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61.发明申请Sheaths Reducing Recoil and Loss of Retention for Polymer Scaffolds Crimped to Balloons 有权护套降低了压缩和气泡失效的聚合物支架公开(公告)号：US20140157567A1
公开(公告)日：2014-06-12
申请号：US13708638
申请日：2012-12-07
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Yunbing Wang , Jhoan Bayogo
IPC: A61M25/00
CPC classification number: A61F2/0095 , A61F2/958 , A61F2/962 , A61F2/97 , A61F2002/011 , A61F2002/9522 , A61F2002/9583 , A61F2240/001 , A61F2250/0059 , B23P11/005 , Y10T29/49826 , Y10T29/49838 , Y10T29/49909 , Y10T29/49915
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A single piece sheath is placed over the scaffold immediately following crimping of the scaffold to the balloon. The single piece sheath is replaced by a two-piece sheath, which is removed prior to performing a medical procedure using the medical device.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 在将支架压合到气囊之后立即将单件护套放置在支架上方。 单件护套由两件式护套代替，其在使用医疗装置执行医疗程序之前被移除。
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公开(公告)号：US20140110885A1
公开(公告)日：2014-04-24
申请号：US14139740
申请日：2013-12-23
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Xiao Ma , Fuh-Wei Tang , Ni Ding
IPC: B29C35/02
CPC classification number: B29C71/02 , A61F2/82 , A61F2/915 , A61F2002/91558 , A61F2002/91583 , A61F2210/0004 , A61F2240/001 , A61L2/007 , A61L2/08 , A61L2/087 , A61L31/06 , A61L31/148 , A61L2202/21 , A61L2202/24 , A61L2400/18 , B29C35/02 , B29C2035/0877 , B29C2071/022 , B29L2031/753 , C08J7/08 , C08J7/123 , C08J2367/04 , C08L67/04
Abstract: Methods are disclosed for conditioning a polymeric stent after sterilization, and/or after crimping and before packaging, such that the properties of the polymeric stent fall within a narrower range of values. The stent is exposed to a controlled temperature at or above ambient for a period of time after radiation sterilization and/or after crimping and before sterilization. As a result, the polymeric stent properties, particularly radial strength and number-average molecular weight of the polymer of the polymeric stent, fall within a narrower range.
Abstract translation: 公开了用于在灭菌后和/或在卷曲之后和包装之前调节聚合物支架的方法，使得聚合物支架的性质落在较窄的值范围内。 在辐射灭菌后和/或在压接之后和灭菌之前将支架暴露于等于或高于环境的受控温度一段时间。 结果，聚合物支架的聚合物支架性质，特别是聚合物支架的聚合物的径向强度和数均分子量落在更窄的范围内。
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公开(公告)号：US20140046006A1
公开(公告)日：2014-02-13
申请号：US13941374
申请日：2013-07-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , David C. Gale , Bin Huang , Mikael O. Trollsas , Thierry Glauser , Florian Ludwig
IPC: C08L67/04
Abstract: Implantable medical devices fabricated from branched polymers are disclosed.
Abstract translation: 公开了由支化聚合物制造的可植入医疗器械。
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公开(公告)号：US20140033506A1
公开(公告)日：2014-02-06
申请号：US14032144
申请日：2013-09-19
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Kevin F. Jow , Arlene Sucy Yang , Yunbing Wang , Kathleen W. Yan
IPC: A61F2/958
CPC classification number: B29C65/72 , A61F2/89 , A61F2/915 , A61F2/958 , A61F2002/825 , A61F2002/91575 , A61F2210/0004 , A61F2210/0061 , B29C47/0004 , B29C47/0023 , B29C65/02 , B29C65/565 , B29C66/534 , B29K2067/046 , B29K2105/0085 , B29K2995/0056 , B29L2031/7532 , B29L2031/7543 , Y10T29/49863 , Y10T29/49865 , Y10T29/49913 , Y10T29/49925 , Y10T29/49927 , Y10T29/49929 , Y10T156/1005
Abstract: A medical device—includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen.
Abstract translation: 一种医疗装置 - 包括卷曲到具有膨胀气囊的导管的聚合物支架。 将支架通过包括将支架加热到低于聚合物玻璃化转变温度的温度的方法来卷曲到气囊，以改善支架保持，而不会在稍后部署以支撑体腔时对支架的机械特性产生不利影响。
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公开(公告)号：US20140008007A1
公开(公告)日：2014-01-09
申请号：US14024572
申请日：2013-09-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Luis Vazquez , Hung T. Nguyen , Scott H. Mueller , Kathleen Yan
IPC: B29D23/00
CPC classification number: A61F2/82 , A61F2/95 , A61F2/958 , A61F2002/91566 , A61F2002/9522 , A61F2250/0067 , B29C53/30 , B29C67/0014 , B29D23/00 , B29D23/001 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , Y10T29/4994 , Y10T29/49945 , Y10T29/53996
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.
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Patent Agency Ranking
66.发明申请公开(公告)号：US20130324676A1
公开(公告)日：2013-12-05
申请号：US13959651
申请日：2013-08-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang
CPC classification number: A61L31/06 , A61L31/041 , Y10T428/1352 , C08L67/04
Abstract: Medical devices, such as stents, fabricated at least in part from a polymer composite including a biodegradable elastomeric phase dispersed within a biodegradable polymeric matrix are disclosed. The composite is composed of a polyurethane block copolymer including soft polymer blocks and a hard polymer blocks.
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67.发明申请METHOD OF IMPROVING FRACTURE TOUGHNESS OF IMPLANTABLE MEDICAL DEVICES THROUGH ANNEALING 有权通过退火改善可植入医疗器械的断裂韧性的方法公开(公告)号：US20130207314A1
公开(公告)日：2013-08-15
申请号：US13794537
申请日：2013-03-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , James Oberhauser
IPC: B29C51/00
CPC classification number: B29C51/002 , A61L31/06 , A61L31/14 , Y10T29/49 , C08L67/04
Abstract: Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing are disclosed herein. A polymeric construct is annealed with no or substantially no crystal growth to increase nucleation density. After the annealing, crystallites are grown around the formed nuclei. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the crystallite growth.
Abstract translation: 本文公开了通过退火制造具有改善的断裂韧性的聚合物可植入装置的方法。 将聚合物构件退火，没有或基本上没有晶体生长以增加成核密度。 退火后，在形成的核周围生长微晶。 在微晶生长之后，可由聚合物构造体制造诸如支架的可植入医疗装置。
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公开(公告)号：US20180154585A1
公开(公告)日：2018-06-07
申请号：US15828253
申请日：2017-11-30
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Xiao Ma , Rommel Lumauig
Abstract: A medical device includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen. A variable diameter sheath with a central portion that prevents expansion of the stent when the balloon is pressurized and larger diameter ends is disposed over the crimped stent-balloon assembly. The balloon is pressurized and the larger diameter ends of the sheath allow the balloon beyond the ends of the stent to expand. The balloon is then depressurized.
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公开(公告)号：US20180116830A1
公开(公告)日：2018-05-03
申请号：US15851561
申请日：2017-12-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang
Abstract: A medical device includes a polymer stent scaffold crimped to a catheter having an expansion balloon. A process for forming the medical device includes placing the scaffold on a support supported by an alignment carriage, and deionizing the scaffold to remove any static charge buildup on the scaffold before placing the scaffold within a crimper to reduce the scaffold's diameter. The polymer scaffold is heated to a temperature below the polymer's glass transition temperature to improve scaffold retention without adversely affecting the mechanical characteristics of the scaffold when deployed to support a body lumen.
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公开(公告)号：US09895241B2
公开(公告)日：2018-02-20
申请号：US14280476
申请日：2014-05-16
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang
CPC classification number: A61F2/82 , A61F2/915 , A61F2/958 , A61F2002/91533 , A61F2002/91566 , A61F2002/9522 , A61F2210/0071 , Y10T29/49865 , Y10T29/49885 , Y10T29/49908 , Y10T29/49909 , Y10T29/49913 , Y10T29/49915 , Y10T29/49927 , Y10T29/53657
Abstract: A medical device includes a polymer stent scaffold crimped to a catheter having an expansion balloon. A process for forming the medical device includes placing the scaffold on a support supported by an alignment carriage, and deionizing the scaffold to remove any static charge buildup on the scaffold before placing the scaffold within a crimper to reduce the scaffold's diameter. The polymer scaffold is heated to a temperature below the polymer's glass transition temperature to improve scaffold retention without adversely affecting the mechanical characteristics of the scaffold when deployed to support a body lumen.
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