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    Systems and methods for treating glaucoma and systems and methods for imaging a portion of an eye
    62.
    发明授权
    Systems and methods for treating glaucoma and systems and methods for imaging a portion of an eye 有权
    用于治疗青光眼的系统和方法以及用于对眼睛的一部分进行成像的系统和方法

    公开(公告)号：US08230866B2

    公开(公告)日：2012-07-31

    申请号：US12000477

    申请日：2007-12-13

    申请人： Christoph Hauger ,  Peter Andrews ,  Werner Nahm ,  Ralf Kuschnereit ,  Martin Hacker ,  Gabor Scharioth

    发明人： Christoph Hauger ,  Peter Andrews ,  Werner Nahm ,  Ralf Kuschnereit ,  Martin Hacker ,  Gabor Scharioth

    IPC分类号： A61B19/00

    CPC分类号： A61B3/13 ,  A61B3/102 ,  A61B3/14 ,  A61F9/008 ,  A61F2009/00868

    摘要： Systems and methods are described for imaging an eye portion or for treating glaucoma in an eye of a patient. In a first step an optical microscopic image of a portion of the eye is acquired. In the optical microscopic image a distinguishable anatomical structure is identified to predict a location of a volume portion to be imaged three-dimensionally. Three-dimensional imaging of the located volume portion is performed by acquiring an optical coherence tomography image of the located volume portion. The volume portion is treated by either directing a laser beam to the volume portion or inserting an implant based on the OCT-image.

    摘要翻译： 描述了用于对眼部进行成像或用于治疗患者眼睛中的青光眼的系统和方法。 在第一步骤中，获取眼睛的一部分的光学显微镜图像。 在光学显微镜图像中，识别出可区分的解剖结构以预测待三维成像的体积部分的位置。 通过获取定位体积部分的光学相干断层摄影图像来执行定位体积部分的三维成像。 通过将激光束引导到体积部分或基于OCT图像插入植入物来处理体积部分。

    Fluid-dispensing apparatus with controlled tear-off
    65.
    发明授权
    Fluid-dispensing apparatus with controlled tear-off 有权
    流体分配装置具有可控撕裂

    公开(公告)号：US07681759B2

    公开(公告)日：2010-03-23

    申请号：US11138704

    申请日：2005-05-26

    申请人： Peter Andrews

    发明人： Peter Andrews

    IPC分类号： B67D5/30 ,  B01L3/02

    CPC分类号： B05C11/1034

    摘要： Fluid-dispensing apparatus include a fluid-dispensing needle. A gas discharge member is positioned proximate a dispensing end of the needle that is configured to direct a gas towards a fluid tear-off position below the dispensing end of the needle. A controller controls discharge of the gas by the gas discharge member to control dispensing of fluid from the needle. The dispensing control may control an amount of fluid dispensed from the needle and/or tailing off of fluid dispensed from the needle. The amount of fluid dispensed from the needle may be a microliter range volume of a viscous fluid.

    摘要翻译： 流体分配装置包括流体分配针。 气体排出构件定位在针的分配端附近，其配置成将气体引导到针的分配端下方的流体撕开位置。 控制器通过气体排出构件控制气体的排出，以控制从针头排出的流体。 分配控制可以控制从针中分配的流体的量和/或从针头分配的流体的拖尾。 从针头分配的流体的量可以是粘性流体的微升范​​围体积。

    SUBMOUNTS FOR SEMICONDUCTOR LIGHT EMITTING DEVICES AND METHODS OF FORMING PACKAGED LIGHT EMITTING DEVICES INCLUDING DISPENSED ENCAPSULANTS
    68.
    发明申请
    SUBMOUNTS FOR SEMICONDUCTOR LIGHT EMITTING DEVICES AND METHODS OF FORMING PACKAGED LIGHT EMITTING DEVICES INCLUDING DISPENSED ENCAPSULANTS 有权
    用于半导体发光器件的方法和形成包装发光器件的方法，包括分配的封装

    公开(公告)号：US20080191237A1

    公开(公告)日：2008-08-14

    申请号：US12100647

    申请日：2008-04-10

    申请人： Peter Andrews

    发明人： Peter Andrews

    IPC分类号： H01L33/00 ,  H01L21/56

    CPC分类号： H01L33/52 ,  H01L33/486 ,  H01L33/54 ,  H01L2224/32225 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48227 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/10253 ,  H01L2933/005 ,  H01L2924/00014 ,  H01L2924/00

    摘要： A submount for mounting an LED chip includes a substrate, a die attach pad configured to receive an LED chip on an upper surface of the substrate, a first meniscus control feature on the substrate surrounding the die attach pad and defining a first encapsulant region of the upper surface of the substrate, and a second meniscus control feature on the substrate surrounding the first encapsulant region and defining a second encapsulant region of the upper surface of the substrate. The first and second meniscus control features may be substantially coplanar with the die attach pad. A packaged LED includes a submount as described above and further includes an LED chip on the die attach pad, a first encapsulant on the substrate within the first encapsulant region, and a second encapsulant on the substrate within the second encapsulant region and covering the first encapsulant. Method embodiments are also disclosed.

    摘要翻译： 用于安装LED芯片的基座包括：衬底，被配置为在衬底的上表面上接收LED芯片的管芯附接焊盘;围绕裸片安装焊盘的衬底上的第一弯液面控制特征，并且限定第一密封剂区域 并且衬底上的第二弯液面控制特征包围第一密封剂区域并且限定衬底的上表面的第二密封剂区域。 第一和第二弯液面控制特征可以与管芯附接垫基本共面。 封装的LED包括如上所述的基座，并且还包括在芯片附接垫上的LED芯片，在第一密封剂区域内的衬底上的第一密封剂，以及在第二密封剂区域内的衬底上的第二密封剂，并且覆盖第一密封剂 。 还公开了方法实施例。

    Packages for semiconductor light emitting devices utilizing dispensed reflectors and methods of forming the same
    69.
    发明申请
    Packages for semiconductor light emitting devices utilizing dispensed reflectors and methods of forming the same 有权
    使用分配的反射器的半导体发光器件的封装及其形成方法

    公开(公告)号：US20070170454A1

    公开(公告)日：2007-07-26

    申请号：US11336369

    申请日：2006-01-20

    申请人： Peter Andrews

    发明人： Peter Andrews

    IPC分类号： H01L33/00

    CPC分类号： H01L33/52 ,  H01L33/486 ,  H01L33/60 ,  H01L2224/32225 ,  H01L2224/32245 ,  H01L2224/32257 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/10253 ,  H01L2924/00014 ,  H01L2924/00

    摘要： A packaged LED includes a substrate, an LED chip on the upper surface of the substrate, a first encapsulant material, including a reflective material, on the substrate and spaced apart from the LED chip, and a second encapsulant material on the LED chip. A method of forming a packaged LED includes forming a first meniscus control feature on a substrate and defining a first region of the substrate, forming a second meniscus control feature surrounding the first region and defining a second region of the substrate between the first meniscus control feature and the second meniscus control feature, mounting an LED chip within the first region, dispensing a first encapsulant material including a reflective material within the second region, curing the first encapsulant material, dispensing a second encapsulant material on the substrate within the first region, and curing the second encapsulant material.

    摘要翻译： 封装的LED包括衬底，在衬底的上表面上的LED芯片，在衬底上并与LED芯片间隔开的包括反射材料的第一密封剂材料以及LED芯片上的第二密封剂材料。 一种形成封装的LED的方法包括在衬底上形成第一弯液面控制特征并限定衬底的第一区域，形成围绕第一区域的第二弯液面控制特征，并在第一弯液面控制特征 和第二弯液面控制特征，在第一区域内安装LED芯片，在第二区域内分配包括反射材料的第一密封剂材料，固化第一密封剂材料，在第一区域内分配衬底上的第二密封剂材料，以及 固化第二密封材料。

    Modulation of cell phenotype by inhibitory rna
    70.
    发明申请
    Modulation of cell phenotype by inhibitory rna 审中-公开
    通过抑制性rna调节细胞表型

    公开(公告)号：US20070093435A1

    公开(公告)日：2007-04-26

    申请号：US10550499

    申请日：2004-03-25

    申请人： Peter Andrews ,  Paul Gokhale ,  Jim Walsh ,  Maryam Matin

    发明人： Peter Andrews ,  Paul Gokhale ,  Jim Walsh ,  Maryam Matin

    IPC分类号： A61K48/00 ,  C07H21/02 ,  C12N15/00

    CPC分类号： C12N15/1138 ,  A61K38/00 ,  C12N15/113 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53

    摘要： We describe a method to inhibit cell division of hyperproliferative cells, typically cancer cells, by introducing inhibitory RNA (RNAi) into said cells to ablate mRNAs that encode polypeptides involved in cellular processes and including RNAi molecules and vectors including transcription cassettes encoding said RNAi molecules. By application of said RNAi molecules to cancers in vivo it is possible to effect a treatment whereby the cancer cells are killed or otherwise eliminated.

    摘要翻译： 我们描述了通过将抑制性RNA（RNAi）引入所述细胞以消融编码涉及细胞过程的多肽的mRNA并包括RNAi分子和包含编码所述RNAi分子的转录盒的载体的方法来抑制过度增殖细胞（通常为癌细胞）的细胞分裂的方法。 通过将RNAi分子应用于体内的癌症，可以进行治疗，从而杀死或以其他方式消除癌细胞。