DIAGNOSTIC TEST
    55.
    发明申请
    DIAGNOSTIC TEST 审中-公开
    诊断测试

    公开(公告)号:US20140378347A1

    公开(公告)日:2014-12-25

    申请号:US14478221

    申请日:2014-09-05

    Abstract: Disclosed are methods for conducting diagnostic tests for the detection of the inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. Also described are methods for monitoring a patient by administering tests of the present invention. Also described are methods for monitoring patient's treatment by administering tests of the present invention. Also described are methods for evaluating the effectiveness of a drug or a drug candidate by administering tests of the present invention to samples from patients, animal models, and cell cultures treated with a drug or a drug candidate. Also disclosed are methods for determining the usefulness of analytes, e.g. cytokines, for acting as diagnostic and monitoring markers for inflammatory bowel disease in the various methods of the invention.

    Abstract translation: 公开了用于进行诸如克罗恩病和溃疡性结肠炎的炎症性肠病的检测的诊断测试的方法。 还描述了通过管理本发明的测试来监测患者的方法。 还描述了通过管理本发明的测试来监测患者治疗的方法。 还描述了通过将本发明的试验施用于用药物或候选药物治疗的患者,动物模型和细胞培养物的样品来评价药物或药物候选物的有效性的方法。 还公开了用于确定分析物的有用性的方法,例如, 用作本发明各种方法中用于炎性肠病的诊断和监测标志物的细胞因子。

    SEROLOGY ASSAYS
    56.
    发明申请
    SEROLOGY ASSAYS 审中-公开
    血清学测定

    公开(公告)号:US20140255916A1

    公开(公告)日:2014-09-11

    申请号:US14285086

    申请日:2014-05-22

    Inventor: George Sigal

    CPC classification number: G01N33/56983 G01N33/54313 G01N33/566 G01N2500/02

    Abstract: The invention provides methods and kits for measuring the ability of a test sample to inhibit the binding of a receptor expressed by a pathogen to a host cell ligand of the pathogen.

    Abstract translation: 本发明提供了用于测量测试样品抑制由病原体表达的受体与病原体的宿主细胞配体的结合的能力的方法和试剂盒。

    GLOMERULONEPHRITIS BIOMARKERS
    58.
    发明申请
    GLOMERULONEPHRITIS BIOMARKERS 审中-公开
    GLOMERULONEPHRITIS生物标志物

    公开(公告)号:US20140221325A1

    公开(公告)日:2014-08-07

    申请号:US14168688

    申请日:2014-01-30

    CPC classification number: G01N33/6893 G01N2800/347 G01N2800/52

    Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

    Abstract translation: 本发明涉及诊断患者的肾小球肾炎(GN)的方法以及监测GN进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。

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