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    Bioerodible Composites for Endoprostheses
    51.
    发明申请
    Bioerodible Composites for Endoprostheses 有权
    用于内假体的生物蚀刻复合材料

    公开(公告)号：US20150066135A1

    公开(公告)日：2015-03-05

    申请号：US14456254

    申请日：2014-08-11

    Applicant: Boston Scientific Scimed, Inc.

    Inventor： Jan Weber ,  Jacob Drew Edick

    IPC: A61L31/14 ,  C22F1/06 ,  B21C23/00 ,  A61F2/82

    CPC classification number: A61L31/148 ,  A61F2/82 ,  A61L31/124 ,  A61L2400/12 ,  B21C23/001 ,  C22F1/06

    Abstract: A bioerodible endoprosthesis includes a composite including a matrix comprising a bioerodible magnesium alloy and a plurality of ceramic nanoparticles within the matrix. The bioerodible magnesium alloy has a microstructure including equiaxed Mg-rich solid solution-phase grains having an average grain diameter of less than or equal to 5 microns. The microstructure can be produced by one or more equal-channel high-strain processes.

    Abstract translation: 生物腐蚀性内用假体包括包含基质的复合物，所述基质包含生物可腐蚀的镁合金和所述基质内的多个陶瓷纳米颗粒。 生物腐蚀性镁合金具有包括平均粒径小于或等于5微米的等轴Mg富集固相晶粒的微结构。 微结构可通过一个或多个等通道高应变过程产生。

    Kerstpiek tip for medical devices
    52.
    发明授权
    Kerstpiek tip for medical devices 有权
    医疗器械的Kerstpiek提示

    公开(公告)号：US08740842B2

    公开(公告)日：2014-06-03

    申请号：US13754175

    申请日：2013-01-30

    Applicant: Boston Scientific Scimed, Inc.

    Inventor： Jan Weber ,  James M. Anderson ,  Robert Chang

    IPC: A61M29/00

    CPC classification number: A61M25/10 ,  A61M25/0043 ,  A61M25/0068 ,  A61M25/09 ,  A61M25/1011 ,  A61M25/104 ,  A61M29/00 ,  A61M2025/1093

    Abstract: An apparatus may include a medical device including an elongate shaft disposed about a guidewire, and a distal tip including a plurality of rounded protrusions, wherein adjacent protrusions are fixed directly to each other by a discrete, relatively flexible connector. The plurality of protrusions may each decrease in size from a proximalmost protrusion distally to distalmost protrusion.

    Abstract translation: 装置可以包括医疗装置，其包括围绕导丝设置的细长轴和包括多个圆形突起的远侧末端，其中相邻的突起通过离散的相对柔性的连接器彼此直接固定。 多个突起可以从最远侧突出部到远端突出部的尺寸各自减小。

    ANTI-THROMBUS FEATURE FOR IMPLANTED MEDICAL DEVICES
    53.
    发明申请
    ANTI-THROMBUS FEATURE FOR IMPLANTED MEDICAL DEVICES 审中-公开
    用于植入医疗器械的抗血栓特征

    公开(公告)号：US20140114340A1

    公开(公告)日：2014-04-24

    申请号：US14049407

    申请日：2013-10-09

    Applicant: Boston Scientific Scimed, Inc.

    Inventor： Pu Zhou ,  Dongming Hou ,  Barbara A. Huibregtse ,  Jan Weber ,  Aiden Flanagan

    IPC: A61F2/01 ,  A61B17/12

    CPC classification number: A61F2/01 ,  A61B2017/00243 ,  A61B2017/00849 ,  A61B2017/00898 ,  A61F2/0077 ,  A61F2/2412 ,  A61F2002/009 ,  A61F2210/0061

    Abstract: A medical device for permanent implantation in a circulatory system of a patient may include an implant configured for percutaneous or minimally-invasive insertion into the patient, at least one connector fixedly attached to the implant and configured to releasably attach to a delivery device, the at least one connector being exposed to blood flow within the circulatory system following implantation, and an anti-thrombus feature configured to transition from an undeployed state to a deployed state.

    Abstract translation: 用于永久植入患者的循环系统中的医疗装置可以包括被配置用于经皮或微创入插入到患者体内的植入物，至少一个连接器固定地连接到植入物并被配置成可释放地附接到递送装置， 至少一个连接器在植入后暴露于循环系统内的血液流动，以及抗血栓特征，其构造成从未部署状态转变到展开状态。

    INJECTABLE BIODEGRADABLE PARTICLES FOR CONTROLLED THERAPEUTIC AGENT RELEASE
    54.
    发明申请
    INJECTABLE BIODEGRADABLE PARTICLES FOR CONTROLLED THERAPEUTIC AGENT RELEASE 审中-公开
    用于控制性治疗药物释放的可注射的生物可降解颗粒

    公开(公告)号：US20130323306A1

    公开(公告)日：2013-12-05

    申请号：US13899090

    申请日：2013-05-21

    Applicant: Boston Scientific Scimed, Inc.

    Inventor： Jan Weber

    IPC: A61K9/14

    CPC classification number: A61K9/146 ,  A61L31/06 ,  A61L31/16 ,  A61L2300/416 ,  A61L2400/12 ,  A61L2430/36 ,  C08L77/12

    Abstract: In accordance with one aspect, embolic particles are provided that comprise a biodegradable polymer and a therapeutic agent, wherein the particles are configured such that, upon administration to a body lumen of a subject, the therapeutic agent is released from the time of administration up until a first point in time that ranges anywhere from about 1 week after administration to about 4 weeks after administration, at which point in time the therapeutic agent release ceases. The particles are also configured such that particles remain present in the body lumen from the first point in time at which therapeutic agent release ceases up to a second point in time that ranges anywhere from about 2 weeks to about 12 months after the first point in time, at which point the particles are completely degraded. Other aspects pertain to methods of making such particles. Still other aspects pertain to injectable compositions that comprise such particles and to methods of treatment that employ such injectable compositions.

    Abstract translation: 根据一个方面，提供了包含可生物降解的聚合物和治疗剂的栓塞颗粒，其中所述颗粒构造成使得当给予受试者的体腔时，治疗剂从给药时间开始释放直至 在施用后约1周至给药后约4周的第一时间点，此时治疗剂释放停止。 颗粒还被构造成使得颗粒从治疗剂释放停止的第一时间点保持存在于体腔中，第二时间点在第一时间点之后约2周至约12个月的范围内 ，此时颗粒完全降解。 其他方面涉及制造这种颗粒的方法。 还有其它方面涉及包含这种颗粒的可注射组合物和使用这种可注射组合物的治疗方法。

    GLASS IMPELLER FOR A BLOOD PUMP
    57.
    发明公开
    GLASS IMPELLER FOR A BLOOD PUMP 审中-公开

    公开(公告)号：US20230158287A1

    公开(公告)日：2023-05-25

    申请号：US18100729

    申请日：2023-01-24

    Applicant: Boston Scientific Scimed Inc

    Inventor： Jan Weber ,  Matthew Boyer ,  Umang Anand

    IPC: A61M60/419

    CPC classification number: A61M60/419 ,  A61M2205/02

    Abstract: A blood pump includes an impeller assembly housing; and an impeller assembly disposed within the impeller assembly housing. The impeller assembly includes an impeller having a main body, at least one impeller blade extending outwardly therefrom, and a skirt disposed around at least a portion of the main body. At least a portion of the at least one impeller blade is disposed between the main body and an inner surface of the skirt.

    BANDAGE\E-TATTOO COMBINATION
    58.
    发明公开
    BANDAGE\E-TATTOO COMBINATION 审中-公开

    公开(公告)号：US20230157640A1

    公开(公告)日：2023-05-25

    申请号：US18094893

    申请日：2023-01-09

    Applicant: Boston Scientific Scimed Inc.

    Inventor： Jan Weber ,  Jeffrey E. Stahmann ,  Keith R. Maile ,  James M. Peck

    IPC: A61B5/00 ,  A61B5/1455

    CPC classification number: A61B5/6843 ,  A61B5/1455 ,  A61B5/6833 ,  A61B2562/12 ,  A61B2562/164

    Abstract: Embodiments disclosed herein relate to devices and methods for monitoring one or more physiological parameters of a subject. In an embodiment, a wearable device comprises a substrate configured to be attached to a subject's skin. The substrate comprises a middle portion arranged between two end portions. The wearable device also comprises a physiological sensor. The physiological sensor is configured to sense a physiological signal of the subject when the wearable device is attached to the subject's skin. And, the wearable device comprises one or more electrical components arranged on at least one of the end portions, wherein at least one of the one or more electrical components is coupled to the physiological sensor.

    FLEXIBLE RENAL NERVE ABLATION DEVICES AND RELATED METHODS OF USE AND MANUFACTURE
    59.
    发明申请
    FLEXIBLE RENAL NERVE ABLATION DEVICES AND RELATED METHODS OF USE AND MANUFACTURE 有权

    公开(公告)号：US20220110678A1

    公开(公告)日：2022-04-14

    申请号：US17559579

    申请日：2021-12-22

    Applicant: Boston Scientific Scimed, Inc.

    Inventor： Jan Weber ,  Jeffrey S. Lindquist

    IPC: A61B18/14

    Abstract: Medical devices for renal nerve ablation are disclosed. An example medical device for renal nerve ablation may include a catheter shaft having a distal region. The device may include an expandable member coupled to the distal region, a flexible circuit assembly coupled to the expandable member, and a pressure sensor disposed along the expandable member and positioned adjacent to the flexible circuit assembly. The flexible circuit assembly may include one or more pairs of bipolar electrodes and a temperature sensor.

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