公开(公告)号：US11892435B2

公开(公告)日：2024-02-06

申请号：US16703985

申请日：2019-12-05

Applicant: Colgate-Palmolive Company

Inventor： Chi-Yuan Cheng ,  Zhigang Hao ,  Long Pan ,  Zolijargal Balsandorj

IPC: G01N33/15 ,  G01N24/08 ,  G01N31/22 ,  G01R33/465

CPC classification number: G01N31/221 ,  G01N24/08 ,  G01R33/465

Abstract: Methods for measuring pH of gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, are provided. The method may include preparing a calibration curve of a chemical species including or having an acid dissociation constant. Preparing the calibration curve may include plotting a chemical shift of the chemical species relative to pH. The method may also include determining a chemical shift of a gel, paste, and colloid, aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, including the chemical species. The method may further include determining the pH of the gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, with the chemical shift of the product and the calibration curve.

公开(公告)号：US11344486B2

公开(公告)日：2022-05-31

申请号：US16425122

申请日：2019-05-29

Applicant: Colgate-Palmolive Company

Inventor： Baohua Qiao ,  Long Pan ,  Gregory Szewczyk ,  Ravi Subramanyam ,  Shiri Nawrocki ,  Viktor Dubovoy

IPC: A61K8/27 ,  A61K8/24 ,  A61Q15/00 ,  A61Q11/00 ,  A61K33/30 ,  A61K33/42

Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.

公开(公告)号：US11065186B2

公开(公告)日：2021-07-20

申请号：US16267424

申请日：2019-02-05

Applicant: Colgate-Palmolive Company

Inventor： Shiri Nawrocki ,  Viktor Dubovoy ,  Long Pan ,  Zhigang Hao ,  Nihal Dogu

IPC: A61K8/24 ,  A61K8/19 ,  A61Q11/00

Abstract: Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof.

公开(公告)号：US10532016B2

公开(公告)日：2020-01-14

申请号：US16213871

申请日：2018-12-07

Applicant: Colgate-Palmolive Company

Inventor： Zhigang Hao ,  Dennis Zhang ,  Donghui Wu ,  Ravi Subramanyam ,  Chi-Yuan Cheng ,  Long Pan ,  Stanislav Jaracz

IPC: A61K8/58 ,  A61Q11/00 ,  A61Q17/00 ,  A61Q15/00

Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.

公开(公告)号：US10524995B2

公开(公告)日：2020-01-07

申请号：US15964193

申请日：2018-04-27

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Shaotang Yuan ,  Shira Pilch ,  James Masters ,  Zhiqiang Liu

IPC: A61K8/44 ,  A61K8/21 ,  A61K8/27 ,  A61Q11/00

Abstract: Disclosed herein are mouthwashes comprising a complex of a zinc ion source and an amino acid. Methods of making and using the compositions are also provided.

公开(公告)号：US10195125B2

公开(公告)日：2019-02-05

申请号：US15668857

申请日：2017-08-04

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Jairajh Mattai ,  Shaotang Yuan ,  James Masters

IPC: A61K8/27 ,  A61K8/44 ,  A61Q11/00 ,  A61Q5/02 ,  A61Q19/10 ,  A61Q17/00 ,  A61Q15/00 ,  A61Q5/12 ,  C07F3/06

Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl− having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions.

公开(公告)号：US09925130B2

公开(公告)日：2018-03-27

申请号：US14653308

申请日：2012-12-19

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Jairajh Mattai ,  Shamim Ansari ,  Jianhong Qiu ,  James G. Masters ,  Ying Yang

IPC: A61K8/27 ,  A61K8/20 ,  A61K8/44 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/10 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12

CPC classification number: A61K8/27 ,  A61K8/20 ,  A61K8/44 ,  A61K2800/58 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/10

Abstract: A personal care composition for application to the skin or hair comprising a cosmetically acceptable carrier and zinc X halide precursors wherein the precursors are a zinc ion source, an X source, and a halide source, wherein the halide source can be part of the zinc ion source, the X source, or a halogen acid, wherein the precursors can complex into the zinc X halide when the composition is applied to the skin or hair, wherein X is an amino acid or trimethylglycine. Methods of making and using the compositions are also provided. When the precursors complex into a zinc X halide, the complex can be used to deliver zinc salts to block perspiration and provide antibacterial effects.

公开(公告)号：US09827177B2

公开(公告)日：2017-11-28

申请号：US14649946

申请日：2012-12-19

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Long Pan

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/64 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K8/64 ,  A61K2800/58 ,  A61K2800/874 ,  A61Q15/00

Abstract: The invention provides antiperspirant formulations comprising a protein and an antiperspirant salt in combination with a cosmetically acceptable carrier, together with methods of making and using these complexes and compositions.

公开(公告)号：US20170333311A1

公开(公告)日：2017-11-23

申请号：US15668857

申请日：2017-08-04

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Jairajh MATTAI ,  Shaotang YUAN ,  James MASTERS

IPC: A61K8/27 ,  A61Q11/00 ,  A61Q5/02 ,  A61K8/44 ,  A61Q19/10 ,  A61Q17/00 ,  A61Q15/00 ,  C07F3/06 ,  A61Q5/12

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K2800/58 ,  A61K2800/591 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  C07B2200/13 ,  C07F3/06

Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl− having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions.

公开(公告)号：US09809788B2

公开(公告)日：2017-11-07

申请号：US14649832

申请日：2012-12-07

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Diana Scala ,  Donghui Wu ,  Jairaj Mattai ,  Christine Boyke ,  Minli Shi ,  Diane Curley

IPC: C11D9/26 ,  C11D13/18 ,  C11D17/00 ,  C11D10/04

CPC classification number: C11D9/26 ,  C11D10/045 ,  C11D13/18 ,  C11D17/0017 ,  C11D17/006

Abstract: A soap bar composition comprising solid soap and an oil-in-water emulsion, wherein the emulsion comprises one or more surfactants and wherein the emulsion is dispersed within the solid soap.