Process for the production of esterquats
    56.
    发明申请
    Process for the production of esterquats 审中-公开
    生产酯季铵盐的工艺

    公开(公告)号:US20020002298A1

    公开(公告)日:2002-01-03

    申请号:US09854106

    申请日:2001-05-11

    IPC分类号: C07C229/06 C11D001/38

    摘要: The invention relates to a process for the production of esterquats in which triglycerides are transesterified with alkanolamines and the resulting fatty acid alkanolamine esters are subsequently quaternized with alkyl halides or dialkyl sulfates in the presence of solvents, characterized in that glycerol released during the transesterification is continuously removed from the reaction equilibrium.

    摘要翻译: 本发明涉及一种生产酯季铵盐的方法,其中甘油三酸酯与链烷醇胺进行酯交换,随后在溶剂存在下,将所得脂肪酸链烷醇胺酯与烷基卤化物或二烷基硫酸盐季铵化,其特征在于酯交换期间释放的甘油连续 从反应平衡中除去。

    High blood pressure relief method and compositions
    57.
    发明授权
    High blood pressure relief method and compositions 失效
    高血压缓解方法和组合物

    公开(公告)号:US5708029A

    公开(公告)日:1998-01-13

    申请号:US559758

    申请日:1995-11-13

    申请人: Arthur Vanmoor

    发明人: Arthur Vanmoor

    CPC分类号: A61K31/198 A61K31/197

    摘要: Disclosed is the method of determining the effectiveness of an agent for the relief of elevation of the blood pressure, comprising the steps of a) administering to a susceptible subject a quantity of a trigger substance reproducibly effective in producing within a period of six hours a perceptible increase in blood pressure lasting for at least twenty-four hours in the absence of treatment, b) administering to said subject having received said quantity of trigger substance a predetermined quantity of the agent whose effectiveness is to be determined, c) measuring the duration of said elevation of blood pressure upon administering said agent, and d) comparing the duration of said elevation with and without the administration of said agent. Also disclosed are effective quantities of certain nutrient substances which can reproducibly relieve elevated blood pressure produced in a susceptible subject by the administration of a trigger substance.

    摘要翻译: 公开了确定用于缓解血压升高的药剂的有效性的方法,包括以下步骤:a)向易感患者施用一定量的可触发性物质,其在六小时内可重现地产生有效的可察觉的 在没有治疗的情况下,持续至少24小时的血压升高,b)对接受所述量的触发物质的所述受试者施用预定量的有效性的确定剂,c)测量持续时间 所述药剂的给药时升高血压,和d)比较所述药物的施用时间和给药时间。 还公开了通过施用触发物质可以可重复地缓解易感受试者产生的升高的血压的某些营养物质的有效量。

    Carboxylate protective groups, a process for their preparation, their
coupling to a functional group, and their use
    59.
    发明授权
    Carboxylate protective groups, a process for their preparation, their coupling to a functional group, and their use 失效
    羧酸酯保护基团,其制备方法,与官能团的偶联及其用途

    公开(公告)号:US5639859A

    公开(公告)日:1997-06-17

    申请号:US440836

    申请日:1995-05-15

    摘要: Carboxylate protective groups, a process for their preparation, their coupling to a funcitonal group, and their useCarboxylates of polar, hydrophilic alcohols of the formula ##STR1## in which R is an unbranched or branched organic radical which contains, as polar members between aliphatic or araliphatic hydrocarbon bridges, ether oxygens, amine nitrogen groups or a mixture of ether and amine groups which can be incorporated into a cyclic structure, where the total length does not exceed 20 members and where, in the case of polyethylene glycol [(CH.sub.2 --CH.sub.2 --O).sub.n ], n indicates the number of the members and is defined as any integer, andR' is an aliphatic or araliphatic radical which has at least one functional group,are suitable as protective groups since they can be introduced selectively into functional groups of organic compounds and eliminated specifically by lipases.

    摘要翻译: 羧酸酯保护基团,它们的制备方法,它们与功能基团的偶联,以及它们的用途式为“IMAGE”的极性亲水醇的羧酸盐,其中R是无支链或支链的有机基团,其含有作为脂族 或芳族烃桥,醚氧基,胺氮基团或可结合到环状结构中的醚和胺基团的混合物,其中总长度不超过20个成员,其中在聚乙二醇[(CH 2 - CH2-O)n],n表示成员数,定义为任何整数,R'是具有至少一个官能团的脂族或芳脂族基,适合作为保护基,因为它们可以选择性地引入 有机化合物的官能团,并由脂肪酶特异性消除。