公开(公告)号：US09186128B2

公开(公告)日：2015-11-17

申请号：US12243367

申请日：2008-10-01

申请人： John Mugan ,  Brian Murphy ,  John McWeeney

发明人： John Mugan ,  Brian Murphy ,  John McWeeney

IPC分类号： A61B10/00 ,  A61B10/04 ,  A61B10/02 ,  A61B17/00 ,  A61B17/34 ,  A61B19/00

CPC分类号： A61B10/04 ,  A61B10/0233 ,  A61B10/0283 ,  A61B19/54 ,  A61B2010/045 ,  A61B2017/00424 ,  A61B2017/3413 ,  A61B2090/0801 ,  A61B2090/3925

摘要： A device for needle biopsy is provided. The device includes a handle member having proximal and distal portions. A proximal handle member is disposed to the proximal portion of the handle member and a distal handle member is disposed to the distal portion of the handle member. A sheath lumen is disposed within the handle member and extends from the distal portion of the handle member. A needle housing member is partially disposed to the proximal portion of the handle member and a needle is disposed within the sheath lumen. A plurality of protrusions are disposed upon the needle.

摘要翻译： 提供一种用于针刺活检的装置。 该装置包括具有近端部分和远端部分的手柄部件。 近侧手柄构件设置在手柄构件的近侧部分，并且远端手柄构件设置在手柄构件的远端部分。 护套管腔设置在手柄构件内并从手柄构件的远端部分延伸。 针壳体构件部分地设置在手柄构件的近侧部分上，并且针被设置在鞘腔内。 在针上设置有多个突起。

公开(公告)号：US08709356B2

公开(公告)日：2014-04-29

申请号：US12758395

申请日：2010-04-12

申请人： Brian Murphy ,  Scott Corey ,  Alex Flamm ,  Ben Lane ,  Conrad Laskowski ,  Chad Schneider

发明人： Brian Murphy ,  Scott Corey ,  Alex Flamm ,  Ben Lane ,  Conrad Laskowski ,  Chad Schneider

IPC分类号： B01L3/00

CPC分类号： C12Q1/6806 ,  B01L3/502715 ,  B01L3/502784 ,  B01L7/525 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/147 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2300/18 ,  C12Q2565/629 ,  F04B49/065 ,  F04B49/106 ,  G01N21/66 ,  G01N33/50 ,  G01N2035/00544 ,  H05B1/025 ,  Y10S435/808 ,  Y10S436/805 ,  Y10S436/809 ,  Y10T436/25

摘要： The present invention relates to systems and methods for minimizing or eliminating diffusion effects. Diffused regions of a segmented flow of multiple, miscible fluid species may be vented off to a waste channel, and non-diffused regions of fluid may be preferentially pulled off the channel that contains the segmented flow. Multiple fluid samples that are not contaminated via diffusion may be collected for analysis and measurement in a single channel. The systems and methods for minimizing or eliminating diffusion effects may be used to minimize or eliminate diffusion effects in a microfluidic system for monitoring the amplification of DNA molecules and the dissociation behavior of the DNA molecules.

摘要翻译： 本发明涉及用于最小化或消除扩散效应的系统和方法。 多个可混溶流体物质的分段流的扩散区域可以排出到废物通道，并且流体的非扩散区域可以优先地从包含分段流动的通道中拉出。 可以收集未经扩散污染的多个流体样品，以便在单个通道中进行分析和测量。 可以使用用于最小化或消除扩散效应的系统和方法来最小化或消除用于监测DNA分子的扩增和DNA分子的解离行为的微流体系统中的扩散效应。

公开(公告)号：US08589321B2

公开(公告)日：2013-11-19

申请号：US13099268

申请日：2011-05-02

申请人： Michael J. Baum ,  David Carasso ,  Robin K. Das ,  Brad Hall ,  Brian Murphy ,  Stephen Sorkin ,  Andre Stechert ,  Erik M. Swan ,  Rory Greene ,  Nicholas Christian Mealy ,  Christina Noren

发明人： Michael J. Baum ,  David Carasso ,  Robin K. Das ,  Brad Hall ,  Brian Murphy ,  Stephen Sorkin ,  Andre Stechert ,  Erik M. Swan ,  Rory Greene ,  Nicholas Christian Mealy ,  Christina Noren

IPC分类号： G06F15/18

CPC分类号： G06F17/30604 ,  G06F11/3476 ,  G06F17/2785 ,  G06F17/30368 ,  G06F17/30477 ,  G06F17/30507 ,  G06F17/30525 ,  G06F17/30551 ,  G06F17/30598 ,  G06F17/30619 ,  G06F17/30657 ,  G06F17/30705 ,  G06K9/6217 ,  H04L63/1425 ,  H04L63/20

摘要： Methods and apparatus consistent with the invention provide the ability to organize and build understandings of machine data generated by a variety of information-processing environments. Machine data is a product of information-processing systems (e.g., activity logs, configuration files, messages, database records) and represents the evidence of particular events that have taken place and been recorded in raw data format. In one embodiment, machine data is turned into a machine data web by organizing machine data into events and then linking events together.

公开(公告)号：USD686334S1

公开(公告)日：2013-07-16

申请号：US29385967

申请日：2011-02-23

申请人： Eric Schneider ,  Alex Flamm ,  Brian Murphy ,  Chad Schneider ,  Charly Mar ,  Ben Lane ,  Jeremy Savage ,  Conrad Laskowski

设计人： Eric Schneider ,  Alex Flamm ,  Brian Murphy ,  Chad Schneider ,  Charly Mar ,  Ben Lane ,  Jeremy Savage ,  Conrad Laskowski

公开(公告)号：US08395164B2

公开(公告)日：2013-03-12

申请号：US13225826

申请日：2011-09-06

申请人： Brian Murphy ,  Reinhold Wahlich

发明人： Brian Murphy ,  Reinhold Wahlich

IPC分类号： H01L29/15

CPC分类号： H01L21/76254

摘要： Silicon carbide substrate wafers are prepared by transferring a monocrystalline silicon layer from a donor wafer onto a handle wafer, the silicon layer being implanted with carbon and annealed to form a monocrystalline SiC layer prior to or after transfer of the silicon layer.

摘要翻译： 通过将单晶硅层从施主晶片转移到处理晶片上来制备碳化硅衬底晶片，硅层被注入碳并在硅层转移之前或之后退火以形成单晶SiC层。

公开(公告)号：US20120156585A1

公开(公告)日：2012-06-21

申请号：US13373484

申请日：2011-11-14

申请人： Faris Modawar ,  Jeff Miller ,  Mike Jura ,  Brian Murphy ,  Marcie Black ,  Brent A. Buchine

发明人： Faris Modawar ,  Jeff Miller ,  Mike Jura ,  Brian Murphy ,  Marcie Black ,  Brent A. Buchine

IPC分类号： H01M4/92 ,  H01M4/86 ,  H01M4/38 ,  H01L31/0264 ,  H01L31/18 ,  C03C25/68 ,  H01M8/10 ,  B82Y30/00

CPC分类号： H01L21/3086 ,  B82Y10/00 ,  H01L21/30604

摘要： A process is provided for etching a silicon-containing substrate. In the process, the surface of the substrate is cleaned. A film of alumina is deposited on the cleaned substrate surface. A silver film is deposited above the film of alumina. An etchant comprising HF is contacted with the silver film.

摘要翻译： 提供了用于蚀刻含硅衬底的工艺。 在该过程中，清洁基板的表面。 氧化铝膜沉积在清洁的基底表面上。 银膜沉积在氧化铝膜的上方。 包含HF的蚀刻剂与银膜接触。

公开(公告)号：US08179717B2

公开(公告)日：2012-05-15

申请号：US12569869

申请日：2009-09-29

申请人： Zac Shepard ,  Xiaoyu Yang ,  Albert Meeks ,  Qing Li ,  Enosh Levi ,  Kim Le ,  Raz Dan ,  Brian Murphy

发明人： Zac Shepard ,  Xiaoyu Yang ,  Albert Meeks ,  Qing Li ,  Enosh Levi ,  Kim Le ,  Raz Dan ,  Brian Murphy

IPC分类号： G11C11/34 ,  G11C16/04

CPC分类号： G11C11/5621 ,  H01L21/563 ,  H01L24/16 ,  H01L24/29 ,  H01L24/32 ,  H01L24/45 ,  H01L2224/32225 ,  H01L2224/45124 ,  H01L2224/45144 ,  H01L2224/48227 ,  H01L2224/73204 ,  H01L2225/06562 ,  H01L2924/01013 ,  H01L2924/01077 ,  H01L2924/01079 ,  H01L2924/014 ,  H01L2924/07802 ,  H01L2924/14 ,  H01L2924/15311 ,  H01L2924/181 ,  H01L2924/00014 ,  H01L2924/00 ,  H01L2924/00012

摘要： A non-volatile memory chip package is prepared for surface mounting to a substrate in a solder reflow process by programming erased blocks to higher threshold voltage levels, to improve data retention for blocks which are preloaded with content, such as by an electronic device manufacturer. Following the surface mounting, the previously-erased blocks are returned to the erased state. The threshold voltage of storage elements of the preloaded blocks can change during the surface mounting process due to a global charge effect phenomenon. The effect is most prominent for higher state storage elements which are surrounded by erased blocks, in a chip for which the wafer backside was thinned and polished. The erased blocks can be programmed using a single program pulse without performing a verify operation, as a wide threshold voltage distribution is acceptable.

摘要翻译： 通过将擦除的块编程为更高的阈值电压电平来准备用于在焊料回流过程中表面安装到衬底的非易失性存储器芯片封装，以改善例如由电子器件制造商预装载内容的块的数据保留。 在表面安装之后，先前擦除的块返回到擦除状态。 由于全局充电效应现象，预载块的存储元件的阈值电压可能在表面贴装过程中发生变化。 对于被擦除块包围的较高状态存储元件，晶片背面被薄化和抛光的芯片中的效果最为突出。 擦除的块可以使用单个编程脉冲编程，而不执行验证操作，因为宽的阈值电压分布是可接受的。

公开(公告)号：US20120117079A1

公开(公告)日：2012-05-10

申请号：US13353135

申请日：2012-01-18

申请人： Michael J. Baum ,  David Carasso ,  Robin K. Das ,  Rory Greene ,  Brad Hall ,  Nick Mealy ,  Brian Murphy ,  Stephen Sorkin ,  Andre Stechert ,  Eric M. Swan

发明人： Michael J. Baum ,  David Carasso ,  Robin K. Das ,  Rory Greene ,  Brad Hall ,  Nick Mealy ,  Brian Murphy ,  Stephen Sorkin ,  Andre Stechert ,  Eric M. Swan

IPC分类号： G06F17/30

CPC分类号： G06F17/30336 ,  G06F17/30321 ,  G06F17/30342 ,  G06F17/30353 ,  G06F17/30516 ,  G06F17/30528 ,  G06F17/3053 ,  G06F17/30551 ,  G06F17/30554 ,  G06F17/30864

摘要： Methods and apparatus consistent with the invention provide the ability to organize, index, search, and present time series data based on searches. Time series data are sequences of time stamped records occurring in one or more usually continuous streams, representing some type of activity. In one embodiment, time series data is organized into discrete events with normalized time stamps and the events are indexed by time and keyword. A search is received and relevant event information is retrieved based in whole or in part on the time indexing mechanism, keyword indexing mechanism, or statistical indices calculated at the time of the search.

摘要翻译： 根据本发明的方法和设备提供了基于搜索来组织，索引，搜索和呈现时间序列数据的能力。 时间序列数据是在一个或多个通常连续的流中发生的时间戳记录的序列，表示某种类型的活动。 在一个实施例中，时间序列数据被组织成具有归一化时间戳的离散事件，并且事件由时间和关键字索引。 完全或部分地基于搜索时计算的时间索引机制，关键字索引机制或统计索引，检索相关的事件信息。

公开(公告)号：US08112425B2

公开(公告)日：2012-02-07

申请号：US11868370

申请日：2007-10-05

申请人： Michael J. Baum ,  David Carasso ,  Robin K. Das ,  Rory Greene ,  Brad Hall ,  Nick Mealy ,  Brian Murphy ,  Stephen Sorkin ,  Andre Stechert ,  Erik M. Swan

发明人： Michael J. Baum ,  David Carasso ,  Robin K. Das ,  Rory Greene ,  Brad Hall ,  Nick Mealy ,  Brian Murphy ,  Stephen Sorkin ,  Andre Stechert ,  Erik M. Swan

IPC分类号： G06F17/30

CPC分类号： G06F17/30336 ,  G06F17/30321 ,  G06F17/30342 ,  G06F17/30353 ,  G06F17/30516 ,  G06F17/30528 ,  G06F17/3053 ,  G06F17/30551 ,  G06F17/30554 ,  G06F17/30864

摘要： Methods and apparatus consistent with the invention provide the ability to organize, index, search, and present time series data based on searches. Time series data are sequences of time stamped records occurring in one or more usually continuous streams, representing some type of activity. In one embodiment, time series data is organized into discrete events with normalized time stamps and the events are indexed by time and keyword. A search is received and relevant event information is retrieved based in whole or in part on the time indexing mechanism, keyword indexing mechanism, or statistical indices calculated at the time of the search.

摘要翻译： 根据本发明的方法和设备提供了基于搜索来组织，索引，搜索和呈现时间序列数据的能力。 时间序列数据是在一个或多个通常连续的流中发生的时间戳记录的序列，表示某种类型的活动。 在一个实施例中，时间序列数据被组织成具有归一化时间戳的离散事件，并且事件由时间和关键字索引。 完全或部分地基于搜索时计算的时间索引机制，关键字索引机制或统计索引，检索相关的事件信息。

公开(公告)号：US07838296B2

公开(公告)日：2010-11-23

申请号：US10229030

申请日：2002-08-28

申请人： Scott Corey ,  John Sakers ,  Keith Lipford ,  Samuel Reed ,  Brian Murphy

发明人： Scott Corey ,  John Sakers ,  Keith Lipford ,  Samuel Reed ,  Brian Murphy

IPC分类号： G01N31/00

CPC分类号： G01N29/024 ,  G01H5/00 ,  G01N29/032 ,  G01N33/491 ,  G01N2291/02466 ,  G01N2291/02881 ,  Y10T436/101666

摘要： The present invention provides an apparatus and method for measuring the properties of blood using ultrasound. The present invention is particularly suitable for measuring HCT, HGB, MCV, RBC, MCHC, MCH or TPC of blood.

摘要翻译： 本发明提供一种使用超声波测量血液性质的装置和方法。 本发明特别适用于测量血液的HCT，HGB，MCV，RBC，MCHC，MCH或TPC。