公开(公告)号：US10514361B2

公开(公告)日：2019-12-24

申请号：US16107792

申请日：2018-08-21

Applicant: National Technology & Engineering Solutions of Sandia, LLC ,  STC.UNM

Inventor： Timothy J. Boyle ,  Khalid Mikhiel Hattar ,  Fernando Henry Garzon ,  Stephen J. Bauer

IPC: G01N27/62 ,  H01J37/08 ,  G01K3/00 ,  B82Y40/00 ,  C04B41/00 ,  B82Y15/00

Abstract: Ion-doped metal or ceramic nanoparticles can be added into, for example, a component that upon exposure to an environmental stimulus, will release the ion and ‘tattle’ on any impending destruction.

公开(公告)号：US10436570B1

公开(公告)日：2019-10-08

申请号：US15330822

申请日：2016-11-07

Applicant: Arash Kheyraddini-Mousavi ,  Zayd Leseman ,  Behnam Kheyraddini-Mousavi

Inventor： Arash Kheyraddini-Mousavi ,  Zayd Leseman ,  Behnam Kheyraddini-Mousavi

IPC: G01B9/02 ,  G02B21/08 ,  G02B21/00 ,  G02B27/09

Abstract: The present invention provides a Michelson interferometer for capturing images of a vibrating sample comprising a coherent light source. The light source may be adapted to illuminate a sample with a constant brightness across the sample. The interferometer may also be configured to generate a 3D representation of a sample using a single frame for a predetermined phase of the sample. The 3D representations may be combined to create a 3D video representation of the vibrating sample.

公开(公告)号：US10389745B2

公开(公告)日：2019-08-20

申请号：US15750236

申请日：2016-08-04

Applicant: STC.UNM

Inventor： Abdullah Mueen ,  Nikan Chavoshi

IPC: G06F11/00 ,  G06F12/14 ,  G06F12/16 ,  G08B23/00 ,  H04L29/06 ,  G06F16/22 ,  G06Q50/00 ,  G06F21/57

Abstract: Bots are detected real-time by correlating activity between users using a lag-sensitive hashing technique that captures warping-invariant correlation. Correlated users groups in social media may be found that represent bot behavior with thousands of bot accounts detected in a couple of hours.

公开(公告)号：US20190138685A1

公开(公告)日：2019-05-09

申请号：US16096494

申请日：2017-05-01

Applicant: STC.UNM

Inventor： Joseph Costantine ,  Sergio A Pellegrino ,  Maria Sakovsky

IPC: G06F17/50 ,  H01Q1/36 ,  H01Q11/08 ,  H01Q1/28 ,  H01Q13/02

Abstract: A system and method for designing an antenna wherein a plurality of antenna designs are visually compared using performance metric plots that distinguish between geometries that meet all requirements and designs that do not.

公开(公告)号：US10279019B2

公开(公告)日：2019-05-07

申请号：US15118143

申请日：2015-02-11

Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES ,  STC.UNM

Inventor： Alan Remaley ,  John T. Schiller ,  Marcelo Amar ,  Bryce Chackerian

IPC: C07K11/00 ,  A61K38/10 ,  A61K39/00 ,  A61P9/10 ,  C12N9/64 ,  A61K45/06 ,  A61K47/69 ,  C07K14/47

Abstract: A vaccine construct comprising an antigenic PCSK9 peptide and an immunogenic carrier, and methods of using the same that are effective to lower blood cholesterol levels in a mammal and treat dyslipidemias and related disease states in a mammal without the frequency of administration required by passive immunity strategies.

公开(公告)号：US10251870B2

公开(公告)日：2019-04-09

申请号：US15556055

申请日：2016-03-02

Applicant: STC.UNM

Inventor： Eric R. Prossnitz ,  Matthias Barton ,  Matthias R. Meyer

IPC: A61K31/436 ,  A61K31/435 ,  A61K31/4355 ,  A61K31/437 ,  A61K31/16 ,  A61K31/7088 ,  A61K38/28

Abstract: The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS).

公开(公告)号：US10249780B1

公开(公告)日：2019-04-02

申请号：US15424464

申请日：2017-02-03

Applicant: STC.UNM

Inventor： Ganesh Balakrishnan ,  Adam Alexander Hecht ,  Erin Ivey Vaughan

IPC: H01L21/00 ,  H01L31/08 ,  H01L31/18 ,  H01L31/0304 ,  H01L31/0216 ,  H01L31/0392

Abstract: Provided is a method of making a radiation detector, including: growing a thin film on a substrate. The substrate is a silicon substrate. The thin film includes aluminum antimony alloy (AlSb). The growing is epitaxial growth via ultra-high vacuum molecular beam epitaxy (UHV-MBE).

公开(公告)号：US10230369B2

公开(公告)日：2019-03-12

申请号：US14913454

申请日：2014-08-28

Applicant: STC.UNM

Inventor： James Plusquellic ,  James Aarestad

IPC: H05B33/08 ,  H03K19/003 ,  H03K19/21 ,  H03K3/84 ,  H03K23/00

Abstract: A Hardware-Embedded Delay PUF (HELP) leverages entropy by monitoring path stability and measuring path delays from core logic macros. HELP incorporates techniques to deal with bias. A unique feature of HELP is that it may compare data measured from different test structures. HELP may be implemented in existing FPGA platforms. HELP may leverage both path stability and within-die variations as sources of entropy.

公开(公告)号：US10220008B2

公开(公告)日：2019-03-05

申请号：US14911943

申请日：2014-08-14

Applicant: STC.UNM

Inventor： Jeff Wade Hill

IPC: A61K31/138 ,  A61K9/00 ,  A61K31/27 ,  A61K31/325 ,  A61K45/06 ,  G01N33/50

Abstract: Using high-throughput screening, in an oxygen-glucose deprivation (OGD) model, isoxsuprine hydrochloride was identified as a potent neuroprotective compound. In an animal middle artery occlusion (MCAO) model of transient focal ischemia, isoxsuprine significantly reduced infarct volume compared to vehicle. The invention, therefore, provides methods of treatment and pharmaceutical compositions that are useful in the treatment and prevention of a wide-variety of ischemia-related injuries, including stroke.

公开(公告)号：US10192709B2

公开(公告)日：2019-01-29

申请号：US15829278

申请日：2017-12-01

Applicant: STC.UNM

Inventor： Edl Schamiloglu ,  Mikhail I. Fuks

IPC: H01J25/50 ,  H01J23/20 ,  H01J23/02

Abstract: The present invention provides a relativistic magnetron including an anode with an entrant channel, the channel having an input end, an output end and a dimensional discontinuity between the ends. The channel is connected to the magnetron and has an anode defining an interaction space located between the dimensional discontinuity and output end. Also provided is a cathode, located upstream, a spaced distance away from the interaction space towards the input end, the cathode is adapted to send an electron beam into the interaction space where the electron beam forms a virtual cathode in the interaction space.