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公开(公告)号：US08182446B2
公开(公告)日：2012-05-22
申请号：US12676786
申请日：2008-09-11
CPC分类号： A61M25/10 , A61M25/1027 , A61M2025/0004 , A61M2025/1013 , A61M2025/105 , A61M2025/1056
摘要： Catheter balloon assemblies (10) for delivering a therapeutic agent to a body vessel are provided, as well as related methods of manufacturing and methods of treatment. The catheter balloon assemblies may include a concentrically disposed dual balloon assembly at the distal portion of the catheter having an inner balloon (44), a porous outer balloon (42) concentrically arrayed around the inner balloon and a catheter shaft (30) adapted to deliver a therapeutic agent to the body vessel through the apertures in the outer balloon. Radial outward expansion of the inner balloon may urge the outer balloon into contact with the wall of a body vessel, where the therapeutic agent may be delivered from the catheter shaft through apertures in the outer balloon directly to the wall of the body vessel. Preferably, the catheter balloon assemblies include a stiffening′ member (210) within the proximal portion and/or a plurality of lumens lined with a fluorinated hydrocarbon to independently inflate the inner balloon, deliver the therapeutic agent through the outer balloon and house a wire guide (50). The catheter balloon assemblies may provide improved tractability and/or pushability characteristics.
摘要翻译： 提供了用于将治疗剂递送至身体血管的导管气囊组件（10），以及相关的制造方法和治疗方法。 导管球囊组件可以包括在导管的远端部分处的同心设置的双球囊组件，其具有内球囊（44），围绕内球囊同心排列的多孔外球囊（42）和适于递送的导管轴 通过外球囊中的孔，向身体血管施加治疗剂。 内球囊的径向向外膨胀可以促使外球囊与体血管的壁接触，其中治疗剂可以通过外球囊中的孔直接从导管轴输送到身体血管的壁。 优选地，导管球囊组件包括近端部分内的加强构件（210）和/或内衬有氟化烃的多个内腔，以独立地使内球囊膨胀，将治疗剂输送通过外气囊并容纳导线 （50）。 导管球囊组件可以提供改善的易处理性和/或可推动性特征。
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公开(公告)号：US08083748B2
公开(公告)日：2011-12-27
申请号：US11965431
申请日：2007-12-27
申请人： Darin G. Schaeffer
发明人： Darin G. Schaeffer
CPC分类号： A61B17/8833 , A61B17/7097 , A61B2017/8838
摘要： In at least one embodiment of the present invention, a device for mixing and dispensing a bone cement mixture is provided. The device comprises a first chamber and a second chamber. The first chamber is for containing a first bone cement component. The second chamber is for containing a second bone cement component. A valve is in fluid communication with the first and second chambers. A first and a second plunger are respectively within the first and second chambers and are configured to actuate within their respective chambers. When the valve is in a first position actuating the first plunger advances the first bone cement component into the second chamber to form the bone cement mixture.
摘要翻译： 在本发明的至少一个实施例中，提供了一种用于混合和分配骨水泥混合物的装置。 该装置包括第一室和第二室。 第一个室用于容纳第一个骨水泥组分。 第二室用于容纳第二骨水泥组分。 阀与第一和第二室流体连通。 第一和第二柱塞分别在第一和第二腔室内，并且构造成在它们各自的腔室内致动。 当阀门处于第一位置时，致动第一柱塞使第一骨粘固剂部件进入第二腔室以形成骨水泥混合物。
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公开(公告)号：US07857786B2
公开(公告)日：2010-12-28
申请号：US11926767
申请日：2007-10-29
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61M25/1038 , A61M2025/1004
摘要： The present invention provides apparatus and methods for facilitating folding of a balloon before, during or after a medical procedure. In a first embodiment, the apparatus generally comprises at least one catheter shaft member, a balloon disposed on a distal region of the catheter shaft member, and at least one folding member disposed along at least a proximal region of the balloon. The folding member may comprise at least one radially-outward projecting member integrally formed with or attached to the balloon, or an internally-formed groove in the balloon, which is adapted to promote twisting of the balloon to reduce the profile of the balloon in the deflated state. Optionally, biasing members may be disposed between the folding member and an adjacent portion of the balloon to promote folding of the balloon in a clockwise or counter-clockwise direction.
摘要翻译： 本发明提供了用于在医疗过程之前，期间或之后便于折叠气囊的装置和方法。 在第一实施例中，该装置通常包括至少一个导管轴构件，设置在导管轴构件的远侧区域上的气囊，以及沿气囊的至少近侧区域设置的至少一个折叠构件。 折叠构件可以包括与球囊一体地形成或附接到球囊上的至少一个径向向外突出的构件，或者球囊中的内部形成的凹槽，其适于促进气球的扭转，以减小球囊的轮廓 放气状态 可选地，偏压构件可以设置在折叠构件和球囊的相邻部分之间，以促进气囊沿顺时针或逆时针方向的折叠。
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公开(公告)号：US07799201B2
公开(公告)日：2010-09-21
申请号：US12732748
申请日：2010-03-26
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/00 , C25F3/16
摘要： An electropolishing apparatus and method are provided for polishing stents and other medical implants. The apparatus includes a motor that rotates a roller. The roller continuously rotates the medical implant to be electropolished. One of the advantages of the apparatus and method is that marks generated around the electrical contact between the anode and the medical implant are minimized. In addition, the medical implant is polished more evenly than conventional electropolishing systems.
摘要翻译： 提供了用于抛光支架和其他医疗植入物的电抛光装置和方法。 该装置包括使滚筒旋转的马达。 滚筒将医疗植入物连续旋转以进行电解抛光。 该装置和方法的优点之一是使阳极和医用植入物之间的电接触周围产生的标记最小化。 此外，医疗植入物比常规电抛光系统更均匀地抛光。
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公开(公告)号：US20100181206A1
公开(公告)日：2010-07-22
申请号：US12732748
申请日：2010-03-26
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/00 , C25F3/16
摘要： An electropolishing apparatus and method are provided for polishing stents and other medical implants. The apparatus includes a motor that rotates a roller. The roller continuously rotates the medical implant to be electropolished. One of the advantages of the apparatus and method is that marks generated around the electrical contact between the anode and the medical implant are minimized. In addition, the medical implant is polished more evenly than conventional electropolishing systems.
摘要翻译： 提供了用于抛光支架和其他医疗植入物的电抛光装置和方法。 该装置包括使滚筒旋转的马达。 滚筒将医疗植入物连续旋转以进行电解抛光。 该装置和方法的优点之一是使阳极和医用植入物之间的电接触周围产生的标记最小化。 此外，医疗植入物比常规电抛光系统更均匀地抛光。
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公开(公告)号：US20100023110A1
公开(公告)日：2010-01-28
申请号：US12508185
申请日：2009-07-23
申请人： Darin G. Schaeffer
发明人： Darin G. Schaeffer
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2002/821 , A61F2250/0018 , A61F2250/0039 , A61F2250/0048
摘要： An endoluminal prosthesis is disclosed and comprises a first generally tubular stent, a second generally tubular stent, and a generally tubular graft member concentrically disposed between the first and second stents. One or more of the first and second stents may have a body portion and a flaring portion. The first and second stents each may have a recoil force such that the combined application of the first and second recoil forces secures the graft member between the first and second stents.
摘要翻译： 公开了腔内假体，并且包括第一大致管状支架，第二大体管状支架和同心地设置在第一和第二支架之间的大体管状移植构件。 第一和第二支架中的一个或多个可以具有主体部分和扩口部分。 第一和第二支架各自可以具有反冲力，使得第一和第二反冲力的组合施加将移植物构件固定在第一和第二支架之间。
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公开(公告)号：US07618447B2
公开(公告)日：2009-11-17
申请号：US10828716
申请日：2004-08-30
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2002/068 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054 , A61F2230/0076 , A61F2230/0078 , A61F2230/008 , A61F2250/0037 , A61F2250/0039
摘要： An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
摘要翻译： 一种可膨胀静脉瓣，其具有支撑结构，该支撑结构被配置为扩大邻近阀结构的区域，使逆行流的流动模式以便于冲洗瓣膜区域底部的口袋的方式进行改变，以防止滞留 在静脉系统中的体液可导致血栓形成。 扩大的口袋区域可以通过在两个支撑框架部分之间的容器壁的无支撑部分中形成邻近阀结构的人造窦来形成，或者支撑框架可以包括形成邻近瓣膜的人造窦的扩张直径的中间或近端部分 结构体。 在另一组实施例中，相对的小叶与支撑框架和/或血管壁之间的附接通路包括将小叶彼此延伸接触的近端部分，并且远侧部分相对于相邻壁形成大角度， 在传单的底部创造了一个大口袋。 在一个实施例中，附接通道沿着一对基本上平行的纵向连接支柱向远侧延伸，以产生延伸的小叶接触区域，然后沿着远侧连接支柱沿着周向和远端远离成形器，以限定传单的底部边缘。
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58.发明申请公开(公告)号：US20090277385A1
公开(公告)日：2009-11-12
申请号：US12504474
申请日：2009-07-16
申请人： Brian C. Case , Darin G. Schaeffer
发明人： Brian C. Case , Darin G. Schaeffer
IPC分类号： B05C11/02
CPC分类号： A61M25/0009 , A61L27/34 , A61L29/085 , A61L31/10 , A61M2025/0046 , B05C7/02 , B05C9/14 , B05D1/26 , B05D3/06 , B05D7/222
摘要： A coating can be applied to an endolumenal wall of a medical device by positioning an optical fiber within the lumen, providing a photo-activated chemical to contact the endolumenal wall, supplying the optical fiber with radiation capable of activating the chemical within the lumen, and withdrawing the optical fiber from the lumen at a controlled rate while the radiation is being emitted from the optical fiber to activate the chemical in close proximity to the endolumenal wall.
摘要翻译： 通过将光纤定位在内腔内，可以将涂层施加到医疗器械的腔内壁，提供光致化学物质以接触内腔壁，向光纤提供能够激活管腔内的化学物质的辐射，以及 在从光纤发射辐射的同时以受控的速率从光腔中取出光纤，以激活邻近内腔壁的化学物质。
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公开(公告)号：US07252746B2
公开(公告)日：2007-08-07
申请号：US10712420
申请日：2003-11-12
申请人： Darin G. Schaeffer
发明人： Darin G. Schaeffer
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/00 , C25F3/16
摘要： An electropolishing apparatus and method are provided for polishing stents and other medical implants. The apparatus includes a motor that rotates a roller. The roller continuously rotates the medical implant to be electropolished. One of the advantages of the apparatus and method is that marks generated around the electrical contact between the anode and the medical implant are minimized. In addition, the medical implant is polished more evenly than conventional electropolishing systems.
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公开(公告)号：US09604036B2
公开(公告)日：2017-03-28
申请号：US13462458
申请日：2012-05-02
IPC分类号： A61M25/10 , A61B17/3207 , A61B17/22
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1027 , A61M25/1029 , A61M25/1038 , A61M25/104 , A61M29/02 , A61M2025/1086 , B29C49/04 , B29C49/20 , B29C2049/2017 , B29K2067/003 , B29K2077/00 , B29L2031/7543
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.
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