摘要:
To prevent the solvents forming a gradient from mixing at the wrong place and to provide for accurate composition at start of the gradient in spite of solvent pressure variations, a microliquid or supercritical fluid chromatograph includes a combined mixer and pressure detector in which equal pressures of the two solvents in the gradient are detected by displacement of a ferromagnetic poppet in the mixing chamber. The poppet serves as a stop for the final solvent until the pressures are substantially equal and then its movement is detected by a circuit related to a linear variable differential transformer. The signal energizes a circuit which drives one of the sensing coils to drive the poppet during the gradient to provide mixing.
摘要:
To reduce tailing, the frit at the outlet to the liquid chromatographic column has a diameter substantially equal to that of the inside diameter of the outlet end of the column and less than two millimeters. It is held directly against the packing of the column within a cylindrical member having a shoulder with a central aperture at least the size of the diameter of the frit and cylindrical walls which are fastened to resist force in the direction of the axis of the column from its inlet to its outlet. A gasket seals the cylindrical holder against the column wall. The frit is formed of gold-plated nickel spheres sintered together at temperature lower than the gold-nickel eutectic temperature of 950 degrees Celsius but above the phase-immiscibility temperature of 720 degrees Celsius. The size and shape of the frit is selected to reduce tailing by causing the flow path from the column to be uniform.
摘要:
To prevent the solvents forming a gradient from mixing at the wrong place and to provide for accurate composition at start of the gradient in spite of solvent pressure variations, a microliquid or supercritical fluid chromatograph includes a combined mixer and pressure detector in which equal pressures of the two solvents in the gradient are detected by displacement of a ferromagnetic poppet in the mixing chamber. The poppet serves as a stop for the final solvent until the pressures are substantially equal and then its movement is detected by a circuit related to a linear variable differential transformer. The signal energizes a circuit which drives one of the sensing coils to drive the poppet during the gradient to provide mixing.
摘要:
To detect a ground fault, the alternating current leakage current to common AC electrical ground is sensed across a resistor and applied to one input of an analog gate. The analog gate is opened by the positive going voltage from the high-voltage secondary of the power supply transformers between 7 degrees from the crossover point and 103 degrees to pass only that portion of the potential representing the alternating current leakage current which is in phase with the potential on the secondary windings of the power supply transformer and thus provide a signal representing the real component of the AC impedance to ground. A reference preset level of impedance and the signal from the analog gate are compared to provide a signal whenever the real component of the AC leakage current exceeds the preset value.
摘要:
To provide smooth constant flow from a pump a feedback system comprises: a power means for the pump motor; positive and negative feedback loop means for controlling said power means; means for alternately energizing and de-energizing said positive and negative feedback control means; said negative feedback control means receiving a signal from said means for measuring flow rate and including means for comparing said signal with said corrected flow rate reference signal while said second feedback loop is energized to generate an error signal controlling said power means; and said positive feedback control means applying an acceleration voltage to said motor from a time a preset period after the initiation of a return stroke of said piston until after a timed duration.
摘要:
To provide a reliable start for cadmium and zinc lamps and reduce baseline noise in an absorbance monitor, voltage pulses are applied to the primary of a transformer followed by shutoff of the primary current which discharges the energy stored in the magnetizing inductance of the transformer as three thousand volt peaks in its secondary in a series of timed steps. At the end of the timed period, the system shuts down unless it has approached operating frequency. The frequency is controlled by the amount of current passing through a gas discharge lamp in circuit with the transformer secondary and the frequency controls the amplitude of the voltage spikes. After warm-up, blanking pulses prevent optical noise from electrical-path-change oscillations within the tube. In one embodiment, a constant current source controls the current and in another, an operating current and frequency are established by the transformer leakage inductance and lamp characteristics in the circuit.
摘要:
To reduce errors in a measuring instrument caused by temperature effects from changes in the flow rate of fluids passing through the instrument, the flow of heat is adjusted to balance the flow-rate-dependent temperature increases against the flow-rate-dependent temperature decreases that occur with the same change in flow rate in each flow path. Some of the techniques for adjusting the flow of heat are: (1) controlling the temperature of the fluid at the inlet of the instrument with one heat exchanger and the temperature of the body of the instrument with another heat exchanger; (2) controlling the temperature of the walls of the instrument with a heating coil; and (3) emitting heat within the flow path from a transducer.
摘要:
Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. Similarly, some columns that have a tendency to swell in the presence of aqueous solutions and pressurized while the solution is applied to prevent swelling and wall effect. This procedure also changes the structure in the column. The size of the separation effective openings can be controlled by the amount of the pressure and pores eliminated.
摘要:
A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.
摘要:
To collect analyte from a supercritical fluid extractor, the collector lifts vials into place by a biasing device that guides the file up to the restrictor where it is sealed. The vial can be moved back down from the collecting mechanism even if frost forms on the vial while the restrictor remains stationary. This vial is held in place by a guide that contains the seal for sealing the vial when it is raised in place.