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143 条记录 (耗时 0.027 秒)

    Cationic hydrophilic siloxanyl monomers
    43.
    发明授权
    Cationic hydrophilic siloxanyl monomers 有权
    阳离子亲水硅氧烷基单体

    公开(公告)号：US07622512B2

    公开(公告)日：2009-11-24

    申请号：US11341208

    申请日：2006-01-27

    申请人： Derek Schorzman ,  Joseph C. Salamone ,  Daniel Ammon ,  Jay Kunzler ,  Jeffrey G. Linhardt

    发明人： Derek Schorzman ,  Joseph C. Salamone ,  Daniel Ammon ,  Jay Kunzler ,  Jeffrey G. Linhardt

    IPC分类号： G02B1/04 ,  C08F290/06

    CPC分类号： C08F230/08 ,  C08F226/10

    摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers.

    摘要翻译： 本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。 更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子单体。 这些性质包括用水提取聚合的医疗装置的能力。 这避免了使用本领域典型的有机溶剂。 聚合物组合物包含聚合的阳离子亲水硅氧烷基单体。

    Polymerization products and biomedical devices containing same
    47.
    发明授权
    Polymerization products and biomedical devices containing same 失效
    聚合产物和含有其的生物医学装置

    公开(公告)号：US07425600B2

    公开(公告)日：2008-09-16

    申请号：US11174020

    申请日：2005-07-01

    申请人： Derek Schorzman ,  Joseph C. Salamone

    发明人： Derek Schorzman ,  Joseph C. Salamone

    IPC分类号： C08F114/18

    CPC分类号： C08G77/385 ,  C08F214/18 ,  C08F290/062 ,  C08F290/068 ,  G02B1/043 ,  C08L27/12

    摘要： Polymerization products formed from a monomeric mixture comprising (a) one or more first monomers of the general formula I: A-L-R1—(X—CF═CF2)n  (I) wherein R1 represents one or more inertly substituted groups; X is independently a group which links the inertly substituted groups and the trifluorovinyl group; L is an optional linking group; A is CO2Z, SO2Z, PO3Z, or OPO3Z wherein Z is hydrogen or an alkali metal and n is an integer of 1 to about 1000; (b) one or more second crosslinking monomers comprising at least three trifluorovinyl groups and (c) one or more prepolymers comprising one or more trifluorovinyl groups are provided. Also provided are biomedical devices formed from such polymerization products.

    摘要翻译： 由单体混合物形成的聚合产物包含（a）一种或多种通式I的第一单体：<？in-line-formula description =“In-line formula”end =“lead”→> ALR < /（X-CF-CF 2）N（I）<？in-line-formula description =“In-line Formulas”end =“tail” 其中R 1表示一个或多个惰性取代基团; X独立地是连接惰性取代基和三氟乙烯基的基团; L是可选的连接基团; A是CO 2 Z，SO 2 Z，PO 3 Z或OPO 3 Z其中Z是氢 或碱金属，n为1〜1000的整数， （b）提供包含至少三个三氟乙烯基的一种或多种第二交联单体和（c）一种或多种包含一个或多个三氟乙烯基的预聚物。 还提供了由这种聚合产物形成的生物医学装置。

    Surface treatment of medical device
    50.
    发明授权
    Surface treatment of medical device 有权
    医疗器械表面处理

    公开(公告)号：US06958169B2

    公开(公告)日：2005-10-25

    申请号：US10321949

    申请日：2002-12-17

    申请人： Jay F. Künzler ,  Joseph A. McGee ,  Joseph C. Salamone ,  David E. Seelye

    发明人： Jay F. Künzler ,  Joseph A. McGee ,  Joseph C. Salamone ,  David E. Seelye

    IPC分类号： A61L27/34 ,  A61L27/50 ,  A61L31/10 ,  A61L27/08 ,  G02C7/04

    CPC分类号： A61L27/34 ,  A61L27/50

    摘要： A method for improving the wettability of a medical device involves: (a) providing a medical device formed from a monomer mixture comprising a hydrophilic device-forming monomer including a copolymerizable group and an electron donating moiety, and a second device-forming monomer including a copolymerizable group and a reactive functional group; and (b) contacting a surface of the medical device with a wetting agent including a proton donating moiety reactive with the functional group provided by the second lens-forming monomer and that complexes with the electron donating moiety provided by the hydrophilic lens-forming monomer.

    摘要翻译： 一种用于改善医疗装置的润湿性的方法包括：（a）提供由包含包含可共聚基团和给电子部分的亲水装置形成单体的单体混合物形成的医疗装置，以及第二装置形成单体， 可共聚基团和反应性官能团; 和（b）使医疗装置的表面与包含与由第二透镜形成性单体提供的官能团反应的质子供体部分的润湿剂和与亲水性透镜形成性单体提供的给电子部分的配合物接触。