公开(公告)号：US12065509B2

公开(公告)日：2024-08-20

申请号：US17520141

申请日：2021-11-05

申请人： HD IMMUNE GMBH

发明人： Oskar Smrzka ,  Stefan Bartl ,  Michela Parth

IPC分类号： C07K17/02 ,  C07K16/18 ,  G01N33/577 ,  G01N33/68

CPC分类号： C07K17/02 ,  C07K16/18 ,  G01N33/577 ,  G01N33/6896 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/565 ,  G01N2800/2835

摘要： A monoclonal antibody may have a binding domain that binds to a peptide of the HTT protein having the sequence of p7543 (SEQ ID No. 3). Such a monoclonal according may include a heavy chain variable region CDR1 comprising GYTFTEYT (SEQ ID No. 66), a heavy chain variable region CDR2 comprising INPNNGGT (SEQ ID No. 67), a heavy chain variable region CDR3 comprising ASLDGRDY (SEQ ID No. 68), a light chain variable region CDR1 comprising QSLLNSRTRKNY (SEQ ID No. 69), a light chain variable region CDR2 comprising WAS (SEQ ID No. 70), and/or a light chain variable region comprising KQSYNLLT (SEQ ID No. 71).

公开(公告)号：US12059279B2

公开(公告)日：2024-08-13

申请号：US18362434

申请日：2023-07-31

申请人： Hologic, Inc.

发明人： Kenneth F. Defreitas ,  Alan Rego ,  Richard Gladwin Edwards ,  Zhenxue Jing ,  Jay A. Stein ,  Timothy N. Wells ,  Cornell Lee Williams

IPC分类号： A61B6/04 ,  A61B6/50 ,  A61B6/02 ,  A61B6/03

CPC分类号： A61B6/0414 ,  A61B6/0435 ,  A61B6/502 ,  A61B6/025 ,  A61B6/032

摘要： While performing a tomosynthesis procedure, the breast of a patient is compressed between two compression elements to create an imaging condition. Foam is secured to the rigid substrate of a one of the compression elements. The patient's chest wall is aligned with the leading edge surface of the foam. The inner side of the breast is disposed proximate the lateral edge surface of the foam and the outer side of the breast is disposed proximate the outer lateral edge surface of the foam. A mid-plane is disposed between the inner and outer lateral edge surfaces of the foam. An interface connects a leading edge surface of the foam and compressive surfaces. A portion of the leading edge surface which is aligned with the mid-plane is incompletely compressed.

公开(公告)号：US12059226B2

公开(公告)日：2024-08-13

申请号：US17056375

申请日：2019-05-17

申请人： MEDICAL MICROINSTRUMENTS, INC.

发明人： Massimiliano Simi ,  Giuseppe Maria Prisco

IPC分类号： A61B34/00 ,  A61B34/37 ,  A61B17/00 ,  A61B50/30 ,  A61B90/60

CPC分类号： A61B34/74 ,  A61B34/37 ,  A61B2017/00221 ,  A61B2017/00862 ,  A61B2050/314 ,  A61B90/60

摘要： A master controller assembly for a robotic surgery system has a slave robot assembly having a slave surgical grip device providing a grip degree-of-freedom of motion lying in a predefined slave grip plane and a control unit. The master controller assembly has a portable hand-held master input tool operatively connected to the slave robot assembly. The master input tool has a master tool body having a manipulandum surface, to be hand-held by the surgeon's fingers. The master input tool is mechanically unconstrained from the slave robot assembly and has a grip command detector device having an operative portion. The operative portion is manually operable by radially directed pressure action exerted at an operative surface. A sensing assembly detects the radially directed pressure action so that the radially directed pressure action exerted at the operative surface determines a paired slave grip motion action of the surgical slave grip device.

公开(公告)号：US12059141B2

公开(公告)日：2024-08-13

申请号：US17549432

申请日：2021-12-13

申请人： Critical Innovations, LLC

发明人： Ross I. Donaldson ,  Timothy Fisher ,  Oliver Buchanan ,  Jon Armstrong ,  John Cambridge

IPC分类号： A61B17/00 ,  A61L24/00 ,  A61L24/04

CPC分类号： A61B17/0057 ,  A61L24/0026 ,  A61L24/0042 ,  A61L24/046 ,  A61B2017/00495 ,  A61B2017/00522 ,  A61B2017/00778 ,  A61B2017/00818 ,  A61B2017/00884 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61L2300/404 ,  A61L2300/418 ,  A61L2430/36

摘要： Systems, methods and compositions relating to delivering synthetic polymer formulations to the body are described, which can be used by a range of medical personnel including those with minimal experience and training. Under some embodiments, the present invention relates to systems and devices for delivering polymer formulations to a body cavity (e.g. peritoneal cavity) to reduce or stop bleeding. Under some embodiments, an initial percutaneous access pathway is first formed using a delivery device with a probe and needle mechanism that automatically stops the advance of the device upon insertion into a body cavity or space, thus minimizing user error and improving patient safety. The hollow probe then allows transmission of polymer, mixed with gas and/or additional substances, from a holding chamber or canister to flow through the device and hollow probe into the patient's anatomic cavity or space of interest, stopping expansion when the device senses the appropriate pressure. Once reaching the body cavity, the polymer formulation functions to reduce and/or stop bleeding.

公开(公告)号：USD1038329S1

公开(公告)日：2024-08-06

申请号：US29854947

申请日：2022-09-29

申请人： ASSA ABLOY Americas Residential Inc.

设计人： Cameron Lee Potter ,  Tony Zhang

摘要： FIG. 1 is a top perspective view of an exemplary faucet according to a new design;
FIG. 2 is a left side view thereof;
FIG. 3 is a right side view thereof;
FIG. 4 is a front view thereof;
FIG. 5 is a back view thereof;
FIG. 6 is a top view thereof;
FIG. 7 is a bottom view thereof; and,
FIG. 8 is a bottom perspective view thereof.
The portions depicted in broken lines form no part of the claimed design.

公开(公告)号：US12056669B2

公开(公告)日：2024-08-06

申请号：US17434532

申请日：2020-02-26

申请人： Eaton Intelligent Power Limited

发明人： Karthikeyan S. Chokappa ,  Samuel B. Lazarus ,  Steve D. Townes, Jr. ,  Sukhbir Kashyap ,  Galen L. Chui ,  Aniruddh S. Deshpande ,  Anil B. Ghegade ,  Mijaz Mukundan ,  Andrew M. Laskovy

IPC分类号： G06V10/00 ,  G06Q10/20 ,  G06T7/00

CPC分类号： G06Q10/20 ,  G06T7/0006

摘要： A maintenance method for servicing a component includes generating, via an electronic control unit, a digital model of the component, detecting, via the electronic control unit, a defect of the component, classifying, via the electronic control unit, the defect as a defect type, and evaluating the defect to determine, according to the defect type, whether to repair the defect or to replace a section of the component containing the defect. A maintenance system for servicing components may include a scanner and an ECU configured to create a digital model of a component, detect a defect of the component from the digital model and/or three-dimensional data of the component, classify the defect as a defect type of a plurality of defect types, and/or evaluate the defect according to the defect type.

公开(公告)号：US12055887B2

公开(公告)日：2024-08-06

申请号：US18327204

申请日：2023-06-01

申请人： BROTHER KOGYO KABUSHIKI KAISHA

发明人： Yasumasa Fujii ,  Shougo Sato

IPC分类号： G03G15/00 ,  G03G15/08 ,  G03G21/16 ,  G03G21/18

CPC分类号： G03G21/1842 ,  G03G15/0867 ,  G03G21/1619 ,  G03G21/1647 ,  G03G21/1676

摘要： An image forming apparatus includes a main body housing, a drawer, and a toner cartridge. The main body housing includes a first wall arranged at a first direction side of the main body housing and having a first opening, a second wall arranged at a second direction side perpendicular to the first direction and having a second opening, a first door at the first opening, and a second door at the second opening. The drawer supports a drum cartridge having a photosensitive drum. When the first door is opened, the drawer is movable between an inner position where the drawer is located inside the main body housing and an outer position where the drawer is located outside the main body housing. When the second door is opened, the toner cartridge is detachable from and is attachable to the main body housing through the second opening in the second direction.

公开(公告)号：US12055781B2

公开(公告)日：2024-08-06

申请号：US18458301

申请日：2023-08-30

申请人： CommScope Connectivity Belgium BVBA

发明人： Johan Geens ,  Pieter Vermeulen ,  Eric Marcel M. Keustermans

IPC分类号： G02B6/44 ,  G02B6/255 ,  G02B6/26 ,  G02B6/36

CPC分类号： G02B6/4455 ,  G02B6/2553 ,  G02B6/262 ,  G02B6/3616

摘要： A mounting system (700/900) for locking two pieces of telecommunications equipment (610/810) to prevent relative sliding therebetween and relative separation therebetween in a direction generally perpendicular to the direction of the relative sliding includes a first locking feature (701/901) defined by a stud (702/902) with a stem portion (708/908) and a flange portion (710/910) having a larger profile than the stem portion (708/908) and a second locking feature (703/903) defined by a slot (704/904) with a receiver portion (712/912) and a retention portion (714/914). The receiver portion (712/912) is sized to accommodate the flange portion (710/910) of the stud (702/902) and the retention portion (714/914) is sized to accommodate the stem portion (708/908) but not the flange portion (710/910) of the stud (702/902). A third locking feature (705/905) prevents relative sliding between the two pieces of telecommunications equipment (610/810) once the stud stem portion (708/908) has been slid within the slot retention portion (714/914) and the stud flange portion (710/910) is out of alignment with the slot receiver portion (712/912).

公开(公告)号：US12055166B2

公开(公告)日：2024-08-06

申请号：US17574050

申请日：2022-01-12

申请人： DANFOSS A/S

发明人： Aaron Hertzel Jagoda ,  Eric Joseph Mann

IPC分类号： F16H3/44 ,  E02F9/22 ,  F15B11/16 ,  F15B21/08 ,  F16H3/72 ,  H02K7/108 ,  H02K7/116 ,  H02K11/00 ,  F16H47/04

CPC分类号： F15B21/087 ,  E02F9/2271 ,  E02F9/2289 ,  F15B11/165 ,  F16H3/44 ,  F16H3/724 ,  H02K7/108 ,  H02K7/116 ,  H02K11/0094 ,  F16H47/04 ,  F16H2200/2005

摘要： A variator includes an epicyclic gear set that has at least three nodes. The variator includes a pumping unit connected to a first node of the epicyclic gear set. The variator includes a clutch connected to a second node of the epicyclic gear set. The clutch is selectively movable between three positions. When in the first position, the clutch allows the second node to freewheel. When in the second position, the clutch connects the second node to a fixed surface. When in the third position, the clutch connects the second node to an electric motor. The variator includes a receiver connected to the third node of the epicyclical gear set. The receiver is configured to receive a drive shaft.

公开(公告)号：US12054148B2

公开(公告)日：2024-08-06

申请号：US17167811

申请日：2021-02-04

申请人： PACCAR INC

发明人： Josef Lotz ,  Nathan Paul ,  Tristan Pyle ,  Bryan Ross

IPC分类号： B60W30/14 ,  B60K31/16 ,  B60W50/14 ,  B60K31/00

CPC分类号： B60W30/146 ,  B60K31/16 ,  B60W50/14 ,  B60K2031/0091 ,  B60K2310/00 ,  B60W2510/30 ,  B60W2555/20

摘要： A cruise control interlock system detects a current set of conditions for a vehicle, compares the current conditions with cruise control interlock conditions (e.g., an adjustable threshold state of a windshield wiper system), and executes a process to deactivate the cruise control system. The process to deactivate functionality of the cruise control system may include presenting a notification to the operator to alert the operator to an upcoming automatic deactivation or to encourage the operator to deactivate cruise control. The process also may include a vehicle de-rate process (e.g., reducing vehicle speed) to induce the operator to deactivate cruise control. Deactivation of cruise control may be postponed in some situations, such as when the vehicle is ascending an uphill grade or where doing so may deactivate an active downhill speed control function.