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230 条记录 (耗时 0.026 秒)

    Method for microbially producing L-valine
    51.
    发明授权
    Method for microbially producing L-valine 失效
    微生物生产L-缬氨酸的方法

    公开(公告)号：US07632663B1

    公开(公告)日：2009-12-15

    申请号：US09914006

    申请日：2000-02-21

    申请人： Lothar Eggeling ,  Hermann Sahm

    发明人： Lothar Eggeling ,  Hermann Sahm

    IPC分类号： C12P13/04 ,  C12N9/02 ,  C12N9/04 ,  C12N9/10 ,  C12N9/88 ,  C12N15/00

    CPC分类号： C12N9/93 ,  C12N9/1014 ,  C12N9/88 ,  C12P13/06

    摘要： The present invention relates to a process for the microbial production of L-valine in which the dihydroxy acid-synthase (ilvD) activity and/or the ilvD gene expression is intensified in a microorganism. As an alternative or in combination with this, the acetohydroxy acid-synthase (ilvBN) activity and isomeroreductase (ilvC) activity and/or the ilvBNC gene expression are intensified in a microorganism. The process according to the invention preferably makes use of microorganisms in which the activity of at least one enzyme that is involved in a metabolic pathway that reduces the formation of L-valine is weakened or eliminated. Thus, for instance, the process according to the invention preferably makes use of microorganisms having a defect mutation in the threonine dehydratase (ilvA) gene and/or a defect mutation in one or more genes of the pantothenate synthesis.

    摘要翻译： 本发明涉及微生物生产L-缬氨酸的方法，其中二羟基酸合酶（ilvD）活性和/或ilvD基因表达在微生物中增强。 作为替代或与其结合，在微生物中增强乙酰羟酸合酶（ilvBN）活性和异构还原酶（ilvC）活性和/或ilvBNC基因表达。 根据本发明的方法优选利用其中减少或消除了减少L-缬氨酸形成的参与代谢途径的至少一种酶的活性的微生物。 因此，例如，根据本发明的方法优选利用在苏氨酸脱水酶（ilvA）基因中具有缺陷突变的微生物和/或泛酸合成的一种或多种基因中的缺陷突变。

    Method for the modeling of material and/or heat exchange process in a device and device for carrying out said method
    52.
    发明授权
    Method for the modeling of material and/or heat exchange process in a device and device for carrying out said method 失效
    用于实施所述方法的装置和装置中的材料和/或热交换过程建模的方法

    公开(公告)号：US07627460B2

    公开(公告)日：2009-12-01

    申请号：US10554437

    申请日：2004-04-15

    申请人： Dieter Froning ,  Andreas Gubner ,  Manfred Poppinger

    发明人： Dieter Froning ,  Andreas Gubner ,  Manfred Poppinger

    IPC分类号： G06G7/50 ,  H01M4/36 ,  H01M6/24

    CPC分类号： H01M8/04 ,  H01M8/0202 ,  H01M8/04074 ,  H01M8/24 ,  H01M8/2425 ,  H01M8/2483

    摘要： Mass transfer and/or heat transport processes in a fuel-cell stack are controlled by first modeling a selected region of the stack with at least two fluid components separated from one another by solid material. Each fluid component of the selected region is then transformed into a respective auxiliary volume in which all of the fluid components and solid material in the region are assembled additionally and whose outer cell corresponds to that of the region. Then each auxiliary volume is divided into a lattice with individual lattice elements that are linked by references so that linked or coupled lattices result. Finally the exchange between the fluids in the fuel-cell stack is implemented via the references of the respective component lattices.

    摘要翻译： 通过首先用固体材料彼此分离的至少两种流体组分对堆叠的选定区域进行建模来控制燃料电池堆中的质量传递和/或热传输过程。 然后将所选区域的每个流体组分转化成相应的辅助容积，其中该区域中的所有流体组分和固体材料被附加地组装，并且其外部单元对应于该区域的流体组分。 然后，每个辅助体积被分成具有通过引用链接的各个晶格元素的晶格，从而导致连接的或耦合的晶格。 最后，燃料电池堆中的流体之间的交换通过各个组件晶格的参考来实现。

    Method for producing a tensioned layer on a substrate, and a layer structure
    53.
    发明授权
    Method for producing a tensioned layer on a substrate, and a layer structure 失效
    在基板上制造张紧层的方法，以及层结构

    公开(公告)号：US07615471B2

    公开(公告)日：2009-11-10

    申请号：US10554074

    申请日：2004-04-08

    申请人： Siegfried Mantl

    发明人： Siegfried Mantl

    IPC分类号： H01L21/331

    CPC分类号： H01L21/76254 ,  H01L21/0245 ,  H01L21/02532 ,  H01L21/02664 ,  H01L29/7842 ,  Y10S438/938

    摘要： The invention relates to a method for producing a tensioned layer on a substrate involving the following steps: producing a defect area in a layer adjacent to the layer to be tensioned, and; relaxing at least one layer adjacent to the layer to be tensioned. Additional layers can be epitaxially deposited. Layer structures formed in this manner are advantageously suited for components of all types.

    摘要翻译： 本发明涉及一种在衬底上生产张紧层的方法，包括以下步骤：在邻近待张紧层的层中产生缺陷区域; 放松与要张紧的层相邻的至少一层。 另外的层可以外延沉积。 以这种方式形成的层结构有利地适用于所有类型的组件。

    Tomographic device and method with translational movement between object and detector
    56.
    发明授权
    Tomographic device and method with translational movement between object and detector 失效
    断层扫描仪与物体与探测器之间的平移运动

    公开(公告)号：US07498580B2

    公开(公告)日：2009-03-03

    申请号：US10576933

    申请日：2004-10-18

    申请人： Christian Lackas ,  Nils Schramm ,  Uwe Engeland

    发明人： Christian Lackas ,  Nils Schramm ,  Uwe Engeland

    IPC分类号： G01T1/166

    CPC分类号： G01T1/166 ,  A61B6/037 ,  G01T1/1642

    摘要： The invention relates to a device for carrying out a tomographic method, in particular for carrying out single-photon tomography, with at least one multi-hole collimator and at least one detector, for recording photons which pass through the multi-hole collimator. The above is characterised in comprising means which permit a relative translational movement between an object under investigation and the detector(s) with a positional accuracy of less than 1 millimeter. The relative positional change between object and detector(s) during the execution of the method is taken into account in the subsequent reconstruction method to an accuracy of less than 1 mm, in particular, less than 0.1 mm. A reconstruction method is used for the above which takes into account the positional and angular information between object and detector. Said method may be controlled by and carried out on a current PC.

    摘要翻译： 本发明涉及一种用于执行断层摄影方法的装置，特别是用于执行单光子层析成像，具有至少一个多孔准直器和至少一个检测器，用于记录通过多孔准直仪的光子。 上述特征在于包括允许正在研究的物体与检测器之间的相对平移运动的装置，位置精度小于1毫米。 在随后的重建方法中考虑到在执行该方法期间物体和检测器之间的相对位置变化小于1mm，特别是小于0.1mm的精度。 考虑到物体和检测器之间的位置和角度信息，上述的重建方法被使用。 所述方法可以由当前的PC控制和执行。

    Method for the hyperpolarisation of atomic nuclei and device for implementing the method
    57.
    发明授权
    Method for the hyperpolarisation of atomic nuclei and device for implementing the method 失效
    原子核超极化方法及其实现方法

    公开(公告)号：US07495435B2

    公开(公告)日：2009-02-24

    申请号：US10586000

    申请日：2005-01-13

    申请人： Stephan Appelt ,  Friedrich Wolfgang Häsing ,  Giovanni D'Orsaneo ,  Ulrich Sieling

    发明人： Stephan Appelt ,  Friedrich Wolfgang Häsing ,  Giovanni D'Orsaneo ,  Ulrich Sieling

    IPC分类号： G01V3/00

    CPC分类号： G01R33/282 ,  A61K49/1815

    摘要： An apparatus for hyperpolarizing atomic nuclei through optical pumping has a cylindrical optical pumping cell having an inlet and an outlet spaced therefrom. A supply of a mixture of optically pumpable species and hyperpolarizable nuclei is connected to the inlet of the cell. A nozzle at an inlet of the optical pumping cell forms and injects a jet flow of the mixture into the optical pumping cell. It is then drawn out through the outlet such that the mixture touches the inner walls of the optical pumping cell only adjacent the outlet.

    摘要翻译： 通过光泵浦使原子核超极化的装置具有圆柱形的光泵浦单元，其具有与其间隔开的入口和出口。 供应光泵浦物质和超极化核的混合物连接到电池入口。 在光泵浦单元的入口处的喷嘴形成并将混合物的喷射流注入到光泵浦单元中。 然后通过出口将其抽出，使得混合物仅在出口附近接触光泵浦单元的内壁。

    System for measuring burn-out of fuel elements of a high-temperature reactor
    59.
    发明授权
    System for measuring burn-out of fuel elements of a high-temperature reactor 失效
    测量高温反应堆燃料元件燃耗的系统

    公开(公告)号：US07349517B2

    公开(公告)日：2008-03-25

    申请号：US10546086

    申请日：2004-01-15

    申请人： Peter Pohl

    发明人： Peter Pohl

    IPC分类号： G21C17/00

    CPC分类号： G21C1/07 ,  G21C17/066 ,  G21Y2002/202 ,  G21Y2002/204 ,  G21Y2004/40 ,  Y02E30/36

    摘要： The burnout of a fuel element in a reactor is determined by first transferring a fuel element from a reactor to a measuring position and then subjecting the transferred fuel element at the position to a neutron flux. A first detector measures the total γ radiation emitted by the transferred fuel element and thereafter, if the radiation measured by the first detector exceeds a predetermined first limit, the transferred fuel element is returned back to the reactor. If not, a second detector measures a magnitude of high energy γ radiation above 1 MeV emitted by the transferred fuel element and thereafter only if the radiation measured by the second detector exceeds a predetermined second limit, the transferred fuel element is transferred back to the reactor. The element is not returned to the reactor if the radiation measured by the second detector is below the second limit.

    摘要翻译： 燃料元件在反应器中的燃烧是通过首先将燃料元件从反应器传送到测量位置，然后使转移的燃料元件在该位置经受中子通量来确定的。 第一检测器测量由传送的燃料元件发射的总伽马辐射，此后，如果由第一检测器测量的辐射超过预定的第一极限，则转移的燃料元件返回到反应器。 如果不是，第二检测器测量由转移的燃料元件发射的高于1MeV的高能伽马辐射的大小，此后仅当由第二检测器测量的辐射超过预定的第二限度时，转移的燃料元件被传回到反应器 。 如果由第二检测器测量的辐射低于第二限度，则元件不会返回到电抗器。