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    PROSTHETIC VALVE FOR REPLACING MITRAL VALVE
    61.
    发明申请
    PROSTHETIC VALVE FOR REPLACING MITRAL VALVE 审中-公开

    公开(公告)号：US20190060060A1

    公开(公告)日：2019-02-28

    申请号：US16171263

    申请日：2018-10-25

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Zenyo Oba

    IPC: A61F2/24

    Abstract: A prosthetic mitral valve can include an outer frame, an inner frame, a valve structure, and a sealing member. The outer frame comprises a plurality of first struts arranged in a lattice pattern and defining a first lumen. The outer frame is self-expandable from a compressed state to an expanded state. The inner frame comprises a plurality of second struts arranged in a lattice pattern and defining a second lumen. The inner frame is disposed within the first lumen of the outer frame, is self-expandable from a compressed state to an expanded state. The valve structure comprises three leaflets made from pericardium and is mounted within the second lumen of the inner frame. The sealing member is coupled to and extends radially outwardly from an atrial end of the outer frame and is configured to engage native tissue of the heart on an atrial side of the native mitral valve.

    Prosthetic valve for replacing mitral valve
    63.
    发明授权
    Prosthetic valve for replacing mitral valve 有权
    用于更换二尖瓣的假体瓣膜

    公开(公告)号：US09433500B2

    公开(公告)日：2016-09-06

    申请号：US14801713

    申请日：2015-07-16

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Oba

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/246 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0063

    Abstract: A prosthetic apparatus configured for implantation in the native mitral valve region of the heart includes a main body that is self-expandable from a compressed state to a radially expanded state. The prosthetic apparatus comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body for capturing a native valve leaflet between the anchor and an outer surface of the main body. In one preferred method of implantation, the prosthetic apparatus is rotated within the native mitral valve region such that a portion of the anchor moves horizontally behind adjacent chordae for anchoring the prosthetic apparatus in the native mitral valve.

    Abstract translation: 构造成用于植入心脏的天然二尖瓣区域的假体装置包括从压缩状态向径向展开状态自扩张的主体。 假体装置包括耦合到主体并且设置在主体外部的至少一个心室锚，用于捕获锚固体和主体的外表面之间的天然瓣膜。 在一种优选的植入方法中，假体装置在天然二尖瓣区域内旋转，使得锚的一部分水平地移动到相邻的腱索之后，以将假体装置锚定在天然二尖瓣中。

    Heart valve sealing devices
    64.
    发明授权
    Heart valve sealing devices 有权
    心脏瓣膜密封装置

    公开(公告)号：US09414918B2

    公开(公告)日：2016-08-16

    申请号：US14019332

    申请日：2013-09-05

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Chau ,  Travis Oba ,  Sergio Delgado ,  Robert C. Taft

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/243 ,  A61F2/2433 ,  A61F2/2442 ,  A61F2/2445 ,  A61F2/2454 ,  A61F2/2457 ,  A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2230/0069 ,  A61F2250/0003

    Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.

    Abstract translation: 本公开总体上涉及用于帮助密封天然心脏瓣膜并防止或减少反流的假体装置和相关方法，以及用于植入这种假体装置的装置和相关方法。 在一些情况下，具有单个锚的间隔物可以植入天然心脏瓣膜内。 在一些情况下，具有双重锚的间隔物可以植入天然心脏瓣膜内。 在某些情况下，可以使用装置来延长天然心脏瓣膜小叶的有效长度。

    SYSTEMS FOR QUICKLY DELIVERING A PROSTHETIC HEART VALVE
    65.
    发明申请
    SYSTEMS FOR QUICKLY DELIVERING A PROSTHETIC HEART VALVE 有权
    用于快速输送前置心脏瓣膜的系统

    公开(公告)号：US20150216656A1

    公开(公告)日：2015-08-06

    申请号：US14684267

    申请日：2015-04-10

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

    Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

    Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 人造瓣膜可以是市售的，具有缝合环的阀门，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。 提供了基于导管的系统和部署方法。

    Unitary quick-connect prosthetic heart valve deployment system
    66.
    发明授权
    Unitary quick-connect prosthetic heart valve deployment system 有权
    单一快速连接假体心脏瓣膜部署系统

    公开(公告)号：US09005277B2

    公开(公告)日：2015-04-14

    申请号：US13723799

    申请日：2012-12-21

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2439 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/005 ,  A61F2250/006

    Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.

    Abstract translation: 提供了一种快速连接的心脏瓣膜假体，可以在手术过程中快速方便地植入。 心脏瓣膜包括基本上不可膨胀的不可压缩的人造瓣膜和塑性可扩张的联接支架，从而使得能够在不缝合的情况下连接到环形空间。 可以提供少量的导向缝线用于主动脉瓣取向。 假体瓣膜可以是具有连接有联接支架的缝合环的市售阀。 联接支架可以从锥形展开形状扩展到圆锥形膨胀形状，并且可以包括连接在轴向延伸柱之间的腹板状支柱。 用于展开的系统和方法包括气球导管通过的中空两件式手柄。 与心脏瓣膜一起存储阀保持器，并且手柄容易地附接到其上以改善阀门准备步骤。

    DEVICE AND METHOD FOR REPLACING MITRAL VALVE
    68.
    发明申请
    DEVICE AND METHOD FOR REPLACING MITRAL VALVE 审中-公开
    用于更换麻药阀的装置和方法

    公开(公告)号：US20130053950A1

    公开(公告)日：2013-02-28

    申请号：US13660875

    申请日：2012-10-25

    Applicant: Edwards Lifesciences Corporation

    Inventor： Stanton J. Rowe ,  Mark Chau ,  Son V. Nguyen

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61B17/0401 ,  A61B2017/00243 ,  A61B2017/0417 ,  A61B2017/0496 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2/2454 ,  A61F2/2457 ,  A61F2/90 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2250/0039 ,  A61L27/3625 ,  A61L27/50 ,  A61L2430/20

    Abstract: A prosthetic mitral valve assembly is disclosed. The assembly comprises a radially-expandable stent including a lower portion sized for deployment between leaflets of a native mitral valve and an upper portion having a flared end. The upper portion is sized for deployment within the annulus of the mitral valve and the flared end is configured to extend above the annulus. The stent is formed with a substantially D-shape cross-section for conforming to the native mitral valve. The D-shape cross-section includes a substantially straight portion for extending along an anterior side of the native mitral valve and a substantially curved portion for extending along a posterior side of the native mitral valve. The assembly further includes a valve portion formed of pericardial tissue and mounted within an interior portion of the stent for occluding blood flow in one direction.

    Abstract translation: 公开了一种假体二尖瓣组件。 该组件包括径向可扩张的支架，其包括尺寸适于在天然二尖瓣的小叶之间展开的下部和具有扩张端的上部。 上部的尺寸设计成用于展开在二尖瓣的环形区域中，并且扩口端构造成在瓣环之上延伸。 支架形成有大致D形的横截面，以符合天然二尖瓣。 D形截面包括用于沿着天然二尖瓣的前侧延伸的基本上直的部分和用于沿着天然二尖瓣的后侧延伸的基本上弯曲的部分。 组件还包括由心包组织形成并安装在支架的内部部分内的阀部分，用于阻止沿一个方向的血流。

    QUICK-CONNECT PROSTHETIC HEART VALVE AND METHODS
    69.
    发明申请
    QUICK-CONNECT PROSTHETIC HEART VALVE AND METHODS 有权
    快速连接心脏瓣膜和方法

    公开(公告)号：US20130053949A1

    公开(公告)日：2013-02-28

    申请号：US13660780

    申请日：2012-10-25

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Quinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

    Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

    Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 假体阀可以是具有缝合环的市售阀，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。

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