Apparatus and method to pretreat and sterilize a lumen device
    51.
    发明授权
    Apparatus and method to pretreat and sterilize a lumen device 失效
    预处理和消毒管腔装置的装置和方法

    公开(公告)号:US06589481B1

    公开(公告)日:2003-07-08

    申请号:US09222966

    申请日:1998-12-30

    IPC分类号: A61L200

    摘要: Various forms of apparatus and methods for pretreating and sterilizing a lumen with a peroxide solution prior to sterilization of the interior of the lumen by exposing the lumen to reduced pressure and, optionally, plasma in a sterilization chamber. The pretreatment is preferably done before placing the lumen in the sterilization chamber. The method also includes exposure of the exterior of the lumen to peroxide vapor to sterilize the exterior of the lumen. Pretreatment of the interior of the lumen with liquid peroxide greatly improves the efficiency of sterilization of the interior. Exposure of the lumen to plasma reduces the time required for sterilization.

    摘要翻译: 在通过使内腔暴露于减压之前,以及任选地在灭菌室中的等离子体之前,用过氧化物溶液预处理和消毒内腔内部的内部的各种形式的装置和方法。 预处理优选在将内腔置于灭菌室内之前进行。 该方法还包括将内腔的外部暴露于过氧化物蒸气以对管腔的外部进行灭菌。 用液体过氧化物预处理内腔内部,大大提高了内部灭菌的效率。 将内腔暴露于血浆减少了灭菌所需的时间。

    Sterilization process using small amount of sterilant to determine the load
    53.
    发明授权
    Sterilization process using small amount of sterilant to determine the load 有权
    消毒过程中使用少量灭菌剂来确定负荷

    公开(公告)号:US06333002B1

    公开(公告)日:2001-12-25

    申请号:US09223125

    申请日:1998-12-30

    IPC分类号: G05B200

    摘要: A method for determining and sterilizing a load in a sterilization chamber. A small amount of sterilant is introduced into the sterilization chamber and the concentration of sterilant is measured. The load of equipment to be sterilized is determined from the concentration of sterilant, and more sterilant is added, if necessary, based on the load. The process is repeated, if necessary, until the load is sterilized. The sterilant is preferably hydrogen peroxide, and the concentration of hydrogen peroxide is preferably determined by a spectrophotometric method in the infrared or ultraviolet regions. By monitoring the sterilant concentration and adding more as needed, the equipment in the chamber can be sterilized efficiently without exposing it to high concentrations of sterilant which could damage the equipment or leave too much residual on the equipment.

    摘要翻译: 一种用于确定和消毒灭菌室中的负载的方法。 将少量灭菌剂引入消毒室中,并测量灭菌剂的浓度。 要灭菌的设备的负荷由灭菌剂的浓度确定,如果需要,根据负载添加更多的灭菌剂。 如果需要,重复该过程,直到负载消毒。 杀菌剂优选为过氧化氢,优选通过分光光度法在红外线或紫外线区域中确定过氧化氢的浓度。 通过监测灭菌剂浓度并根据需要添加更多,室内的设备可以高效灭菌,而不会将其暴露于高浓度的灭菌剂,这可能会损坏设备或在设备上留下太多的残留物。

    Method and apparatus for measuring the concentration of hydrogen peroxide vapor
    55.
    发明授权
    Method and apparatus for measuring the concentration of hydrogen peroxide vapor 有权
    用于测量过氧化氢蒸汽浓度的方法和装置

    公开(公告)号:US06269680B1

    公开(公告)日:2001-08-07

    申请号:US09337727

    申请日:1999-06-21

    IPC分类号: G01N2135

    摘要: An improved apparatus and method for measuring the concentration of hydrogen peroxide vapor or gas in a sterilization chamber. The hydrogen peroxide is measured spectrophotometrically in the ultraviolet region between 200 and 400 nm. Because water vapor does not absorb in the ultraviolet region, it does not interfere with the determination of the concentration of the hydrogen peroxide vapor. Although organic compounds have absorbances in the ultraviolet region, the organic compounds are removed by evacuating the sterilization chamber to low levels before doing the hydrogen peroxide determination. The ultraviolet light source is either a low pressure mercury vapor lamp with an emission at 254 nm or a deuterium lamp with an optical filter selective of 206 nm light. A movable gas cell can be used to measure the hydrogen peroxide concentration at various areas in the sterilization chamber. The measurement system can be combined with a feedback loop to control the concentration of hydrogen peroxide in the sterilization chamber.

    摘要翻译: 一种用于测量灭菌室中过氧化氢蒸汽或气体浓度的改进的装置和方法。 在200和400nm之间的紫外线区域,用分光光度法测量过氧化氢。 由于水蒸汽在紫外线区域不吸收,因此不会影响过氧化氢蒸汽浓度的测定。 虽然有机化合物在紫外线区域具有吸光度,但是在进行过氧化氢测定之前,通过将消毒室排空至低水平来除去有机化合物。 紫外线光源是发射在254nm的低压汞蒸气灯或具有选择性为206nm光的滤光器的氘灯。 可移动气室可用于测量灭菌室中各个区域的过氧化氢浓度。 测量系统可以与反馈回路结合,以控制灭菌室中过氧化氢的浓度。

    Integrated cleaning sterilization process
    56.
    发明授权
    Integrated cleaning sterilization process 失效
    综合清洗灭菌工艺

    公开(公告)号:US06203756B1

    公开(公告)日:2001-03-20

    申请号:US08992478

    申请日:1997-12-17

    IPC分类号: A61L900

    摘要: A method for cleaning and sterilizing a medical device comprises the steps of: a) placing the device into a container, b) cleaning the device with a cleaning solution, c) rinsing the device with rinse solution, d) treating the device with a liquid sterilant, e) vaporizing the liquid sterilant in the container thereby simultaneously sterilizing and drying the device, and providing a sterile, dry product without further rinsing. The method further comprises retaining a predetermined amount of the liquid sterilant in the container prior to step e). Step e) can be conducted under a diffusion restricted environment, or by reducing pressure to a first predetermined pressure followed by further reducing the first pressure to a predetermined second pressure, or at controlled pump down rate.

    摘要翻译: 一种用于医疗装置的清洁和消毒的方法包括以下步骤:a)将装置放置在容器中,b)用清洁溶液清洁装置,c)用冲洗溶液冲洗装置,d)用液体 消毒剂,e)使容器中的液体灭菌剂蒸发,从而同时对该装置进行灭菌和干燥,并提供无菌干燥的产品,无需进一步漂洗。 该方法还包括在步骤e)之前将预定量的液体灭菌剂保持在容器中。 步骤e)可以在扩散受限的环境下进行,或者通过将压力降低到第一预定压力,然后进一步将第一压力降低到预定的第二压力,或以受控的抽空率进行。