Drug eluting medical devices having porous layers
    5.
    发明授权
    Drug eluting medical devices having porous layers 有权
    具有多孔层的药物洗脱医学装置

    公开(公告)号:US08815273B2

    公开(公告)日:2014-08-26

    申请号:US11881749

    申请日:2007-07-27

    IPC分类号: A61F13/00 A61F2/06

    摘要: In accordance with an aspect of the invention, implantable or insertable medical devices are provided that comprise (a) a substrate and (b) a porous layer comprising close packed spherical pores disposed over the substrate. The porous layer may also comprise a therapeutic agent. In another aspect, the present invention provides methods of forming implantable or insertable medical devices. These methods comprise forming a predecessor structure that comprises (i) a substrate over which is disposed (ii) an assembly of microspheres. This assembly of microspheres is then used as a template for the formation of a porous layer, which may be subsequently loaded with a therapeutic agent.

    摘要翻译: 根据本发明的一个方面,提供了可植入或可插入的医疗装置,其包括(a)基底和(b)包含设置在基底上的紧密堆积的球形孔的多孔层。 多孔层还可以包含治疗剂。 在另一方面,本发明提供了形成可植入或可插入的医疗装置的方法。 这些方法包括形成前身结构,其包括(i)在其上设置(ii)微球组件的基底。 然后将该微球体组合物用作形成多孔层的模板,随后可以加入治疗剂。