MEDICAL COPOLYMERS
    54.
    发明申请
    MEDICAL COPOLYMERS 有权
    医用共聚物

    公开(公告)号:US20090324679A1

    公开(公告)日:2009-12-31

    申请号:US12491467

    申请日:2009-06-25

    IPC分类号: A61F2/00 A61K9/14

    摘要: According to an aspect of the present invention, medical copolymers are provided which comprise (a) a polymer backbone comprising (i) a plurality of —C═C— groups within the polymer backbone, (ii) a plurality of -R9- groups within the polymer backbone, wherein R9 comprises a radical-substituted C2-C10 cyclic or heterocyclic group, or (iii) both a plurality of —C═C— groups and a plurality of -R9- groups within the polymer backbone (b) a plurality of hydrocarbon-based pendant groups along the polymer backbone that comprise a saturated or unsaturated carbon chain of at least four carbons in length, and (c) a plurality of zwitterionic pendant groups along the polymer backbone that comprise a positively charged quaternary ammonium group and a negatively charged phosphate group. Further aspects of the invention, among others, relate to methods of forming such copolymers, medical products that contain such copolymers, and methods of making such medical products.

    摘要翻译: 根据本发明的一个方面,提供了医用共聚物,其包含(a)聚合物主链,其包含(i)聚合物主链内的多个-CC-基团,(ii)聚合物内的多个-R9-基团 骨架,其中R9包含自由基取代的C 2 -C 10环状或杂环基团,或(iii)聚合物主链(b)中的多个-CC-基团和多个-R9-基团,多个烃基 沿聚合物主链的侧基包含长度为至少四个碳原子的饱和或不饱和碳链,以及(c)沿聚合物主链的多个两性离子侧基,其包含带正电荷的季铵基和带负电荷的磷酸基 。 本发明的其它方面尤其涉及形成这种共聚物的方法,含有这种共聚物的医药产品,以及制备这种医药产品的方法。