公开(公告)号：US5312966A

公开(公告)日：1994-05-17

申请号：US944359

申请日：1992-09-14

申请人： Takafumi Abe ,  Yoshiyuki Nishide ,  Nobuyuki Muro ,  Hirofumi Higuchi

发明人： Takafumi Abe ,  Yoshiyuki Nishide ,  Nobuyuki Muro ,  Hirofumi Higuchi

IPC分类号： B01J31/08 ,  C07B61/00 ,  C07C67/20 ,  C07C67/36 ,  C07C69/14 ,  C07C69/54 ,  C07C69/675 ,  C07C231/08 ,  C07C233/03 ,  C07C69/34 ,  C07C69/68

CPC分类号： C07C67/20

摘要： There is disclosed a process for efficiently producing a carboxylic acid ester and formamide by reacting a carboxylic acid amide with a formic acid ester or with an alcohol and carbon monoxide in the presence of a strongly basic anion-exchange resin. By the use of the strongly basic anion-exchange resin as the catalyst, the process of the present invention enables the efficient production of the carboxylic acid ester as well as formamide from the Carboxylic acid amide and Formic acid ester, etc. with a high selectivity under mild reaction conditions and facilitates the separation of the catalyst from the reaction product, thereby greatly enhancing the industrial significance of itself.

摘要翻译： 公开了在强碱性阴离子交换树脂存在下，使羧酸酰胺与甲酸酯或与醇和一氧化碳反应，有效地制备羧酸酯和甲酰胺的方法。 通过使用强碱性阴离子交换树脂作为催化剂，本发明的方法能够以高选择性从羧酸酰胺和甲酸酯等有效地制备羧酸酯以及甲酰胺 在温和的反应条件下，促进了催化剂与反应产物的分离，从而大大增强了其自身的工业意义。

公开(公告)号：US09221171B2

公开(公告)日：2015-12-29

申请号：US14343526

申请日：2012-08-28

申请人： Makiko Sugiura ,  Hirofumi Higuchi

发明人： Makiko Sugiura ,  Hirofumi Higuchi

IPC分类号： G01L1/00 ,  G01L1/16 ,  B25J9/16 ,  G01B17/00 ,  B06B1/06 ,  B25J13/08 ,  G01L5/22 ,  G01L1/25

CPC分类号： B25J9/1612 ,  B06B1/0674 ,  B25J13/082 ,  G01B17/00 ,  G01L1/16 ,  G01L1/162 ,  G01L1/255 ,  G01L5/226

摘要： A complex device includes: a substrate having a thick portion, a cavity and a membrane for bridging the cavity; and multiple piezoelectric elements having a lower electrode, a piezoelectric film and an upper electrode. A part of the piezoelectric elements has a projecting portion arranged on the upper electrode. The part of piezoelectric elements (30) provides a vertical pressure detection element. The piezoelectric elements further have an ultrasonic element other than the vertical pressure detection element. The ultrasonic element is arranged over at least the cavity of the substrate in a horizontal direction.

摘要翻译： 复杂装置包括：具有厚部分的基底，用于桥接空腔的空腔和膜; 以及具有下电极，压电膜和上电极的多个压电元件。 压电元件的一部分具有布置在上电极上的突出部分。 压电元件（30）的一部分提供垂直压力检测元件。 压电元件还具有除垂直压力检测元件以外的超声波元件。 超声波元件在水平方向上至少布置在基板的空腔上。

公开(公告)号：US20110014213A1

公开(公告)日：2011-01-20

申请号：US12810939

申请日：2008-12-26

申请人： Masaharu Torikai ,  Daisuke Ishikawa ,  Toshihiro Nakashima ,  Hirofumi Higuchi ,  Fumihiko Sakai ,  Nobuchika Yamamoto ,  Hirotada Fujita ,  Katsunari Taguchi

发明人： Masaharu Torikai ,  Daisuke Ishikawa ,  Toshihiro Nakashima ,  Hirofumi Higuchi ,  Fumihiko Sakai ,  Nobuchika Yamamoto ,  Hirotada Fujita ,  Katsunari Taguchi

IPC分类号： A61K39/395 ,  C07K16/28 ,  C07H21/04 ,  C12N15/63 ,  C12N5/10 ,  C12P21/02 ,  A61P19/02

CPC分类号： C07K16/2839 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/52 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2319/00

摘要： The present invention provides a human anti-α9 integrin antibody or an antibody fragment which specifically recognize human α9 integrin and mouse α9 integrin, inhibit interaction with their ligands, particularly, the antibody or antibody fragment which recognize loop regions of human and mouse α9 integrins, a gene encoding the antibody or antibody fragment, a recombinant expression vector containing the gene, a transformant harboring the gene, production method of human anti-α9 integrin antibody or antibody fragment using the transformant, and an agent for the prophylaxis or treatment of rheumatoid arthritis which contains the antibody or antibody fragment.

摘要翻译： 本发明提供一种人抗α9整联蛋白抗体或特异性识别人α9整联蛋白和小鼠α9整联蛋白的抗体片段，抑制与其配体的相互作用，特别是识别人和小鼠α9整联蛋白环区的抗体或抗体片段， 编码抗体或抗体片段的基因，含有该基因的重组表达载体，携带该基因的转化体，使用该转化体的人抗α9整联蛋白抗体的制备方法或抗体片段，以及预防或治疗类风湿性关节炎 其含有抗体或抗体片段。

公开(公告)号：US07418863B2

公开(公告)日：2008-09-02

申请号：US11528606

申请日：2006-09-28

申请人： Hirofumi Higuchi

发明人： Hirofumi Higuchi

IPC分类号： G01P1/02

CPC分类号： G01C19/5719

摘要： An angular rate sensor includes a base member serving as a base, an angular rate sensing element having a vibrating member, a wiring member having a flexible, electrical insulating tape portion and a electrical wire portion. The wiring member has end portions fixed to the base member and a middle portion positioned between the end portions. The middle portion is separated from the base member and the sensing element is mounted to the middle portion. Thus, due to an elasticity of the wiring member, the sensing element can be isolated from an external vibration.

摘要翻译： 角速率传感器包括用作基座的基座构件，具有振动构件的角速度检测元件，具有柔性电绝缘带部分和电线部分的布线构件。 布线构件具有固定到基部构件的端部和位于端部之间的中间部分。 中间部分与基部部件分离，并且感测元件安装到中间部分。 因此，由于布线构件的弹性，感测元件可以与外部振动隔离。

公开(公告)号：US20070199377A1

公开(公告)日：2007-08-30

申请号：US11653344

申请日：2007-01-16

申请人： Takashi Katsumata ,  Takeshi Ito ,  Hirofumi Higuchi ,  Mitsuhito Ogino ,  Tetsuya Morishima

发明人： Takashi Katsumata ,  Takeshi Ito ,  Hirofumi Higuchi ,  Mitsuhito Ogino ,  Tetsuya Morishima

IPC分类号： G01P15/125

CPC分类号： G01C19/5719

摘要： An angular velocity sensor includes first and second vibrators having a movable portion with driving and detecting purpose movable electrodes and a fixed portion with first and second side driving and detecting purpose fixed electrodes. The driving voltages applied to the first side driving purpose fixed electrode in the first vibrator is a first driving voltage including direct and alternating voltages. The driving voltage applied to the second side driving purpose fixed electrode in the first vibrator is a second driving voltage including direct and alternating voltages. At least one of the direct voltages, one of the alternating voltages, or one of duty ratios of the first and second driving voltages is controlled so that the first vibrator vibrates opposite to the second vibrator.

摘要翻译： 角速度传感器包括第一振动器和第二振动器，该第一振动器和第二振动器具有带有驱动和检测目的的可移动电极的可移动部分和具有第一和第二侧驱动和检测目的的固定电极的固定部分。 施加到第一振动器中的第一侧驱动用固定电极的驱动电压是包括直流和交流电压的第一驱动电压。 施加到第一振动器中的第二侧驱动用固定电极的驱动电压是包括直流和交流电压的第二驱动电压。 控制直流电压中的至少一个，交流电压之一或第一和第二驱动电压的占空比中的一个，使得第一振动器与第二振动器相反地振动。

公开(公告)号：US07159462B2

公开(公告)日：2007-01-09

申请号：US11075708

申请日：2005-03-10

申请人： Hirofumi Higuchi

发明人： Hirofumi Higuchi

IPC分类号： G01P15/125

CPC分类号： G01C19/5762

摘要： An oscillator is oscillatable in a predetermined direction. First and second driving electrodes are secured to the base and apply an electrostatic force to the oscillator to make drive oscillation of the oscillator in the predetermined direction. At the time of the drive oscillation of the oscillator, a predetermined electric charge is accumulated in the oscillator, and electric charges of opposite polarities are alternately and periodically accumulated in the first and second driving electrodes, respectively, to exert an attractive force between the oscillator and a corresponding one of the first and second driving electrodes and also to exert a repulsive force between the oscillator and the other one of the first and second driving electrodes, and vice versa.

公开(公告)号：US20060255694A1

公开(公告)日：2006-11-16

申请号：US11489682

申请日：2006-07-20

申请人： Hirofumi Higuchi

发明人： Hirofumi Higuchi

IPC分类号： G01P15/125 ,  H01L41/00

CPC分类号： G01C19/5762

摘要： An oscillator is oscillatable in a predetermined direction. First and second driving electrodes are secured to the base and apply an electrostatic force to the oscillator to make drive oscillation of the oscillator in the predetermined direction. At the time of the drive oscillation of the oscillator, a predetermined electric charge is accumulated in the oscillator, and electric charges of opposite polarities are alternately and periodically accumulated in the first and second driving electrodes, respectively, to exert an attractive force between the oscillator and a corresponding one of the first and second driving electrodes and also to exert a repulsive force between the oscillator and the other one of the first and second driving electrodes, and vice versa.

摘要翻译： 振荡器可在预定方向上振荡。 第一驱动电极和第二驱动电极固定到基座并向振荡器施加静电力，以使振荡器在预定方向上的驱动振荡。 在振荡器的驱动振荡时，在振荡器中累积预定的电荷，相反极性的电荷分别交替地周期地累积在第一和第二驱动电极中，以在振荡器之间施加吸引力 以及第一和第二驱动电极中的相应一个，并且还在振荡器和第一和第二驱动电极中的另一个之间施加排斥力，反之亦然。

公开(公告)号：US20060112764A1

公开(公告)日：2006-06-01

申请号：US11239084

申请日：2005-09-30

申请人： Hirofumi Higuchi

发明人： Hirofumi Higuchi

IPC分类号： G01P9/04

CPC分类号： G01C19/5719

摘要： An angular velocity detector includes a disk-shaped inertial mass supported on a substrate via driving beams and a second mass connected to the inertial mass via detecting beams. The inertial mass is oscillated in its rotational direction around a center axis (z) by an electrostatic force. When an angular velocity around a detection axis (x), which is perpendicular to the center axis (z), is imposed on the second mass while the inertial mass is oscillating, the second mass displaces in the direction parallel to the center axis (z). A capacitance between the second mass and the substrate changes according to the displacement of the second mass. The angular velocity is detected based on the changes in the capacitance. Since the driving beams allow the inertial mass to oscillate only in the rotational direction, the driving beams can be easily designed and manufactured.

摘要翻译： 角速度检测器包括通过驱动梁支撑在基板上的盘形惯性质量块，以及通过检测梁连接到惯性质量块的第二质量块。 惯性质量通过静电力围绕中心轴线（z）以其旋转方向摆动。 当惯性质量正在振荡时，围绕垂直于中心轴线（z）的检测轴（x）的角速度施加在第二质量上时，第二质量沿平行于中心轴线（z ）。 第二质量块和基板之间的电容根据第二质量块的位移而变化。 基于电容的变化来检测角速度。 由于驱动梁允许惯性质量仅在旋转方向上振荡，因此可以容易地设计和制造驱动梁。

公开(公告)号：US06993969B2

公开(公告)日：2006-02-07

申请号：US10808544

申请日：2004-03-25

申请人： Hirofumi Higuchi

发明人： Hirofumi Higuchi

IPC分类号： G01C19/56

CPC分类号： G01C19/5719

摘要： An oscillation type of micro gyro sensor equipped with two vibrators is provided. The gyro sensor has a monitoring electrode, a signal processor, and a driving electrode attached to both the vibrators. The monitoring electrode monitors a vibration of only one of the two vibrators to output signal indicative of the monitored vibration. The signal processor drives the two vibrators in mutually opposite phases, by using the signal from said monitoring electrode. The driving electrode drives both the vibrators on the basis of the two driving signals.

摘要翻译： 提供了配有两个振动器的微型陀螺传感器的振荡型。 陀螺仪传感器具有监测电极，信号处理器和连接到两个振动器的驱动电极。 监视电极仅监测两个振动器中的一个的振动，以输出指示所监视的振动的信号。 信号处理器通过使用来自所述监控电极的信号来驱动两个相互相反相位的振动器。 驱动电极基于两个驱动信号驱动振动器。

公开(公告)号：US6121939A

公开(公告)日：2000-09-19

申请号：US961767

申请日：1997-10-31

申请人： Hiroaki Imaizumi ,  Koji Sakauchi ,  Shuji Hagiwara ,  Hirofumi Higuchi ,  Ryotaro Manabe

发明人： Hiroaki Imaizumi ,  Koji Sakauchi ,  Shuji Hagiwara ,  Hirofumi Higuchi ,  Ryotaro Manabe

IPC分类号： H01Q1/24 ,  H01Q3/18 ,  H01Q5/00 ,  H01Q5/45 ,  H01Q11/08 ,  H01Q13/06 ,  H01Q19/12 ,  H01Q19/17 ,  H01Q21/24 ,  H01Q25/00 ,  H01Q13/00

CPC分类号： H01Q25/007 ,  H01Q1/247 ,  H01Q11/08 ,  H01Q13/065 ,  H01Q19/12 ,  H01Q19/17 ,  H01Q21/245 ,  H01Q25/00 ,  H01Q3/18 ,  H01Q5/45

摘要： When a converter 14 is rotated via a rotation mechanism 17, the arrangement inclination angle of two primary radiators 15a and 15b can be adjusted in the range of 0 to 20 deg. with respect to an axis which is in parallel with the ground. Also the reception polarization angle due to probes of the primary radiators 15a and 15b can be adjusted in the range of 0 to 20 deg. while maintaining a preset difference in polarization angle among the satellites. Therefore, the arrangement inclination angle of the primary radiators 15a and 15b for respectively receiving signals from the two satellites, and the reception polarization angle in the primary radiators 15a and 15b can be simultaneously easily adjusted by rotating the converter 14 via the rotation mechanism 17.