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公开(公告)号：US07374544B2
公开(公告)日：2008-05-20
申请号：US10335142
申请日：2002-12-31
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 mL of the fluid.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1mL的流体的样品来确定流体中的分析物的浓度。
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公开(公告)号：US20080027385A1
公开(公告)日：2008-01-31
申请号：US11539542
申请日：2006-10-06
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , G01N27/28 , G06F19/00 , G06Q50/24
摘要： A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber with a volume of less than 1 μL, The sample chambers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 μL of a body fluid disposed in the sample chamber. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
摘要翻译： 皮肤穿透系统设置有驱动力发生器和一次性外壳构件。 多个穿透构件定位在一次性外壳构件中。 每个穿透构件联接到驱动力发生器。 多个分析物检测构件各自与穿透构件相关联并且被定位在一次性外壳构件中。 每个分析物检测构件被定位在体积小于1μL的样品室中。样品室具有用于将体液输送到样品室中的开口。 每个分析物检测构件被配置为使用设置在样品室中的小于1μl体液的样品来确定体液中的分析物的浓度。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。
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公开(公告)号：US07244265B2
公开(公告)日：2007-07-17
申请号：US10335099
申请日：2002-12-31
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B17/14
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. The drive force generator is configured to be controlled to follow a predetermined velocity trajectory into the tissue and out of the tissue. A tissue stabilizing member is associated with the device and at least partially surrounds an impact location of the penetrating member on the tissue site. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
摘要翻译： 本发明的这些和其它目的在体液采集系统中实现，该体液采样系统用于组织部位，其包括驱动力发生器和可操作地联接到力发生器的穿透构件。 力产生器沿着路径将构件沿着穿过构件出口的壳体移动到组织部位中，停止在组织部位中，并从组织部位抽出。 驱动力发生器被配置为被控制以遵循预定的速度轨迹进入组织并离开组织。 组织稳定构件与装置相关联并且至少部分地围绕穿刺构件在组织部位上的冲击位置。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。
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54.发明授权Method and apparatus for a multi-use body fluid sampling device with analyte sensing 有权用于具有分析物感测的多用途体液采样装置的方法和装置公开(公告)号：US07198606B2
公开(公告)日：2007-04-03
申请号：US10323624
申请日：2002-12-18
申请人： Dirk Boecker , Dominique M. Freeman
发明人： Dirk Boecker , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： A device for use with a penetrating member driver to penetrate tissue is provided. A plurality of penetrating members are coupled to a single cartridge and are operatively couplable to the penetrating member driver. The penetrating members are movable to extend radially outward from the cartridge to penetrate tissue. A plurality of analyte sensors are coupled to the single cartridge and are positioned on the cartridge to receive body fluid from a wound in the tissue created by the penetrating member.
摘要翻译： 提供了一种用于穿透构件驱动器以穿透组织的装置。 多个穿透构件联接到单个盒，并且可操作地连接到穿透构件驱动器。 穿透构件可移动以从筒体径向向外延伸以穿透组织。 多个分析物传感器耦合到单个盒并且被定位在盒上以从穿透构件产生的组织中的伤口接收体液。
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公开(公告)号：US06966880B2
公开(公告)日：2005-11-22
申请号：US09981483
申请日：2001-10-16
CPC分类号： A61M5/142 , A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/150022 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150854 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/1519 , A61M2205/3576 , G06F19/00 , H04L67/025 , H04L67/1097 , H04L67/12 , Y10S128/903
摘要： A portable medical analyzer comprising a sampling module with a sample port for receiving body fluid, an assay sensor module for analysis of the body fluid, an analytical detector module with detection of information from the assay, and a communications module for transferring the information to a remote location via a wired or wireless network.
摘要翻译： 一种便携式医学分析仪，包括具有用于接收体液的采样端口的采样模块，用于分析体液的测定传感器模块，具有来自测定的信息检测的分析检测器模块，以及用于将信息传送到 通过有线或无线网络进行远程位置。
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公开(公告)号：US09795334B2
公开(公告)日：2017-10-24
申请号：US11774778
申请日：2007-07-09
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden , Jason Hegener
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden , Jason Hegener
CPC分类号： A61B5/15146 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14865 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/150755 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/15194 , A61B5/157 , A61B5/6886 , A61M5/3295
摘要： A tissue penetrating system has a housing member, a plurality of penetrating members positioned in the housing member and a plurality of sample chambers. Each sample chamber is associated with a penetrating member. A tissue stabilizing member has a tissue interface surface configured to be applied to a tissue surface and provide for spontaneous flow of blood for sample capture. The tissue stabilizing member is coupled to the housing.
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公开(公告)号：US09144401B2
公开(公告)日：2015-09-29
申请号：US11302423
申请日：2005-12-12
申请人： Dominique M. Freeman , Don Alden , Michael Wittig , Dirk Boecker
发明人： Dominique M. Freeman , Don Alden , Michael Wittig , Dirk Boecker
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/150022 , A61B5/150167 , A61B5/150175 , A61B5/150282 , A61B5/150427 , A61B5/150511 , A61B5/15123 , A61B5/15151 , A61B5/15161 , A61B5/411
摘要： Reducing the volume or drag on skin or sharpness of the penetrating member entering the wound during the cutting process will reduce the pain associated with lancing, and result in less power desired for retraction of the penetrating member from the skin. A variety of other penetrating member configuration as shown in the application.
摘要翻译： 减少在切割过程中进入伤口的穿透部件的皮肤或皮肤的锐度，减少与穿刺相关的疼痛，并且导致从皮肤回缩穿透部件所需的较少功率。 各种其他穿透成员配置如应用程序所示。
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公开(公告)号：US08808201B2
公开(公告)日：2014-08-19
申请号：US12014421
申请日：2008-01-15
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1μL的流体的样品来确定流体中的分析物的浓度。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。
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公开(公告)号：US08579831B2
公开(公告)日：2013-11-12
申请号：US11539542
申请日：2006-10-06
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , G01N27/28 , G06F19/00 , G06Q50/24
摘要： A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber with a volume of less than 1 μL, The sample chambers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 μL of a body fluid disposed in the sample chamber. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
摘要翻译： 皮肤穿透系统设置有驱动力发生器和一次性外壳构件。 多个穿透构件定位在一次性外壳构件中。 每个穿透构件联接到驱动力发生器。 多个分析物检测构件各自与穿透构件相关联并且被定位在一次性外壳构件中。 每个分析物检测构件被定位在体积小于1μL的样品室中。样品室具有用于将体液输送到样品室中的开口。 每个分析物检测构件被配置为使用设置在样品室中的小于1μl体液的样品来确定体液中的分析物的浓度。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。
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公开(公告)号：US08403864B2
公开(公告)日：2013-03-26
申请号：US11417312
申请日：2006-05-01
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
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