkoxy, where in the event that at least one of the radicals R.sup.2 or R.sup.3 is other than hydrogen, R.sup.4 additionally represents halogen, alkyl, halogenoalkyl, alkoxy or thioalkyl, where, in the event that R.sup.1 represents optionally substituted C.sub.1-8 -alkyl, R.sup.4 additionally represents alkoxy,processes for their preparation, and their use as endoparasiticides.

    摘要翻译: 本发明涉及式(I)的新的取代的1,2,4-恶二唑衍生物及其立体异构体,其中式R4代表OH,SH,卤代烷氧基,卤代烷硫基,卤代烷基亚磺酰基,卤代烷基磺酰基,芳氧基, 芳烷氧基,芳硫基,芳烷硫基,亚烷基二氧基,卤代亚烷基二氧基,氨基,烷基氨基,二烷基氨基,酰基氨基,氨基甲酰基,烷基亚磺酰基,烷基磺酰基,芳基亚乙基,芳基磺酰基,磺酰基氨基,烷氧基羰基,烷基羰基,烷基羰基氧基,烷氧基烷基,烷氧基烷氧基或羟基烷氧基,其中在至少一个 基团R2或R3不是氢,R4另外表示卤素,烷基,卤代烷基,烷氧基或硫代烷基,其中,在R 1表示任选取代的C 1-8 - 烷基的情况下,R 4另外表示烷氧基,其制备方法, 并将其用作内寄生物杀灭剂。

    Detergent compacts
    45.
    发明授权
    Detergent compacts 失效
    洗涤剂压块

    公开(公告)号:US4913832A

    公开(公告)日:1990-04-03

    申请号:US302067

    申请日:1989-01-24

    摘要: A detergent compact for dishwashing machines based on alkali metal metasilicates, pentalkali metal tripolyphosphates, active chlorine compound, and surfactant. The compact comprises a cold water-soluble tablet (1) or melt (2) of the metasilicates, tripolyphosphates and surfactant, and a warm water-soluble melt (1) or tablet (2) of the metasilicates, tripolyphosphates and active chlorine compound. The tablet (1) and melt (1) or melt (2) and tablet (2) are combined into a compact having varying solubility at varying water temperatures.

    摘要翻译: 一种基于碱金属偏硅酸盐,五碱金属三聚磷酸盐,活性氯化合物和表面活性剂的洗碗机的洗涤剂。 压块包含偏硅酸盐,三聚磷酸盐和表面活性剂的冷水溶性片剂(1)或熔体(2),以及偏硅酸盐,三聚磷酸盐和活性氯化合物的温水溶性熔融物(1)或片剂(2)。 片剂(1)和熔体(1)或熔体(2)和片剂(2)在变化的水温下组合成具有不同溶解度的压块。

    Multilayer detergent tablets for dishwashing machines
    46.
    发明授权
    Multilayer detergent tablets for dishwashing machines 失效
    餐具洗涤机用多层洗涤剂片

    公开(公告)号:US4828749A

    公开(公告)日:1989-05-09

    申请号:US931503

    申请日:1986-11-17

    摘要: A multilayer detergent tablet for dishwashing machines based on alkali metal metasilicates, pentaalkali metal triphosphates, active chlorine compound, and surfactant. The tablet comprises a first cold water-soluble layer of alkali metal metasilicate nonahydrate, pentaalkali metal triphosphate, and a low-foaming nonionic surfactant; and a second layer which dissolves rapidly at increasing water temperatures comprising alkali metal metasilicate, pentaalkali metal triphosphate, and an active chlorine compound.

    摘要翻译: 一种基于碱金属偏硅酸盐,五碱金属三磷酸盐,活性氯化合物和表面活性剂的洗碗机的多层洗涤剂片剂。 片剂包含第一冷水溶性层碱金属偏硅酸盐九水合物,五碱金属三磷酸盐和低泡非离子表面活性剂; 以及在包括碱金属偏硅酸盐,五碱金属三磷酸盐和活性氯化合物的增加的水温下快速溶解的第二层。

    Refractory article suitable for casting molten metal
    47.
    发明授权
    Refractory article suitable for casting molten metal 失效
    适用于铸造熔融金属的耐火材料

    公开(公告)号:US4634685A

    公开(公告)日:1987-01-06

    申请号:US793687

    申请日:1985-10-31

    CPC分类号: B22D41/54 C04B35/101

    摘要: A refractory article for casting of liquid melts, especially steel, fabricated from a mixture of Al.sub.2 O.sub.3, graphite, a flux component, a synthetic resin binder and a metallic powder. The flux component contains a first flux with a melting point from 550.degree. to 900.degree. C. and a second flux that becomes active in the mixture in a temperature ranging from 1350.degree. and 1550.degree. C. The refractory article need not be heated before use, and the carbon contained therein, which determines the strength of the article, is retained for a much longer period during use, so that the article will have a long service life.

    摘要翻译: 用于铸造由Al 2 O 3,石墨,助熔剂组分,合成树脂粘合剂和金属粉末的混合物制成的液体熔体,特别是钢的耐火制品。 助熔剂组分含有熔点为550-900℃的第一助熔剂和在1350℃至1550℃的温度范围内在混合物中变成活性的第二助熔剂。耐火制品在使用前不需要加热 ,并且确定制品的强度的其中包含的碳在使用期间保持较长时间,使得制品将具有较长的使用寿命。