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    Shrinkage of dilatations in the body
    54.
    发明授权
    Shrinkage of dilatations in the body 失效
    体内扩张收缩

    公开(公告)号：US07184827B1

    公开(公告)日：2007-02-27

    申请号：US09490622

    申请日：2000-01-24

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61N1/30

    CPC classification number: A61M25/1011 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1095 ,  A61M2205/36

    Abstract: A method and system for shrinking dilatations of a body, removing excess, weak or diseased tissue, and strengthening remaining tissues of the lumen walls. A catheter is disposed near the dilatation and fixed in position by inflatable occlusion balloons. Body fluids present in the occluded dilatation are evacuated and treatment fluid is exuded under pressure into the dilatation. Pressure is maintained by the treatment fluid while energy is applied by the catheter to heat the treatment fluid, causing the lumen walls to absorb the treatment fluid. Additional energy is then applied so as to preferentially heat the lumen wall tissues which have absorbed the treatment fluid, while at the same time treatment fluid is circulated to cool the inner surface of the lumen walls. The dilatation is occluded, a saline solution is introduced and absorbed into the lumen-wall tissue in the occluded region of the dilatation and then heated by application of radio frequency (“RF”) or other energy in order to soften only the lumen-wall tissue of the dilatation, the dilatation is shrunk by application of a chilled saline solution and a vacuum, and additional RF or other energy is emitted to ablate, further shrink, and harden only the lumen-wall tissue of the dilatation, without destroying the inner surface of the lumen or other tissues of the body beyond the lumen walls, thereby promoting growth of epithelial cells.

    Abstract translation: 用于收缩身体的扩张，去除多余的，弱的或患病的组织以及加强腔壁的剩余组织的方法和系统。 导管在扩张附近设置并通过充气闭塞气球固定在适当的位置。 在闭塞扩张中存在的体液被排空，并且处理液在压力下渗出到扩张中。 在通过导管施加能量以加热处理流体的同时，通过处理流体保持压力，使得腔壁吸收处理流体。 然后施加额外的能量，以便优先加热已经吸收治疗流体的管腔壁组织，同时循环治疗流体以冷却管腔壁的内表面。 扩张被堵塞，将盐水溶液引入并吸收到扩张的闭塞区域的管腔壁组织中，然后通过施加射频（“RF”）或其他能量加热，以仅软化管腔壁 膨胀的组织，通过应用冷冻盐水溶液和真空收缩扩张，并且发射额外的RF或其他能量以消融，进一步收缩并且仅硬化扩张的管腔壁组织，而不会破坏内部 管腔或体外的其他组织的表面超过管腔壁，从而促进上皮细胞的生长。

    Sphincter treatment method
    56.
    发明授权
    Sphincter treatment method 有权
    括约肌治疗方法

    公开(公告)号：US06971395B2

    公开(公告)日：2005-12-06

    申请号：US10428458

    申请日：2003-05-02

    Applicant: Stuart D Edwards ,  David S Utley

    Inventor： Stuart D Edwards ,  David S Utley

    IPC: A61B18/14 ,  A61B19/00

    CPC classification number: A61B18/1492 ,  A61B2018/00553

    Abstract: A method of forming a composite lesion pattern in a tissue region at or near a sphincter comprising providing a catheter having a plurality of energy delivery devices coupled to the catheter. The catheter is introduced at least partially into the sphincter. Energy is delivered from the energy delivery devices to produce the composite lesion pattern. The composite lesion pattern comprises a radial distribution of lesions about the tissue region and a longitudinal distribution of lesions along the tissue region.

    Abstract translation: 在括约肌处或附近在组织区域中形成复合损伤图案的方法，包括提供具有耦合到导管的多个能量输送装置的导管。 将导管至少部分地引入括约肌。 能量从能量输送装置输送以产生复合损伤模式。 复合损伤图案包括围绕组织区域的损伤的径向分布和沿着组织区域的损伤的纵向分布。

    Treatment of discrete tissues in respiratory, urinary, circulatory, reproductive and digestive systems
    59.
    发明授权
    Treatment of discrete tissues in respiratory, urinary, circulatory, reproductive and digestive systems 有权
    治疗呼吸系统，尿液，循环系统，生殖系统和消化系统中的离散组织

    公开(公告)号：US06743197B1

    公开(公告)日：2004-06-01

    申请号：US09347441

    申请日：1999-07-02

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61M3100

    CPC classification number: A61F2/10 ,  A61B18/1492 ,  A61B2017/003 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00261 ,  A61B2018/0041 ,  A61B2018/00416 ,  A61B2018/00797 ,  A61B2090/3614 ,  A61M2025/0293 ,  A61M2025/105

    Abstract: A method and system for treating body structures or tissue allows treatment by any of ablation, coating, expansion, plumping, shaping, and shrinking. Treatment sitesinclude any of a sphincter, sinus or orifice. During treatment, electrodes emerge from apertures in a balloon. The balloon with liquid from a circulating bath cools tissue in direct contact with electrodes and immediately adjacent, so that discrete regions are treated, with minimal damage to adjacent structures. Sensors, coupled to electrodes, measure treatment properties such as: temperature, impedance and nervous activity. Measurements are used for: diagnostic assessment, determining treatment parameters, providing nervous stimulation and/or blocking, and feedback for controlling energy delivery. The catheter includes an optical path that can be coupled to external viewing apparatus. Endoscopic methods, including fluoroscopic, fiber optic, or radioscopy allow examining tissue and determining position of electrodes. The catheter includes a suction apparatus used to remove liquids obscuring treatment area and to gently conform treatment area to electrodes.

    Abstract translation: 用于治疗身体结构或组织的方法和系统允许通过消融，涂覆，膨胀，倾斜，成形和收缩中的任何一种进行治疗。 治疗部位包括任何括约肌，窦或孔。 在治疗期间，电极从气囊中的孔中出现。 具有来自循环浴的液体的球囊冷却与电极直接接触的组织，并且立即相邻，使得离散区域被处理，对相邻结构的损伤最小。 耦合到电极的传感器测量处理性能，例如：温度，阻抗和神经活动。 测量用于：诊断评估，确定治疗参数，提供神经刺激和/或阻塞，以及用于控制能量传递的反馈。 导管包括可与外部观察装置连接的光路。 内镜方法，包括荧光镜，光纤或放射检查，可以检查组织和确定电极的位置。 导管包括用于去除液体的抽吸装置，使得处理区域变得模糊，并且将处理区域轻轻地适应于电极。

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