公开(公告)号：US20090010306A1

公开(公告)日：2009-01-08

申请号：US11773547

申请日：2007-07-05

申请人： Yasuhiro Egami ,  Uwe Frey ,  Christian Klein ,  Jurgen Quest ,  Uwe Beifuss ,  Vladimir Ondrus

发明人： Yasuhiro Egami ,  Uwe Frey ,  Christian Klein ,  Jurgen Quest ,  Uwe Beifuss ,  Vladimir Ondrus

IPC分类号： G01K11/00

CPC分类号： C09K11/06 ,  C09D5/22 ,  C09D175/04 ,  C09K9/02 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/185 ,  F21K2/04

摘要： A temperature sensitive paint comprises a binder for forming a polymer matrix, a transition metal complex embedded in the binder and displaying a temperature dependent fluorescence, the fluorescence of the transition metal complex showing a maximum relative temperature sensitivity per Kelvin at a first temperature, and a rare earth complex also embedded in the binder and displaying a temperature dependent fluorescence, the fluorescence of the rare earth complex showing a maximum relative temperature sensitivity per Kelvin at a second temperature. The second temperature is higher than the first temperature by 50 to 150 Kelvin so that the overall temperature range covered by both complexes as temperature probes is extended.

摘要翻译： 温度敏感性涂料包括用于形成聚合物基质的粘合剂，嵌入粘合剂中的过渡金属络合物并显示温度依赖性荧光，过渡金属络合物的荧光在第一温度下显示出每开氏度的最大相对温度敏感度，以及 稀土配合物也嵌入粘合剂中并显示温度依赖性荧光，稀土配合物的荧光在第二温度下显示出每开氏度的最大相对温度敏感度。 第二温度高于第一温度50至150开尔文，使得作为温度探针的两个络合物覆盖的总体温度范围延长。

公开(公告)号：US20080189976A1

公开(公告)日：2008-08-14

申请号：US11748089

申请日：2007-05-14

申请人： Lothar Krell ,  Gerald Caspers ,  Christian Klein

发明人： Lothar Krell ,  Gerald Caspers ,  Christian Klein

IPC分类号： F26B17/00 ,  F26B25/00

CPC分类号： F26B17/104 ,  A23K10/38 ,  A23L3/40 ,  A23L3/50 ,  C12F3/06 ,  F26B3/08 ,  Y02P60/873

摘要： This invention relates to a process and an appliance for drying byproducts from the processing of starch-containing and sugar-containing raw materials, in particular, after their fermentation and distillation, where the byproduct is fractionated in a purification phase with a high liquid proportion and a thick phase, whereby the thick phase is shaped into particles in a conditioning procedure and whereby these particles are dried in a fluidized-bed drying system with a relative gap volume, in the fluidized-bed layer, between 0.5 and 0.92.

公开(公告)号：US07276901B2

公开(公告)日：2007-10-02

申请号：US11191839

申请日：2005-07-28

申请人： Christian Klein ,  Tobias Ernst

发明人： Christian Klein ,  Tobias Ernst

IPC分类号： G01R19/00

CPC分类号： G01K7/16 ,  G01K15/00 ,  G01R31/2829

摘要： For monitoring a sensor using differential voltage evaluation for detecting a short circuit to ground and/or to supply voltage UB, a first resistor and a second resistor R1, R2 are assigned to the sensor, a sum voltage is determined from voltages UP, UM at terminals of the sensor, the sum voltage is compared to supply voltage UB, a ratio a of determined sum voltage to supply voltage UB is then calculated, and depending on the value for the ratio a, the occurrence of a shunt at the positive terminal and/or negative terminal of the sensor is detected.

摘要翻译： 为了监视使用差分电压评估的传感器，用于检测短路对地和/或提供电压U B，第一电阻器和第二电阻器R 1， SUB> 2 被分配给传感器，并且在传感器的端子处由电压U SUB，U M M确定和电压，并且比较和电压 为了提供电压U B，然后计算确定的和电压与电源电压U B B的比率a，并且根据比率a的值，发生 检测传感器的正极端子和/或负极端子处的分流。

公开(公告)号：US06756826B1

公开(公告)日：2004-06-29

申请号：US10460075

申请日：2003-06-12

申请人： Christian Klein ,  James J. McDonald, II

发明人： Christian Klein ,  James J. McDonald, II

IPC分类号： H03B100

CPC分类号： H03K19/01721 ,  H03K17/164

摘要： A buffer circuit with slow output edges is described. Pulsed higher value currents are driven from one shot timing circuits to inject a pulse of current into the control gate of the buffer's output MOSFET to speed up the beginning of the turning on or the turning off of the output MOSFT. When the beginning and turning on and off is reached lower value current sources continue to drive the gate of the output MOSFET. In one embodiment, one shots are triggered from the rising and falling edges of the input signal. The effect of the higher value current pulses is to reduce the circuit delay through the buffer. Also, the pulse width can be designed as temperature sensitive, and supply voltage sensitive so as to maintain the buffer circuit delay as substantially constant as temperature, supply voltage and process variation occur.

摘要翻译： 描述具有缓慢输出边缘的缓冲电路。 脉冲更高值的电流由单稳定时电路驱动，以将脉冲电流注入缓冲器输出MOSFET的控制栅极，以加速导通开始或关闭输出MOSFT。 当达到开始和接通和关断时，电流源继续驱动输出MOSFET的栅极。 在一个实施例中，从输入信号的上升沿和下降沿触发一次。 较高值电流脉冲的影响是减小通过缓冲器的电路延迟。 此外，脉冲宽度可以设计为温度敏感，并且电源电压敏感，以便保持缓冲器电路的延迟基本上恒定，因为温度，电源电压和工艺变化发生。

公开(公告)号：US06660415B2

公开(公告)日：2003-12-09

申请号：US09837748

申请日：2001-04-19

申请人： Christian Klein ,  Martin Schuessler

发明人： Christian Klein ,  Martin Schuessler

IPC分类号： H01M800

CPC分类号： H01M8/04089 ,  H01M8/0612 ,  H01M8/0662

摘要： In a method for improving cold starting of a catalytically active component in gas generation systems for a mobile fuel cell system, a temporary store is arranged directly in the starting-material gas stream. During cold starting, the temporary store stores gaseous constituents from the gaseous starting material, which constituents cause problems when starting, and releases such constituents (which have been stored during the cold-start phase) again as a result of the heating which takes place as operation of the system continues.

公开(公告)号：US06605444B1

公开(公告)日：2003-08-12

申请号：US08898085

申请日：1997-07-22

申请人： Christian Klein ,  Hans-Peter Josel ,  Rupert Herrmann ,  Josef Maier ,  Harald Ertl ,  Helmut Oberpriller ,  Reinhold Hilpert ,  Florian Binder ,  Josef Ritter

发明人： Christian Klein ,  Hans-Peter Josel ,  Rupert Herrmann ,  Josef Maier ,  Harald Ertl ,  Helmut Oberpriller ,  Reinhold Hilpert ,  Florian Binder ,  Josef Ritter

IPC分类号： G01N3353

CPC分类号： G01N33/54386 ,  G01N33/558 ,  Y10S435/97 ,  Y10S435/971 ,  Y10S436/807

摘要： A method is disclosed for obtaining and/or immunologically detecting an analyte contained in a gas phase by immunologically binding the analyte to a binding partner thereof contained in a gas- and liquid-permeable first carrier matrix. Said method is characterized in that a) the analyte-containing gas phase is brought into contact with the first carrier matrix (immune adsorber), b) the analyte is bound to the first binding partner which is contained in the first matrix and not bound to the matrix, and c) the complex of analyte and first binding partner and the free first binding partner are eluted from the first matrix, d) the eluted complex or the free first binding partner is determined as a measure for the amount of analyte present.

摘要翻译： 公开了一种用于通过将分析物与包含在气体和液体可渗透的第一载体基质中的结合配偶体免疫结合来获得和/或免疫检测气相中包含的分析物的方法。 所述方法的特征在于a）使含分析物的气相与第一载体基质（免疫吸附剂）接触，b）分析物与第一个结合配偶体结合，该第一个结合配偶体包含在第一个基质中， 基质和c）分析物和第一结合配偶体和游离的第一结合配偶体的复合物从第一个基质中洗脱出来，d）洗脱的复合物或游离的第一结合配偶体被确定为测定存在的分析物的量。

公开(公告)号：US6159747A

公开(公告)日：2000-12-12

申请号：US27894

申请日：1998-02-23

申请人： Herbert Harttig ,  Christian Klein

发明人： Herbert Harttig ,  Christian Klein

IPC分类号： G01N31/22 ,  G01N21/77 ,  G01N33/52 ,  G01N33/543 ,  G01N33/558

CPC分类号： G01N33/54366 ,  G01N33/521 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/81

摘要： The invention concerns an analytical test element containing an absorbent material with a sample application and detection zone and a blister filled with liquid on a support, wherein the support has a notch within the support surface such that a spike forms there when the support is bent with which the blister can be opened so that liquid escapes and comes into contact with the absorbent material as well as a process for the production of such an analytical test element and a method for determining an analyte by means of such an analytical test element.

摘要翻译： 本发明涉及一种包含吸收材料的分析测试元件，其具有样品施加和检测区域以及在支撑体上填充有液体的泡罩，其中所述支撑件在支撑表面内具有凹口，使得当支撑件与 其可以打开泡罩，使得液体逸出并与吸收材料接触，以及用于生产这种分析测试元件的方法和通过这种分析测试元件确定分析物的方法。

公开(公告)号：US5994552A

公开(公告)日：1999-11-30

申请号：US947065

申请日：1997-10-08

申请人： Rupert Herrmann ,  Hans-Peter Josel ,  Christian Klein ,  Dieter Heindl

发明人： Rupert Herrmann ,  Hans-Peter Josel ,  Christian Klein ,  Dieter Heindl

IPC分类号： C07D513/10 ,  C07F9/6561 ,  C09K11/07 ,  C12Q1/34 ,  G01N33/535 ,  G01N33/58

CPC分类号： C07D513/10 ,  C07F9/6561 ,  C09K11/07 ,  C12Q1/34 ,  G01N33/582

摘要： Compounds of the general formula III, ##STR1## in which R represents ##STR2## and in which R.sub.1 and R.sub.2 are the same or different and represent hydrogen or straight-chained or branched lower alkyl C.sub.1 - C.sub.6, and X represents a cleavable group, at least one of the groups R.sub.4 or R.sub.5 represents a group that stabilizes the dioxetan structure and at most one of the groups R.sub.4 or R.sub.5 represents hydrogen. These compounds can be used as substrates in immunological assays and in DNA diagnostics using activating agents for the formation of colour.

摘要翻译： 通式III的化合物，其中R表示并且其中R 1和R 2相同或不同并且表示氢或直链或支链的低级烷基C 1 -C 6，X表示可切割基团，至少一个基团 R4或R5表示稳定二氧杂环丁烷结构的基团，R4或R5中至少一个表示氢。 这些化合物可用作免疫学测定中的底物，以及使用活化剂形成颜色的DNA诊断。

公开(公告)号：US5976812A

公开(公告)日：1999-11-02

申请号：US896330

申请日：1997-07-17

申请人： Erasmus Huber ,  Christian Klein ,  Rudolf Vogel ,  Bruno Zink ,  Wolfgang Rollinger

发明人： Erasmus Huber ,  Christian Klein ,  Rudolf Vogel ,  Bruno Zink ,  Wolfgang Rollinger

IPC分类号： C07D207/40 ,  C07D207/416 ,  C07D207/44 ,  C07D207/452 ,  G01N33/94 ,  C07C327/22 ,  A61K51/10 ,  C07C323/41 ,  C07K19/00

CPC分类号： C07D207/416 ,  C07D207/452 ,  G01N33/946

摘要： The invention concerns activated amphetamine derivatives, a process for their production as well as their use for producing immunogens or detection conjugates carrying amphetamine groups. A further subject matter of the invention are new conjugates carrying amphetamine groups, a process for the production thereof as well as their use for the production of antibodies or for the determination of amphetamine or derivatives thereof.

摘要翻译： 本发明涉及活化的苯丙胺衍生物，其生产方法以及其用于产生携带安非他明类的免疫原或检测共轭物的用途。 本发明的另一主题是携带安非他明基团的新缀合物，其生产方法以及其用于生产抗体或用于测定苯丙胺或其衍生物的用途。

公开(公告)号：US5595741A

公开(公告)日：1997-01-21

申请号：US278621

申请日：1994-07-21

申请人： Emasmus Huber ,  Christian Klein ,  Hans-Georg Batz ,  Bruno Zink

发明人： Emasmus Huber ,  Christian Klein ,  Hans-Georg Batz ,  Bruno Zink

IPC分类号： G01N33/531 ,  C07D207/44 ,  C07D207/452 ,  C07D239/62 ,  C07D473/08 ,  C07J41/00 ,  C07J43/00 ,  C07K1/13 ,  C07K14/00 ,  C07K19/00 ,  G01N33/535 ,  G01N33/543 ,  C08L77/04 ,  A61K39/385 ,  A61K37/02

CPC分类号： C07D207/452 ,  C07D239/62 ,  C07D473/08 ,  C07J41/0016 ,  C07J43/003 ,  G01N33/54353

摘要： The invention concerns new aminoalkylmaleimides of the general formula I ##STR1## in which R.sub.1 and R.sub.2 are the same or different and represent hydrogen or a C.sub.1 -C.sub.4 alkyl group and A represents a straight-chain or branched, saturated or unsaturated alkylene group with 2 to 6 carbon atoms which is interrupted, if desired, by an oxygen or sulphur atom or a carbonyl group, as well as their corresponding acid addition salts.The present invention also concerns amidoalkylmaleimide derivatives formed from compounds of the general formula I and immunological binding partners. In addition, the invention concerns immunological conjugates which can be produced by reaction of the amidoalkylmaleimide derivatives with peptides or proteins.The subject matter of the present invention are also the corresponding processes of production of the compounds according to the present invention as well as the use of these conjugates in diagnostic methods of determination, in particular in immunoassays.

摘要翻译： 本发明涉及通式Ⅰ（I）的新的氨基烷基马来酰亚胺，其中R 1和R 2相同或不同，表示氢或C 1 -C 4烷基，A代表直链或支链，饱和或不饱和的亚烷基 具有2至6个碳原子的基团，如果需要，由氧或硫原子或羰基中断，以及它们相应的酸加成盐。 本发明还涉及由通式I的化合物和免疫结合配偶体形成的酰氨基烷基马来酰亚胺衍生物。 此外，本发明涉及可通过酰胺基烷基马来酰亚胺衍生物与肽或蛋白质的反应产生的免疫缀合物。 本发明的主题也是根据本发明的化合物的相应制备方法以及这些缀合物在诊断测定方法中的用途，特别是在免疫测定中。