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    CHRONICALLY-IMPLANTABLE ACTIVE FIXATION MEDICAL ELECTRICAL LEADS AND RELATED METHODS FOR NON-FLUOROSCOPIC IMPLANTATION
    54.
    发明申请
    CHRONICALLY-IMPLANTABLE ACTIVE FIXATION MEDICAL ELECTRICAL LEADS AND RELATED METHODS FOR NON-FLUOROSCOPIC IMPLANTATION 有权
    慢性植入式有源固定型医用电线及相关方法非手术植入

    公开(公告)号：US20100004724A1

    公开(公告)日：2010-01-07

    申请号：US12492906

    申请日：2009-06-26

    申请人： H. Toby Markowitz ,  Chad Giese ,  Steven L. Waldhauser

    发明人： H. Toby Markowitz ,  Chad Giese ,  Steven L. Waldhauser

    IPC分类号： A61N1/05

    CPC分类号： A61N1/056 ,  A61N1/0573 ,  A61N1/08

    摘要： Bio-impedance may be used for navigation systems to chronically implant pacing and defibrillation leads in the heart using anon-fluoroscopic position sensing unit (PSU), such as a modified LocaLisa® system from Medtronic Inc., which allows for variable frequency sampling of the position of electrode of a catheter. The PSU injects small AC signals via surface electrodes in three orthogonal axes, each on a slightly different frequency (e.g., near 30 KHz). Indwelling electrodes electrically connected to the PSU resolves the magnitude of induced voltage for each of the three frequencies, thus measuring voltage for each of the three axes. Voltages are divided by induced current to yield impedance in each axis for each electrode. Impedance is proportional to position within the body. Such a system requires that a conductive material, such as a retractable helical tip-electrode, be exposed during implantation. Since the tip is retracted during implantation, this disclosure provides a modified distal portion employing at least one aperture (or “window”) for fluid exposure of the helix-electrode and a deployable internal sleeve for covering the aperture(s) when the helix-electrode is extended.

    摘要翻译： 生物阻抗可用于导航系统，以使用例如美敦力公司（Medtronic Inc.）的经修改的LocaLisa系统从心脏中长期植入心脏起搏和除颤引线，该系统允许可变频率采样 的导管的电极的位置。 PSU通过三个正交轴中的表面电极注入小的AC信号，每个在稍微不同的频率（例如，接近30KHz）处。 电连接到PSU的留置电极解决三个频率中的每一个的感应电压的大小，从而测量三个轴中的每一个的电压。 电压被感应电流除以每个电极的每个轴线产生阻抗。 阻抗与体内的位置成比例。 这样的系统需要在植入期间露出诸如可伸缩螺旋尖端电极的导电材料。 由于尖端在植入期间缩回，本公开提供了一种改进的远侧部分，其采用至少一个用于螺旋电极的流体暴露的孔口（或“窗口”），以及可展开的内部套筒， 电极延长。

    Chronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation
    55.
    发明授权
    Chronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation 有权
    长期植入式主动固定医用电线和相关方法用于非荧光镜植入

    公开(公告)号：US08135467B2

    公开(公告)日：2012-03-13

    申请号：US12492906

    申请日：2009-06-26

    申请人： H. Toby Markowitz ,  Chad Giese ,  Steven L. Waldhauser

    发明人： H. Toby Markowitz ,  Chad Giese ,  Steven L. Waldhauser

    IPC分类号： A61N1/00

    CPC分类号： A61N1/056 ,  A61N1/0573 ,  A61N1/08

    摘要： Bio-impedance may be used for navigation systems to chronically implant pacing and defibrillation leads in the heart using a non-fluoroscopic position sensing unit (PSU). Such a system requires that a conductive material, such as a retractable helical tip-electrode, be exposed during implantation. Since the tip is retracted during implantation, this disclosure provides a modified distal portion employing at least one aperture (or “window”) for fluid exposure of the helix-electrode and a deployable internal sleeve for covering the aperture(s) when the helix-electrode is extended.

    摘要翻译： 生物阻抗可用于导航系统，以使用非荧光位置感测单元（PSU）在心脏中长期植入起搏和除颤引线。 这样的系统需要在植入期间露出诸如可伸缩螺旋尖端电极的导电材料。 由于尖端在植入期间缩回，本公开提供了一种改进的远侧部分，其采用至少一个用于螺旋电极的流体暴露的孔口（或“窗口”），以及可展开的内部套筒， 电极延长。

    System and method to evaluate electrode position and spacing
    57.
    发明授权
    System and method to evaluate electrode position and spacing 有权
    评估电极位置和间距的系统和方法

    公开(公告)号：US07941213B2

    公开(公告)日：2011-05-10

    申请号：US12183796

    申请日：2008-07-31

    申请人： H. Toby Markowitz ,  Phillip Falkner ,  Douglas A. Hettrick ,  Sameh Sowelam

    发明人： H. Toby Markowitz ,  Phillip Falkner ,  Douglas A. Hettrick ,  Sameh Sowelam

    IPC分类号： A61N1/00

    CPC分类号： A61N1/05 ,  A61N1/3706

    摘要： An IMD can be implanted into a patient to address various conditions. The IMD case and leads can have various electrodes and other portions to measure various physiological conditions. For example, a selected current can be generated between two electrodes, either external or internal in the patient, and a voltage can be measured by one or more electrodes of the IMD. A voltage can be measured at two or more locations to determine a relative motion of different electrodes. If the electrodes are in different portions of the heart, a determination can be made of a relative motion or position of the heart or portions of the heart.

    摘要翻译： 可以将IMD植入患者中以解决各种情况。 IMD外壳和引线可以具有各种电极和其他部分来测量各种生理条件。 例如，可以在患者的外部或内部的两个电极之间产生所选择的电流，并且可以通过IMD的一个或多个电极来测量电压。 可以在两个或更多个位置处测量电压以确定不同电极的相对运动。 如果电极位于心脏的不同部分，则可以确定心脏或心脏部分的相对运动或位置。

    SYSTEM AND METHOD TO EVALUATE ELECTRODE POSITION AND SPACING
    58.
    发明申请
    SYSTEM AND METHOD TO EVALUATE ELECTRODE POSITION AND SPACING 有权
    用于评估电极位置和间隔的系统和方法

    公开(公告)号：US20090093857A1

    公开(公告)日：2009-04-09

    申请号：US12183796

    申请日：2008-07-31

    申请人： H. Toby Markowitz ,  Phillip Falkner ,  Douglas A. Hettrick ,  Sameh Sowelam

    发明人： H. Toby Markowitz ,  Phillip Falkner ,  Douglas A. Hettrick ,  Sameh Sowelam

    IPC分类号： A61N1/368

    CPC分类号： A61N1/05 ,  A61N1/3706

    摘要： An IMD can be implanted into a patient to address various conditions. The IMD case and leads can have various electrodes and other portions to measure various physiological conditions. For example, a selected current can be generated between two electrodes, either external or internal in the patient, and a voltage can be measured by one or more electrodes of the IMD. A voltage can be measured at two or more locations to determine a relative motion of different electrodes. If the electrodes are in different portions of the heart, a determination can be made of a relative motion or position of the heart or portions of the heart.

    摘要翻译： 可以将IMD植入患者中以解决各种情况。 IMD外壳和引线可以具有各种电极和其他部分来测量各种生理条件。 例如，可以在患者的外部或内部的两个电极之间产生所选择的电流，并且可以通过IMD的一个或多个电极来测量电压。 可以在两个或更多个位置处测量电压以确定不同电极的相对运动。 如果电极位于心脏的不同部分，则可以确定心脏或心脏部分的相对运动或位置。