摘要:
Methods of treating an eye of a human or animal include administering to an eye of a human or animal a composition in the form of an emulsion including water, a hydrophobic component and a cyclosporin component in a therapeutically effective amount of less than 0.1% by weight of the composition. The weight ratio of the cyclosporin component to the hydrophobic component is less than 0.8.
摘要:
A liquid comprising a therapeutically effective concentration of a cyclosporin and a vitamin E tocopherol polyethylene glycol succinate, wherein said liquid is an emulsion. is disclosed herein. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein.
摘要:
An integrated receiver with channel selection and image rejection substantially implemented on a single CMOS integrated circuit is described. A receiver front end provides programable attenuation and a programable gain low noise amplifier. Frequency conversion circuitry advantageously uses LC filters integrated onto the substrate in conjunction with image reject mixers to provide sufficient image frequency rejection. Filter tuning and inductor Q compensation over temperature are performed on chip. The filters utilize multi track spiral inductors. The filters are tuned using local oscillators to tune a substitute filter, and frequency scaling during filter component values to those of the filter being tuned. In conjunction with filtering, frequency planning provides additional image rejection. The advantageous choice of local oscillator signal generation methods on chip is by PLL out of band local oscillation and by direct synthesis for in band local oscillator. The VCOs in the PLLs are centered using a control circuit to center the tuning capacitance range. A differential crystal oscillator is advantageously used as a frequency reference. Differential signal transmission is advantageously used throughout the receiver.
摘要:
Systems and methods for dynamically limiting total colorant coverage in multi-colorant rendering. Two polyhedra are defined: one contains all the colors that exceed the total colorant limit, and another is within the colorant limit that contains the results of the colorant limitation process. Data is received to identify a specified contone color, which is processed to decide whether it is inside one of the polyhedra. If the specified contone color is not within either polyhedra, the specified contone color is used in the rendering process. Alternatively, if the specified contone color is within one of the polyhedra, the value representing the specified contone color is compressed into the second polyhedra volume to obtain a resultant contone color that is used in the rendering process.
摘要:
Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.
摘要:
A device for detecting an actuator assembly parking error when a disc drive is powered on includes a magnetic latch attached to the actuator assembly and a latch pin assembly electrically connected to a base plate in the disc drive, where the latch pin assembly is positioned to contact the magnetic latch only when the actuator's read/write head is positioned over a parking zone on the disc. A detection module is electrically connected to the magnetic latch and thus is able to detect whether or not the magnetic latch is contacting the latch pin assembly when the disc drive is powered on. A method for detecting an actuator assembly parking error includes powering on the disc drive, determining whether the magnetic latch has electrical contact with the latch pin assembly, and reporting a parking error if the magnetic latch does not have electrical contact with the latch pin assembly.
摘要:
A method and system for monitoring and compensating the performance of an operational circuit is provided. The system includes one or more integrated circuit chips and a controller. Each integrated circuit chip includes one or more operational circuits, each operational circuit having at least one controllable circuit parameter. Each integrated circuit chip also includes a process monitor module at least partially constructed thereon. The controller is coupled to each process monitor module and to each operational circuit. The controller includes logic for evaluating the performance of an operational circuit based on data obtained from process monitor module and operational circuit related data stored in a memory. Based on the evaluation, the controller determines whether any deviations from desired or optimal performance of the circuit exist. If deviations exist, the controller generates a control signal to initiate adjustments to the operational circuit to compensate for the deviations.
摘要:
Methods of treating an eye of a human or animal include administering to an eye of a human or animal a composition in the form of an emulsion including water, a hydrophobic component and a cyclosporin component in a therapeutically effective amount of less than 0.1% by weight of the composition. The weight ratio of the cyclosporin component to the hydrophobic component is less than 0.8.