4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives as antitumor agents
    53.
    发明授权
    4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives as antitumor agents 失效
    4-氧杂-1-氮杂双环[3,2,0]庚-7-酮衍生物作为抗肿瘤剂

    公开(公告)号:US5561126A

    公开(公告)日:1996-10-01

    申请号:US362490

    申请日:1995-03-16

    CPC分类号: A61K31/42

    摘要: The present invention relates to the use of 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents. ##STR1## Wherein R is --OCOR.sub.1 group wherein R.sub.1 is hydrogen atom, a C.sub.1-9 alkyl group which may be substituted by either one or two substituents selected together from halogen atom, hydroxy, carboxy group or (3RS,5SR)-(4-oxo-1-azabicyclo[3,2,0]heptan-7-one-3-yl) methyloxycarbonyl, a C.sub.2-17 alkenyl group, which may be substituted by carboxy group or (3RS,5SR)-(4-oxa-1-azabicyclo [3,2,0]heptan-7-one-3-yl)methyloxycarbonyl, A C.sub.2-4 alkynyl group, a C.sub.3-6 cycloalkyl group which may be substituted by carboxy group or phenyl group which may have 1, 2 or 3 substituents selected from the group consisting of cyano group, halogen atom, C.sub.1-6 alkoxy group which may be substituted by carboxy group, C.sub.1-6 alkyl group, amino group or hydroxy group.--OR.sub.2 wherein R.sub.2 is a hydrogen atom or benzyl group which may be substituted by 1 or 2 C.sub.1-6 alkoxy group.--S(O).sub.n R.sub.3 wherein R.sub.3 is phenyl group or a benzyl group which may be substituted by C.sub.1-6 alkyl group, n is 0, 1, or 2;or --CH.sub.2 OH.

    摘要翻译: PCT No.PCT / GB93 / 01435 Sec。 371日期1995年3月16日 102(e)1995年3月16日PCT PCT 1993年7月8日PCT公布。 公开号WO94 / 01109 1994年1月20日的日本本发明涉及式(I)的4-氧杂-1-氮杂双环[3,2,0]庚-7-酮衍生物或其药学上可接受的盐作为抗肿瘤剂。 (I)其中R是-OCOR1基团,其中R1是氢原子,可以被一个或两个选自卤原子,羟基,羧基或(3RS,5SR)的取代基取代的C1-9烷基, - (4-氧代-1-氮杂双环[3,2,0]庚-7-酮-3-基)甲氧基羰基,可被羧基取代的C 2-7烯基或(3RS,5SR) - ( 4-氧杂-1-氮杂双环[3,2,0]庚-7-酮-3-基)甲氧基羰基,C 2-4炔基,可被羧基或苯基取代的C 3-6环烷基, 可以具有1,2或3个选自氰基,卤素原子,可被羧基,C 1-6烷基,氨基或羟基取代的C 1-6烷氧基的取代基。 -OR 2,其中R 2是可被1或2个C 1-6烷氧基取代的氢原子或苄基。 -S(O)n R 3,其中R 3是苯基或可被C 1-6烷基取代的苄基,n是0,1或2; 或-CH 2 OH。

    Thin film magnetic head with protrusion heater and temperature correcting resistor
    56.
    发明授权
    Thin film magnetic head with protrusion heater and temperature correcting resistor 有权
    带突起加热器和温度校正电阻的薄膜磁头

    公开(公告)号:US07929256B2

    公开(公告)日:2011-04-19

    申请号:US11940003

    申请日:2007-11-14

    IPC分类号: G11B5/56

    摘要: A thin film magnetic head is disclosed that is capable of preventing the contact between an element portion and a recording medium and a variation in the amount of protrusion of the element portion. A thin film magnetic head includes: a reproducing element; a recording element that is formed on the reproducing element; a heater that is supplied with power and generates heat to expand at least one of the reproducing element and the recording element such that the reproducing element and/or the recording element protrude toward a recording medium; and a temperature correcting resistor that is connected in parallel to the heater and has a negative resistance temperature coefficient.

    摘要翻译: 公开了一种薄膜磁头,其能够防止元件部分和记录介质之间的接触以及元件部分的突出量的变化。 薄膜磁头包括:再现元件; 形成在再现元件上的记录元件; 加热器,其被供电并产生热量以扩展再现元件和记录元件中的至少一个,使得再现元件和/或记录元件朝向记录介质突出; 以及与加热器并联连接并具有负电阻温度系数的温度校正电阻器。

    LIQUID COMPOSITION, SET, LIQUID CARTRIDGE, INKJET RECORDING METHOD, AND INKJET RECORDING APPARATUS
    57.
    发明申请
    LIQUID COMPOSITION, SET, LIQUID CARTRIDGE, INKJET RECORDING METHOD, AND INKJET RECORDING APPARATUS 有权
    液体组合物,套装,液体盒,喷墨记录方法和喷墨记录装置

    公开(公告)号:US20110057994A1

    公开(公告)日:2011-03-10

    申请号:US12874964

    申请日:2010-09-02

    IPC分类号: B41J2/05 C09D11/02 B41J2/175

    CPC分类号: C09D11/40 C09D11/30

    摘要: A liquid composition used in combination with an ink containing a coloring material is ejected by the action of thermal energy from a recording head including a heating resistor having a protecting layer that is to come into contact with the liquid composition and that contains at least one of a metal and a metal oxide. The liquid composition contains at least either an organic compound having a carboxy group and an amino group or an amine oxide compound, an organic acid having a carboxy group, and water.

    摘要翻译: 与含有着色材料的油墨组合使用的液体组合物通过来自包括具有与液体组合物接触的保护层的加热电阻器的记录头的热能的作用喷射,并且包含至少一种 金属和金属氧化物。 液体组合物至少含有具有羧基和氨基的有机化合物或氧化胺化合物,具有羧基的有机酸和水。