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119 条记录 (耗时 0.058 秒)

    System for manufacturing a circular primary surface recuperator
    61.
    发明授权
    System for manufacturing a circular primary surface recuperator 有权
    圆形主面换热器制造系统

    公开(公告)号：US06687979B2

    公开(公告)日：2004-02-10

    申请号：US10012860

    申请日：2001-11-30

    申请人： Charles W. Bucey ,  Robert M. Jones ,  Steven W. Clayton ,  Chad L. Miars ,  Douglas R. Ervin

    发明人： Charles W. Bucey ,  Robert M. Jones ,  Steven W. Clayton ,  Chad L. Miars ,  Douglas R. Ervin

    IPC分类号： B23P1526

    CPC分类号： B23P15/26 ,  B23P19/04 ,  F28D9/0018 ,  Y10T29/49357 ,  Y10T29/5188 ,  Y10T29/53113 ,  Y10T29/53122 ,  Y10T29/53539

    摘要： A system is disclosed to manufacture a recuperator core. The core is made up of a plurality of cells and an inner sealing member. A manufacturing system has an input end, an assembly station having a lower or inner chucking portion and an upper portion, and a welding station. The lower or inner chucking portion is movable between a lower position and an upper position and has a retracted position and an expanded position. The upper portion is movable between a loading position and a clamping position and is rotatable between a first position and a second position. The welding station performs a tack welding operation and a lineal welding operation.

    摘要翻译： 公开了一种用于制造换热器铁心的系统。 芯由多个电池和内密封件构成。 制造系统具有输入端，具有下部或内部夹持部分和上部的组装站以及焊接站。 下部或内部夹持部分可在下部位置和上部位置之间移动并且具有缩回位置和展开位置。 上部可在装载位置和夹紧位置之间移动，并可在第一位置和第二位置之间转动。 焊接站进行定位焊接操作和直线焊接操作。

    Method and apparatus for automatically determining the approval status of a potential borrower
    63.
    发明授权
    Method and apparatus for automatically determining the approval status of a potential borrower 失效

    公开(公告)号：US5239462A

    公开(公告)日：1993-08-24

    申请号：US841397

    申请日：1992-02-25

    申请人： Robert M. Jones ,  Charles F. Goetz ,  Larry L. Steele

    发明人： Robert M. Jones ,  Charles F. Goetz ,  Larry L. Steele

    IPC分类号： G06F17/24 ,  G06Q20/40 ,  G07F7/08

    CPC分类号： G07F7/08 ,  G06F17/243 ,  G06Q20/4037 ,  G06Q40/02 ,  G06Q40/025

    摘要： A method and apparatus are provided for the real-time automatic determination of the approval status of a potential borrower of a loan. The method includes (1) transmitting an image of a form by facsimile transmission to a control location, wherein the form contains predefined information applicable to the potential borrower in spaces located at predetermined locations; (2) automatically receiving the image of the form by facsimile transmission at the control location; (3) automatically scanning and interpreting the image of the form to obtain the predefined information; (4) automatically determining at the control location the approval status of the potential borrower according to criteria provided by a lender, wherein the determining step utilizes the predefined information; and (6) automatically transmitting information regarding the approval status from the control location to the potential borrower. The invention further provides for a method and apparatus for scanning and interpreting a coded form received by facsimile transmission such that the form comprises a sheet having a predetermined number of timing marks spaced at predetermined intervals along the right hand and left hand vertical borders of the sheet such that each timing mark along the left hand border is paired with one timing mark along the right hand border. This method includes (1) automatically scanning the form to ascertain the presence and location of the predetermined number of timing marks; (2) automatically locating the vertical center of each timing mark; (3) automatically locating a line between the vertical center of each left hand timing mark to the vertical center of the respective paired right hand timing mark; (4) automatically detecting the spaces in predetermined locations along each line; and (5) automatically obtaining the predefined information applicable to the potential borrower from the spaces.

    In-line, continuous paper batching system
    64.
    发明授权
    In-line, continuous paper batching system 失效
    连续式连续造纸系统

    公开(公告)号：US5014974A

    公开(公告)日：1991-05-14

    申请号：US464970

    申请日：1990-01-16

    申请人： Donald A. Jones ,  Robert M. Jones

    发明人： Donald A. Jones ,  Robert M. Jones

    IPC分类号： B65H31/32

    CPC分类号： B65H31/32 ,  B65H29/66

    摘要： An apparatus for in-line, high-speed stacking of paper signatures which includes two or more horizontally disposed batch forks having integral, pivoting fingers which project upstream towards an incoming flow of shingles being continuously conveyed from a sheeter. The batch forks are supported on a paper batching carriage, and can be raised and lowered from a pivot point, and retracted to transfer a partial stack of shingles to intermediate interrupt forks or to main pile forks for transfer to a conveyor. These additional paper handling forks cooperate with the batch forks and integral, pivoting fingers to continuously stack the shingled sheets in quantities determined by a counting and control system. The pivoting fingers depress the incoming signatures to separate them into stacks without slowing flow from a present rate of about 1200-1300 f.p.m. and higher.

    摘要翻译： 一种用于在线高速堆叠纸张签名的设备，其包括两个或更多个水平布置的批量叉，其具有整体的，枢转的指状物，其向上游朝向从片材机连续传送的进入的木瓦流。 批料叉被支撑在纸批量托架上，并且可以从枢轴点升高和降低，并且缩回以将部分瓦片板传递到中间中断叉或主桩叉以传送到输送机。 这些附加的纸张处理叉与批叉和一体的，枢转的手指配合，以由计数和控制系统确定的量连续堆叠带状片。 枢转的手指按压输入的签名以将它们分成堆叠，而不会从约1200-1300f.p.m的当前速率减慢流量。 和更高。

    Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
    67.
    发明申请
    Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto 审中-公开
    GPR119受体的调节剂和与之相关的疾病的治疗

    公开(公告)号：US20140038889A1

    公开(公告)日：2014-02-06

    申请号：US14113085

    申请日：2012-04-20

    申请人： Robert M. Jones

    发明人： Robert M. Jones

    IPC分类号： C07D401/14 ,  A61K45/06 ,  A61K31/506

    CPC分类号： C07D401/14 ,  A61K31/506 ,  A61K45/06

    摘要： The present invention relates to the GPR119 agonist, 1-methylcyclopropyl 4-(5-fluoro-6-(2-methyl-6-(methylsulfonyl)pyridin-3-yloxy)pyrimidin-4-yloxy)piperidine-1-carboxylate (Compound 1): and pharmaceutically acceptable salts, solvates, and hydrates thereof, that are useful as single pharmaceutical agents or in combination with one or more additional pharmaceutical agents, such as, a DPP-IV inhibitor, a biguanide, an alpha-glucosidase inhibitor, an insulin analogue, a sulfonylurea, an SGLT2 inhibitor, a meglitinide, a thiazolidinedione, or an anti-diabetic peptide analogue, in the treatment of for example, a disorder selected from: a GPR119-receptor-related disorder; a condition ameliorated by increasing the secretion of an incretin; a condition ameliorated by increasing a blood incretin level; a condition characterized by low bone mass; a neurological disorder; a metabolic-related disorder; type 2 diabetes; obesity; and complications related thereto.

    摘要翻译： 本发明涉及GPR119激动剂，4-（5-氟-6-（2-甲基-6-（甲基磺酰基）吡啶-3-基氧基）嘧啶-4-基氧基）哌啶-1-甲酸1-甲基环丙酯（化合物 1）及其药学上可接受的盐，溶剂合物和水合物，其可用作单一药剂或与一种或多种另外的药剂如DPP-IV抑制剂，双胍类，α-葡糖苷酶抑制剂， 胰岛素类似物，磺酰脲类，SGLT2抑制剂，兆奈德，噻唑烷二酮或抗糖尿病肽类似物，用于治疗例如选自以下的病症：GPR119-受体相关病症; 通过增加肠降血糖素的分泌而改善的状况; 通过增加血液肠降血糖水平来改善病情; 以低骨量为特征的病症; 神经障碍 代谢相关疾病; 2型糖尿病; 肥胖; 和相关的并发症。

    Methods of using a G protein-coupled receptor to identify peptide YY (PYY) secretagogues
    69.
    发明授权
    Methods of using a G protein-coupled receptor to identify peptide YY (PYY) secretagogues 失效
    使用G蛋白偶联受体鉴定肽YY（PYY）促分泌素的方法

    公开(公告)号：US08486646B2

    公开(公告)日：2013-07-16

    申请号：US12765406

    申请日：2010-04-22

    申请人： Zhi-Liang Chu ,  James N. Leonard ,  Robert M. Jones

    发明人： Zhi-Liang Chu ,  James N. Leonard ,  Robert M. Jones

    IPC分类号： G01N33/53 ,  G01N33/567 ,  C12P21/06 ,  C12N1/20 ,  C12N15/00 ,  C12N5/00 ,  C12N5/02 ,  C12N15/74

    CPC分类号： G01N33/68 ,  G01N33/5044 ,  G01N2333/726 ,  G01N2800/042 ,  G01N2800/044 ,  G01N2800/065 ,  G01N2800/108 ,  G01N2800/323

    摘要： The present invention relates to methods of using GPR119 receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY, such as conditions modulated by stimulation of NPY Y2 receptor (Y2R). Agonists of GPR119 receptor are useful as therapeutic agents for treating or preventing a condition modulated by PYY, such as a condition modulated by stimulation of Y2R. Conditions modulated by PYY such as may be a condition modulated by stimulation of Y2R include bone-related conditions, metabolic disorders, angiogenesis-related conditions, ischemia-related conditions, convulsive disorders, malabsorptive disorders, cancers, and inflammatory disorders.

    摘要翻译： 本发明涉及使用GPR119受体鉴定肽YY（PYY）促分泌素和可用于治疗由PYY调节的病症的化合物的方法，例如通过刺激NPY Y2受体（Y2R）调节的病症。 GPR119受体的激动剂可用作治疗或预防由PYY调节的病症的治疗剂，例如通过刺激Y2R调节的病症。 由PYY调节的病症例如可能是通过Y2R刺激调节的病症包括骨相关病症，代谢紊乱，血管生成相关病症，缺血相关病症，惊厥症，吸收不良障碍，癌症和炎症性疾病。