公开(公告)号：US20030199955A1

公开(公告)日：2003-10-23

申请号：US10126539

申请日：2002-04-22

发明人： Chester Struble ,  Pierre A. Grandjean ,  Volkert A. Zeijlemaker ,  Karel F.A.A. Smits

IPC分类号： A61N001/05 ,  A61N001/00

CPC分类号： A61N1/0597

摘要： The invention is directed to techniques for electrode placement around a heart. A harness having one or more attachment sites may be secured around the heart, and electrodes may be secured at the attachment sites as desired by the physician for the patient. The electrodes may be, for example, pacing and sensing electrodes, defibrillation electrodes, or any combination thereof. The harness holds the electrodes in place and also impedes the progress of ventricular dilation. The electrodes attached to the harness may be used for any of several purposes, such as cardiac resynchronization, selective defibrillation, measurement of impedance, pacing and cardioversion.

摘要翻译： 本发明涉及用于围绕心脏放置电极的技术。 具有一个或多个附着部位的线束可以被固定在心脏周围，并且电极可以根据医师对患者的需要固定在附着位置。 电极可以是例如起搏和感测电极，除颤电极或其任何组合。 线束将电极固定在适当的位置，并且也阻碍了心室扩张的进展。 连接到线束的电极可用于几种目的中的任何一种，例如心脏再同步，选择性除颤，阻抗测量，起搏和心脏复律。

公开(公告)号：US12121738B2

公开(公告)日：2024-10-22

申请号：US17900726

申请日：2022-08-31

申请人： ATACOR MEDICAL, INC.

发明人： Rick Sanghera ,  Brent Cadavona ,  Matthew Rollins ,  Tim Searfoss ,  Brian Walguarnery ,  Michel Gelineau

IPC分类号： A61N1/39 ,  A61N1/05

CPC分类号： A61N1/39622 ,  A61N1/059 ,  A61N1/0597

摘要： Disclosed is a delivery system for a component, for example, a splitting lead. A splitting lead can have a proximal portion to engage a controller and a distal portion to split apart into sub-portions that travel in multiple directions during implantation into a patient. The delivery system can include a handle and a component advancer to advance and removably engage a portion of the component. The component advancer can be coupled to the handle and advance the component into the patient by applying a force to the portion in response to actuation of the handle by the operator. Also, the delivery system can include an insertion tip with first and second ramps to facilitate advancement of first and second sub-portions into the patient in first and second directions. The leads may have various electrode configurations including, for example, wrapped or embedded electrodes, helical or elliptical coils, thin metallic plates, etc.

公开(公告)号：US11672975B2

公开(公告)日：2023-06-13

申请号：US16888462

申请日：2020-05-29

申请人： ATACOR MEDICAL, INC.

发明人： Rick Sanghera ,  Matthew Rollins ,  John Beck ,  William Born ,  Shahn Sage ,  Alan Marcovecchio

IPC分类号： A61B17/34 ,  A61N1/05 ,  A61N1/37 ,  A61B17/00

CPC分类号： A61N1/0597 ,  A61B17/3468 ,  A61N1/05 ,  A61N1/37 ,  A61B2017/00367 ,  A61B2017/00867

摘要： Systems, methods, and devices to facilitate insertion of certain leads with electrode(s) into patients are described. Leads can be implanted to work in conjunction with a cardiac pacemaker or cardiac defibrillator. A lead for cardiac therapy may be inserted into an intercostal space associated with the cardiac notch of a patient. Devices for delivery may include, for example, a delivery system coupled with an electrical lead and having a handle, a component advancer and insertion tips. The handle is configured to be actuated by an operator and the component advancer is configured to advance an electrical lead into the patient. The insertion tips can be configured to close around the electrical lead within the component advancer, to push through biological tissue, and to open to enable the lead to advance into the patient. The electrical lead can also be maintained in a particular orientation during the advancement into the patient.

公开(公告)号：US20230149707A1

公开(公告)日：2023-05-18

申请号：US17995100

申请日：2021-03-29

申请人： Berlin Heals GmbH

发明人： Johannes Müller

IPC分类号： A61N1/20 ,  A61N1/05

CPC分类号： A61N1/205 ,  A61N1/0587 ,  A61N1/0507 ,  A61N1/0514 ,  A61N1/0597

摘要： A process of treatment of internal organ oedema is using an electric current delivering electrode system comprising electrodes to be positioned at two places on the outer surface of the internal organ and/or in a liquid carrying vessel of the internal organ and delivering electric current to induce electro-osmosis between the electrodes. An electrode assembly system for this treatment by electro-osmosis includes, in addition to the two electrodes, a control unit adapted to control the current flow between the two electrodes.

公开(公告)号：US20170105675A1

公开(公告)日：2017-04-20

申请号：US15394852

申请日：2016-12-30

申请人： Xiaohui Zhou

发明人： Xiaohui Zhou ,  Lei Han ,  Yuyan Zhou ,  Li Zhou ,  Guohua Li ,  Yongzhen Li

IPC分类号： A61B5/00 ,  A61B5/0402 ,  A61B5/0205 ,  A61B5/01 ,  A61N1/362 ,  A61B5/02 ,  A61N2/00 ,  A61H9/00 ,  A61M5/31 ,  A61M39/10 ,  A61N2/02 ,  A61B5/145

CPC分类号： A61B5/4836 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/026 ,  A61B5/0432 ,  A61B5/14503 ,  A61B5/14539 ,  A61H9/00 ,  A61M1/106 ,  A61M1/1068 ,  A61M1/122 ,  A61M5/31 ,  A61M39/10 ,  A61N1/0597 ,  A61N1/362 ,  A61N2/002

摘要： A surface attached cardiac function monitor and/or intervention system comprises of a cardiac support device, a cardiac function monitor device and/or intervention device. Cardiac support device is attached on an external or internal surface of a cardiac chamber and supports it. The cardiac function monitor device is connected with a biochemical and physiological sensor. The physiological and biochemical sensor transmits variations of biochemical and physiological parameters that are received by the cardiac function monitor device. The intervention device has at least one member selected from pressure intervention device, an electrical/magnetic stimulation intervention device and a medicine intervention device. This medical system of the present invention could help in diagnosis as well as treatment of the heart failure and other myocardial diseases to improve the condition of patient. It could also be helpful for the monitoring, diagnosis and treatment of diseases of lungs, kidney, liver, spleen, stomach and bladder, etc.

公开(公告)号：US09572977B2

公开(公告)日：2017-02-21

申请号：US14605804

申请日：2015-01-26

申请人： SORIN CRM SAS

发明人： Jean-François Ollivier

IPC分类号： A61N1/00 ,  A61N1/05

CPC分类号： A61N1/059 ,  A61N1/0587 ,  A61N1/0592 ,  A61N1/0597

摘要： An epicardial stimulation lead includes a lead body having a connector at a proximal end for coupling the lead to a generator of an active implantable medical device. The lead also includes a distributor housing at a distal end of the lead body and means for anchoring the distal end of the lead body to the epicardium. The lead also includes an active part having a plurality of microcable conductors, the proximal ends being coupled to the distributor housing, the distal ends being free. Each microcable has a diameter of at most equal to 2 French. Each microcable includes at least one denuded area in the insulating coating forming a stimulation electrode adapted to contact or penetrate an epicardium wall. Each microcable also includes a transverse elongated member extending at an angle relative to the main direction of the microcable for penetrating into the epicardial wall.

摘要翻译： 心外膜刺激引线包括具有在近端处的连接器的引线体，用于将引线耦合到主动植入式医疗装置的发生器。 引线还包括在引线主体的远端处的分配器壳体和用于将引线主体的远端固定到心外膜的装置。 引线还包括具有多个微电极导体的有源部分，该近端耦合到分配器壳体，远端是自由的。 每个microcable的直径最多等于2 French。 每个微电极包括绝缘涂层中的至少一个裸露区域，形成适于接触或穿透心外膜壁的刺激电极。 每个微电缆还包括横向细长构件，该横向细长构件相对于微孔的主要方向以一定角度延伸，用于穿透到心外壁。

公开(公告)号：US09220899B2

公开(公告)日：2015-12-29

申请号：US13818663

申请日：2011-08-26

申请人： Giorgio Cattaneo ,  Alfred Stett ,  Alireza Gharabaghi

发明人： Giorgio Cattaneo ,  Alfred Stett ,  Alireza Gharabaghi

IPC分类号： A61N1/05 ,  A61N1/36

CPC分类号： A61N1/36114 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/0597

摘要： An electrode for medical applications for neuromodulation and/or nerve stimulation and/or neurological signal detection, which electrode can be compressed and expanded in order to insert same into a hollow organ of a body and is or can be coupled to a current supply. The electrode has a compressible and expandable lattice structure including lattice webs, which form cells, wherein the lattice structure is or can be coupled to the current supply and forms at least one electrically conductive region and at least one electrically insulated region.

摘要翻译： 用于神经调节和/或神经刺激和/或神经信号检测的医疗应用的电极，该电极可以被压缩和扩张，以将其插入身体的中空器官并且可以耦合到电流源。 电极具有可压缩和可扩展的格子结构，其包括晶格网，其形成电池，其中晶格结构可耦合到电流源并形成至少一个导电区域和至少一个电绝缘区域。

公开(公告)号：US09114009B2

公开(公告)日：2015-08-25

申请号：US13997939

申请日：2011-12-28

申请人： Tal Dvir ,  Daniel S. Kohane ,  Robert S. Langer ,  Brian Timko

发明人： Tal Dvir ,  Daniel S. Kohane ,  Robert S. Langer ,  Brian Timko

IPC分类号： A61F2/24 ,  A61L27/44 ,  A61N1/05 ,  B82Y5/00

CPC分类号： A61F2/2418 ,  A61L27/3826 ,  A61L27/44 ,  A61L27/446 ,  A61L27/54 ,  A61L2400/12 ,  A61N1/0597 ,  B82Y5/00 ,  Y10S977/762

摘要： Electrically conductive nanowires incorporated within scaffolds enhance tissue growth, bridge the electrically resistant pore walls and markedly improve electrical communication between adjacent cardiac cell bundles. Integration of conducting nanowires within 3D scaffolds should improve the therapeutic value of cardiac patches. Examples demonstrate efficacy of gold nanowires in alginate matrices seeded with cardiomyocytes.

摘要翻译： 掺入支架内的导电纳米线增强组织生长，桥接电阻孔壁并显着改善相邻心肌细胞束之间的电连通。 导管纳米线在3D支架内的整合应提高心脏贴片的治疗价值。 实施例证明金纳米线在与心肌细胞接种的藻酸盐基质中的功效。

公开(公告)号：US20150134042A1

公开(公告)日：2015-05-14

申请号：US14605804

申请日：2015-01-26

申请人： SORIN CRM SAS

发明人： Jean-François Ollivier

IPC分类号： A61N1/05

CPC分类号： A61N1/059 ,  A61N1/0587 ,  A61N1/0592 ,  A61N1/0597

摘要： An epicardial stimulation lead includes a lead body having a connector at a proximal end for coupling the lead to a generator of an active implantable medical device. The lead also includes a distributor housing at a distal end of the lead body and means for anchoring the distal end of the lead body to the epicardium. The lead also includes an active part having a plurality of microcable conductors, the proximal ends being coupled to the distributor housing, the distal ends being free. Each microcable has a diameter of at most equal to 2 French. Each microcable includes at least one denuded area in the insulating coating forming a stimulation electrode adapted to contact or penetrate an epicardium wall. Each microcable also includes a transverse elongated member extending at an angle relative to the main direction of the microcable for penetrating into the epicardial wall.

摘要翻译： 心外膜刺激引线包括具有在近端处的连接器的引线体，用于将引线耦合到主动植入式医疗装置的发生器。 引线还包括在引线主体的远端处的分配器壳体和用于将引线主体的远端固定到心外膜的装置。 引线还包括具有多个微电极导体的有源部分，该近端耦合到分配器壳体，远端是自由的。 每个microcable的直径最多等于2 French。 每个微电极包括绝缘涂层中的至少一个裸露区域，形成适于接触或穿透心外膜壁的刺激电极。 每个微电缆还包括横向细长构件，该横向细长构件相对于微孔的主要方向以一定角度延伸，用于穿透到心外壁。

公开(公告)号：US20150066125A1

公开(公告)日：2015-03-05

申请号：US14465253

申请日：2014-08-21

申请人： Peter Osypka

发明人： Peter Osypka

IPC分类号： A61N1/05

CPC分类号： A61N1/059 ,  A61N1/0492 ,  A61N1/0597 ,  A61N1/3684 ,  A61N1/3968

摘要： The invention relates to an electrode assembly for temporary cardioversion/defibrillation and/or for temporary stimulation of the heart after open heart surgery consisting of two defibrillation electrodes with at least one indifferent pole each and an elastic section, where each defibrillation electrode in the operating position is positioned on the right and left atrium, which means the defibrillation electrodes together include the right and left atrium. The defibrillation electrodes each distally comprise a fixation member and each proximally end into a protective tube to protect the epicardium. The fixation members are elastic and enable reversible fastening of the defibrillation electrodes in the pericardium on the right and left side. The protective tubes are preferably fed together into a guide tube, where the guide tube is slidable along the longitudinal axis. The stimulation electrodes (different electrode poles) for stimulation of the atria are designed appropriately together with the defibrillation electrode in one piece.

摘要翻译： 本发明涉及一种用于临时心脏复律/除颤的电极组件和/或用于在开放心脏手术之后暂时刺激心脏的电极组件，其由具有至少一个无差异极点的两个除颤电极和弹性部分组成，其中每个除颤电极处于操作位置 位于右心房和左心房，这意味着除颤电极一起包括右心房和左心房。 除颤电极各自远端地包括固定构件，并且每个近端终止于保护管中以保护心外膜。 固定构件是弹性的，并且能够使右心和左侧的除颤电极可逆地紧固在心包中。 保护管优选地一起馈送到引导管中，其中引导管可沿着纵向轴线滑动。 用于刺激心房的刺激电极（不同电极极）与除颤电极一起适当地设计。