公开(公告)号：US20070255292A1

公开(公告)日：2007-11-01

申请号：US11786787

申请日：2007-04-12

申请人： Marcus Pfister

发明人： Marcus Pfister

IPC分类号： A61B19/00

CPC分类号： A61B6/5235 ,  A61B6/12 ,  A61B6/4233 ,  A61B6/4441 ,  A61B6/466 ,  A61B90/11 ,  A61B2090/376

摘要： A puncturing needle holder is attached to a flat-panel x-ray detector such that it is visible in the x-ray image as a point. The point can involve the crossing area of two struts, which are attached to the flat-panel x-ray detector. Mappings are created in which on the one hand a region of the body to be punctured and on the other hand the point created by the puncturing needle holder are mapped by the x-ray images created with the flat-panel x-ray detector. The x-ray C-arm is moved until such time as precisely the puncturing needle holder is shown in the mapping so that it points to the region of the body to be punctured. Subsequent puncturing can then be carried out in a number of different ways.

摘要翻译： 穿刺针保持器附接到平板X射线检测器，使得其作为点在x射线图像中是可见的。 该点可以涉及附接到平板X射线检测器的两个支柱的交叉区域。 产生映射，其一方面是要被穿刺的身体的区域，另一方面，由穿刺针保持器产生的点由通过平板X射线检测器产生的X射线图像进行映射。 X射线C臂移动直到在映射中精确地示出了穿刺针保持器，使得它指向被刺穿的身体的区域。 随后的穿刺可以以多种不同的方式进行。

公开(公告)号：US20070167721A1

公开(公告)日：2007-07-19

申请号：US11636953

申请日：2006-12-11

申请人： Marcus Pfister ,  Norbert Rahn

发明人： Marcus Pfister ,  Norbert Rahn

IPC分类号： A61B5/05

CPC分类号： A61B6/504 ,  A61B6/12 ,  G06T5/50 ,  G06T7/33 ,  G06T7/38 ,  G06T2207/10072 ,  G06T2207/10121 ,  G06T2207/20221 ,  G06T2207/30101

摘要： The present invention relates to a method and a device for correcting motion in imaging during a medical intervention, by which method a 3D tomographic image of a target area for the intervention is first recorded while there are one or more medical instruments in the target area that will remain there during the intervention. During the intervention 2D fluoroscopic images of the target area are recorded and registered with the 3D image. The registration is therein adjusted for each 2D fluoroscopic image in realtime based in each case on the one or more instruments. The 2D fluoroscopic images are then in each case visualized with representations, concurring in terms of perspective, of the 3D image. Virtually error-free overlaying of the 3D image with in each case one 2D fluoroscopic image can be implemented using the present method and associated device.

摘要翻译： 本发明涉及一种用于在医疗介入期间校正成像中的运动的方法和装置，通过该方法首先记录用于干预的目标区域的3D断层图像，同时目标区域中存在一个或多个医疗器械 将在干预期间留在那里。 在干预期间，记录2D目标区域的二维透视图像并将其与3D图像一起登记。 在每个情况下，在一个或多个仪器上实时地对每个2D透视图像进行配准。 然后，2D透视图像在每种情况下可视化，并以透视方式同意3D图像。 在每种情况下，3D图像的几乎无误差的重叠可以使用本方法和相关联的装置来实现一个2D透视图像。

公开(公告)号：US20060249690A1

公开(公告)日：2006-11-09

申请号：US11375948

申请日：2006-03-15

申请人： Marcus Pfister ,  Wolfgang Strob

发明人： Marcus Pfister ,  Wolfgang Strob

IPC分类号： H05B33/00

CPC分类号： G01N21/6456 ,  A61B5/0059 ,  A61B5/415 ,  A61B5/418 ,  G01N2201/0221

摘要： An apparatus detects fluorescence. The apparatus, also known as a fluorescence scanner, includes an image detector, which is embodied for detecting image data in the wavelength range of fluorescent light, and an excitation light source, which is embodied for generating light in a wavelength range suitable for exciting the fluorescence. The apparatus has a guide beam projector, which is embodied for generating a guide beam from light in the visible wavelength range. The guide beam is aimed such that a projection of the guide beam, a region that is detectable by the image detector is displayed. The guide beam allows exact viewing of a body region to be examined possible for the surgeon, which is not possible on the basis only of the light for exciting a fluorescence, at least whenever the excitation light is in the non-visible wavelength range, such as IR or NIR, or is generated directly during the recording of the fluorescence image.

公开(公告)号：US20050203420A1

公开(公告)日：2005-09-15

申请号：US11007492

申请日：2004-12-08

申请人： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

发明人： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

IPC分类号： G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  A61B5/055 ,  A61B6/03 ,  A61B8/00 ,  G06T1/00 ,  G06T7/00 ,  A61B6/00

CPC分类号： A61B5/0073 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/055 ,  A61B6/032 ,  A61B6/5247 ,  A61B8/00 ,  A61B8/5238 ,  G06K9/32 ,  G06K2209/05 ,  G06T7/38

摘要： The invention relates to a method for the merged display of first image information captured using a first imaging device with second image information captured using a second imaging device, whereby said image information relates to the same area of examination in the human or animal body, in particular a hollow organ, in which method: a plurality of individual, two-dimensional images of the area under examination are recorded in the form of fluorescence images by light-excitation of fluorescent areas of the area under examination, using a medical instrument to be introduced invasively into the area under examination, in particular a catheter, a 3D fluorescence image data record, suitable for the three-dimensional reconstruction of a fluorescence three-dimensional image of the area under examination, is generated from the individual two-dimensional images, a further 3D image data record of the area under examination recorded using a further examination procedure, said further 3D image data record being suitable for the three-dimensional reconstruction of a further three-dimensional image of the area under examination, is used, the 3D fluorescence image data record and the further 3D image data record are registered with one another, and one or more fluorescence-optically marked, relevant areas of the examination volume, on the basis of the mapping rules determined by the registration process, are displayed on a monitor, said areas being accurately positioned in the further three-dimensional image generated using the further 3D data record, whereby either a) one or more fluorescence-optically marked, relevant areas of the area under examination are identified in the 3D fluorescence image data record in terms of their spatial position, and only these extracted partial image areas are displayed, said extracted partial image areas being accurately positioned in the further three-dimensional image, or b) the complete fluorescence three-dimensional image is superimposed over the further three-dimensional image, with voxels having predefined gray-scale values being masked out.

公开(公告)号：US20050165303A1

公开(公告)日：2005-07-28

申请号：US11012971

申请日：2004-12-14

申请人： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

发明人： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

IPC分类号： G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  A61B5/06 ,  A61B19/00 ,  A61M25/00 ,  A61B5/05

CPC分类号： A61B5/0071 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/06 ,  A61B5/062 ,  A61B5/7285 ,  A61B34/20 ,  A61B90/36 ,  A61B90/361 ,  A61B2034/2051 ,  A61B2090/367 ,  A61B2090/373

摘要： Catheter device comprising a catheter, in particular an intravascular catheter, for insertion into an area being examined, in particular into a vessel or cavity-containing organ in the body of a person or animal, wherein in the area of the catheter tip a device (3) is provided for emitting excitation light for light-optically exciting an area being examined surrounding said catheter tip, furthermore a device (3) is provided for collecting response light emitted, owing to excitation, from the area being examined, and furthermore a position sensor (13, 24, 27) is provided enabling said catheter tip's spatial position and/or orientation to be registered in a system of coordinates of a position-registering system (7, 14).

摘要翻译： 导管装置，其包括导管，特别是血管内导管，用于插入被检查的区域，特别是插入人或动物身体中的血管或含空腔的器官中，其中在导管末端的区域中， 3）用于发射用于光学激发围绕所述导管尖端的被检查区域的激发光，此外，设备（3）用于从被检查的区域收集由于激发而发射的响应光，并且还提供位置 传感器（13,24,27）被设置成能够使所述导管尖端的空间位置和/或取向登记在位置登记系统（7,14）的坐标系中。

公开(公告)号：US10595795B2

公开(公告)日：2020-03-24

申请号：US14503356

申请日：2014-09-30

申请人： Marcus Pfister

发明人： Marcus Pfister

IPC分类号： A61B6/12 ,  A61B6/03 ,  G06T7/30 ,  A61B6/00

摘要： An angiographic examination method for depicting a target region as an examination object using an angiography system includes capturing a volume data set of the target region with the examination object, registering the volume data set to a C-arm, and extracting information about an assumed course of the examination object in the volume data set. The method also includes generating a 2D projection image of a medical instrument in the target region, 2D/3D merging the 2D projection image and the registered volume data set for generating a 2D overlay image, and detecting the instrument in the 2D overlay image with a first projection matrix. The method includes generating a virtual 2D projection using a virtual projection matrix, 3D reconstructing the instrument, and distorting at least part of the reference image such that the current and the assumed course of vessels are made to be congruent.

公开(公告)号：US20180279974A1

公开(公告)日：2018-10-04

申请号：US15942992

申请日：2018-04-02

申请人： Katharina Breininger ,  Marcus Pfister

发明人： Katharina Breininger ,  Marcus Pfister

IPC分类号： A61B6/12 ,  A61B6/00

摘要： Methods and systems are provided for determining a stiffness information of a medical instrument used during a minimally invasive interventional procedure in a vascular system of a patient by recording a three-dimensional volume image of the vascular system at least in the intervention region.

公开(公告)号：US08219183B2

公开(公告)日：2012-07-10

申请号：US11977110

申请日：2007-10-23

申请人： Michael Maschke ,  Marcus Pfister

发明人： Michael Maschke ,  Marcus Pfister

IPC分类号： A61B6/00

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/02007 ,  A61B5/7425

摘要： A generation of sectional images of tissue is provided. In this arrangement a first light-conducting fiber of a device for generating sectional tissue images according to the optical coherence tomography principle, which light-conducting fiber is rotatably accommodated within a catheter tube, is additionally connected to a device for generating light in a further wavelength range and for detecting fluorescent light. With its use sectional tissue images produced according to the optical coherence tomography principle can be superimposed with fluorescent images.

摘要翻译： 提供了一代组织的剖面图像。 在这种布置中，用于根据光学相干断层摄影原理产生部分组织图像的装置的第一导光纤维，该光学相干断层摄影原理将导光纤维可旋转地容纳在导管内，另外连接到用于产生光的装置 波长范围和用于检测荧光灯。 使用根据光学相干断层摄影原理产生的截面组织图像可以与荧光图像叠加。

公开(公告)号：US20120089003A1

公开(公告)日：2012-04-12

申请号：US12900082

申请日：2010-10-07

申请人： Martin Ostermeier ,  Marcus Pfister

发明人： Martin Ostermeier ,  Marcus Pfister

IPC分类号： A61B5/05

CPC分类号： A61B6/5223 ,  A61B6/032 ,  A61B6/12 ,  A61B6/4085 ,  A61B6/4441 ,  A61B6/487 ,  A61B6/488 ,  A61B6/504 ,  A61B6/5235 ,  A61F2/95 ,  G06T15/08 ,  G06T19/00 ,  G06T2210/41 ,  G06T2215/06

摘要： In a method for a fluoroscopy controlled insertion of a stent into a curved aorta of a patient for aneurysm repair, a 3D volume image is obtained of the patient's aorta at the aneurysm. By knowing a registration of the 3D volume image to a C-arm of an angiographic system and projection geometry of the angiography system, the 3D volume images are projected atomically correct to a 2D fluoroscopy image of the angiography system. For the 2D3D overlay, the 3D volume image is displayed as a curved planar reconstruction in which the 2D fluoroscopy image and the 3D volume image are warped around a curved center line of the patient's curved aorta or around a curved guide instrument center line to correct for the curvature of the aorta so that the previously curved aorta center line or curved center line of the guide instrument turns into a straight line. The 2D3D overlay is used to visualize the insertion of the stent.

摘要翻译： 在用于荧光透视的控制性插入支架到用于动脉瘤修复的患者的弯曲主动脉中的方法中，获得了动脉瘤患者主动脉的3D体积图像。 通过将3D体积图像注册到血管造影系统的C臂和血管造影系统的投影几何结构，3D体积图像被投影原子校正到血管造影系统的2D透视图像。 对于2D3D叠加，3D体积图像被显示为弯曲平面重建，其中2D透视图像和3D体积图像围绕患者弯曲主动脉的弯曲中心线或围绕弯曲导向仪器中心线扭曲，以校正 主动脉的曲率，使得导向仪器的先前弯曲的主动脉中心线或弯曲的中心线变成直线。 2D3D叠层用于可视化支架的插入。

公开(公告)号：US08041095B2

公开(公告)日：2011-10-18

申请号：US12136862

申请日：2008-06-11

申请人： Ashraf Mohamed ,  Marcus Pfister

发明人： Ashraf Mohamed ,  Marcus Pfister

IPC分类号： G06K9/00 ,  G06K9/46 ,  G06K9/52

CPC分类号： A61B17/12022 ,  A61B5/02007 ,  A61B5/1076 ,  A61B6/4441 ,  A61B6/504 ,  A61B17/12118 ,  A61B17/1214 ,  A61B2017/00712 ,  A61B2017/00725 ,  G06T7/62 ,  G06T17/00 ,  G06T2207/10072 ,  G06T2207/30016 ,  G06T2207/30101

摘要： The present invention relates to a method and apparatus for pretreatment planning endovascular coil placement, comprising steps of: a) analyzing three-dimensional data enabling visualization of a volume of interest containing at least a part of a blood vessel with an aneurysm; b) determining the centerline of the vessel; c) determining the aneurysm diameter; d) determining the aneurysm dome height; e) creating a three-dimensional surface model of the aneurysm in the vessel, using the results from the previous steps; f) estimating the volume expansion of one or more coils with the aid of said surface model; and g) visual simulating at least one according to the estimated virtual coil being to place inside the aneurysm.

摘要翻译： 本发明涉及一种用于预处理规划血管内线圈放置的方法和装置，包括以下步骤：a）分析能够使包含至少一部分具有动脉瘤的血管的感兴趣体积的可视化的三维数据; b）确定船只的中心线; c）确定动脉瘤直径; d）确定动脉瘤圆顶高度; e）使用前面步骤的结果创建血管内动脉瘤的三维表面模型; f）借助于所述表面模型估计一个或多个线圈的体积膨胀; 以及g）根据估计的虚拟线圈将至少一个放置在动脉瘤内部的视觉模拟。