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70 条记录 (耗时 0.033 秒)

    Method for modulating, regulating and/or stabilizing angiogenesis
    63.
    发明申请
    Method for modulating, regulating and/or stabilizing angiogenesis 失效
    调节，调节和/或稳定血管发生的方法

    公开(公告)号：US20050260161A1

    公开(公告)日：2005-11-24

    申请号：US11073605

    申请日：2005-03-08

    申请人： Karl Alitalo ,  Ulf Eriksson ,  Marko Uutela

    发明人： Karl Alitalo ,  Ulf Eriksson ,  Marko Uutela

    IPC分类号： A61K38/18 ,  A61K48/00

    CPC分类号： A61K38/1858 ,  A61K48/00

    摘要： A method of modulating, regulating and/or stabilizing angiogenesis in a mammal in need thereof, in which the PDGF-D level or activity or both in the mammal are modulated or increased. In preferred embodiments, an active PDGF-D polypeptide, or a polynucleotide encoding an active PDGF-D is administered to the mammal, preferably at a location where angiogenesis modulation or stabilization is desired. The PDGF-D is advantageously co-administered with an angiogenic growth factor, such as a member of the VEGF family of growth factors, in particular VEGF-E. The claimed method inhibits leakage of blood vessels and is useful, inter alia, for treatment of edemas.

    摘要翻译： 在有需要的哺乳动物中调节，调节和/或稳定血管发生的方法，其中调节或增加哺乳动物的PDGF-D水平或活性。 在优选的实施方案中，将活性PDGF-D多肽或编码活性PDGF-D的多核苷酸施用于哺乳动物，优选在需要血管生成调节或稳定的位置。 PDGF-D有利地与血管生成生长因子如生长因子VEGF家族的成员，特别是VEGF-E共同施用。 所要求保护的方法抑制血管渗漏，尤其用于治疗水肿。

    Methods for detecting for the presence of tumor cells and for screening for anti-tumor agents
    64.
    发明申请
    Methods for detecting for the presence of tumor cells and for screening for anti-tumor agents 审中-公开
    用于检测肿瘤细胞的存在和用于筛选抗肿瘤剂的方法

    公开(公告)号：US20050250103A1

    公开(公告)日：2005-11-10

    申请号：US10705944

    申请日：2003-11-13

    申请人： Xuri Li ,  Karin Aase ,  Ulf Eriksson

    发明人： Xuri Li ,  Karin Aase ,  Ulf Eriksson

    IPC分类号： G01N33/50 ,  C12Q1/68 ,  C12Q1/6886 ,  G01N33/15 ,  G01N33/574

    CPC分类号： G01N33/57484 ,  C12Q1/6886 ,  C12Q2600/136 ,  G01N2333/49

    摘要： A method and kit for detecting the presence of tumor cells in an animal by detecting expression of VEGF-B186, determining an increased expression of VEGF-B186, or by determining an increased expression of VEGF-B186 relative to expression of VEGF-B167. The kit comprises a receptacle adapted to receive a sample and a means for detecting expression of VEGF-B186 from the sample. Also, a method for screening for anti-tumor agents.

    摘要翻译： 用于通过检测VEGF-B 186的表达，确定VEGF-B 186的表达增加或通过确定VEGF-B 186的表达来检测动物中肿瘤细胞的存在的方法和试剂盒 相对于VEGF-B 167的表达增加VEGF-B 186的表达。 试剂盒包括适于接收样品的容器和用于从样品中检测VEGF-B 186的表达的装置。 另外，用于筛选抗肿瘤剂的方法。

    Method for downlink attenuation based on mobile protocol version
    66.
    发明授权
    Method for downlink attenuation based on mobile protocol version 有权
    基于移动协议版本的下行链路衰减方法

    公开(公告)号：US06836473B1

    公开(公告)日：2004-12-28

    申请号：US09625361

    申请日：2000-07-25

    申请人： Ulf Eriksson

    发明人： Ulf Eriksson

    IPC分类号： H04B7212

    CPC分类号： H04W72/048

    摘要： In a TDMA (Time Division Multiple Access) wireless communication system, mobile stations are sorted according to their PV (Protocol Version), and packed by an enhanced FRP (Frequency Re-Packing) function or an enhanced IDCS (Interference Driven Channel Selection) function so mixing of mobile stations with different PVs on the same carrier will be avoided as far as possible. This allows mobile station capabilities to be used with greater advantage, in situations where a protocol or other performance feature used on a carrier must be compatible with the least capable mobile station on the carrier. In a broader sense, the mobile stations can be sorted and then allocated based on any appropriate indicator of mobile station capability, for example PV, mobile station ESN (Electronic Serial Number), and so forth. In this way, a common capability of all mobiles on the same carrier, can be maximized for some or all carriers within a cell. Thus, an overall efficiency or performance level of the mobile system can be enhanced or maximized.

    摘要翻译： 在TDMA（时分多址）无线通信系统中，根据其PV（协议版本）对移动台进行分类，并通过增强的FRP（频率重新包装）功能或增强的IDCS（干扰驱动信道选择）功能进行打包 因此，尽可能避免移动台与同一载波上的不同PV的混合。 这样，在载波上使用的协议或其他性能特征必须与运营商上能力最差的移动台兼容的情况下，可以更有效地使用移动台能力。 在更广泛的意义上，可以基于移动台能力的任何适当的指示符，例如PV，移动台ESN（电子序列号）等来分类和分配移动台。 以这种方式，可以使单元中的一些或所有载波的同一载波上的所有移动台的共同能力最大化。 因此，可以提高或最大化移动系统的整体效率或性能水平。

    Support plate for tube heat exchangers and a tube heat exchanger
    67.
    发明授权
    Support plate for tube heat exchangers and a tube heat exchanger 失效
    管式热交换器支架和管式换热器

    公开(公告)号：US06334483B1

    公开(公告)日：2002-01-01

    申请号：US09284440

    申请日：1999-07-14

    申请人： Göran Berglund ,  Ulf Eriksson

    发明人： Göran Berglund ,  Ulf Eriksson

    IPC分类号： F28F1900

    CPC分类号： F28F21/082 ,  C01P2004/62 ,  C09C1/50 ,  C22C38/50 ,  F28F9/0229 ,  F28F19/002 ,  F28F19/06

    摘要： A tube heat exchanger for the production of carbon black includes a support plate located at the lower end of a space through which heat exchanger tubes extend. The plate includes upper and lower spar support plates forming a spar space therebetween through which the heat exchanger tubes extend. The spar space is divided into a plurality of canals by partition walls. Each canal has its own inlet and outlet for conducting a flow of cooling medium. The flow direction of cooling medium in each canal is opposite that of an adjacent canal. Portions of the support plate are formed of an aluminum-containing, iron-based alloy produced powder-metallurgically.

    摘要翻译： 用于生产炭黑的管式热交换器包括位于热交换器管延伸的空间下端的支撑板。 板包括上和下翼梁支撑板，其在其间形成翼梁空间，热交换器管通过该翼梁间隔延伸。 翼梁空间通过分隔壁分成多个运河。 每个管道都有自己的入口和出口，用于进行冷却介质的流动。 每个管道中冷却介质的流动方向与相邻管道的流动方向相反。 支撑板的一部分由冶金制成的含铝铁基合金形成。

    Antibodies specific for vascular endothelial growth factor-B
    68.
    发明授权
    Antibodies specific for vascular endothelial growth factor-B 失效
    血管内皮生长因子B特异性抗体

    公开(公告)号：US06331301B1

    公开(公告)日：2001-12-18

    申请号：US08851896

    申请日：1997-05-06

    申请人： Ulf Eriksson ,  Birgitta Olofsson ,  Kari Alitalo ,  Katri Pajusola

    发明人： Ulf Eriksson ,  Birgitta Olofsson ,  Kari Alitalo ,  Katri Pajusola

    IPC分类号： C07K1622

    CPC分类号： C07K14/52 ,  A61K38/00

    摘要： VEGF-B polypeptides from the PDGF family of growth factors having the property of promoting mitosis and proliferation of vascular endothelial cells, DNA sequences encoding these polypeptides, pharmaceutical compositions containing them and antibodies which react with them. The VEGF-B polypeptides are useful in stimulating angiogenesis as well as in diagnostic applications.

    摘要翻译： 具有促进血管内皮细胞有丝分裂和增殖的生长因子的PDGF家族的VEGF-B多肽，编码这些多肽的DNA序列，含有它们的药物组合物和与它们反应的抗体。 VEGF-B多肽可用于刺激血管发生以及诊断应用。