公开(公告)号：US6090910A

公开(公告)日：2000-07-18

申请号：US984538

申请日：1997-12-03

申请人： Hosei Shinoda ,  Masanobu Ajioka

发明人： Hosei Shinoda ,  Masanobu Ajioka

IPC分类号： A61L17/12 ,  D01F6/84 ,  C08G63/08 ,  A61L17/00 ,  C08G63/88 ,  D02J1/22

CPC分类号： D01F6/84 ,  A61L17/12

摘要： A degradable copolymer filament comprising an internal structure having the following separate phases: (a) a matrix phase comprised as a primary component of a polymer segment which exhibits a tensile Young's modulus of 2 GPa or less and a strength retention of 50% or more after two weeks in water at 37.degree. C., pH 7.3, and (b) a micro-dispersed phase comprised as a primary component of a polymer segment which exhibits a tensile strength of 200 MPa or more and a strength reduction greater than the matrix phase in water at 37.degree. C., pH 7.3. The weight ratio of each component in the matrix phase and dispersed phase is 50:50 to 95:5, respectively, and the dispersed phase a needle structure oriented by stretching in the fiber direction. A degradable monofilament having an excellent mechanical strength and flexibility, moderate hydrolyzability, high ligature stability and being suitable as a material of surgical absorbable suture can be obtained. A preparation process is also provided.

摘要翻译： 一种可降解共聚物长丝，其包含具有以下分离相的内部结构：（a）基质相，其包含作为聚合物链段的主要组分，其显示出2GPa或更小的拉伸杨氏模量和50％以上的强度保持率 在37℃，pH7.3的水中两周，和（b）包含作为聚合物链段的主要组分的微分散相，其表现出200MPa或更大的拉伸强度，并且强度降低大于基体相 在37℃，pH 7.3的水中。 基体相和分散相中各成分的重量比分别为50:50〜95:5，分散相为沿纤维方向拉伸取向的针状结构。 可以获得具有优异的机械强度和柔韧性，适度的水解性，高韧带稳定性并且适合作为手术可吸收缝合材料的可降解单丝。 还提供了一个准备过程。

公开(公告)号：US5955402A

公开(公告)日：1999-09-21

申请号：US15212

申请日：1998-01-29

申请人： Masakazu Hirata ,  Mari Kataoka ,  Shoji Obuchi ,  Masanobu Ajioka

发明人： Masakazu Hirata ,  Mari Kataoka ,  Shoji Obuchi ,  Masanobu Ajioka

IPC分类号： C08L67/02 ,  C08L67/04 ,  F16C33/20 ,  C10M107/32 ,  C10M171/04

CPC分类号： F16C33/201 ,  C08L67/02 ,  C08L67/04 ,  C10M2201/00 ,  C10M2201/041 ,  C10M2201/042 ,  C10M2201/061 ,  C10M2201/065 ,  C10M2201/066 ,  C10M2201/08 ,  C10M2201/081 ,  C10M2201/082 ,  C10M2201/084 ,  C10M2201/102 ,  C10M2201/105 ,  C10M2201/16 ,  C10M2201/18 ,  C10M2209/102 ,  C10N2240/02

摘要： A biodegradable lubricative resin composition which withstands use as a material for sliding parts, and slide bearings and gears made from such a resin composition. The resin composition contains an aliphatic polyester which is a monopolymer or copolymer of a hydroxy-carboxylic acid or an aliphatic polyhydroxy alcohol and an aliphatic polybase, the aliphatic polyester preferably containing 50-100 wt % lactic acid, and a lubricant which is a lubricating oil or a solid lubricant. Slide bearings and gears molded from such a resin composition are also proposed.

摘要翻译： 一种可用作滑动部件材料的可生物降解的润滑树脂组合物，并且滑动由这种树脂组合物制成的轴承和齿轮。 树脂组合物含有作为羟基羧酸或脂肪族多羟基醇的单体或共聚物的脂肪族聚酯和脂肪族聚酯，脂肪族聚酯优选含有50〜100重量％的乳酸，润滑剂为润滑油 或固体润滑剂。 还提出了由这种树脂组合物模制的滑动轴承和齿轮。

公开(公告)号：US5763513A

公开(公告)日：1998-06-09

申请号：US434540

申请日：1995-05-04

申请人： Kazuhiko Suzuki ,  Takayuki Watanabe ,  Yasuhiro Kitahara ,  Masanobu Ajioka ,  Shuhei Ikado

发明人： Kazuhiko Suzuki ,  Takayuki Watanabe ,  Yasuhiro Kitahara ,  Masanobu Ajioka ,  Shuhei Ikado

IPC分类号： C08K3/36 ,  C08K5/103 ,  C08K5/11 ,  C08K5/20

CPC分类号： C08K5/11 ,  C08K3/36 ,  C08K5/103 ,  C08K5/20

摘要： A lactic acid polymer composition comprising formulating 100 parts by weight of a mixture consisting of 80-95% by weight of an L-lactic acid polymer having an L-lactic acid proportion of 75% or more and 5-20% by weight of a plasticizer selected from the group consisting of a polyhydric alcohol ester and a hydroxypolycarboxylic acid ester, 0.1-5 parts by weight of an anti-bloking agent having a SiO.sub.2 content of 90% or more and an average particle size of 7-50 nm, and 0.1-2 parts by weight of a slip agent; a molded product and film obtained from the composition; and a preparation process of the same are disclosed. The molded product and film are excellent in processability, transparency, flexibility, anti-blocking property and slip, and can be degraded into harmless water and carbon dioxide under natural environment, when abandoned.

摘要翻译： 一种乳酸聚合物组合物，其包含配制100重量份的由80-95重量％的L-乳酸比例为75％以上的L-乳酸聚合物和5-20重量％的由 选自多元醇酯和羟基多羧酸酯的增塑剂，0.1-5重量份SiO 2含量为90％以上，平均粒径为7-50nm的抗血清剂，以及 0.1-2重量份的滑爽剂; 由该组合物获得的成型品和膜; 并公开了其制备方法。 成型品和膜的加工性，透明性，柔软性，防粘连性和滑爽性优异，在被废弃时可以在自然环境下降解成无害的水和二氧化碳。

公开(公告)号：US5747637A

公开(公告)日：1998-05-05

申请号：US697571

申请日：1996-08-28

申请人： Hosei Shinoda ,  Masanobu Ajioka ,  Kimitaka Chida

发明人： Hosei Shinoda ,  Masanobu Ajioka ,  Kimitaka Chida

IPC分类号： A61L17/12 ,  C08G63/08

CPC分类号： C08G63/08 ,  A61L17/12

摘要： A bioabsorbable, ternary block copolymer consisting essentially of (A) polylactic acid segment, (B) poly(.epsilon.-caprolactone) segment and (C) polyglycolic acid segment, preparation process of the block copolymer, and medical molded articles prepared from said block copolymer. The bioabsorbable block copolymer is excellent in mechanical strength and flexibility and has moderate hydrolyzability and is especially utilized for a surgical monofilament suture.

摘要翻译： 主要由（A）聚乳酸链段，（B）聚（ε-己内酯）链段和（C）聚乙醇酸链段组成的生物可吸收的三元嵌段共聚物，嵌段共聚物的制备方法和由所述嵌段共聚物 。 生物可吸收嵌段共聚物的机械强度和柔韧性优异，具有适度的水解性，特别适用于手术单丝缝合。

公开(公告)号：US5714230A

公开(公告)日：1998-02-03

申请号：US340902

申请日：1994-11-15

申请人： Taiji Kameoka ,  Takeshi Kashima ,  Masanobu Ajioka ,  Akihiro Yamaguchi ,  Kazuhiko Suzuki

发明人： Taiji Kameoka ,  Takeshi Kashima ,  Masanobu Ajioka ,  Akihiro Yamaguchi ,  Kazuhiko Suzuki

IPC分类号： B32B27/10 ,  B32B27/36 ,  C08G63/16 ,  C08G63/60 ,  C08G63/81 ,  C08L67/00 ,  C08L67/02 ,  D04H1/42 ,  D04H13/00 ,  D06N7/04 ,  B32B00/00

CPC分类号： C08L67/02 ,  B32B27/10 ,  B32B27/36 ,  C08G63/16 ,  C08G63/60 ,  C08G63/81 ,  C08L67/00 ,  D04H1/4258 ,  D04H1/435 ,  C08L2201/06 ,  Y10T428/24355 ,  Y10T428/249921 ,  Y10T428/2913 ,  Y10T428/3179

摘要： Formed products such as foams, fabrics for industrial materials, filaments, nonwoven fabrics, composite materials and films which are degradable after use with ease in the natural environment are prepared by using a high molecular weight aliphatic polyester obtained by direct polycondensation of an aliphatic polyhydric alcohol with aliphatic polybasic acid or additionally hydroxycarboxylic acid or oligomers of these materials in a reaction mixture containing a solvent. Foams have excellent thermal insulation and strength; fabrics are excellent in thermal insulation, strength and elongation and can be used for industrial materials; filaments have sufficient strength, flexibility and degradability in a living body and can be used for bioabsorbable surgical filament and fishing lines; nonwoven fabrics can be obtained by bonding a web of filaments and have excellent strength and feeling; composite materials can be prepared by adhering or impregnating fiber, paper, film and others of cellulosics and have excellent strength and water resistance, good flexibility and folding resistance, simultaneously have degradability in the natural environment, and can dissolve polymer films on the surface with ease under alkaline conditions to recover cellulosics alone; and films are excellent in heat resistance and strength.

公开(公告)号：US5556711A

公开(公告)日：1996-09-17

申请号：US380311

申请日：1995-01-30

申请人： Masanobu Ajioka ,  Katashi Enomoto ,  Akihiro Yamaguchi ,  Kazuhiko Suzuki

发明人： Masanobu Ajioka ,  Katashi Enomoto ,  Akihiro Yamaguchi ,  Kazuhiko Suzuki

IPC分类号： B32B15/08 ,  B32B15/09 ,  B32B27/36 ,  C08L67/04 ,  B32B27/42

CPC分类号： B32B15/08 ,  Y10T428/1355 ,  Y10T428/31678 ,  Y10T428/31688

摘要： A multilayer composite consisting of aluminum and a resin composition primarily comprising a lactic acid base polymer, is disclosed. The composite material is excellent in mechanical and gas barrier properties and has characteristic of totally decomposing under alkaline conditions.

摘要翻译： 公开了一种由铝和主要包含乳酸基聚合物的树脂组合物组成的多层复合材料。 复合材料的机械和气体阻隔性能优异，具有在碱性条件下完全分解的特点。

公开(公告)号：US5461085A

公开(公告)日：1995-10-24

申请号：US357163

申请日：1994-12-13

申请人： Akinori Nagatomo ,  Hiroaki Tamatani ,  Masanobu Ajioka ,  Akihiro Yamaguchi

发明人： Akinori Nagatomo ,  Hiroaki Tamatani ,  Masanobu Ajioka ,  Akihiro Yamaguchi

IPC分类号： C08G69/10 ,  C08G69/48 ,  C08G73/10 ,  C07D243/00 ,  C08J9/36

CPC分类号： C08G69/10 ,  C08G69/48 ,  C08G73/1092

摘要： A process for preparing a novel superabsorbent polymer which is readily hydrolyzed and conform to environment by reacting a polysuccinimide with a diamine in an aqueous solution or an organic solvent to partially crosslink the polysuccinimide, and subsequently or concurrently hydrolyzing the remaining imide ring with an alkali while controlling the pH; and the superabsorbent polymer thus obtained.

摘要翻译： 一种制备新的超吸收聚合物的方法，其通过在水溶液或有机溶剂中使聚琥珀酰亚胺与二胺反应以使部分交联聚琥珀酰亚胺，随后或同时用碱同时水解剩余的酰亚胺环，容易水解并符合环境，同时 控制pH值; 和由此获得的超吸收性聚合物。

公开(公告)号：US5424477A

公开(公告)日：1995-06-13

申请号：US128739

申请日：1993-09-30

申请人： Chojiro Higuchi ,  Ikumi Kitada ,  Akinori Nagatomo ,  Katashi Enomoto ,  Masanobu Ajioka ,  Akihiro Yamaguchi

发明人： Chojiro Higuchi ,  Ikumi Kitada ,  Akinori Nagatomo ,  Katashi Enomoto ,  Masanobu Ajioka ,  Akihiro Yamaguchi

IPC分类号： A23L27/30 ,  C07K5/075 ,  C07C209/06

CPC分类号： C07K5/0613

摘要： .alpha.-L-Aspartyl-L-phenylalanine methyl ester (.alpha.-APM) is prepared by catalytic hydrogenation of N-benzyloxycarbonyl-.alpha.-L-aspartyl-L-phenylalanine methyl ester (Z-.alpha.-APM). The catalytic hydrogenation is conducted in an aqueous suspension containing the Z-.alpha.-APM in the form of particles whose average particle size is not greater than 800 .mu.m. The starting Z-.alpha.-APM may contain up to 30 wt. % of its .beta.-isomer provided that the process additionally includes recrystallization of the .alpha.-APM, collection of the .alpha.-APM by filtration and recycling of the filtrate for use in the aqueous suspension of Z-.alpha.-APM.

摘要翻译： 通过N-苄氧羰基-α-L-天冬氨酰-L-苯丙氨酸甲酯（Z-α-APM）的催化氢化制备α-L-天冬氨酰-L-苯丙氨酸甲酯（α-APM）。 催化氢化在含有平均粒径不大于800μm的颗粒形式的Z-α-APM的水性悬浮液中进行。 起始的Z-α-APM可含有至多30wt。 ％的β-异构体，条件是该方法另外包括α-APM的重结晶，通过过滤收集α-APM并再循环用于Z-α-APM的水悬浮液中的滤液。

公开(公告)号：US5374765A

公开(公告)日：1994-12-20

申请号：US015931

申请日：1993-01-19

申请人： Tomoko Kamashita ,  Hiroyuki Yamashita ,  Teruyuki Nagata ,  Masanobu Ajioka

发明人： Tomoko Kamashita ,  Hiroyuki Yamashita ,  Teruyuki Nagata ,  Masanobu Ajioka

IPC分类号： C07C227/40 ,  C07C709/00

CPC分类号： C07C227/40

摘要： Disclosed is a method for extracting an amino acid ester from a hydrous solution which comprises adding thereto a water-insoluble organic solvent and then an amount of a base effective to liberate only a portion of the amino acid ester in free base form, and transferring the thus liberated amino acid ester in the free base form into the organic layer, and repeating the neutralization-extraction steps until all of the amino acid ester has been extracted.

摘要翻译： 公开了一种从含水溶液中提取氨基酸酯的方法，该方法包括向其中加入水不溶性有机溶剂，然后加入一定量的碱以有效释放一部分游离碱形式的氨基酸酯，并转移 从而将游离碱形式的氨基酸酯释放到有机层中，并重复中和提取步骤，直到所有的氨基酸酯被提取出来。

公开(公告)号：US5254323A

公开(公告)日：1993-10-19

申请号：US921606

申请日：1992-08-03

申请人： Hiroyuki Itoh ,  Yoshitsugu Kono ,  Isao Kikuchi ,  Shinji Takenaka ,  Masanobu Ajioka ,  Mitsuo Kudoh

发明人： Hiroyuki Itoh ,  Yoshitsugu Kono ,  Isao Kikuchi ,  Shinji Takenaka ,  Masanobu Ajioka ,  Mitsuo Kudoh

IPC分类号： C01B7/07 ,  C01B7/01 ,  B01D53/34

CPC分类号： C01B7/0743

摘要： A gaseous mixture containing chlorine, carbon dioxide and non-condensable gas is compressed and cooled to separate it into a residual gas formed principally of a major portion of the non-condensable gas and a condensate formed primarily of chlorine. The condensate is fed to a stripping column to desorb carbon dioxide and a minor portion of the non-condensable gas dissolved in the condensate. The stripped gas formed primarily of chlorine and carbon dioxide may be treated further. Namely, the stripped gas is mixed with the residual gas. At least a portion of the mixed gas is fed into an absorption column, whereby a major portion of remaining chlorine is absorbed to lower the chlorine content Removal of chlorine from such a gaseous mixture or an off-gas from the above process can be achieved by washing it with an aqueous solution or suspension containing an alkali metal sulfite and/or an alkaline earth metal sulfite while controlling the pH of the solution or suspension within a range of 1.9-6.3.

摘要翻译： 将含有氯，二氧化碳和不可冷凝气体的气体混合物压缩并冷却，将其分离成主要由不可冷凝气体主要形成的残留气体和主要由氯气形成的冷凝物。 将冷凝物供入汽提塔以解吸二氧化碳和少部分溶解在冷凝物中的不可冷凝气体。 主要由氯和二氧化碳形成的汽提气体可以进一步处理。 即，将汽提的气体与残留气体混合。 将混合气体的至少一部分进料到吸收塔中，从而吸收主要部分的剩余氯以降低氯含量从上述方法从这种气体混合物或废气中除去氯可以通过 用包含碱金属亚硫酸盐和/或碱土金属亚硫酸盐的水溶液或悬浮液洗涤，同时将溶液或悬浮液的pH控制在1.9-6.3的范围内。