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    PERSONALIZED TONGUE-MACHINE-INTERFACE
    61.
    发明申请
    PERSONALIZED TONGUE-MACHINE-INTERFACE 有权

    公开(公告)号：US20220296163A1

    公开(公告)日：2022-09-22

    申请号：US17636265

    申请日：2020-08-18

    Applicant: Universität Basel Vizerektorat Forschung

    Inventor： Jeanette von Jackowski ,  Tino Töpper ,  Bekim Osmani ,  Bert Müller

    IPC: A61B5/00 ,  A61F5/56 ,  B33Y80/00 ,  G06F3/01

    Abstract: For exploiting novel use-cases, in particular sophisticated human-machine interaction, with an intraoral electronic tongue monitoring system designed to be worn by a user on the upper or lower jaw and featuring a support sheet bearing a number of intraoral sensors arranged in an array for recording tongue movement and/or tongue pressure, it is proposed that the system comprises at least one extraoral sensor located outside of the oral cavity delimited by the teeth when the system is in place, in particular such that extraoral and/or intraoral and/or interlabial movements of the tongue and/or lip pressure can be recorded with the system and/or such that the system may be used as an input device controlled through tongue movement using a human-machine-interface provided by the system.

    DEVICE AND METHOD FOR COMMINUTION OF CIRCULATING TUMOR CELL CLUSTERS
    63.
    发明申请
    DEVICE AND METHOD FOR COMMINUTION OF CIRCULATING TUMOR CELL CLUSTERS 有权

    公开(公告)号：US20210196309A1

    公开(公告)日：2021-07-01

    申请号：US16078705

    申请日：2018-07-06

    Applicant: Griesmühle Kleinkraftwerk GmbH ,  Universität Basel ,  Johannes Kepler Universität Linz

    Inventor： Nicola Aceto ,  Werner Baumgartner ,  Kurt Priesner

    IPC: A61B17/3207

    Abstract: Device and method for comminution or inactivation of circulating tumor cells (CTC) or tumor cell clusters (CTCC) from a tumor-affected organ or organ part, wherein it is proposed that in the venous drain of the tumor-affected organ or organ part a pump (2) with a pressure-increasing section and a pressure-reducing throttle (13) is arranged and is operated at the output side in its design point given by volumetric flow (Q) and pumping pressure (p) according to the volumetric flow and the blood pressure of the venous drain of the tumor-affected organ or organ part. Circulating tumor cells (CTC) and tumor cell clusters (CTCC) are thus comminuted and inactivated to thus reduce the risk of metastasis formation in cancerous diseases.

    Method for providing sub-elements of a multipart implant or a multipart osteosynthesis
    64.
    发明授权
    Method for providing sub-elements of a multipart implant or a multipart osteosynthesis 有权

    公开(公告)号：US11045321B2

    公开(公告)日：2021-06-29

    申请号：US16083627

    申请日：2017-03-10

    Applicant: UNIVERSITÄT BASEL VIZEREKTORAT FORSCHUNG

    Inventor： Stefan Stübinger ,  Timo Zillig

    IPC: A61F2/28 ,  A61F2/30

    Abstract: A method for providing sub-elements of a multipart implant or a multi-part osteosynthesis prior to introducing same into a human and/or animal body, involves: A) detecting data of a patient for whom the implant and/or the osteosynthesis is intended; B) generating a model using the detected data; C) generating manufacture specifications for at least two or more sub-elements which can be combined so as to form an implant and/or an osteosynthesis on the basis of the generated model, said manufacture specifications comprising C1) a dimensioning of the sub-elements; and D) manufacturing the sub-elements on the basis of the manufacture specifications. The sub-elements can be assembled together so as to form an implant or an osteosynthesis.

    Apparatus and method for determining the orientation and position of two rigid bodies
    65.
    发明授权
    Apparatus and method for determining the orientation and position of two rigid bodies 有权

    公开(公告)号：US10914578B2

    公开(公告)日：2021-02-09

    申请号：US16470497

    申请日：2017-12-15

    Applicant: UNIVERSITÄT BASEL

    Inventor： Philippe C. Cattin ,  Lorenzo Iafolla ,  Lilian Witthauer

    IPC: G01B11/26 ,  A61B1/005 ,  G01D5/28 ,  G02B23/24

    Abstract: An apparatus for determining a position and orientation of first and second rigid bodies in relation to each other. The apparatus includes a light source mounted to the first rigid body, an image sensor mounted to either the first or second rigid body and positioned in a field of light, a shadow mask mounted to either the first or second rigid body and arranged in the field of light, and a computation unit configured to calculate at least one angle by evaluating a shadow image which passes the shadow mask and is detected by the image sensor. The apparatus may include a mechanical constraint mounted to the first and second rigid bodies that defines a fixed distance between the first and second rigid bodies, is stationary in relation to one of the first or second rigid body, and is variably inclinable in relation to the other.

    MEDICAL ENDODEVICE
    67.
    发明申请
    MEDICAL ENDODEVICE 审中-公开

    公开(公告)号：US20200170707A1

    公开(公告)日：2020-06-04

    申请号：US16624990

    申请日：2018-06-25

    Applicant: UNIVERSITÄT BASEL

    Inventor： Manuela EUGSTER ,  Patrick WEBER ,  Georg RAUTER

    IPC: A61B18/24 ,  A61B34/30

    Abstract: A medical endodevice (1) for an intervention inside a human or animal body comprises an elongated liaising structure (2) having a distal end arrangeable inside a body of the human or animal being and a proximal end arrangeable outside the body while the distal end is inside the body. The endodevice has an intervention tool arranged to manipulate a target tissue (51) inside the human or animal body. The intervention tool is arranged at the distal end (23) of the liaising structure (2). The endodevice (1) further comprises a positioning unit (3) having a moving formation (32) arranged to dislocate the intervention tool relative to the target tissue (51), and an anchoring formation arranged to fix the moving formation (32) to a fixing tissue (51) inside the human or animal body such that the target tissue (51) is positioned in a workspace of the intervention tool.

    CONTROLLING A SURGICAL INTERVENTION TO A BONE
    70.
    发明申请
    CONTROLLING A SURGICAL INTERVENTION TO A BONE 审中-公开
    控制骨科手术干预

    公开(公告)号：US20170007328A1

    公开(公告)日：2017-01-12

    申请号：US15113636

    申请日：2015-01-30

    Applicant: UNIVERSITÄT BASEL ,  UNIVERSITÄTSSPITAL BASEL

    Inventor： Philippe Cattin ,  Gregory Jost ,  Jonas Walti

    IPC: A61B34/10 ,  G05B15/02 ,  A61B34/20

    CPC classification number: A61B34/10 ,  A61B34/20 ,  A61B2017/00221 ,  A61B2017/564 ,  A61B2034/107 ,  A61B2034/2048 ,  A61B2034/2068 ,  A61B2090/364 ,  G05B15/02

    Abstract: A method of controlling a surgical intervention to a bone (31) comprises: obtaining a three-dimensional image or multiplanar reconstruction of the bone (31), defining a position and an axis of intervention on the three-dimensional image or multi-planar reconstruction of the bone (31), and controlling the orientation of an intervention instrument (1) equipped with an orientation sensor (2) during the surgical intervention by evaluating a signal provided by the orientation sensor (2). The method further comprises referencing the intervention instrument (1) with respect to the bone (31) before the surgical intervention by arranging the intervention instrument (1) along an anatomic landmark (32) being an edge of the bone (31) and rotating the orientation sensor (2) into a predefined position, or by arranging the intervention instrument (1) essentially perpendicular to an anatomic landmark (32) being an essentially flat surface of the bone (31) and rotating the orientation sensor (2) into a predefined position. The method according to the invention allows for efficiently achieving correct orientation and position of the intervention instrument in a bone surgical intervention. Furthermore, the method according to the invention provides an efficient real-time control at comparably low efforts. Still further, with the method according to the invention radiation exposure to the operational staff as well as patients can be reduced.

    Abstract translation: 控制对骨骼（31）的外科手术的方法包括：获得骨骼（31）的三维图像或多平面重建，在三维图像或多平面重建上定义干涉的位置和轴线 ，并且通过评估由所述取向传感器（2）提供的信号来控制在手术介入期间配备有方位传感器（2）的介入器械（1）的取向。 该方法还包括通过沿着作为骨骼（31）的边缘的解剖标志（32）布置介入器械（1），在外科手术之前相对于骨头（31）参考介入器械（1） 或者通过将干涉仪器（1）基本上垂直于作为骨骼（31）的基本上平坦的表面的解剖学标记（32）布置并将定向传感器（2）旋转到预定义的位置 位置。 根据本发明的方法允许在骨手术介入中有效地实现干预器械的正确取向和位置。 此外，根据本发明的方法在相当低的努力下提供了有效的实时控制。 此外，根据本发明的方法，可以减少对操作人员以及患者的辐射照射。

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